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Kleinberg, US
Andrew Kleinberg, East Meadow, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090197864 | Furo- and Thieno [3,2-c] Pyridines - Furo[3,2-c]Pyridine and Thieno[3,2-c]pyridine compounds of Formula I, and pharmaceutically acceptable salts thereof, preparation, intermediates, pharmaceutical compositions, and use, such as in disease treatment, including cancers, including conditions in which EMT is involved, including conditions mediated by protein kinase activity such as RON and/or MET. | 08-06-2009 |
| 20090286768 | SUBSTITUTED IMIDAZOPYR- AND IMIDAZOTRI-AZINES - Fused pyridine-based bicyclic compounds having the structure of Formula I, as defined herein, pharmaceutically acceptable salts thereof, preparation, compositions, and disease treatment therewith. This abstract does not define or limit the invention. | 11-19-2009 |
David Kleinberg, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110034381 | Methods for Therapeutic Treatment of Benign Prostatic Hypertrophy (BPH) - Therapeutic methods for treatment of benign prostatic hypertrophy by inhibition of the activity of insulin-like growth factor-I (IGF-I). Methods encompass the use of IGF-I antagonists, as well as the use of compounds that lower the effective level of IGF-I or interfere with post receptor effects of IGF-I action in the prostate. | 02-10-2011 |
David L. Kleinberg, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090325863 | Somatostatin analogs and IGF-I inhibition for breast cancer prevention - The present invention relates generally to the use and application of compounds or agents, including somatostatin analogs, with effect on, affinity for, or specificity to SSTR3 and/or SSTR5 somatostatin receptors, particularly in the breast, for the treatment of breast hyperplasia, pre-neoplastic lesions and breast carcinoma and/or prevention or reduction of risk for breast cancer or treatment of breast cancer, including DCIS. The invention also relates to use of somatostatin analog SOM230 in treatment of breast hyperplasia and/or prevention or treatment of breast cancer. The invention includes assays and methods for screening and identifying breast hyperplasia with elevated SSTR3 and/or SSTR5 receptors and for chemotherapy and identifying compounds of use in the invention which are specific for, modulate via, or bind to SSTR3 and/or SSTR5 receptors. | 12-31-2009 |
Hershel Kleinberg, Alexandria, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20110047385 | Methods and Systems for Digitally Signing a Document - Methods and systems according to various embodiments provide a voice-based digital signature to a digital document. For example, a user can access a website to fill in or compete a digital document such as an insurance application (e.g., an application for Medicare supplement insurance), and can call an interactive voice response (“IVR”) system to provide a voice-based (or oral or aural) digital signature to the digital document. The digital signature can then be attached, related, or appended to that digital document in place of a traditional signature. Thus, the digital document need not be printed and sent to the user for a signature. | 02-24-2011 |
Israel Kleinberg, Smithtown, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080233054 | DENTAL ANTI-HYPERSENSITIVITY COMPOSITION AND METHOD - The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion. | 09-25-2008 |
| 20110111361 | Device For The Detection Of Non-Cavitated Early Dental Caries Lesions - The invention provides a device for detecting non-cavitated caries lesions, including a measuring electrode having an electrically conductive tip. The tip is dimensionally configured to fit within a fissure and provide electrical contact with a patient's tooth. A reference electrode is also included, the reference electrode being configured for electrical contact with the patient's body. A measuring means is also provided for determining electrical conductance between the measuring electrode and the reference electrode, wherein the device is further configured to receive a current source for providing electrical current between the measuring electrode and the reference electrode. | 05-12-2011 |
Robert Kleinberg, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100250742 | Global load balancing across mirrored data centers - An intelligent traffic redirection system that performs global load balancing can be used in any situation where an end-user requires access to a replicated resource. The method directs end-users to the appropriate replica so that the route to the replica is good from a network standpoint and the replica is not overloaded. The technique preferably uses a Domain Name Service (DNS) to provide IP addresses for the appropriate replica. The most common use is to direct traffic to a mirrored web site. | 09-30-2010 |
Robert Kleinberg, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080204013 | LOGGING METHOD FOR DETERMINING CHARACTERISTIC OF FLUID IN A DOWNHOLE MEASUREMENT REGION - For use in logging downhole in an earth borehole, a method for determining a characteristic of oil that may be present in a downhole measurement region, includes the following steps: providing a plurality of crude oil samples; determining the viscosities of the crude oil samples; performing test measurements, using a predetermined operating mode, on media including the crude oil samples to obtain test data; applying a test processing procedure to the test data to obtain an output test parameter relating to the test data and the predetermined operating mode; deriving, for the plurality of crude oil samples, a correlation relating the output test parameter to the viscosities of the crude oil samples; performing downhole measurements in the measurement region with a logging device, operated with substantially the predetermined operating mode, to obtain logging data, and applying a measurement processing procedure to the logging data to obtain an output logging parameter; and determining the oil characteristic using the output logging parameter and the correlation. | 08-28-2008 |
Robert D. Kleinberg, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100217801 | Network performance monitoring in a content delivery system - A method for Internet content delivery in a content delivery network established at network locations, the content delivery network comprising a plurality of content servers for serving content resources. The plurality of content servers includes a plurality of subsets of content servers, each subject being located at one of a plurality of Internet data centers. For each Internet Protocol (IP) address block from which requests for content resources are expected to be received, the method generates a candidate list of Internet data centers to be used to service the requests for content resources. For the IP address block, the method selects at least one of the Internet data centers from the candidate list to be used to service the requests for content resources. The selected Internet data center for the IP address block is written into a network map. The selecting step is carried out concurrently for each IP address block from which requests for content resources are expected to be received such that the network map comprises the selected Internet data center for each IP address block. The network map is then provided to a domain name service (DNS) associated with the content delivery network. In response to a DNS query received at the domain name service associated with the content delivery network, the network map is used to identify one of the Internet data centers from the candidate list to be used to service a request for a content resource. | 08-26-2010 |
Robert D. Kleinberg, Ithaca, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100070420 | ONLINE PRICING AND BUYBACK - A seller may sell advertisements, such as banner ads, to a buyer pursuant to a request made by the buyer to the seller. Each request has a value. The seller may accept the request from the buyer to provide a banner ad for the buyer at a later time. A request, once accepted, may be revoked at a cost which may be a fixed fraction of the request value. The cost may be referred to as a buyback cost. The buyback cost represents the cost of revoking a request that had been accepted. Additionally, matroid set systems and knapsack systems may use buyback techniques. | 03-18-2010 |
Robert L. Kleinberg, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090091320 | Methods and Apparatus for Monitoring a Property of a Formation Fluid - Methods and apparatus for the characterization of formation fluids are disclosed. A downhole tool disposed in a borehole penetrating a subterranean formation obtains a NMR measurement, effects a change in a characteristic of the formation fluid, and obtains another NMR measurement subsequent to the change. Alternatively, the downhole tool effects a radial gradient of a characteristic of the formation and obtains NMR measurements at two or more selected radial distances from the wellbore wall. A parameter representative of the subterranean formation or the formation fluid is further determined from the NMR measurements. | 04-09-2009 |
Robert Leonard Kleinberg, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090158820 | METHOD AND SYSTEM FOR DOWNHOLE ANALYSIS - Advanced remote self-contained chromatographic systems and techniques for analyzing a mixture comprising components having a wide range of boiling points. The chromatographic systems and techniques can utilize components and techniques that allow staged, simultaneous, and/or sequential vaporization of an analyte to facilitate rapid analysis. The chromatographic systems and techniques can also utilize components and techniques that focus eluents from a first separation stage prior to reduce characterization time in subsequent stages. | 06-25-2009 |
Rochelle Kleinberg, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110152987 | PLACEMENT DEVICES THAT ENABLE PATIENTS TO ACCURATELY POSITION MEDICAL PATCHES AT TARGET LOCATIONS AND METHODS THEREFOR - A placement device for a medical patch includes an alignment guide having a shaft with a first end having a first anatomical alignment marker and a second end having a second anatomical alignment marker, a swinging gate both pivotally and rotationally coupled with the first end of the shaft for selectively pivoting the gate toward and away from the shaft and rotating the gate between opposite sides of the shaft, whereby the gate has first and second major faces and a first opening extending through the gate between the first and second major faces. The placement device includes a spacer for selectively adjusting spacing between the gate and the first end of the shaft, and a flexible diaphragm having a flexible dome disposed within the first gate opening. At least one magnet is located in the center of the flexible dome for holding the medical patch within the flexible dome. | 06-23-2011 |
Samantha Kleinberg, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090006460 | METHOD, SYSTEM, COMPUTER-ACCESSIBLE MEDIUM AND SOFTWARE ARRANGEMENT FOR ORGANIZATION AND ANALYSIS OF MULTIPLE SETS OF DATA - According to exemplary embodiments of the present invention, system, computer-accessible medium and method of organizing or analyzing at least two sets of data can be provided. For example, at least two sets of data may be organized or analyzed by generating a data structure for the at least two sets of the data and comparing the data structure for the at least two sets of the data. The data structure may be in the form of a phylogenetic-type tree. | 01-01-2009 |
| 20110167031 | METHOD, SYSTEM, AND COMPUTER-ACCESSIBLE MEDIUM FOR INFERRING AND/OR DETERMINING CAUSATION IN TIME COURSE DATA WITH TEMPORAL LOGIC - Time-course data with an underlying causal structure may appear in a variety of domains, including, e.g., neural spike trains, stock price movements, and gene expression levels. Provided and described herein are methods, procedures, systems, and computer-accessible medium for inferring and/or determining causation in time course data based on temporal logic and algorithms for model checking. For example, according to one exemplary embodiment, the exemplary method can include receiving data associated with particular causal relationships, for each causal relationship, determining average characteristics associated with cause and effects of the causal relationships, and identifying the causal relationships that meet predetermined requirement(s) as a function of the average characteristics so as to generate a causal relationship. The exemplary characteristics associated with cause and effects of the causal relationships can include an associated average difference that a cause can make to an effect in relation to each other cause of that effect. | 07-07-2011 |