Patent application number | Description | Published |
20090117002 | NANOPARTICLE ASSEMBLIES WITH MOLECULAR SPRINGS - A nanoscale sensing device from different types of nanoparticles (NPs) and nanowires (NWs) connected by molecular springs. The distance between the nanoscale colloids reversibly changes depending on conditions or analyte concentration and can be evaluated by fluorescence measurements. | 05-07-2009 |
20100098902 | Layer-by-layer assemblies having preferential alignment of deposited axially anisotropic species and methods for preparation and use thereof - Methods are provided for making layer-by-layer assemblies that comprise axial geometry nanoparticles. Such methods include forming a first layer on a substrate that comprises an axial nanoparticle, forming a second layer on the substrate that comprises an axial nanoparticle, where the first and second layers are aligned to respective first and second orientations. The disclosure also provides for multilayer materials having a first layer including a first polyelectrolyte and a first axial geometry nanoparticle which is substantially aligned along a first orientation. The multilayer material also includes a second layer including a second polyelectrolyte and a second axial geometry nanoparticle species having axial geometry, where the second nanoparticle species is substantially aligned along a second orientation which is distinct from the first orientation. | 04-22-2010 |
20100189913 | ROLLING CONTACT LAYER-BY-LAYER ASSEMBLY - A rolling contact layer-by-layer assembly device comprises at least one roller, a cylinder substrate and a motor to rotate the cylinder substrate. The assembly device optionally includes at least one rinsing nozzle and air applicator. The rollers each provide a polyelectrolyte solution to the surface of the cylinder substrate, the polyelectrolyte solutions having an affinity for each other. Excess polyelectrolyte solution can be washed using the rinsing nozzle followed by a drying step prior to the application of the second polyelectrolyte solution. A plurality of bilayers is produced by the continuous application of polyelectrolyte solutions to form an LBL article such as a nano-composite article or film. The film is then removed from the surface of the cylinder substrate. | 07-29-2010 |
20120276278 | MEDICAL DEVICES HAVING ANTIMICROBIAL COATINGS THEREON - The present invention provides a medical device, preferably a contact lens, which a core material and an antimicrobial metal-containing LbL coating that is not covalently attached to the medical device and can impart to the medical device an increased hydrophilicity. The antimicrobial metal-containing coating on a contact lens of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial and a low toxicity, while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial metal-containing LbL coating thereon. | 11-01-2012 |
Patent application number | Description | Published |
20090041825 | Cell culture well-plates having inverted colloidal crystal scaffolds - An artificial bone marrow construct comprising a substrate having at least one well; a three dimensional biocompatible polymer matrix comprising a transparent polymer network containing microspherical voids, wherein the microspherical voids are each connected to at least one other void through inter-connecting pores; at least one LBL coating on a surface of at least one of the polymer network, voids and pores, a population of bone marrow cells comprising stem cells and stromal cells; and at least one bioactive agent. An artificial immune network comprising a polymer matrix with a population of immune cells comprising B-cells and T-cells is disclosed. Methods for testing the toxicity of drugs and other agents against bone marrow cells and methods for making universal blood using the artificial bone marrow constructs are also disclosed. | 02-12-2009 |
20090121727 | ELECTRICAL IMPEDANCE TOMOGRAPHY OF NANOENGINEERED THIN FILMS - The present teachings relate to the application of electrical impedance tomography (EIT) to demonstrate the multifunctionality of carbon nanocomposite thin films under various types of environmental stimuli. Carbon nanotube (CNT) thin films are fabricated by a layer-by-layer (LbL) technique or other techniques and mounted with electrodes along their boundaries. The response of the thin films to various stimuli determined by relying on electric current excitation and corresponding boundary potential measurements. The spatial conductivity variations are reconstructed based on a mathematical model for the EIT technique. Here, the ability of the EIT method to provide two-dimensional mapping of the conductivity of CNT thin films is validated by (1) electrically imaging intentional structural defects in the thin films and (2) mapping the film's response to various pH environments. | 05-14-2009 |
20090121872 | PASSIVE WIRELESS READOUT MECHANISMS FOR NANOCOMPOSITE THIN FILM SENSORS - A method for sensing a stimulus comprising providing a sensing assembly having a first structure and a second structure, wherein the first structure is made of a material different than the second structure and each of the first structure and the second structure is nanoscale. The method further includes providing an inductive antenna operably coupled to the sensing assembly, disposing the sensing assembly upon a spatial area, exposing the sensing assembly to the stimulus thereby producing a detectable change in the sensing assembly, and wirelessly coupling a reader with the inductive antenna to obtain a signal representative of the detectable change in the sensing assembly. | 05-14-2009 |
20100248361 | PLATELET PRODUCTION METHODS - The present invention provides platelet production methods. The method comprises the steps of providing a cellular material and culturing the cellular material, wherein platelets are produced. The culturing may be performed on 2D or 3D cell support structure or in suspension culture. In some embodiments, all or a part of the 2D or 3D culturing may be performed in a bioreactor. In some embodiments, the method may further comprise a step of isolating a subset of cells from the starting cellular material, wherein the isolated subset of cells is then cultured, wherein platelets are produced. In yet other embodiments, the method comprises the steps of providing a cellular material, isolating a subset of cells, seeding the subset of cells into a 3D scaffold, culturing the subset of cells in a 3D scaffold, seeding the cultured subset of cells into a bioreactor, culturing the subset of cells in a bioreactor, and harvesting the cells from the bioreactor, wherein platelets are produced. | 09-30-2010 |
20100273667 | Cell culture well-plates having inverted colloidal crystal scaffolds - A three dimensional inverted colloidal crystal scaffold is described which comprises a substrate having at least one well. The scaffold also includes a three dimensional matrix comprising a transparent biocompatible polymeric network containing microspherical voids. The microspherical voids are each connected to at least one other void through inter-connecting pores. Additionally, an apparatus for producing such a colloidal crystal scaffold is described. Methods for making the inverted colloidal crystal scaffold, for using the scaffold and for identifying the effects of a drug, pharmaceutical or toxin on a living cell using the inverted colloidal crystal scaffold are also disclosed. | 10-28-2010 |
20110024158 | CARBON-NANOTUBE/GRAPHENE-PLATELET-ENHANCED, HIGH-CONDUCTIVITY WIRE - A conductive wire includes an aramid fiber and at least one layer attached about the aramid fiber, the at least one layer including at least one of aligned carbon nanotubes and graphene platelets. | 02-03-2011 |
20110250427 | ULTRASTRONG AND STIFF LAYERED POLYMER NANOCOMPOSITES AND HIERARCHICAL LAMINATE MATERIALS THEREOF - A stiff layered polymer nanocomposite comprising a substrate adapted to receive a plurality of alternating layers of a first material and a second material; wherein the first material and second material are a polyelectrolyte, an organic polymer or an inorganic colloid and said first material and said second material have a chemical affinity for each other, said plurality of layers crosslinked using a chemical or physical crosslinking agent. Thin films that are consolidated and optionally crosslinked can be manufactured into hierarchical laminates with rigid and stress resistant properties. | 10-13-2011 |
20120156389 | PREPARATION OF LAYER-BY-LAYER MATERIALS AND COATINGS FROM IONIC LIQUIDS - A method for making a layered material can include providing a substrate having a surface with at least one region having a charge and forming layers by sequentially contacting the at least one region with a first solution and a second solution. The first solution comprises a first layering material in an ionic liquid and the second solution comprises a second layering material in a second ionic solution. The first and second layering materials can have a chemical affinity to each other. The first layering material and/or the second layering material can include polyelectrolytes, polymers, carbon nanotubes, or combinations thereof. | 06-21-2012 |
20130090542 | IMPLANTABLE MICRO-COMPONENT ELECTRODES - The present disclosure provides robust implantable micro-component electrodes that can be used in a variety of medical devices. The medical device may be a neural probe that can monitor or stimulate neural activity in an organism's brain, spine, nerves, or organs, for example. The micro-component electrode has a small physical profile, with ultra-thin dimensions, while having high strength and flexibility. The micro-electrode has an electrically conductive core material, e.g., carbon. The surface of the core material includes one or more electrically conductive regions coated with an electrically conductive material and one or more non-conductive regions having an electrically non-conductive biocompatible polymeric coating. Implantable devices having such micro-components are capable of implantation in an organism for very long durations. | 04-11-2013 |
20130288050 | SYNTHESIS AND USE OF ARAMID NANOFIBERS - Dissociation of a macroscale version of an aramid fiber leads to the nanofiber form of this polymer. Indefinitely stable dispersions of uniform high-aspect-ratio aramid nanofibers (ANFs) with diameters between 3 and 30 nm controlled by the media composition and up to 10 μm in length are obtained. ANFs can be processed in transparent thin films using layer-by-layer assembly (LBL) with superior mechanical performance. | 10-31-2013 |
20130320273 | NANOCOMPOSITES FOR NEURAL PROSTHETICS DEVICES - Implantable electrically conductive devices are provided having a nanocomposite material coating comprising gold nanoparticles or carbon nanotubes. Such an implantable device may be a neural or other implantable prosthesis, including microelectrodes for use in vivo. The devices may have dimensions on a cellular scale. Further, the devices may be highly flexible and electrically conductive, while also having low impedance and high storage charge capacity. Layer-by-layer methods for fabricating such nanocomposite materials for implantable devices are also provided. Methods for direct-write lithography patterning of such nanocomposite material coatings are also provided. | 12-05-2013 |
20140249526 | STRETCHABLE COMPOSITE CONDUCTORS FOR FLEXIBLE ELECTRONICS, STRETCHABLE PLASMONIC DEVICES, OPTICAL FILTERS, AND IMPLANTABLE DEVICES AND METHODS FOR MANUFACTURE THEREOF - New stretchable electrically conductive composite materials comprising at least one polymer and a plurality of nanoparticles are provided, which exhibit high conductivity even at high strain levels. The composite may comprise polyurethane as the polymer and spherical gold nanoparticles. Such materials have conductivity levels as high as 11,000 Scm | 09-04-2014 |