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Komatsu, US

Jeffrey M. Komatsu, Renton, WA US

Patent application numberDescriptionPublished
20100041269QUICK-MOUNT RELAY APPARATUS AND METHOD OF INSTALLATION - A relay socket may include an opening for insertion of a relay into the opening, and a plurality of integral locking members for attaching and locking the relay socket to at least one of a structure surface and a relay without the use of attachment hardware.02-18-2010

Li Ni Komatsu, Silver Spring, MD US

Patent application numberDescriptionPublished
20090298868QUINOLINE COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF - A method of identification of quinoline compounds (formula I) that modify melanin synthesis (melanogenesis), and the use of such compounds and compositions thereof to control (e.g., inhibit) melanin production are disclosed.12-03-2009
20090304615TRICYCLIC COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF - A method of identification of tricyclic compounds (formula I) that control melanin synthesis (melanogenesis), and the use of such compounds and compositions thereof to modify (e.g., inhibit) melanin production are disclosed.12-10-2009

Li Ni Komatsu, Clarksville, MD US

Patent application numberDescriptionPublished
20100040568Steroidal compounds as melanogenesis modifiers and uses thereof - Provided are steroidal compounds of formula I, for example, conessine, and the use of such compounds and compositions thereof to modulate (e.g., inhibit) melanogenesis and pigmentation.02-18-2010
20100093823STEROIDAL COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF - A method for the identification of compounds) that control melanin synthesis (melanogenesis), and the preparation and use of such compounds, and compositions and formulations thereof to modify (e.g., inhibit) melanin production are disclosed. A representative compound of the invention is defined by formula I:04-15-2010
20110190229COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING SKIN DARKENING - A method for preventing hyperpigmented skin, undesired pigmentation disorder of skin, or undesired darkening of skin using coumarin compounds, the use of such compounds, and compositions and formulations thereof are disclosed. In a particular embodiment, the coumarin compounds are selected from robustic acid methyl ether, scandenin, and coumophos. The compounds may be prepared as additives to pharmaceutical and cosmetic compositions, and in personal care products such as antiperspirants. In a particular embodiment extends to an antiperspirant product containing a skin darkening inhibitory amount of a compound of the invention. Also, the present skin darkening compounds may be prepared in combination with each other. The compounds, compositions and formulations of the invention may be used for the prevention of the onset or progression of conditions characterized by unwanted skin darkening, including those that may be causally related to aberrant melanogenesis activity including, by way of non-limiting example, hyperpigmentation and others.08-04-2011

Mai Komatsu, Wilmington, DE US

Patent application numberDescriptionPublished
20080201803PLANTS WITH ALTERED ROOT ARCHITECTURE, INVOLVING THE RUM1 GENE, RELATED CONSTRUCTS AND METHODS - Isolated polynucleotides and polypeptides and recombinant DNA constructs particularly useful for altering root structure of plants, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter functional in a plant, wherein said polynucleotide encodes a polypeptide useful for altering plant root architecture.08-21-2008
20090178159PLANTS WITH ALTERED ROOT ARCHITECTURE, INVOLVING THE RUM1 GENE, RELATED CONSTRUCTS AND METHODS - Isolated polynucleotides and polypeptides and recombinant DNA constructs particularly useful for altering root structure of plants, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter functional in a plant, wherein said polynucleotide encodes a polypeptide useful for altering plant root architecture.07-09-2009

Masanobu Komatsu, Orlando, FL US

Patent application numberDescriptionPublished
20090304765R-RAS ACTIVITY IN VASCULAR REGULATION - The invention provides means and methods for vascular regulation through enhancement or inhibition of R-Ras activity. The invention specifically provides means and methods for promoting a quiescent state of a vascular cell by providing additional R-Ras activity to the cell. The invention further provides means and methods for diagnosing a condition of vasculature of an individual.12-10-2009

Stan Komatsu, Laguna Hills, CA US

Patent application numberDescriptionPublished
20110313515REPLACEMENT HEART VALVE - A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve. The valve body has an upstream end and a downstream end, and a diameter at the downstream end is greater than a diameter at the upstream end.12-22-2011

Stanley Komatsu, Laguna Hills, CA US

Patent application numberDescriptionPublished
20110172765Heart Valve Prosthesis and Methods of Manufacture and Use - A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.07-14-2011