| Patent application number | Description | Published |
|---|
| 20080249070 | Cycloalkane-Containing Sphingosine 1-Phospate Agonists - The present invention provides sphingosine-1-phosphate analogs that are potent, and selective agonists at one or more S1P receptors, specifically the S1P | 10-09-2008 |
| 20080318901 | Novel Lysophosphatidic Acid Receptor Selective Antagonists - The present invention is directed to compositions comprising lysophosphatidic acid analogs and methods of using such analogs as agonist or antagonists of LPA receptor activity. In addition the invention is directed to LPA receptor agonists that vary in the degree of selectivity at individual LPA receptors (i.e. LPA1, LPA2 and LPA3). More particularly the present invention is directed to LPA analogs wherein the glycerol is replaced with ethanolamine and a variety of substitutions have been linked at the second carbon atom. | 12-25-2008 |
| 20090042955 | BICYCLIC SPHINGOSINE 1-PHOSPHATE ANALOGS - Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors. | 02-12-2009 |
| 20090062238 | METHOD FOR TREATMENT OF NEUROPATHIC PAIN - Compounds and methods useful for preventing and treating pain, e.g., neuropathic pain, in a subject in need thereof are provided. The compounds can be “S1P modulating” agents that are capable of inducing a detectable change in S1P receptor activity. | 03-05-2009 |
| 20090105315 | PHENYL-CYCLOALKYL AND PHENYL-HETEROCYCLIC DERIVATIVES AS S1P RECEPTOR AGONISTS - Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors. | 04-23-2009 |
| 20090137531 | Aryl Amide Sphingosine 1- - The present invention provides compounds that have antagonist activity at the S1P | 05-28-2009 |
| 20090197835 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS - The present invention provides LPA analogs that are antagonists at the LPA receptors. | 08-06-2009 |
| 20090253759 | TETRALIN ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE AGONIST ACTIVITY - Tetralin analogs that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at S1P receptors. | 10-08-2009 |
| 20090253760 | HYDRINDANE ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST ACTIVITY - Hydrindane analogs that have agonist activity at one or more of the S | 10-08-2009 |
| 20090253761 | BENZOCYCLOHEPTYL ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR ACTIVITY - Benzocycloheptyl analogs that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at S1P receptors. | 10-08-2009 |
| 20100016258 | PHOSPHONATE DERIVATIVES AS AUTOTAXIN INHIBITORS - The present invention provides β-hydroxy phosphonate compounds that are autotaxin inhibitors. | 01-21-2010 |
| 20100240617 | BICYCLIC SPHINGOSINE 1-PHOSPHATE ANALOGS - Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors. | 09-23-2010 |
| 20100249074 | BENZYL-CYCLOALKYL SPHINGOSINE 1-PHOSPHATE RECEPTOR MODULATORS - Sphingosine- | 09-30-2010 |
| 20110106241 | COMPOSITIONS AND METHODS FOR INHIBITING SPHINGOSINE KINASE - Amidine analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumor cells. | 05-05-2011 |
