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Klein, IL

Cheri E. Klein, Northbrook, IL US

Patent application numberDescriptionPublished
20110166171SUSTAINED RELEASE MONOEXIMIC FORMULATIONS OF OPIOID AND NONOPIOID ANALGESICS - The present invention relates to monoeximic solid dosage forms for administering pharmaceutical agents, particularly Hydrocodone and acetaminophen, methods for preparing said dosage forms, and methods for providing therapeutic agents to patients in need of treatment.07-07-2011

Cheri Enders Klein, Northbrook, IL US

Patent application numberDescriptionPublished
20100221293CONTROLLED RELEASE FORMULATIONS OF OPIOID AND NONOPIOID ANALGESICS - Sustained release dosage forms for twice daily oral dosing to a human patient for providing relief from pain are provided. The sustained release dosage form comprises an immediate release component and a sustained release component, wherein the immediate release component and the sustained release component collectively contain a therapeutically effective amount of an opioid analgesic and a therapeutically effective amount of nonopioid analgesic. In a preferred embodiment, the nonopioid analgesic is acetaminophen and the opioid analgesic is hydrocodone and pharmaceutically acceptable salts thereof, and in preferred embodiments, the pharmaceutically acceptable salt is bitartrate. The dosage forms produce plasma profiles in a patient characterized by a Cmax for hydrocodone of between about 0.6 ng/mL/mg to about 1.4 ng/mL/mg and an AUC for hydrocodone of between about 9.1 ng*hr/mL/mg to about 19.9 ng*hr/mL/mg (per mg hydrocodone bitartrate administered) and a Cmax for acetaminophen of between about 2.8 ng/mL/mg and 7.9 ng/mL/mg and an AUC for acetaminophen of between about 28.6 ng*hr/mL/mg and about 59.1 ng*hr/mL/mg (per mg acetaminophen administered) after a single dose.09-02-2010

Patent applications by Cheri Enders Klein, Northbrook, IL US

Daniel Klein, Shiloh, IL US

Patent application numberDescriptionPublished
20080221006Biodegradable alkaline disinfectant cleaner with analyzable surfactant - An aqueous, alkaline cleaning composition for use on hard-to-clean soils, encountered in pharmaceutical, personal care, food and cosmetic manufacturing, comprising a source of alkalinity, a biodegradable surfactant system further comprising one or more surfactants, one or more hydrotropes, and a UV-analyzable surfactant, and a biodegradable chelating agent. The composition offers unique advantages of stability over the expected shelf life, low-foaming property, phosphate-free and biodegradable components, and unexpectedly enhanced antimicrobial, including virucidal, activity in one cleaning composition. The UV-analyzable surfactant allows for validation of cleaning processes using known techniques for manufacturers who are required or desire to do so.09-11-2008

Daniel A. Klein, Shiloh, IL US

Patent application numberDescriptionPublished
20100196503Low odor, hard surface sporicide - A low odor, liquid disinfectant composition comprising multiple components, which, upon mixing, provide an aqueous solution comprising low levels of peracetic acid for use in decontaminating articles and surfaces contaminated with bacteria, viruses, fungi and other biological contaminants such as spores, including, but not limited to, 08-05-2010

Patent applications by Daniel A. Klein, Shiloh, IL US

David T. Klein, Alsip, IL US

Patent application numberDescriptionPublished
20080236857METHOD AND SYSTEM FOR PREVENTING INTRUSION OF POURED CONCRETE IN AN ELECTRICAL OR TELECOMMUNICATIONS BOX - The present invention is directed to a method and system for preventing intrusion of viscous poured concrete into electrical or telecom boxes using resilient members having a top surface that fills the surface opening of the box it is inserted into where the spring back of the resilient member insures a proper seal around the surface opening. An example method for preventing intrusion of poured concrete into a box comprises selecting a suitable member for insertion into the box, compressing the member, inserting it into the box, and pouring concrete around the box. The resilient member may subsequently be removed and reused in another box. In another example method, a supply of resilient members of different shapes and sizes is provided for insertion into differently sized boxes.10-02-2008

Donald M. Klein, Mchenry, IL US

Patent application numberDescriptionPublished
20080236857METHOD AND SYSTEM FOR PREVENTING INTRUSION OF POURED CONCRETE IN AN ELECTRICAL OR TELECOMMUNICATIONS BOX - The present invention is directed to a method and system for preventing intrusion of viscous poured concrete into electrical or telecom boxes using resilient members having a top surface that fills the surface opening of the box it is inserted into where the spring back of the resilient member insures a proper seal around the surface opening. An example method for preventing intrusion of poured concrete into a box comprises selecting a suitable member for insertion into the box, compressing the member, inserting it into the box, and pouring concrete around the box. The resilient member may subsequently be removed and reused in another box. In another example method, a supply of resilient members of different shapes and sizes is provided for insertion into differently sized boxes.10-02-2008

Jeffrey D. Klein, Princeville, IL US

Patent application numberDescriptionPublished
20090138185System and method for detecting misassembly of an exhaust aftertreatment system of a machine - A method of detecting an assembly condition, such as, for example, a misassembly, of an exhaust aftertreatment system of a machine includes a step of executing an aftertreatment assembly diagnostic algorithm. The executing step includes detecting an electronic identification feature of an aftertreatment component of the exhaust aftertreatment system, and comparing the electronic identification feature to an expected value.05-28-2009

Kevin J. Klein, Metamora, IL US

Patent application numberDescriptionPublished
20110084044Lightweight High-Performance Pipelayer - A pipelayer providing higher lifting capacities without adding weight or size to an undercarriage or boom of the pipelayer is disclosed. The pipelayer is designed and sized to have a maximum lifting capacity when the boom is extended from the undercarriage a predetermined, relatively short distance. However, in use the boom often needs to extend further away from the undercarriage, and in so doing the lifting capacity of the pipelayer decreases. The present disclosure provides additional lifting capacity in that extended range by selectively deploying a counterweight away from the undercarriage once the boom is extended past the predetermined distance. In so doing, not only is the lifting capacity of the pipelayer increased, but the size and weight of the undercarriage and boom are not increased. This enables standard sized undercarriages and other supporting structure to be used, thereby aiding in maneuverability and shipping of the pipelayers, while at the same time reducing manufacturing and usage costs.04-14-2011

Larry L. Klein, Lake Forest, IL US

Patent application numberDescriptionPublished
20100029686HCV PROTEASE INHIBITORS AND USES THEREOF - This invention relates to: (a) compounds of formula I and salts thereof that, inter alia, are useful as hepatitis C virus (HCV) inhibitors; (b) intermediates useful for the preparation of such compounds and salts; (c) pharmaceutical compositions comprising such compounds and salts; and (d) methods of use of such compounds, salts, and compositions.02-04-2010
20100249181HIV Protease Inhibiting Compounds - A compound of the formula09-30-2010
20100286032PRODRUGS OF HIV PROTEASE INHIBITORS - A compound of the formula11-11-2010
20110003827HIV protease inhibiting compounds - A compound of the formula01-06-2011

Patent applications by Larry L. Klein, Lake Forest, IL US

Laurence C. Klein, Hashmonaim, IL US

Patent application numberDescriptionPublished
20110299124Distributed Computer Architecture and Process for Document Management - A system and/or method enables a typical PC user to add electronic paper processing to their existing business process. The system and/or method extends the notion of copying from a process that involves paper going through a conventional copier device, to a process that involves paper being scanned from a device at one location and copied to a device at another location. In its more sophisticated form, the system and/or method can copy paper from a device at one location directly into a business application residing on a network or on the Internet, or visa versa. The system and/or method is software that manages paper so that it can be electronically and seamlessly copied in and out of devices and business applications (such as Microsoft Office, Microsoft Exchange, Lotus Notes) with an optional single-step operation. The system and/or method can reside on a PC, LAN/WAN server, digital device (such as a digital copier), or on a web server to be accessed over the Internet.12-08-2011

Mark Anthony Klein, Metamora, IL US

Rhett Ronald Klein, Chicago, IL US

Patent application numberDescriptionPublished
20110021525P70S6 Kinase Modulators and Method of Use - The invention provides compounds and methods for inhibition of kinases, more specifically p70S6 kinases. The invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration, chemoinvasion and metabolism. Compounds of the invention inhibit, regulate and/or modulate kinase receptor signal transduction pathways related to the changes in cellular activities as mentioned above, and the invention includes compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions.01-27-2011

Robert J. Klein, Chicago, IL US

Patent application numberDescriptionPublished
20080219543DOCUMENT IMAGING AND PROCESSING SYSTEM - A document processing system comprising one or more document scanning devices that extract information from document images that uniquely identify a document. The system further comprises a central processor remotely connected to the document scanning devices. The central processor is configured to receive the document images and the extracted information from the document scanning devices and is further configured to execute a correction routine configured to adjust errors in the extracted information from the document image.09-11-2008
20090001661SYSTEM AND METHOD FOR PROCESSING BATCHES OF DOCUMENTS - A method of processing documents by receiving at least a batch of documents and a separator card in an input receptacle of a document processing device. The separator card includes a conductive material disposed on one side, and a barcode indicative of the source of the batch of documents. The documents and separator card are transported via a transport mechanism past an evaluation unit and a field-effect sensor, respectively. The document processing device evaluates each document, determines whether the document meets or fails predetermined criteria, and detects the presence of the conductive material when a separator card is transported past the sensor. The source identification information from each separator card is entered into a memory of the document processing device after all the documents from the corresponding batch of documents have met the predetermined criteria. Feeder operation is paused between each batch long enough to verify that the previous batch closed successfully. Pausing feeder operation to address document anomalies before subsequent batches are processed promotes batch integrity and reduces operator confusion.01-01-2009
20090087076SYSTEM AND METHOD FOR PROCESSING CURRENCY BILLS AND TICKETS - A method of processing documents includes receiving a stack of documents including currency bills and substitute currency media. Each substitute currency medium has at least one barcode. The method further includes transporting the stack of documents via a transport mechanism, one document at a time, along a transport path and denominating with a currency detector each of the currency bills in the stack of documents. The currency detector is positioned adjacent to the transport path. The method further includes scanning with a barcode scanner a barcode on each substitute currency medium in the stack of documents. The barcode scanner is positioned adjacent to the transport path. The method further includes imaging with an image scanner each substitute currency medium in the stack of documents to generate a raw image file of the substitute currency medium. The image scanner is positioned adjacent to the transport path.04-02-2009
20100163366Currency Handling System Having Multiple Output Receptacles - A method and apparatus for handling bill jams within a currency processing device is provided. The device includes a transport mechanism adapted to transport bills along a transport path, one at a time, from the input receptacle past an evaluation unit into a plurality of output receptacles. At least one of the output receptacles includes a holding area and a storage area. A plurality of bill passage sensors are sequentially disposed along the transport path that are adapted to detect the passage of a bill as each bill is transported past each sensor. An encoder is adapted to produce an encoder count for each incremental movement of the transport mechanism. A controller counts the total number of bills transported into each of the holding areas and the total number of bills moved from a holding area to a corresponding storage area after a predetermined number of bills have been transported into the holding area. The controller tracks the movement of each of the bills along the transport path into each of the holding areas with the plurality of bill passage sensors. The presence of a bill jam is detected when a bill is not transported past one of the plurality of bill passage sensors within a requisite number of encoder counts. The operation of the transport mechanism is suspended upon detection of a bill jam. The bills from each of the holding areas are moved to the corresponding storage areas upon suspension of the operation of the transport mechanism. Remaining bills are then flushed from the transport path after moving the bills from each of the holding areas to the corresponding storage areas upon suspension of the operation of the transport mechanism.07-01-2010
20110255767CURRENCY PROCESSING SYSTEM WITH FITNESS DETECTION - In one aspect, a method of processing currency in a currency processing machine includes the act of retrieving, from a plurality of input currency bills, characteristic information from each of the bills, the characteristic information itself including at least a first characteristic information relating to fitness. The method also includes the act of assigning to each currency bill one of a plurality of fitness types and fitness levels relating to the first characteristic information of the bill, at least one of the fitness types and the fitness levels being defined by a user. The method also includes the act of outputting each currency bill along one of a plurality of output paths designated by the user to receive currency bills, the output path having a fitness type and/or fitness level assigned to the currency bill.10-20-2011

Patent applications by Robert J. Klein, Chicago, IL US

Ronald T. Klein, Island Lake, IL US

Patent application numberDescriptionPublished
20090050496Product Dispensing System - A product dispensing system and a method of queuing usage of products. A plurality of layers of products, each having multiple items in separate packages, each layer having a carrier with the separate packages being secured to and extending from the carrier. The layers are assembled in a stacked orientation behind a front laver with layers behind the front layer being at least partially concealed and inaccessible. Products arc used one layer at a time, and when the separate packages from the front layer are removed, the packages of the next-succeeding layer are exposed for use.02-26-2009
20100193540PRODUCT DISPENSING SYSTEM - A product dispensing system and a method of queuing usage of products. A plurality of layers of products, each having multiple items in separate packages, each layer having a carrier with the separate packages being secured to and extending from the carrier. The layers are assembled in a stacked orientation behind a front layer with layers behind the front layer being at least partially concealed and inaccessible. Products are used one layer at a time, and when the separate packages from the front layer are removed, the packages of the next-succeeding layer are exposed for use.08-05-2010
20110155612Product Dispensing System - A product dispensing system and a method of queuing usage of products. In one form, a plurality of layers of products, each having multiple items in separate packages, is provided, each layer having a carrier with the separate packages being secured to and extending from the carrier. The layers are assembled in a stacked orientation behind a front layer with layers behind the front layer being at least partially concealed and inaccessible. Products are used one layer at a time, and when the separate packages from the front layer are removed, the packages of the next-succeeding layer are exposed for use. In another form of the invention, the packages for each layer are secured to and extend in series from the carrier for each layer, with a first package secured to the carrier for the layer, and each succeeding package being secured to the next preceding package. The carrier and packages of each layer are secured to one another with successive package connections of increasing strength with increasing distance from a package most distant from the carrier.06-30-2011

Patent applications by Ronald T. Klein, Island Lake, IL US

William Klein, Winetka, IL US

Patent application numberDescriptionPublished
20100272714Anti-ADDL Antibodies and Uses Thereof - The present invention relates to antibodies that differentially recognize multi-dimensional conformations of Aβ-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extracts and are useful in methods of detecting ADDLs and diagnosing Alzheimer's Disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLs, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with soluble oligomers of amyloid β 1-42.10-28-2010

William L. Klein, Winetka, IL US

Patent application numberDescriptionPublished
20090285804Anti-ADDLs antibodies and uses thereof - The invention herein comprises antibodies that bind to amyloid beta-derived diffusible ligands (ADDLs). ADDLs comprise amyloid β protein assembled into soluble, globular, non-fibrillar, oligomeric structures capable of activating specific cellular processes.11-19-2009
20110159013Anti-ADDL Antibodies and Uses Thereof - The present invention relates to antibodies that differentially recognize multi-dimensional conformations of Aβ-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extracts and are useful in methods of detecting ADDLs and diagnosing Alzheimer's Disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with soluble oligomers of amyloid β 1-42.06-30-2011

Patent applications by William L. Klein, Winetka, IL US

William L. Klein, Winnetka, IL US

Patent application numberDescriptionPublished
20080306074Compositions Comprising Addl Receptors, Related Compositions, and Related Methods - Disclosed and claimed herein are compositions comprising ADDL receptors, related compositions, and related methods. ADDL receptors are typically, but perhaps not exclusively, localized at the post-synaptic density (PSD) of neuronal cells. Related compositions include, but are not limited to, compounds that affect, positively or negatively, ADDL binding to neuronal cells, either via one or more receptors localized at the post-synaptic density (PSD) or otherwise. Related methods include, but are not limited to, procedures to screen for compounds that affect, either positively or negatively, ADDL binding to neuronal cells, either via one or more receptors localized at the post-synaptic density (PSD) or otherwise. Other related methods include, but are not limited to, prevention and treatment of ADDL-related diseases, such as Alzheimer's disease, mild cognitive impairment, Down's syndrome, and the like, using compositions that inhibit, block, or otherwise interfere with ADDL binding to one or more receptors localized at the post-synaptic density of neuronal cells.12-11-2008

Patent applications by William L. Klein, Winnetka, IL US

Yosef Klein, Skokie, IL US

Patent application numberDescriptionPublished
20080279344Emergency telephone system and method - An emergency telephone system has a dual mode, hybrid emergency telephone station connected with a central station through both a digital ethernet connection for digital VOIP communication and through a wire line for analog communication. Circuitry at the dual mode emergency station connects a user terminal with the digital ethernet connection and the wire line. A processor forming a part of the circuitry directs communication through the ethernet connection if operative and through the analog wire connection if the ethernet connection is inoperative.11-13-2008