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Klunder, NL

Derk J.w Klunder, Geldrop NL

Patent application numberDescriptionPublished
20090001284Biosensor with One-Dimensional Sub-Diffraction-Limited Apertures Composed of a Grid and a Polarizer - A method and sensor for the detection of luminescence radiation generated by at least one luminophore is disclosed. In the context of the present invention the biosensor comprises a grid (01-01-2009

Derk J.w. Klunder, Eindhoven NL

Patent application numberDescriptionPublished
20100001210APERTURE BIOSENSOR WITH TRENCHES - A luminescence sensor, comprising a non-transparent substrate structure (01-07-2010
20100044585BIOSENSOR USING WIRE-GRIDS FOR INCREASING CAVITY ENERGY - The invention discloses a luminescence sensor (02-25-2010
20100072397SUB WAVELENGTH APERTURE - There is provided a method of detecting a presence of a luminophore in a detection volume comprising providing excitation radiation in said detection volume. A luminophore is provided in said detection volume being excitable by said excitation radiation. The luminescent radiation is detected to identify the presence of said luminophore in said detection volume. In one aspect of the invention, said luminophore is selected to emit luminescent radiation having a wavelength in said medium that is larger than twice said smallest dimension; and wherein said luminophore is selected to be excitable by excitation radiation having a wavelength in said medium that is smaller than twice said smallest dimension. Accordingly, luminescent radiation is blocked from entering the detector but for the portion present on an interface of the aperture.03-25-2010
20100096562WIREGRID WAVEGUIDE - There is provided a wave guide comprising: a wave guiding medium, having an index of refraction and provided between first and second wave propagating planar structures at least said first planar structure comprises a plurality of slitted-apertures defining a length axis of the first reflective structure; the slitted apertures constructed and arranged to reflect a R-polarized component of said radiation oriented parallel to said length axis; and wherein said first planar structure is arranged between said wave guiding medium and an adjacent medium having an index of refraction equal or larger than the wave guiding medium. In one aspect of the invention, a waveguide is proposed to limit an excitation region wherein luminophores are excited; substantially independent from the surrounding media of the waveguide. Preferentially, the waveguide is used in a luminescence sensor.04-22-2010
20100108908WIREGRID MONITOR DEVICE - A device for monitoring radiation emitted by luminophores present in an analyte fluid of a wiregrid biosensor. The monitoring device comprises a non-polarized light source (05-06-2010
20100276577MICROELECTRONIC SENSOR DEVICE - The invention concerns an optical device for providing evanescent radiation, in response to incident radiation, in a detection volume for containing a target component in a medium, the detection volume having at least one in-plane dimension (W11-04-2010

Derk J. W. Klunder, Eindhoven NL

Patent application numberDescriptionPublished
20110039720DEVICE AND METHOD FOR PARALLEL QUANTITATIVE ANALYSIS OF MULTIPLE NUCLEIC ACIDS - The present invention relates to a process for conducting real-time PCR, and to a device for conducting the method of the present invention. The invention is especially suited for the simultaneous identification and quantification of nucleic acids present in a sample, e.g. a biological sample. Further, this invention describes a method for simultaneous quantitative analysis of multiple nucleic acid sequences in a single compartment by using an integrated nucleic acid microarray combined with a highly surface-specific readout device. The invention relates to a device wherein a surface which is either part of the chamber surface or a surface that is created in the reaction chamber, such as bead surface, is coated with capture probes and in the same chamber, a PCR reaction takes place.02-17-2011