Koutoku
Hiroshi Koutoku, Chuo-Ku JP
Patent application number | Description | Published |
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20090263390 | METHOD OF TREATING CANCER BY CO-ADMINISTRATION OF ANTICANCER AGENTS - The present invention relates to a method of treating cancer by co-administration of an effective amount of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin -2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide and an effective amount of one or more anticancer agents selected from the group consisting of carboplatin, cisplatin, paclitaxel, vinorelbine, gemcitabine, irinotecan, docetaxel, doxorubicin, dacarbazine and rituximab, or a retuximab-containing combination therapy selected from R-ICE and R-DHAP. The treatment method of the present invention is useful for the treatment for all solid tumors and lymphomas, preferably skin cancer, bladder cancer, breast cancer, uterine cancer, ovary cancer, prostate cancer, lung cancer, colon cancer, pancreas cancer, renal cancer, gastric cancer and the like. Particularly, they are expected as therapeutic agents for tumor types which show resistance against existing anticancer agents. | 10-22-2009 |
Kouichi Koutoku, Kanagawa JP
Patent application number | Description | Published |
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20100084063 | PNEUMATIC TIRE - In a pneumatic tire, a difference Gs-Ge falls in a range of Gs-Ge≧0.10, where Gs is a groove area ratio for a wear rate 0% and Ge is a groove area ratio for a wear rate 100%. Further, a groove area ratio G for a wear rate 20% falls in a range of (Gs-G)/(Gs-Ge)≧0.30, and a groove area ratio G for a wear rate 35% falls in a range of (Gs-G)/(Gs-Ge)≧0.50. | 04-08-2010 |
20110056603 | PNEUMATIC RADIAL TIRE AND PROCESS FOR PRODUCING RETREADED TIRE - A pneumatic radial tire includes: at least one carcass layer suspended across left and right bead parts; a belt layer arranged on an outer circumferential side of the carcass layer; and a tread arranged on an outer circumferential side of the belt layer. The tread has a laminated structure in which a thermoplastic film layer of a thermoplastic resin or a thermoplastic elastomer composition is interposed between a tread-side rubber layer and a belt layer-side rubber layer. The thermoplastic elastomer composition is obtained by blending an elastomer in a thermoplastic resin. A process for producing a retreaded tire includes the steps of: forming a base tire from the pneumatic radial tire by softening the thermoplastic film layer through heating so as to separate and remove the tread-side rubber layer, the pneumatic radial tire having the tread worn away; and subsequently bonding a new tread-side rubber layer onto the base tire. | 03-10-2011 |
Kouichi Koutoku, Hiratsuka-Shi JP
Patent application number | Description | Published |
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20150114536 | Pneumatic Tire - A pneumatic tire includes a carcass layer, a belt layer that is disposed on the outer side in the tire radial direction of the carcass layer, and a tread rubber that is disposed on the outer side in the tire radial direction of the belt layer. The pneumatic tire also includes at least three circumferential main grooves extending in the tire circumferential direction, and a plurality of land portions that are defined by these circumferential main grooves. The belt layer includes an inner-side cross belt and outer-side cross belt having belt angles of not less than 51° and not more than 80° as absolute values with respect to the tire circumferential direction, the belt angles having mutually opposite signs, and a circumferential reinforcing layer having a belt angle that satisfies a range of ±5° with respect to the tire circumferential direction. | 04-30-2015 |