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Kohl

Andreas Kohl, Stockholm SE

Patent application numberDescriptionPublished
20100216113Methods - A method for selecting or designing a compound expected to modulate the activity of Leukotriene C4 synthase (LTC4S), the method comprising the step of using molecular modelling means to select or design a compound that is predicted to interact with the catalytic site or a substrate binding region of LTC4S, wherein a three-dimensional structure of at least a part of the catalytic site or a substrate binding region of LTC4S is compared with a three-dimensional structure of a compound, and a compound that is predicted to interact with the said catalytic site or substrate binding region is selected. The selected compound may be predicted to bind to at least a part of a region of the structure termed the “GSH substrate binding cavity” (formed by residues including residues Arg51, Arg30, Arg104, Gln53, Asn55, Glu58, Tyr59, Tyr93, Tyr97, Ile27, Pro37, Leu108 of full length human LTC4S, or equivalent residues); the “lipophilic substrate binding crevice” (formed by residues including Ala20, Leu24, Ile27, Tyr59, Trp116, Ala112, Leu115, Leu108, Tyr109, Leu62, Val119, Thr66, Vall6 and Leu17, or equivalent residues); or the “catalytic site” (formed by residues including Arg104 or Arg31, or equivalent residues).08-26-2010

Christopher Kohl, Bonaduz CH

Patent application numberDescriptionPublished
20100298470PROCESS FOR CONTINUOUSLY PREPARING AN ORGANOPHOSPHORUS COMPOUND AND USE THEREOF - The present invention relates to the production of organophosphorus compounds, in particular 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) or derivatives thereof which have been known for many years in prior art. They are used preferably as additives for polymers. In particular the use of DOPO and derivatives thereof as flame retardants for polymers, such as e.g. polyesters, polyamides, epoxy resins, has proved to be advantageous.11-25-2010

Oliver Kohl, New South Wales AU

Patent application numberDescriptionPublished
20100212247BLOCK WALL SYSTEM - A block wall system including a block wall having a multiplicity of courses of blocks; at least one longitudinal reinforcement bar that extends through the block wall; and at least one bracket for locating the longitudinal reinforcement bar; wherein the longitudinal reinforcement bar passes through the void of at least one block in the block wall and through a capture zone of the bracket located within the block wall.08-26-2010

Petra Kohl, Vienna AT

Patent application numberDescriptionPublished
20100034812Antibodies Specific for BET V1 and Use Thereof in the Prevention and Treatment of BET V1- Induced Diseases - The present invention relates to Bet V 1 specific antibodies or fragments thereof and their use in the prevention and treatment of allergen induced diseases, wherein the antibodies block the binding of IgE to Bet V 1.02-11-2010

Sandro Kohl, Bern CH

Patent application numberDescriptionPublished
20120130492IMPLANTABLE SYSTEM HAVING A DISSOLUTION MECHANISM UPON RECOVERY - The invention relates to a system for controlled loading of a reconstructed human or animal tissue during the healing phase, comprising an anchor element (05-24-2012

Winfried Kohl, Garden View ZA

Patent application numberDescriptionPublished
20090139639Method of Producing a Sheet - A method of producing a plastic sheet equipped with electrical conductors is disclosed. The method that enables automatic production includes (a) fixing in a frame an electrically conducting wire in a sinusoidal, square wave pattern and in a single plane, (b) bringing into contact the single plane and a surface of a plastic sheet under conditions calculated to bond the plastic to said conductor, and (c) removing the frame.06-04-2009