Patent application number | Description | Published |
20080255069 | Medicament for Preventive and/or Therapeutic Treatment of Bowel Disease - A medicament for preventive and/or therapeutic treatment of a bowel diseases such as inflammatory bowel diseases including Crohn's disease, which comprises as an active ingredient a retinoid such as, for example, 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid. | 10-16-2008 |
20090118264 | Medicament having neovascularization promoting action - Methods of use of medicaments having neovascularization promoting action, which medicaments comprise a retinoid antagonist such as 4-(5H-7,8,9,10-tetrahydro-5,7,7,10,10-pentamethylbenzo[e]naphtho[2,3-b][1-,4]diazepin-13-yl)benzoic acid as an active ingredient. | 05-07-2009 |
20090118303 | SEROTONIN 5-HT3 RECEPTOR AGONIST - A serotonin 5-HT3 receptor agonist containing a compound represented by the general formula (1) [R | 05-07-2009 |
20090253796 | METHOD FOR TREATING VASCULAR DISEASE - A medicament for prophylactic and/or therapeutic treatment of a vascular disease such as vascular restenosis and/or reocclusion after percutaneous transluminal coronary angioplasty using an intravascular stent, which comprises as an active ingredient a substance selected from the group consisting of retinoids and agents for controlling actions of retinoids such as 4-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid or a salt thereof, or 4-[[[3,5-bis-(trimethylsilyl)phenyl]carbonyl]amino]benzoic acid or a salt thereof, wherein said substance has substantially no antiproliferative action on vascular endothelial cells, but substantially has antiproliferative action on vascular smooth muscle cells. | 10-08-2009 |
20090291492 | METHOD FOR FORMING ORGAN - A method for forming an organ and/or tissue from undifferentiated cells derived from a vertebrate animal in vitro, which comprises the step of culturing the undifferentiated cells derived from a vertebrate animal in the presence of a retinoic acid X receptor ligand (e.g., a retinoic acid X receptor agonist or antagonist), and a method for forming a pancreas from undifferentiated cells derived from a vertebrate animal in vitro or a method for forming a tissue having morphology and function of a pancreas from undifferentiated cells derived from a vertebrate in vitro, which comprises the step of culturing the undifferentiated cells derived from a vertebrate animal in the presence of a retinoic acid receptor ligand, together with activin, that does not substantially bind to the retinoic acid receptor subtype γ. | 11-26-2009 |
20090299059 | Novel Compound Having Heterocyclic Ring - The invention provides a novel oxazolidinone derivative represented by the formula (I): | 12-03-2009 |
20100004203 | MEDICAMENT FOR PREVENTIVE AND/OR THERAPEUTIC TREATMENT OF BOWEL DISEASE - A medicament for preventive and/or therapeutic treatment of a bowel diseases such as inflammatory bowel diseases including Crohn's disease, which comprises as an active ingredient a retinoid such as, for example, 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid. | 01-07-2010 |
20100286427 | RETINOID PRODRUG COMPOUND - A compound represented by the following general formula (I): | 11-11-2010 |
20100324134 | MEDICAMENT FOR PREVENTIVE AND/OR THERAPEUTIC TREATMENT OF BOWEL DISEASE - A medicament for preventive and/or therapeutic treatment of a bowel diseases such as inflammatory bowel diseases including Crohn's disease, which comprises as an active ingredient a retinoid such as, for example, 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid. | 12-23-2010 |
20110071304 | AROMATIC AMIDE DERIVATIVE - A compound represented by the following general formula (I) (R | 03-24-2011 |
20110213156 | 5-MEMBERED HETEROCYCLIC COMPOUND - A compound represented by the following general formula (I): | 09-01-2011 |
20110213157 | TRICYCLIC AMIDE COMPOUND - A compound represented by the following general formula (I): | 09-01-2011 |
20110288299 | TRICYCLIC AMINE COMPOUND - A compound represented by the following general formula (I): | 11-24-2011 |
20120208997 | NOVEL COMPOUND HAVING HETEROCYCLIC RING - The invention provides a novel oxazolidinone derivative represented by the formula (I): | 08-16-2012 |
20120214763 | MEMORY FIXATION ACCELERATOR - A medicament for promoting memory consolidation, which comprises, as an active ingredient, a non-natural retinoid, preferably a retinoid having a basic skeleton comprising an aromatic ring bound with an aromatic carboxylic acid or tropolone by means of a bridging group, more preferably 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid or 4-[(3,5-bis-trimethylsilylphenyl)-carboxamido]benzoic acid. | 08-23-2012 |
20140031575 | SILICON-CONTAINING CARBOXYLIC ACID DERIVATIVE - A compound represented by the formula (I) [R | 01-30-2014 |
20140121407 | DEUTERATED PHENYLPROPIONIC ACID DERIVATIVE - A compound corresponding to 3-[4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]phenyl]propionic acid in which a part or all of hydrogen atoms in the ethylene group constituting the propionic acid moiety are replaced with deuterium atoms, a salt thereof, or an ester thereof, and a prodrug for releasing Am80 as an active medicament after being absorbed into a living body, which comprises the aforementioned compound, a salt thereof, or an ester thereof as an active ingredient. | 05-01-2014 |