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Kostenis

Evi Kostenis, Bonn DE

Patent application numberDescriptionPublished
20110104704ASSOCIATION OF EDG5 POLYMORPHISM V286A WITH TYPE II DIABETES MELLITUS AND VENOUS THROMBOSIS/PULMONARY EMBOLISM AND THE USE THEREOF - The present invention relates to a method of identifying an increase in risk for type II Diabetes mellitus, venous thrombosis, or pulmonary embolism in a subject, wherein the presence of an amino acid exchange at position 286 from valine (Val) to alanine (Ala) in the EDG5 protein in a biological sample taken from the subject.05-05-2011

Evi Kostenis, Hoersholm DK

Patent application numberDescriptionPublished
20090099189CRTH2 Receptor Ligands For Medicinal Uses - Compounds of formula (I) are useful for the treatment of disease responsive to modulation of CRTH2 receptor activity, such as asthma, rhinitis, allergic airway syndrome, and allergic rhinobronchitis, wherein A represents a carboxyl group —COON, or a carboxyl bioisostere; A04-16-2009
20090105218CRTH2 Receptor Ligands For Therapeutic Use - Compounds of formula (I) are useful in the treatment of disease responsive to modulation of CRTH2 receptor activity, wherein: A represents a carboxyl group —COOH, or a carboxyl bioisostere; L1 is a bond, —CH04-23-2009

Evi Kostenis, Hoersholm SE

Patent application numberDescriptionPublished
20110269763CRTH2 receptor ligands for medicinal uses - Compounds of formula (I) are useful for the treatment of disease responsive to modulation of CRTH2 receptor activity, such as asthma, rhinitis, allergic airway syndrome, and allergic rhinobronchitis:11-03-2011