King, CA
Andrew King, Waterdown CA
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20160081960 | INHIBITORS OF METALLO- -LACTAMASE-ENZYMES - The present application relates to combination treatments for bacterial infections. For example, the application relates to the use of one or more β-lactam antibiotics and one or more compounds of Formula I: (I) for treatment of a metallo-B-lactamase-expressing bacterial infection or a disease, disorder or condition arising from a metallo-B-lactamase-expressing bacterial infection. | 03-24-2016 |
Andrew Douglas King, Vancouver CA
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20150046681 | SYSTEMS AND DEVICES FOR QUANTUM PROCESSOR ARCHITECTURES - Quantum processor architectures employ unit cells tiled over an area. A unit cell may include first and second sets of qubits where each qubit in the first set crosses at least one qubit in the second set. Angular deviations between qubits in one set may allow qubits in the same set to cross one another. Each unit cell is positioned proximally adjacent at least one other unit cell. Communicatively coupling between qubits is realized through respective intra-cell and inter-cell coupling devices. | 02-12-2015 |
Brent King, Dewinton CA
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20110088702 | Surgical Drape with Control Mechanism - A disposable sterile surgical drape configured for establishing a sterile field around a surgical instrument such as a limb positioner includes a control mechanism associated with the drape in the sterile field that interfaces with, and controls, the surgical instrument. The control mechanism includes a switch and a communication interface that connects to the instrument and the location of the switch may be moved to a desired position within the sterile field. | 04-21-2011 |
Brian W. King, Calgary CA
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20130347028 | HOSPITALITY MEDIA SYSTEM OPERATED BY MOBILE DEVICE - A hospitality media system includes a media system controller and a plurality of controllable devices operable by the media system controller, each of a plurality of rooms having one or more in-room controllable devices. A communication module performs data communications with a mobile device. An authentication module receives identification information from the mobile device, determines a registered room currently associated with the identification information, and includes in an authorized subset of the controllable devices for which the mobile device is authorized to operate at least the in-room controllable devices of the registered room. The media system controller operates the authorized subset of the controllable devices in dependence upon commands received from the mobile device. | 12-26-2013 |
20140026162 | METHOD OF PROVIDING CUSTOMIZED HOSPITALITY MEDIA FUNCTIONS AT A PLURALITY OF SET-TOP BOXES BEING CONNECTED TO AN RF COAX NETWORK, AND HOSPITALITY MEDIA SYSTEM THEREOF - A hospitality media system includes a plurality of set-top boxes (STBs) coupled to a radio frequency (RF) coax network. Each STB has an identifier for identifying the STB. A content source broadcasts media content to the STBs utilizing the RF coax network and an update server distributes software data to the STBs. The software data causes a particular STB to perform a media function customized for the particular STB according to the identifier of the particular STB. | 01-23-2014 |
20140359646 | INTEGRATING CONTENT ON REMOTE DEVICE ACCESSIBLE VIA INTERNET WITH HOSPITALITY MEDIA SYSTEM - A hospitality media system includes a media system controller and a plurality of media devices located in a plurality of rooms and coupled to the media system controller. Each room has one or more in-room media devices located therein for performing a media function. A connection port allows a user of a room to establish data communications between the media system controller and a guest device. The media system controller is coupled to the connection port and configured to catalogue guest content available on the guest device to thereby form a guest content list, associate the guest content with one or more associated rooms at least including the user's room, and perform the media function utilizing content selected from the guest content list only on the in-room media devices located within the one or more associated rooms. | 12-04-2014 |
20150326890 | PLAYING PAY-PER-VIEW PROGRAM AT SET-TOP BOX CONNECTED TO ONE-WAY BROADCAST-ONLY RF COAX NETWORK AFTER RECEIVING PASSKEY TARGETING IDENTIFIER OF THAT SET-TOP BOX FROM USER - A hospitality media system includes a plurality of set-top boxes (STBs) coupled to a radio frequency (RF) coax network. Each STB has an identifier for identifying the STB. A content source broadcasts media content to the STBs utilizing the RF coax network and an update server distributes software data to the STBs. The software data causes a particular STB to perform a media function customized for the particular STB according to the identifier of the particular STB. | 11-12-2015 |
20150350017 | AUTOMATED ENTRY OF HIDDEN SERVICE-CONFIGURATION MENU FOR TARGET CONFIGURABLE DEVICE SELECTED FROM PLURALITY OF CONFIGURABLE DEVICES IN ROOMS OF HOSPITALITY ESTABLISHMENT - A configuration apparatus includes a user interface allowing a user to initiate configuration of at least a target configurable device selected from a plurality of configurable devices. A command module is coupled to the user interface for dynamically generating a sequence of commands required to configure the target configurable device. The sequence of commands includes commands for entering a hidden service-configuration menu of the target configurable device. A communication module is coupled to the command module for transmitting the sequence of commands to the target configurable device. | 12-03-2015 |
Brynn King, Waterloo CA
Patent application number | Description | Published |
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20150295600 | MOBILE WIRELESS COMMUNICATIONS DEVICE PROVIDING ENHANCED INTERFERENCE MITIGATION FROM WIRELINE TRANSMITTER AND RELATED METHODS - A mobile wireless communications device may include a housing, a wireless receiver carried by the housing and configured to receive communication signals over a wireless frequency range, a wireline transmitter carried by the housing and configured to transmit communication signals at a frequency overlapping the wireless frequency range, and a controller carried by the housing and coupled with the wireless receiver and the wireline transmitter. The controller may be configured to determine when the wireless receiver is to begin receiving and, based thereon, switch the wireline transmitter to a suspended communication mode during which transmission is disabled. The controller may also be configured to determine when the wireless receiver has completed receiving and, based thereon, switch the wireline transmitter to a normal communication mode in which transmission is enabled. | 10-15-2015 |
Cecil E. King, Mississauga CA
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20110264436 | CLOCK SYNCHRONIZATION IN A MODULAR CIRCUIT EMULATION SYSTEM - A modular circuit emulation system includes a global clock generator that generates a plurality of clock signals. A plurality of emulation boards each include at least one programmable circuit and a clock buffer. The clock buffer generates at least one synchronized clock signal for clocking the programmable circuit or circuits, based on at least one of the plurality of global clock signals. | 10-27-2011 |
Chadwick King, North Vancouver CA
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20100233154 | TARGETED BINDING AGENTS DIRECTED TO HEPARANASE AND USES THEREOF 463 - The invention relates to targeted binding agents that specifically bind to heparanase and inhibit the biological activity of heparanase and uses of such agents. More specifically the invention relates to fully human monoclonal antibodies directed to that specifically bind to heparanase and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The disclosed targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of heparanase. | 09-16-2010 |
Chadwick T. King, North Vancouver CA
Patent application number | Description | Published |
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20120231013 | POLYPEPTIDES THAT BIND TISSUE INHIBITOR OF METALLOPROTEINASE TYPE THREE (TIMP-3), COMPOSITIONS AND METHODS - The present invention relates to TIMP-3 binding compositions, methods of producing such compositions, and methods of using such compositions, including in the treatment of various conditions. | 09-13-2012 |
20140004107 | ST2 ANTIGEN BINDING PROTEINS | 01-02-2014 |
20140322218 | Antibody Constructs for CDH19 and CD3 - The present invention provides to a antibody construct comprising a first human binding domain capable of binding to human CDH19 on the surface of a target cell and a second domain capable of binding to human CD3 on the surface of a T cell. Moreover, the invention relates to a nucleic acid sequence encoding the antibody construct, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention relates a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct. | 10-30-2014 |
20150218284 | CD27L ANTIGEN BINDING PROTEINS - The present invention relates to CD27L antigen binding proteins, such an antibodies, polynucleotides encoding said CD27l antigen binding proteins, antibody drug conjugate compositions, and methods for diagnosing and treating diseases associated with CD27L expression. | 08-06-2015 |
20150376286 | HUMAN CGRP RECEPTOR BINDING PROTEINS - Antigen binding proteins that bind to human CGRP receptor (CGRP R) are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of CGRP R to CGRP, and are useful in a number of CGRP R related disorders, including the treatment and/or prevention of migraine headaches. | 12-31-2015 |
20160137739 | ONCOSTATIN M RECEPTOR ANTIGEN BINDING PROTEINS - The invention provides anti-oncostatin M receptor-β (OSMR) antigen binding proteins. e.g., antibodies and functional fragments, derivatives, muteins, and variants thereof. OSMR antigen binding proteins interfere with binding of OSM and/or IL-31 to OSMR. In some embodiments, anti-OSMR antigen binding proteins are useful tools in studying diseases and disorders associated with OSMR and are particularly useful in methods of treating diseases and disorders associated with OSMR and binding of OSM and/or IL-31 to OSMR. | 05-19-2016 |
Chadwick T. King, N. Vancouver CA
Patent application number | Description | Published |
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20100172895 | Human CGRP Receptor Binding Proteins - Antigen binding proteins that bind to human CGRP receptor (CGRP R) are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of CGRP R to CGRP, and are useful in a number of CGRP R related disorders, including the treatment and/or prevention of migraine headaches. | 07-08-2010 |
Chadwick T. King, Vancouver CA
Patent application number | Description | Published |
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20090155282 | ANTIBODIES DIRECTED TO THE DELETION MUTANTS OF EPIDERMAL GROWTH FACTOR RECEPTOR AND USES THEREOF - The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided. | 06-18-2009 |
20090156790 | ANTIBODIES DIRECTED TO THE DELETION MUTANTS OF EPIDERMAL GROWTH FACTOR RECEPTOR AND USES THEREOF - The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided. | 06-18-2009 |
20090175887 | ANTIBODIES DIRECTED TO THE DELETION MUTANTS OF EPIDERMAL GROWTH FACTOR RECEPTOR AND USES THEREOF - The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided. | 07-09-2009 |
20100111979 | ANTIBODIES DIRECTED TO THE DELETION MUTANTS OF EPIDERMAL GROWTH FACTOR RECEPTOR AND USES THEREOF - The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided. | 05-06-2010 |
20130071410 | Human CGRP Receptor Binding Proteins - Antigen binding proteins that bind to human CGRP receptor (CGRP R) are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of CGRP R to CGRP, and are useful in a number of CGRP R related, disorders including the treatment and/or prevention of migraine headaches. | 03-21-2013 |
Chadwick Terence King, North Vancouver CA
Patent application number | Description | Published |
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20090326202 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 12-31-2009 |
20110027287 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 02-03-2011 |
20110135657 | HUMAN ANTIGEN BINDING PROTEINS THAT BIND BETA-KLOTHO, FGF RECEPTORS AND COMPLEXES THEREOF - The present invention provides compositions and methods relating to or derived from antigen binding proteins activate FGF21-mediated signaling. In embodiments, the antigen binding proteins specifically bind to (i) β-Klotho; (ii) FGFR1c, FGFR2c, FGFR3c or FGFR4; or (iii) a complex comprising β-Klotho and one of FGFR1c, FGFR2c, FGFR3c, and FGFR4. In some embodiments the antigen binding proteins induce FGF21-like signaling. In some embodiments, an antigen binding protein is a fully human, humanized, or chimeric antibodies, binding fragments and derivatives of such antibodies, and polypeptides that specifically bind to (i) β-Klotho; (ii) FGFR1c, FGFR2c, FGFR3c or FGFR4; or (iii) a complex comprising β-Klotho and one of FGFR1c, FGFR2c, FGFR3c, and FGFR4. Other embodiments provide nucleic acids encoding such antigen binding proteins, and fragments and derivatives thereof, and polypeptides, cells comprising such polynucleotides, methods of making such antigen binding proteins, and fragments and derivatives thereof, and polypeptides, and methods of using such antigen binding proteins, fragments and derivatives thereof, and polypeptides, including methods of treating or diagnosing subjects suffering from type 2 diabetes, obesity, NASH, metabolic syndrome and related disorders or conditions. | 06-09-2011 |
20120020976 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 01-26-2012 |
20120027765 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 02-02-2012 |
20120213797 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 08-23-2012 |
20120251544 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 10-04-2012 |
20120328616 | HUMAN ANTIGEN BINDING PROTEINS THAT BIND TO A COMPLEX COMPRISING BETA-KLOTHO AND AN FGF RECEPTOR - The present invention provides compositions and methods relating to or derived from antigen binding proteins capable of inducing B-Klotho, and or FGF21-like mediated signaling. | 12-27-2012 |
20130058944 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 03-07-2013 |
20130078237 | CD27L ANTIGEN BINDING PROTEINS - The present invention relates to CD27L antigen binding proteins, such an antibodies, polynucleotides encoding said CD27l antigen binding proteins, antibody drug conjugate compositions, and methods for diagnosing and treating diseases associated with CD27L expression. | 03-28-2013 |
20130079501 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 03-28-2013 |
20130085265 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 04-04-2013 |
20130129725 | HUMAN FGF RECEPTOR AND BETA-KLOTHO BINDING PROTEINS - The present invention provides compositions and methods relating to or derived from antigen binding proteins and antigen binding protein-FGF21 fusions that specifically bind to β-Klotho, or β-Klotho and one or more of FGFR1c, FGFR2c, FGFR3c, and FGFR4. In some embodiments the antigen binding proteins and antigen binding protein-FGF21 fusions induce FGF21-like signaling. In some embodiments, an antigen binding protein or antigen binding protein-FGF21 fusion antigen binding component is a fully human, humanized, or chimeric antibody, binding fragments and derivatives of such antibodies, and polypeptides that specifically bind to β-Klotho, or β-Klotho and one or more of FGFR1c, FGFR2c, FGFR3c, and FGFR4. Other embodiments provide nucleic acids encoding such antigen binding proteins and antigen binding protein-FGF21 fusions, and fragments and derivatives thereof, and polypeptides, cells comprising such polynucleotides, methods of making such antigen binding proteins and antigen binding protein-FGF21 fusions, and fragments and derivatives thereof, and polypeptides, and methods of using such antigen binding proteins and antigen binding protein-FGF21 fusions, fragments and derivatives thereof, and polypeptides, including methods of treating or diagnosing subjects suffering from type 2 diabetes, obesity, NASH, metabolic syndrome and related disorders or conditions. | 05-23-2013 |
20130245235 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 09-19-2013 |
20140235830 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 08-21-2014 |
20140235831 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 08-21-2014 |
20140357850 | NUCLEIC ACID ENCODING ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 12-04-2014 |
20140357851 | NUCLEIC ACID ENCODING ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 12-04-2014 |
20140357852 | NUCLEIC ACID ENCODING ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 12-04-2014 |
20140357853 | NUCLEIC ACID ENCODING ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 12-04-2014 |
20140357854 | NUCLEIC ACID ENCODING ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 12-04-2014 |
20150031870 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 01-29-2015 |
20150087819 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 03-26-2015 |
20150315288 | ANTIBODIES DIRECTED TO THE DELETION MUTANTS OF EPIDERMAL GROWTH FACTOR RECEPTOR AND USES THEREOF - The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided. | 11-05-2015 |
20150322151 | ANTIBODIES TARGETING CDH19 FOR MELANOMA - The present disclosure provides a human antibody or antigen binding fragment thereof or an antibody construct comprising a human binding domain or antigen binding fragment thereof capable of binding to human CDH19 on the surface of a target cell. The disclosure relates to a nucleic acid sequence encoding the antibody or antigen binding fragment thereof contained in the antibody construct, a vector comprising the nucleic acid sequence and a host cell transformed or transfected with the vector. Furthermore, the disclosure relates to a process for the production of the antibody construct of the disclosure, a medical use or a method of treatment using the antibody construct and a kit comprising the antibody or antigen binding fragment thereof or the antibody construct. | 11-12-2015 |
20150368343 | ANTIBODY CONSTRUCTS FOR CDH19 AND CD3 - The present invention provides to a antibody construct comprising a first human binding domain capable of binding to human CDH19 on the surface of a target cell and a second domain capable of binding to human CD3 on the surface of a T cell. Moreover, the invention relates to a nucleic acid sequence encoding the antibody construct, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention relates a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct. | 12-24-2015 |
20160031997 | METHODS AND COMPOSITIONS RELATING TO ANTI-CCR7 ANTIGEN BINDING PROTEINS - The present invention provides compositions and methods relating to antigen binding proteins against CCR7, including antibodies, nucleic acids, vectors, methods of making the antigen binding proteins, and methods of using the antigen binding proteins. | 02-04-2016 |
20160032014 | HUMAN ANTIGEN BINDING PROTEINS THAT BIND TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 - The present invention provides compositions and methods relating to or derived from antigen binding proteins capable of inhibiting PCSK9 binding to LDLR and having increased pH sensitivity, improved binding affinity and/or increased in vivos half life. In embodiments, the antigen binding proteins specifically bind PCSK9 and have increased pH sensitivity, improved binding affinity and/or increased in vivos half life. In some embodiments, an antigen binding protein is a fully human, humanized, or chimeric antibodies, binding fragments and derivatives of such antibodies, and polypeptides that specifically bind PCSK9 Other embodiments provide nucleic acids encoding such antigen binding proteins, and fragments and derivatives thereof, and polypeptides, cells comprising such polynucleotides, methods of making such antigen binding proteins, and fragments and derivatives thereof, and polypeptides, and methods of using such antigen binding proteins, fragments and derivatives thereof, and polypeptides, including methods of treating or diagnosing subjects suffering from hypercholesterolemia and related disorders or conditions. | 02-04-2016 |
20160039945 | HUMAN ANTIGEN BINDING PROTEINS THAT BIND TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 - The present invention provides compositions and methods relating to or derived from antigen binding proteins capable of inhibiting PCSK9 binding to LDLR. In embodiments, the antigen binding proteins specifically bind PCSK9. In some embodiments, an antigen binding protein is a fully human, humanized, or chimeric antibodies, binding fragments and derivatives of such antibodies, and polypeptides that specifically bind PCSK9 Other embodiments provide nucleic acids encoding such antigen binding proteins, and fragments and derivatives thereof, and polypeptides, cells comprising such polynucleotides, methods of making such antigen binding proteins, and fragments and derivatives thereof, and polypeptides, and methods of using such antigen binding proteins, fragments and derivatives thereof, and polypeptides, including methods of treating or diagnosing subjects suffering from hypercholesterolemia and related disorders or conditions. | 02-11-2016 |
David George King, Oakville CA
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20090094695 | ACCOUNT ASSOCIATION GENERATION - Illustrative embodiments provide a computer implemented method, data processing system and computer program product for generating an association between a configuration item and an account. In one illustrative embodiment, the computer implemented method comprises selecting the configuration item requiring account association to create a selected configuration item, and selecting a set of rules for the selected configuration item to form a set of selected rules, wherein the selected set of rules is used to associate configuration items to accounts. Further the method determines whether a match is present between the set of selected rules and the selected configuration item, and responsive to determining that a match is present, obtains account mapping information for an account identified by the match, and associates the selected configuration item with the account using the account mapping information. | 04-09-2009 |
20090132702 | Generic Method for Resource Monitoring Configuration in Provisioning Systems - A generic mechanism and model are provided to capture and store configuration profiles for resource monitors such that monitors can be flexibly deployed, configured, modified, and removed using appropriate sets of parameters and values. As an integral part of resource provisioning, this generic mechanism will require only a generic set of workflows and a generic data model to provision monitors. The provisioning system of the present invention captures and stores response parameters and values from monitors created during initial deployment such that these parameters can be used for later modification and removal of these monitors. | 05-21-2009 |
Denis Junior King, Ottawa CA
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20110191425 | Geospatially Aware Message System and Method - Publishers inject messages containing geospatial data into a content routed network. The subscribers pre-register geospatial data defining an arbitrary geographic region of interest with their subscriptions. The messages are delivered to interested subscribers based on a comparison of the content data and the geospatial data contained in the messages with the corresponding data associated with said pre-registered subscriptions. | 08-04-2011 |
Dustin Robert Russell King, Kelowna CA
Patent application number | Description | Published |
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20140239030 | PACK HARNESS - An apparatus for supporting a back pack from a user comprises a substantially u-shaped harness, the harness having a rear neck portion and a pair of front portions extending therefrom. The apparatus further comprises at least one top harness connector suspended substantially downwardly from the rear neck portion, the at least one top harness connector being selectably attachable to the top of a backpack and a bottom harness connector extending from each front portions, each of the bottom harness connectors being selectably attachable to a bottom of a backpack. A system for supporting a load from a user comprises a harness and a first pack having at least one pack top connector and at least two bottom pack connectors. The harness may be located within an article of clothing. | 08-28-2014 |
Emily Catherine King, Etobicoke CA
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20140306495 | PATIENT CARRIER - A patient carrier comprises a patient support configured to be locatable above a toileting receptacle. The patient support includes a back support portion, a leg support portion, and a seat support portion. The patient support is movable about a first axis between an upright orientation and an inclined orientation. The seat support portion is movable about a second axis relative to the back support portion and leg support portion, and is operable to transition between a seating configuration and a toileting configuration when the patient support is in the inclined orientation. | 10-16-2014 |
20150115119 | CANTILEVERED SUPPORT SYSTEM - A cantilevered support system is provided. The cantilevered support system comprises a vertical support pole and longitudinally extending upper and lower support arm assemblies that are securable to a wall. | 04-30-2015 |
20150117936 | CONNECTOR APPARATUS - A connector apparatus has a first portion and a second portion. The first portion mounts to an upright that has knobby hand grip protrusions. The second portion provides a connection for a laterally extending cross-member. The first portion interacts with the knobby hand grip protrusions to have a combination of a first degree of freedom permitting motion in one direction, while inhibiting motion in a second degree of freedom. The second portion has a releasable connection to the cross-member, and when engaged, has a degree of freedom of motion about an axis of the second portion cross-wise to the axis of the upright. The second portion has a releasable, retained, pin connector with a quarter-turn lock to prevent accidental disengagement. The connection of the second portion is offset such that when two connectors are seated back-to-back their cross-tie connections stand in substantially the same horizontal plane relative to the ground. | 04-30-2015 |
Emily Catherine King, Victoria CA
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20090045383 | Lifting assist device - Disclosed herein is a device for lifting an article comprising a housing having an inner chamber, the housing having a leading edge region in fluid communication with the inner chamber, the leading edge region being arranged to engage an access region between an article and a support surface beneath the article, an elongate tubular member having a first open end region and a second closed end region, the first open end region being directly or indirectly in fluid tight relation with the leading edge region, the elongate tubular member having a first surface in fluid communication with the inner chamber and an opposite second surface, the housing being arranged to provide a retracted position in which the elongate tubular member is held relative to the leading edge region and responsive to an operative pressure within the inner chamber to unfurl beyond the leading edge region to cause the elongate tubular member to migrate along the access region with the second surface in contact with the article and the support surface and with minimal relative motion between the contacting surfaces of the elongate tubular member, the article and the support surface and toward a deployed position in which the tubular member extends a distance exceeding a lateral dimension of the article with opposed ends of the tubular member being available to be employed for lifting the article from the support surface. | 02-19-2009 |
20120181495 | LIFTING ASSIST DEVICE - Disclosed herein is a device for lifting an article comprising a housing having an inner chamber, the housing having a leading edge region in fluid communication with the inner chamber, the leading edge region being arranged to engage an access region between an article and a support surface beneath the article, an elongate tubular member having a first open end region and a second closed end region, the first open end region being directly or indirectly in fluid tight relation with the leading edge region, the elongate tubular member having a first surface in fluid communication with the inner chamber and an opposite second surface, the housing being arranged to provide a retracted position in which the elongate tubular member is held relative to the leading edge region and responsive to an operative pressure within the inner chamber to unfurl beyond the leading edge region to cause the elongate tubular member to migrate along the access region with the second surface in contact with the article and the support surface and with minimal relative motion between the contacting surfaces of the elongate tubular member, the article and the support surface and toward a deployed position in which the tubular member extends a distance exceeding a lateral dimension of the article with opposed ends of the tubular member being available to be employed for lifting the article from the support surface. | 07-19-2012 |
Eric Michael King, Toronto CA
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20160062973 | COLLECTING AND AUDITING STRUCTURED DATA LAYERED ON UNSTRUCTURED OBJECTS - Various embodiments relating to collecting and auditing structured data layered on unstructured object are disclosed. In one embodiment, a field-data tracking form may include a plurality of input fields layered over an unstructured base object (e.g., a legacy form, document, image, diagram, etc.). Each input field may correspond to a different data object having attributes that maintain a full traceable history of changes made to the input field. The field-data tracking form may act as a data-entry vehicle that can be sent to mobile computers to allow field data to be entered directly into input fields corresponding to the data objects, while maintaining the visual layout of the unstructured base object. Furthermore, attributes of discrete data objects from different versions of the field-data tracking form may be searched and displayed via an audit viewing tool graphical user interface (GUI). | 03-03-2016 |
Evan King, Barrie CA
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20140179181 | ADJUSTABLE RESISTANCE KICKBOARD - A variable-resistance kickboard apparatus includes a buoyant kickboard body having an upper surface, a lower surface, and an opening extending through the kickboard body between the upper and lower surfaces. The apparatus also includes a blade extending through the opening and slidably engaged in the opening. The blade can be raised and lowered in the opening to adjust the proportion of the blade that extends below the lower surface. | 06-26-2014 |
Frederick David King, Richmond CA
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20120274760 | METHOD AND PARTICLE ANALYZER FOR DETERMINING A BROAD PARTICLE SIZE DISTRIBUTION - A method and a particle analyzer are provided for determining a particle size distribution of a liquid sample including particles of a lower size range, particles of an intermediate size range, and particles of an upper size range. A dark-field image frame is captured in which the particles of the lower size range and the particles of the intermediate size range are resolved, and a bright-field image frame is captured in which the particles of the intermediate size range and the particles of the upper size range are resolved. Absolute sizes of the particles of the intermediate size range and the particles of the upper size range are determined from the bright-field image frame. Calibrated sizes of the particles of the lower size range are determined from the dark-field image frame by using the particles of the intermediate size range as internal calibration standards. | 11-01-2012 |
20150070699 | METHOD AND PARTICLE ANALYZER FOR DETERMINING A BROAD PARTICLE SIZE DISTRIBUTION - A method and a particle analyzer are provided for determining a particle size distribution of a liquid sample including particles of a lower size range, particles of an intermediate size range, and particles of an upper size range. A dark-field image frame is captured in which the particles of the lower size range and the particles of the intermediate size range are resolved, and a bright-field image frame is captured in which the particles of the intermediate size range and the particles of the upper size range are resolved. Absolute sizes of the particles of the intermediate size range and the particles of the upper size range are determined from the bright-field image frame. Calibrated sizes of the particles of the lower size range are determined from the dark-field image frame by using the particles of the intermediate size range as internal calibration standards. | 03-12-2015 |
Graham J.w. King, London CA
Patent application number | Description | Published |
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20100234960 | Articulating Implant System - An articulating implant system is provided for fixation to a bone. The articulating implant system includes a fixation component for fixation to the bone and an articulating member for articulating against bone or cartilage. Specifically, a modular ulnar implant is provided in accordance with the articulating implant system of the present invention wherein the fixation component is a stem for insertion into the intramedullary canal of the distal ulna and the articulating member is a head for articulating with the radial sigmoid notch. | 09-16-2010 |
James A. King, West Vancouver CA
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20100024603 | REDUCTION OF LIME CONSUMPTION WHEN TREATING REFRACTORY GOLD ORES OR CONCENTRATES - The present invention is directed to a precious metal recovery process in which basic ferric sulphates and/or jarosites are controlled by a number of mechanisms, including control of the oxidation reaction conditions in the first autoclave compartment, hot curing of the autoclave discharge slurry, and/or contacting of the autoclave feed slurry with the hot cured discharge liquid. | 02-04-2010 |
James Brian King, Vancouver CA
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20140100918 | ANALYZING MARKET RESEARCH SURVEY RESULTS USING SOCIAL NETWORKING ACTIVITY INFORMATION - A facility for analyzing market research survey results is described. Among a number of users who have responded to a market research survey, the facility selects users whose responses to the survey match a designated pattern of responses to the survey. The facility then generates output that identifies social networking actions performed by the selected users. | 04-10-2014 |
James M. King, Deep River CA
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20100284505 | Method and Apparatus for Annulus Spacer Detection and Repositioning in Nuclear Reactors - The present invention provides an apparatus for detecting and/or repositioning annulus spacers used to maintain the position of a pressure tube withm a calandria tube of a nuclear reactor. The method comprises the steps of: vibrationally isolating a section of the pressure tube; vibrating the wall of said pressure tube within said isolated section; detecting vibration of the wall at a minimum of two axial positions within said isolated sections; and detecting the reduction in vibration level of the wall at one or more of said axial positions in comparison to the remaining axial positions. The apparatus comprises a tool head to be inserted into the pressure tube, the tool head comprising a first end and a second and a clamping block m each of said ends. The clamping blocks are used to vibrationally isolate a section of the pressure tube located between said ends. The apparatus also comprises piezo-actuators operable to vibrate said pressure tube; and accelerometers used for measuring vibration of said pressure tube. | 11-11-2010 |
20150147426 | DEVICE AND METHOD FOR SURFACE REPLICATION - The present invention provides a replication device for delivering a replicating material to a surface. The device includes an extrusion piston slidably received therein and movable to a dispensing position for expelling the replicating material though an outlet. The device further includes an actuator, wherein the actuator produces stress waves so as to temporarily reduce the viscosity of the material during delivery of said material. Also provided is a method and kit for using the device for obtaining a replica of a surface. | 05-28-2015 |
20160041127 | SUPPORT STRUCTURE LOCATION AND LOAD MEASUREMENT - A tool may be inserted into the pressure tube inside a calandria tube of a fuel channel of a nuclear reactor. Once in position, the tool may act to generate information useful for determining a location for an annulus spacer. Once the annulus spacer has been located, the tool may act to generate information useful for determining a compressive load on the annulus spacer due to the annulus spacer being pinched between the two tubes. In both the locating and the load determining, the tool may act to isolate a section of the pressure tube, excite the isolated section of the pressure tube with vibrations and measure resultant tube vibrations. Tube vibration characteristics, determined from the vibrations, may then be analyzed to determine an axial location along the pressure tube for the annulus spacer and/or determine a load on the annulus spacer. | 02-11-2016 |
20160042819 | METHOD FOR ANNULUS SPACER DETECTION IN NUCLEAR REACTORS - The present invention provides an apparatus for detecting and/or repositioning annulus spacers used to maintain the position of a pressure tube within a calandria tube of a nuclear reactor. The method comprises the steps of: vibrationally isolating a section of the pressure tube; vibrating the wall of said pressure tube within said isolated section; detecting vibration of the wall at a minimum of two axial positions within said isolated sections; and detecting the reduction in vibration level of the wall at one or more of said axial positions in comparison to the remaining axial positions. The apparatus comprises a tool head to be inserted into the pressure tube, the tool head comprising a first end and a second and a clamping block m each of said ends. The clamping blocks are used to vibrationally isolate a section of the pressure tube located between said ends. The apparatus also comprises piezo-actuators operable to vibrate said pressure tube; and accelerometers used for measuring vibration of said pressure tube. | 02-11-2016 |
20160055925 | METHOD FOR ANNULUS SPACER DETECTION AND REPOSITIONING IN NUCLEAR REACTORS - The present invention provides an apparatus for detecting and/or repositioning annulus spacers used to maintain the position of a pressure tube within a calandria tube of a nuclear reactor. The method comprises the steps of: vibrationally isolating a section of the pressure tube; vibrating the wall of said pressure tube within said isolated section; detecting vibration of the wall at a minimum of two axial positions within said isolated sections; and detecting the reduction in vibration level of the wall at one or more of said axial positions in comparison to the remaining axial positions. The apparatus comprises a tool head to be inserted into the pressure tube, the tool head comprising a first end and a second and a clamping block m each of said ends. The clamping blocks are used to vibrationally isolate a section of the pressure tube located between said ends. The apparatus also comprises piezo-actuators operable to vibrate said pressure tube; and accelerometers used for measuring vibration of said pressure tube. | 02-25-2016 |
James Mitchell King, Deep River CA
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20150155059 | PRESSURE-TUBE NUCLEAR REACTOR WITH A LOW PRESSURE MODERATOR AND FUEL CHANNEL ASSEMBLY - A fuel channel assembly for a nuclear reactor may include an inner conduit received within an outer conduit that has an outer upper end connectable to a coolant outlet and an outer lower end. The inner conduit may have an inner upper end connectable to a coolant source and an inner lower end axially spaced apart from the inner upper end and disposed within the outer conduit to enable coolant to circulate from the coolant source to the coolant outlet through both the inner and outer conduits. A fuel bundle chamber may be between an inner surface of the outer conduit and an outer surface of the inner conduit and may at least partially laterally surround the inner conduit. The fuel bundle chamber fluidly connecting the inner lower end and the outer upper end to enable the coolant to flow upward through the fuel bundle chamber. | 06-04-2015 |
20150155060 | PRESSURE-TUBE NUCLEAR REACTOR WITH A LOW PRESSURE MODERATOR AND FUEL CHANNEL ASSEMBLY - A nuclear fuel bundle may include a first end face and a second end face axially spaced apart from the first end face and a plurality of elongate nuclear fuel elements supported by at least one spacer. The plurality of fuel elements and spacer being sized to be removably received within the fuel channel assembly. A coolant tube passage may extend axially through the fuel bundle between a first aperture in the first end face and a second aperture in the second end face. The coolant tube passage sized to removably receive a coolant fluid downflow tube provided in the fuel channel assembly. The tube passage extending from the first end face to the second end face to enable the coolant fluid downflow tube to pass through the fuel bundle. | 06-04-2015 |
Jamie King, St. John'S CA
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20160132886 | FRAUD DETECTION SYSTEMS AND METHODS - Systems and methods disclosed herein related to a fraud detection system that receives data from multiple sources and normalizes the data to create transaction data using overlapping data from the multiple sources. Fraud analysis is performed using a probabilistic approach to alert generation, wherein alerts are only sent to customers when the probability of fraud exceeds a threshold. As a result, false positives are avoided. | 05-12-2016 |
Jayson King, Corning CA
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20110067761 | Storage Tank Containment Apparatus - A secondary containment apparatus for storage tanks has a floor, and side walls sealed to the floor to form a containment structure configured to be placed on a transport vehicle for transport along a public road as a single unit so further assembly at the work site is not required. The floor and the side walls are configured to support the side walls in an upright orientation, and lifting lugs are configured for connection to a crane for lifting the apparatus. A wall port can be provided in a lower portion of the side wall to facilitate connection of the storage tank inside the structure to a conduit outside the structure. | 03-24-2011 |
Jayson S. King, Corning CA
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20130160860 | LOAD BOX FOR STORAGE TANK CONTAINMENT - A load box for containing liquid spillage has a container; with an upper access opening with a cover, attachable to a wall of a containment structure containing a liquid storage tank. An input opening configured to receive a discharge end of a tank conduit, and an output opening is configured to receive a suction end of a transport conduit. The container encloses a releasable connection between the suction end of the transport conduit and the discharge end of the tank conduit. An overflow opening is located such that liquid rising in the container flows through the overflow opening before rising to a level where liquid flows through one of the input and output openings, and an overflow conduit attached to the overflow opening is configured such that when a liquid level in the container rises to the overflow opening, liquid flows through the overflow conduit into the structure interior. | 06-27-2013 |
Lawrence King, Newmarket CA
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20130113786 | SYSTEMS AND METHODS FOR MASK ADJUSTMENT IN 3D DISPLAY TECHNOLOGY - Certain embodiments relate to systems and methods for presenting a stereoscopic, 3-dimensional image to a user. The system may comprise a mobile device having a camera and a pixel-selective mask overlaying a display. The system may perform facial and object recognition techniques to determine the location of the user's eyes. Subsequently, the system may adjust the mask so as to maintain an optimal stereoscopic effect for the user, regardless of the user's position. | 05-09-2013 |
Lawrence J. King, Newmarket CA
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20090157914 | DISPLAY SYSTEM WITH FRAME REUSE USING DIVIDED MULTI-CONNECTOR ELEMENT DIFFERENTIAL BUS CONNECTOR - A method includes reducing power of a first graphics processor by disabling or not using its rendering engine and leaving a display engine of the same first graphics processor capable of outputting display frames from a corresponding first frame buffer to a display. A display frame is rendered by a second graphics processor while the rendering engine of the first graphics processor is in a reduced power state, such as a non-rendering state. The rendered frame is stored in a corresponding second frame buffer of the second graphics processor, such as a local frame buffer and copied from the second frame buffer to the first frame buffer. The copied frame in the first frame buffer is then displayed on a display while the rendering engine of the first graphics processor is in the reduced power state. Accordingly thermal output and power output is reduced with respect to the first graphics processor since it does not do frame generation using its rendering engine, it only uses its display engine to display frames generated by the second graphics processor. | 06-18-2009 |
20090157938 | ELECTRONIC DEVICES USING DIVIDED MULTI-CONNECTOR ELEMENT DIFFERENTIAL BUS CONNECTOR - In one example an electronic device includes a housing that includes an A/C input or DC input, and at least one circuit substrate that includes electronic circuitry, such as graphics processing circuitry that receives power based on the A/C input or DC input. The electronic device also includes a divided multi-connector element differential bus connector that is coupled to the electronic circuitry. The divided multi-connector element differential bus connector includes a single housing that connects with the circuit substrate and the connector housing includes therein a divided electronic contact configuration comprised of a first group of electrical contacts divided from an adjacent second group of mirrored electrical contacts wherein each group of electrical connects includes a row of at least lower and upper contacts. In one example, the electronic device housing includes air flow passages, such as grills, adapted to provide air flow through the housing. The electronic device housing further includes a passive or active cooling mechanism such as a fan positioned to cool the circuitry during normal operation. In one example, the electronic device does not include a host processor and instead a host processor is in a separate electronic device that communicates with the graphics processing circuitry through the divided multi connector element differential bus connector. In another example, a CPU (or one or more CPUs) is also co-located on the circuit substrate with the circuitry to provide a type of parallel host processing capability with an external device. | 06-18-2009 |
20110063308 | DISPLAY SYSTEM WITH FRAME REUSE USING DIVIDED MULTI-CONNECTOR ELEMENT DIFFERENTIAL BUS CONNECTOR - A method includes reducing power of a first graphics processor by disabling or not using its rendering engine and leaving a display engine of the same first graphics processor capable of outputting display frames from a corresponding first frame buffer to a display. A display frame is rendered by a second graphics processor while the rendering engine of the first graphics processor is in a reduced power state, such as a non-rendering state. The rendered frame is stored in a corresponding second frame buffer of the second graphics processor, such as a local frame buffer and copied from the second frame buffer to the first frame buffer. The copied frame in the first frame buffer is then displayed on a display while the rendering engine of the first graphics processor is in the reduced power state. Accordingly thermal output and power output is reduced with respect to the first graphics processor since it does not do frame generation using its rendering engine, it only uses its display engine to display frames generated by the second graphics processor. | 03-17-2011 |
20120221758 | ELECTRONIC DEVICES USING DIVIDED MULTI CONNECTOR ELEMENT DIFFERENTIAL BUS CONNECTOR - In one example an electronic device includes a housing that includes an A/C input or DC input, and at least one circuit substrate that includes electronic circuitry, such as graphics processing circuitry that receives power based on the A/C input or DC input. The electronic device also includes a divided multi- connector element differential bus connector that is coupled to the electronic circuitry. The divided multi-connector element differential bus connector includes a single housing that connects with the circuit substrate and the connector housing includes therein a divided electronic contact configuration comprised of a first group of electrical contacts divided from an adjacent second group of mirrored electrical contacts wherein each group of electrical connects includes a row of at least lower and upper contacts. | 08-30-2012 |
Martin A. King, Montreal CA
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20110120005 | HYDROPONIC PLANT GROWTH SYSTEMS WITH ACTIVATED CARBON AND/OR CARBONIZED FIBER SUBSTRATES - A method and apparatus for growing plants (P) hydroponically includes a plant substrate material ( | 05-26-2011 |
Ray King, Ontorio CA
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20140117002 | RADIANT HEATING SYSTEM - A radiant heating system includes a housing and a plurality of heating elements. The housing includes a top cover configured to cover and seal an upper surface of the housing and a coolant directing enclosure positioned on an upper interior surface of the top cover. The top cover includes a plurality of openings, an inlet configured to allow a coolant to enter into the housing and an outlet configured to allow the coolant to exit the housing. The plurality of heating elements are configured to be inserted into the plurality of openings of the top cover such that the plurality of heating elements project into the housing and contact a coolant. A diameter of the inlet is greater than a diameter of the outlet. | 05-01-2014 |
Ray King, Pickering CA
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20090283923 | HUMIDIFIER SYSTEM - A humidifier system comprising a housing having a reservoir extending therethrough for passage of liquid through the humidifier system. Liquid from a liquid receptacle is transferred to the reservoir in the housing. The flow rate of the liquid can be controlled so as to adjust the water rate within the reservoir. The housing provides at least one opening defined therein separately positioned within the housing from the reservoir but accessible thereto, and an electric heating element is inserted therein, the heating element projecting into the reservoir whereby the heating element is in direct contact with the liquid to heat it. The heating element is supplied with electrical power from a power source for enabling the heating element to heat the liquid and create steam within the housing. A safety switch is also provided, in association with the interior of the housing, wherein the safety switch is adapted to turn the heating element off when a temperature of the element exceeds a pre-determined level. Means are also provided for controlling an exhaust flow rate and temperature of the steam exiting the housing. | 11-19-2009 |
20100059599 | CLOSED LOOP HEATING SYSTEM - A heating system comprising a first flow pipe and a second flow pipe which are interconnected at ends thereof to form a closed loop fluid flow circuit. A housing having a passage extending therethrough for passage of water through the housing is interconnected with the fluid flow circuit, and a pump is utilized to circulate water through the fluid flow circuit. The housing provides at least one opening defined therein separate from the passage, and at least one heating element is inserted therein, projecting into the housing, so as to be in direct contact with the water therein. The heating element is powered by a power source for enabling the heating element to heat the water and operate the pump. Radiator panels are connected to the fluid flow circuit, to radiate the heat from the heated water flowing in the fluid flow circuit to a space heated by the heating system. A thermostatic safety control is provided in association with the heating element, which is adapted to turn the heating element off when a temperature of the water exceeds a pre-determined level. In another embodiment, a remote device can be used to selectively activate, or deactivate, the power source in heating the heating element. | 03-11-2010 |
20120223065 | Electro-thermal heating system - An electro-thermal heating system comprising a substantially hollow housing having detachable upper and lower plates for covering and sealing top and bottom surfaces of the housing. The housing has an inlet and an outlet for a flow of coolant to enter into and leave the housing, and has openings defined therein, for insertion of electric heating elements therein to project into the housing and be in direct contact with the coolant to heat it. The inlet and the outlet can be interconnected with piping to form a closed fluid flow circuit. The housing is substantially circular, to circulate flow of the coolant in a circular manner within the housing, and a diameter of the inlet is greater than a diameter of the outlet, to keep coolant in the housing longer to heat it. A pump and a power source can be interconnected to the system to circulate the coolant in the closed fluid flow circuit. | 09-06-2012 |
20120224836 | Electro-thermal heating system - An electro-thermal heating system comprising a substantially hollow housing having detachable upper and lower plates for covering and sealing top and bottom surfaces of the housing. The housing has an inlet and an outlet for a flow of coolant to enter into and leave the housing, and has openings defined therein, for insertion of electric heating elements therein to project into the housing and be in direct contact with the coolant to heat it. The inlet and the outlet can be interconnected with piping to form a closed fluid flow circuit. The housing is substantially circular, to circulate flow of the coolant in a circular manner within the housing, and a diameter of the inlet is greater than a diameter of the outlet, to keep coolant in the housing longer to heat it. A pump and a power source can be interconnected to the system to circulate the coolant in the closed fluid flow circuit. | 09-06-2012 |
20130016959 | Radiant heating system and boiler housing for use thereinAANM King; RayAACI PickeringAACO CAAAGP King; Ray Pickering CA - A radiant heating system comprising a substantially hollow housing having detachable baffle plates internally positioned within the housing. The housing has an inlet and outlet for a flow of coolant to enter into and leave the housing, and a top plate sealing the upper surface of the housing has openings defined therein for insertion of heating elements to project into the housing and be in direct contact with the coolant to heat it. The inlet and the outlet are interconnected with piping to form a closed fluid flow circuit. Two or more baffle plates are used to increase turbulence of the coolant within the housing as it flows through, and temporarily keep coolant in the housing longer to heat it. | 01-17-2013 |
20160032882 | Auxiliary Heating System - An auxiliary heating system comprising interconnected piping which forms a closed fluid flow circuit for permitting a passage of coolant therein, and having formed chamber openings along a length thereof to receive at least one heating element which projects into the closed fluid flow circuit to be in direct contact with, and heat, the coolant. A pump is provided for circulating the coolant, along with a flow switch for monitoring flow of the coolant through the closed fluid flow circuit, wherein if the flow has ceased through the closed fluid flow circuit, the flow switch instructs the system to deactivate the heating elements. | 02-04-2016 |
Ray King, Ajax CA
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20130206744 | Engine pre-heater system - An engine pre-heater system comprising a housing having a passage extending therethrough for passage of coolant through the pre-heater. The housing provides at least one opening defined therein separate from the passage, and an electric heating element is inserted therein, the heating element projecting into the passage whereby the heating element is in direct contact with the coolant to heat it. The heating element is supplied with electrical power from a power source for enabling it to heat the coolant, and a lower end of the heating element is L-shaped, the lower end thus being substantially perpendicular in relationship to the remainder of the heating element, giving the heating element a greater surface area with which to contact, and thus heat the coolant. The engine pre-heater system is also operably able to heat the coolant, engine oil and transmission oil, therefore heating the coolant and warming the engine in a faster and more efficient manner for quick start-ups. | 08-15-2013 |
Scott King, Calgary CA
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20140155735 | Methods, Devices, And Systems Useful In Registration - Methods, devices, and systems for use in accomplishing registration of a patient to a robot to facilitate image guided surgical procedures, such as stereotactic procedures. | 06-05-2014 |
Scott King, Winnipeg CA
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20100026299 | METHOD FOR RADIO-FREQUENCY NUCLEAR MAGNETIC RESONANCE IMAGING - Accumulated spin magnetization phase within a RF MRI procedure can be used for providing an orderly k-space traversal. By operating a transmit array adapted to produce two B1 fields in alternation, where the B1 fields are substantially uniform in amplitude over a sample volume of the MRI setup, and the B1 fields have respective spatial phase distributions such that selection of a difference in spatial derivatives of the spatial phase distributions permits control over a size of a step in k-space applied by successive refocusing pulses for generating the B1 fields in alternation. Each alternating refocusing pulse issued within a T2 time causes a step through k-space in an encoding direction determined by the difference in spatial derivatives. | 02-04-2010 |
20100171499 | RF BASED SPATIALLY SELECTIVE EXCITATION IN MRI - Herein a method for slice selection is provided in an MRI process, the method involves controlling a transmit array by adding low flip angle RF pulses interspersed between refocusing pulses that are used to move a k-space weighting function with respect to one or more B 1 fields used to deposit energy according to a desired k-space weighting function. The low flip angle pulses deposit energy so that an envelope traced by the low flip angle pulses in the k-space weighting function is related to a desired spatially excited region of the sample volume, for example by a Fourier transform, if the phase encoding directions are linear axes that coordinatize the sample volume, and the B 1 fields have linear phase gradients. | 07-08-2010 |
20100296723 | Methods, Devices, and Systems Useful in Registration - Methods, devices, and systems for use in accomplishing registration of a patient to a robot to facilitate image guided surgical procedures, such as stereotactic procedures. | 11-25-2010 |
20150077107 | Method for B0 Field Correction in Magnetic Resonance - In a magnetic resonance (MR) experiment, a method for effectively improving B0 uniformity of a static magnet of a magnetic resonance (MR) apparatus, without shimming magnets or coils involves combining a plurality of RF receive fields, each having a different respective sensitivity map. This method can apply retrospectively to previously acquired data, as long as there is data from different receive fields. | 03-19-2015 |
Stephen King, St. John'S CA
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20150216195 | SEA CUCUMBER PROCESSING APPARATUS AND METHOD - An improved apparatus for processing sea cucumbers having stages for orienting/aligning, cutting, splitting, flattening, eviscerating and cleaning the sea cucumber, and for collecting the eviscerated innards. A method for the automated splitting and evisceration of sea cucumbers using the apparatus of the present disclosure. A flattening plate and trough during the orienting/aligning step relax the sea cucumber and discourage its defence mechanisms. A wedge shaped flattening plate splits and flattens the sea cucumber immediately after the incision. Pronged discs maintain positioning of the sea cucumber during an aggressive wash and brush cleaning cycle, which may be repeated. Optionally, a vacuum may suction off a portion of the innards prior to cleaning. | 08-06-2015 |
Steven Paul King, Stratford CA
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20150351347 | MAIZE HYBRID X70F220 - A novel maize variety designated X70F220 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X70F220 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X70F220 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X70F220, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X70F220. This invention further relates to methods for producing maize varieties derived from maize variety X70F220. | 12-10-2015 |
20150351348 | MAIZE HYBRID X70F222 - A novel maize variety designated X70F222 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X70F222 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X70F222 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X70F222, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X70F222. This invention further relates to methods for producing maize varieties derived from maize variety X70F222. | 12-10-2015 |
20150351349 | MAIZE HYBRID X70F225 - A novel maize variety designated X70F225 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X70F225 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X70F225 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X70F225, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X70F225. This invention further relates to methods for producing maize varieties derived from maize variety X70F225. | 12-10-2015 |
Thomas Ross King, Vancouver CA
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20110315260 | PROTECTIVE PIPE COVER AND SUPPORT APPARATUS - A protective pipe cover and support apparatus is disclosed that provides for secure attachment to an underlying surface, such as a concrete, tarmac or stone surface, for example, and which provides for secure retention and support of multiple pipes or other conduits within the pipe cover and protection of the pipes against loads, impacts and/or other forces applied to the pipe cover. The protective pipe cover includes a load bearing cover element with lateral load bearing supports which bear against an underlying surface, a curved outer web extending between the lateral supports, and a central load bearing support extending between the outer web and an underlying surface, and including an anchor for attachment to the surface. The pipe cover also includes a pipe support with multiple pipe retainer clips for resiliently retaining multiple pipes situated between the outer web of the load bearing cover element, and the underlying surface. | 12-29-2011 |
20120211281 | LOW HEADROOM CONFINED SPACE GEOEXCHANGE DRILLING SYSTEM AND METHOD - A low headroom confined space drilling system is disclosed, comprising a low headroom drilling apparatus, a drilling fluid supply system, a drilling fluid collection system, and a drilling fluid recycling apparatus for supplying a recycled drilling fluid to the drilling apparatus. A method of installing a geoexchange borehole in an interior space of a building is also disclosed, comprising installing a borehole access chamber in a floor slab of a building, positioning a low headroom floor mounted rotary drilling apparatus over the borehole access chamber, providing a pressurized drilling fluid to the drill rod string and powering a rotary downhole drilling device attached to the drill rod string to advance the borehole to a desired depth, recovering a drilling fluid and drill cuttings from the borehole, removing drill cuttings from the recovered drilling fluid using the drilling fluid recycling apparatus and returning a recycled drilling fluid to the drilling apparatus. | 08-23-2012 |
20150211301 | LOW HEADROOM CONFINED SPACE GEOEXCHANGE DRILLING SYSTEM AND METHOD - A low headroom confined space drilling system is disclosed, comprising a low headroom drilling apparatus, a drilling fluid supply system, a drilling fluid collection system, and a drilling fluid recycling apparatus for supplying a recycled drilling fluid to the drilling apparatus. A method of installing a geoexchange borehole in an interior space of a building is also disclosed, comprising installing a borehole access chamber in a floor slab of a building, positioning a low headroom floor mounted rotary drilling apparatus over the borehole access chamber, providing a pressurized drilling fluid to the drill rod string and powering a rotary downhole drilling device attached to the drill rod string to advance the borehole to a desired depth, recovering a drilling fluid and drill cuttings from the borehole, removing drill cuttings from the recovered drilling fluid using the drilling fluid recycling apparatus and returning a recycled drilling fluid to the drilling apparatus. | 07-30-2015 |
William Allan King, Guelph CA
Patent application number | Description | Published |
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20100136512 | EMBRYO CULTURE MEDIA CONTAINING THYROID HORMONE - The disclosure relates to the use of culture media containing thyroid hormones or analogs thereof, and includes methods and uses thereof for embryo culture, embryo production, embryo maturation, improved survival of embryos and improved viability of embryos post cryopreservation. | 06-03-2010 |