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Knowles, GB

Andrew Knowles, Lancashire GB

Patent application numberDescriptionPublished
20100119188BEARINGS - A bearing structure, for example of a needle roller bearing, has an outer surface defined in part by a composition comprising a first polymeric material having a Rockwell hardness (m scale) in the range 80 to 130. Preferred materials are polyaryletherketones, for example polyetheretherketone.05-13-2010

Andrew Knowles, Southampton GB

Patent application numberDescriptionPublished
20100158260DYNAMIC AUDIO MODE SWITCHING - In one embodiment, a method and apparatus for processing an audio signal are provided. In one example of the invention, an audio signal is received. The audio signal is classified as a high quality signal or a low quality signal based upon a determination of the bandwidth, signal source, and/or signal type of the audio signal. The audio signal is further processed responsive to whether the audio signal is classified as a high quality signal or a low quality signal.06-24-2010

Anthony Knowles, Hampshire GB

Patent application numberDescriptionPublished
20100023316PARTICIPANT RESPONSE SYSTEM AND METHOD - A participant response system comprises a plurality of handsets for allowing a participant of an event to input a response. Each handset comprises a wireless handset having a keyboard for allowing a user to input a response. The handsets are configurable either as a participant response handset to allow a participant to enter a response, or as a base station. The handset also includes audio capability to allow participants to receive and input audio01-28-2010

Anthony M. Knowles, Hampshire GB

Patent application numberDescriptionPublished
20090138343Voting System - An apparatus is disclosed for conducting a ballot in which at least one vote is cast by a voting input device (05-28-2009

Christopher John Knowles, Woodstock GB

Patent application numberDescriptionPublished
20090178932CONTROL OF BIOCATALYSIS REACTIONS - A process for increasing the rate of biocatalysis reactions, which comprises applying a direct current electric field to a reaction mixture, wherein the reaction mixture and the electrodes used to apply said electric field are separated such that the reaction mixture does not come into contact with said electrodes.07-16-2009

Grahame Knowles, Lincoln GB

Patent application numberDescriptionPublished
20090133759Hydraulic restrictor - A hydraulic restrictor comprising: a passage along which hydraulic fluid flows; a member which extends along said passage, said member restricting the flow along the passage; and means for selectively securing said member at a plurality of different positions along the passage thereby to enable variation in the restriction on flow along the passage, said securing means securing said member at each said position by securing the member against the side wall of the passage.05-28-2009
20100200344Apparatus for damping the torsional excitation of a hollow drive shaft - An apparatus for damping the torsional excitation of a hollow drive shaft is provided. The apparatus includes an elongate member that extends along the interior of the drive shaft, one end of the member is secured to one end of the drive shaft, the other end of the member is disposed at the other end of the drive shaft, and a hydraulic damping device secured to the other end of the drive shaft for damping vibration of the other end of the member. The hydraulic damping device includes a piston and cylinder arrangement having first and second hydraulic chambers, a reservoir of hydraulic fluids, and hydraulic circuitry which uses the hydraulic chambers to communicate with the reservoir. The hydraulic damping device is arranged so that any leakage of hydraulic fluid from the first and second hydraulic chambers via a piston/cylinder interface passes to the reservoir of hydraulic fluid.08-12-2010
20100326784TORQUE PROTECTION DEVICE AND TORQUE TRANSMISSION ASSEMBLY - A torque protection device is provided which includes an axial direction and a radial direction. The torque protection device further includes a driven element for connecting the torque protection device to a driven output member, a driving element for connecting the torque protection device to a driving input member, and at least one shear pin connecting the driving element to the driven element. The shear pin includes a first end held by the driven element and a second end held by the driving element. The shear pin extends from the driven element to the driving element in the radial direction of the torque protection device.12-30-2010
20120094776APPARATUS COMPRISING A SHAFT AND A BALANCING SLEEVE - An apparatus including a shaft mounted for rotation and a balancing sleeve is provided. The balancing sleeve functions to balance the shaft during rotation and includes first and second ends. The first end is secured to the shaft so that the balancing sleeve is substantially concentric with the shaft and rotates with the shaft. The second end incorporates balancing weight to balance the shaft at lower speeds of rotation of the shaft where there is substantially no flexing of the shaft. The lengthwise stiffness of the balancing sleeve is matched to the lengthwise stiffness of the shaft to maintain balance of the shaft at higher speeds of rotation of the shaft where there is flexing of the shaft.04-19-2012

Patent applications by Grahame Knowles, Lincoln GB

Ian Knowles, Burnham GB

Patent application numberDescriptionPublished
20110286554RF receivers - A method and apparatus are provided for receiving an RF service. At least two RF channels 11-24-2011

Ian Knowles, London GB

Patent application numberDescriptionPublished
20110024225SOUND SHELL - A performance shell for outdoor music performance comprises a platform providing a performance area for receiving at least one sound source, the platform combining unitarily with a rear wall reflectors, side wall reflector and a canopy reflector to define an enclosure having a front opening for communicating acoustically with an open air audience area. The canopy reflector comprises a main portion extending above the performance area and a projecting portion projecting forwardly of a front edge of the performance area, the canopy reflector further comprising sound diffusion formations on an underside of the main portion and the projecting portion and adapted to provide non-specular reflection of sound from the at least one sound source for enhancing sound received both in the performance area and the audience area.02-03-2011

Ian Robert Knowles, Buckinghamshire GB

Patent application numberDescriptionPublished
20110187657Touch sensitive screen for scrolling through sets of data - A touch sensitive screen system is provided for strolling through a set of data displayed on the screen. A plurality of touch sensitive areas (A, B, C, D, E) are provided. Contact movement with a central area (A) commences scrolling of data displayed on the screen. Movement of the contact into one of a plurality of edge portions (B, C, D, E) causes scrolling of the data to continue.08-04-2011

James Knowles, Culcheth GB

Patent application numberDescriptionPublished
20090071254METHOD AND APPARATUS FOR THE DETECTION OF CRACKS IN THE TEETH OF GENERATOR ROTORS - A method for non-destructive testing the teeth of a high power electrical generator rotor includes the steps of: providing a plurality of ultrasonic pulse echo transducers (03-19-2009

John Bruce Knowles, Dorset GB

Patent application numberDescriptionPublished
20110041716WORKPIECE PROCESSING SYSTEM AND METHOD - A workpiece processing system and method, the workpiece processing system comprising at least one workpiece processing module (02-24-2011

Jonathan Knowles, Madingley GB

Patent application numberDescriptionPublished
20110138147DYNAMIC REALLOCATION OF PHYSICAL MEMORY RESPONSIVE TO VIRTUAL MACHINE EVENTS - Described are methods and systems for dynamically reallocating memory amongst virtual machines executing within a virtualization environment. A computer can execute a virtualization environment that can include one or more virtual machines and that can include a memory manager. The memory manager can dynamically reallocate memory by identifying a maximum and minimum memory value for each virtual machine, determining a target memory value for each virtual machine using the maximum and minimum memory value, and identifying one or more virtual machines that have an actual memory usage value that is less than the target memory value calculated for those virtual machines. To re-allocate the memory, the memory manager can allocate additional memory to the identified virtual machines by inflating a balloon driver, then de-allocate the additional memory, and reallocate the de-allocated, additional memory to other virtual machines within the virtualization environment.06-09-2011

Linda K. Knowles, Midlothian GB

Patent application numberDescriptionPublished
20100041565BLOOD TYPING - A blood testing method for use in the detection of a disease, wherein at least one characteristic antibody or complement factor is bound to a subject's red blood cells, comprises providing a microarray wherein a plurality of binding agents therefor are immobilised on a substrate at discrete pre-defined positions; and contacting a blood sample therewith. The presence of bound red blood cells is then detected.02-18-2010

Michael Knowles, Cambridge GB

Patent application numberDescriptionPublished
20080299637Production of Conjugates - A method of reacting a first chemical entity and a second chemical entity to form a conjugate in which the first and second chemical entities are covalently bound with respect to each other, comprises bringing into simultaneous contact the first chemical entity, the second chemical entity and a thiol generator, wherein the thiol generator reacts with the first chemical entity in a thiolation reaction resulting in formation of a free sulfhydryl group on the first chemical entity, and the free sulfhydryl group reacts with the second chemical entity to form the conjugate, and wherein the second chemical entity is polyvalent with respect to its reactivity with sulfhydryl groups. The present invention primarily differs from the prior art in that no separation step is involved between reaction of the thiol generator and first chemical entity and reaction with the second chemical entity. The invention also provides a conjugation kit.12-04-2008

Nick Knowles, Berkshire GB

Patent application numberDescriptionPublished
20110311568Vaccine - The present invention provides a foot and mouth disease (FMD) vaccine comprising or capable of expressing afoot and mouth disease virus (FMDV) VP1 polypeptide having a deletion of at least seven amino acids in the G-H loop such that the VP1 polypeptide lacks an RGD motif. The present invention also provides a method for preventing and/or treating FMD in a subject which comprises the step of administration of such a vaccine.12-22-2011

Nigel Knowles, London GB

Patent application numberDescriptionPublished
20090138413Method And Systems Of Structuring A Derivative Financial Instrument - The invention provides methods of extrapolating at least one future mortality rate by calculating a current year mortality rate for a particular age cohort, and applying a series of improvement factors to the current year mortality rate. The invention further provides methods of structuring a derivative financial instrument by providing projected going-forward mortality rates reflective of a degree of improvement in mortality rate experience for particular age cohorts for a particular future period, and defining settlement parameters wherein a value recognized by an investor in said instrument at the time of settlement relates at least in part to the correlation between said projected mortality rate and actually-incurred mortality rate for the age cohort during at least a portion of the period.05-28-2009
20090271334SYSTEM AND METHOD FOR PROVIDING MORTALITY RATE INFORMATION AND EMPLOYING IT FOR STRUCTURING AND ANALYSIS OF FINANCIAL INSTRUMENTS - The invention provides methods of extrapolating at least one future mortality rate by calculating a current year mortality rate for a particular age cohort, and applying a series of improvement factors to the current year mortality rate. The invention further provides methods of structuring a derivative financial instrument by providing projected going-forward mortality rates reflective of a degree of improvement in mortality rate experience for particular age cohorts for a particular future period, and defining settlement parameters wherein a value recognized by an investor in said instrument at the time of settlement relates at least in part to the correlation between said projected mortality rate and actually-incurred mortality rate for the age cohort during at least a portion of the period.10-29-2009

Paul Knowles, Manchester GB

Patent application numberDescriptionPublished
20110265084CROSS ARCHITECTURE VIRTUAL MACHINE MIGRATION - A system, method and computer program for transferring a running virtual machine from a first to a second physical machine, where each of the physical machines has a different instruction set architecture. The system may comprise a receiver for receiving a transfer request; responsive to receiving the transfer request, means for pausing the virtual machine; and means for collecting a state of the virtual machine. The system may include means for stopping a first interface component operable on the first physical machine; means for starting a second interface component operable on the second physical machine; and means for transferring the state to the second interface component. The system may further comprise means for starting the virtual machine on the second physical machine in response to the state transfer.10-27-2011

Paul Thomas Knowles, Manchester GB

Patent application numberDescriptionPublished
20080263342Apparatus and method for handling exception signals in a computing system - Described is method and apparatus for handling exception signals in combination particularly with the dynamic conversion of binary code executable by a one computing platform into binary code executed instead by another computing platform. An exception handling unit selectively handles some exception signals with respect to a target state and handles others with respect to a subject state derived from the target state. Signal handling sub-units are arranged to process the exception signal with respect to the target state and output a request either to return to execution or to pass on the exception signal. A delivery path selection unit is arranged to determine a delivery path of the exception signal to a selected group of the plurality of signal handling sub-units. A signal control unit is arranged to deliver the exception signal in turn to each of the selected group of signal handling sub-units.10-23-2008

Peter Knowles, Southampton GB

Patent application numberDescriptionPublished
20110101483TWO COLOUR PHOTON DETECTOR - A two-colour radiation detector (05-05-2011

Peter Knowles, Hampshire GB

Patent application numberDescriptionPublished
20100252736IMAGING SYSTEM - An imaging system is described which includes a radiation source outputting radiation incident on a scene. The radiation is pulsed and the reflected radiation is detected by a detector array and a resulting signal output by a read out circuit. The signal output is characteristic of the scene on which the radiation is incident. The output signal is combined over a number of pulses, the averaging being carried out on-chip and within the detector circuitry. The radiation source may be a semiconductor diode source amplified with a doped fibre amplifier.10-07-2010

Peter Knowles, Essex GB

Patent application numberDescriptionPublished
20110315881IR CAMERA SYSTEM AND METHOD - An Infra Red (IR) camera and method of operating the same is disclosed. The camera includes a detector having an infrared focal plane array (IRFPA). The camera is operated in such a fashion, implemented in software, to maximise the detector operating temperature under varying scene temperature and atmospheric conditions in order to achieve a predetermined and adequate level of sensitivity and operability from the detector.12-29-2011

Phil Knowles, Cumbria GB

Patent application numberDescriptionPublished
20120122982USE OF PUFAS TO TREAT NERVE DAMAGE - The present invention provides use of compounds which are polyunsaturated fatty acid (PUFA) derivatives of formula (I), in the form of racemates, stereoisomers or mixtures of stereoisomers, or pharmaceutically acceptable salts, or solvates thereof, wherein -AIk- is —(CH05-17-2012

Reginald Knowles, Nottinghamshire GB

Patent application numberDescriptionPublished
20110094843DRIVE ENGAGEMENT APPARATUS - Drive engagement apparatus for engaging a driven gear (04-28-2011

Rodney P. Knowles, Lancashire GB

Patent application numberDescriptionPublished
20100233422Method, Coating Latex and Reinforcing Cord for Forming a Rubber Article by Extrusion or Moulding - A method for forming rubber articles, containing reinforcing strands, by extrusion or moulding, involves coating the reinforcing strands with a coating latex and drying the latex such that it remains uncured until the article containing the coated reinforcing strands is moulded or extruded. Improved adhesion between rubber matrix and reinforcing strands is obtained, particularly for filled rubber and EPDM rubber. Preferred coating latices and coated reinforcing cords for use with the method are also disclosed, the coating comprising a metal oxide, a maleimide crosslinking agent, a nitroso-compound, and halogenated rubber.09-16-2010

Simon Knowles, Bath GB

Patent application numberDescriptionPublished
20110078416APPARATUS AND METHOD FOR CONTROL PROCESSING IN DUAL PATH PROCESSOR - A computer processor comprises a decode unit and a processing channel. The decode unit decodes a stream of instruction packets from a memory, each instruction packet comprising a plurality of instructions. The processing channel comprises a plurality of functional units and operable to perform control processing operations. The decode unit is operable to receive and decode instruction packets of a bit length of 64 bits and to detect if the instruction packet defines three control instructions each having a length of 21 bits. The decode unit detects that the instruction packet comprises the three control instructions. The control instructions are supplied to the processing channel for execution in the order in which they appear in the instruction packet. The detection uses an identification bit in the instruction packet.03-31-2011
20110161640APPARATUS AND METHOD FOR CONFIGURABLE PROCESSING - A configurable execution unit comprises operators capable of being dynamically configured by an instruction at the level of processing multi-bit operand values. The unit comprises one or more dynamically configurable operator modules, the or each module being connectable to receive input operands indicated in an instruction, and a programmable lookup table connectable to receive dynamic configuration information determined from an opcode portion of the instruction and capable of generating operator configuration settings defining an aspect of the function or behavior of a configurable operator module, responsive to the dynamic configuration information in the instruction.06-30-2011

Patent applications by Simon Knowles, Bath GB

Toby Grahame Knowles, Glastonbury GB

Patent application numberDescriptionPublished
20090326410Method of Detecting and Predicting Ovulation and the Period of Fertility - A method of providing information relating to the fertility of a female mammal comprising the steps of: (i) taking multiple temperature readings from the female mammal during an extended period; (ii) identifying and disregarding temperature readings having one or more characteristics of irrelevant or faulty data; (iii) obtaining one or several representative temperature values for the extended period; (iv) repeating steps (i) to (iii) over multiple extended periods; (v) analysing the representative temperature values obtained over multiple extended periods for one or more patterns in the representative temperature values indicative or predictive of ovulation in order to provide information relating to the fertility of the female mammal to a user, wherein the representative temperature values are not the maximum or minimum temperature readings obtained for the extended period; and related uses and apparatus.12-31-2009

Tuomas Knowles, Cambridgeshire GB

Patent application numberDescriptionPublished
20090203535ACOUSTIC WAVE TRANSDUCER SUBSTRATE AND MEASUREMENTS USING THE SAME - An acoustic wave transducer substrate is provided, the substrate having a surface with a plurality of growth promotion sites for promoting the accumulation of polypeptide molecules at said sites. The growth-promotion sites are preferably for promoting fibril formation. The invention also provides a method of screening a candidate compound for an effect on fibril growth, including the steps of: providing an acoustic wave transducer substrate having a surface with a plurality of growth promotion sites for promoting the accumulation of polypeptide molecules at said sites; causing oscillation of the substrate; contacting the substrate surface with a sample fluid comprising polypeptide molecules and a candidate compound; and measuring one or more parameters of the substrate oscillation to monitor the accumulation of said polypeptide molecules of interest in the presence and absence of said candidate compound. Alteration of the accumulation of said polypeptide molecules of interest in the presence of said candidate compound as compared with that in the absence of said candidate compound indicates that the candidate compound has an effect of fibril growth.08-13-2009