Patent application number | Description | Published |
20080261327 | Cell Free Assay for Determining a Substance of Interest and Molecular Complexes Used Therefore - The invention involves receptor complexes which include, inter alia, a receptor protein, and a reporter molecule. There is at least one unnatural, or non-naturally occurring amino acid in the receptor molecule. When a ligand interacts with the receptor, the interaction causes the reporter to generate a detectable signal. The complexes are useful in cell free, assay systems and may be used as part of micelles. | 10-23-2008 |
20080274913 | Multiplex Array Useful for Assaying Protein-Protein Interaction - The described invention shows how multiple interactions between two proteins of interest can be determined by observing activation or lack thereof of intracellular proteins, following interaction of ligand and receptor. | 11-06-2008 |
20080288270 | System and method for generating an internet-based mall portal - A method for providing a web-based mall portal for an affiliate that provides access to at least one of merchant web sites and service provider web sites through at least one of merchant information pages and service provider information pages, where the merchant information pages and the service provider pages are at least partially co-branded with the affiliate. In an exemplary embodiment, the method includes the steps of: receiving a request from the affiliate for a mall web site that provides access to the merchant web sites and the service provider web sites through the merchant information pages and the service provider information pages; generating the mall web site; providing the affiliate with administrative access to the mall web site; and providing credit to the affiliate for revenue generating activities conducted at the merchant web sites and service provider web sites as a result of access of the merchant web sites and service provider web sites though the merchant information pages and service provider information pages provided at the mall web site. | 11-20-2008 |
Patent application number | Description | Published |
20110213805 | SEARCH SYSTEMS AND METHODS WITH INTEGRATION OF USER ANNOTATIONS - Computer systems and methods allow users to annotate content items found in a corpus such as the World Wide Web. Annotations, which can include any descriptive and/or evaluative metadata related to a document, are collected from a user and stored in association with that user. Users are able to annotate and view their annotations for any document they encounter while interacting with the corpus, including hits returned in a search of the corpus. Users are also able to search their annotations or to limit searches to documents they have annotated. Metadata from annotations can also be aggregated across users and aggregated metadata applied in generating search results. | 09-01-2011 |
20120173505 | INVERSE SEARCH SYSTEMS AND METHODS - Inverse search systems and methods operate on identifiers of content items in a corpus such as the World Wide Web In an inverse search, the user submits a query that includes an identifier of a target content item in the corpus and receives information (metadata) about the target content item being returned to the user. Many types of metadata can be returned, including ratings or other metadata related to the target content item obtained from users, popularity data specific to the target content item, information about previously submitted forward search queries that led to the target content item being identified as a hit, and metadata extracted from the target content item. | 07-05-2012 |
20120233154 | SEARCH SYSTEMS AND METHODS WITH INTEGRATION OF AGGREGATE USER ANNOTATIONS - Computer systems and methods allow users to annotate content items found in a corpus such as the World Wide Web Annotations, which can include any descriptive and/or evaluative metadata related to a document, are collected from a user and stored in association with that user. Users are able to annotate and view their annotations for any document they encounter while interacting with the corpus, including hits returned in a search of the corpus. Users are also able to search their annotations or to limit searches to documents they have annotated. Metadata from annotations can also be aggregated across users and aggregated metadata applied in generating search results. | 09-13-2012 |
20130179465 | INVERSE SEARCH SYSTEMS AND METHODS - Inverse search systems and methods operate on identifiers of content items in a corpus such as the World Wide Web In an inverse search, the user submits a query that includes an identifier of a target content item in the corpus and receives information (metadata) about the target content item being returned to the user. Many types of metadata can be returned, including ratings or other metadata related to the target content item obtained from users, popularity data specific to the target content item, information about previously submitted forward search queries that led to the target content item being identified as a hit, and metadata extracted from the target content item. | 07-11-2013 |
20140108387 | INVERSE SEARCH SYSTEMS AND METHODS - Inverse search systems and methods operate on identifiers of content items in a corpus such as the World Wide Web In an inverse search, the user submits a query that includes an identifier of a target content item in the corpus and receives information (metadata) about the target content item being returned to the user. Many types of metadata can be returned, including ratings or other metadata related to the target content item obtained from users, popularity data specific to the target content item, information about previously submitted forward search queries that led to the target content item being identified as a hit, and metadata extracted from the target content item. | 04-17-2014 |
20140114947 | Search Systems and Methods with Integration of User Annotations - Computer systems and methods allow users to annotate content items found in a corpus such as the World Wide Web. Annotations, which can include any descriptive and/or evaluative metadata related to a document, are collected from a user and stored in association with that user. Users are able to annotate and view their annotations for any document they encounter while interacting with the corpus, including hits returned in a search of the corpus. Users are also able to search their annotations or to limit searches to documents they have annotated. Metadata from annotations can also be aggregated across users and aggregated metadata applied in generating search results. | 04-24-2014 |
20140289232 | Search system and methods with integration of user annotations from a trust network - Computer systems and methods incorporate user annotations (metadata) regarding various pages or sites, including annotations by a querying user and by members of a trust network defined for the querying user into search and browsing of a corpus such as the World Wide Web. A trust network is defined for each user, and annotations by any member of a first user's trust network are made visible to the first user during search and/or browsing of the corpus. Users can also limit searches to content annotated by members of their trust networks or by members of a community selected by the user. | 09-25-2014 |
Patent application number | Description | Published |
20120202875 | Method Of Treatment - The present invention relates to methods for treatment or prevention of autoimmune and inflammatory diseases and conditions by inhibiting or modifying histone demethylation. In a further aspect the invention relates to a method for identifying agents useful in said methods of treatment. The invention particularly describes the role of certain histone demethylase enzymes in these diseases and conditions and their use as therapeutic and screening targets. | 08-09-2012 |
20130210892 | Method of Treatment - A method of treating autoimmune and inflammatory diseases or conditions in a mammal, such as a human, which comprises the administration of a inhibitor of the bromodomain-containing protein: SP110 | 08-15-2013 |
20130224204 | Method of Treatment Based on ATAD2 Inhibitors - A method of treating autoimmune and inflammatory diseases or conditions in a mammal, such as a human, which comprises the administration of a inhibitor of the bromodomain-containing protein: ATAD2. | 08-29-2013 |
20130225661 | Inhibitors Of SP140 And Their Use In Therapy - A method of treating autoimmune and inflammatory diseases or conditions in a mammal, such as a human, which comprises the administration of a inhibitor of bromodomain-containing protein: SP140. | 08-29-2013 |
20140024558 | Method of Treatment - The present invention relates to methods for treatment or prevention of autoimmune and inflammatory diseases and conditions by inhibiting or modifying histone demethylation. In a further aspect the invention relates to a method for identifying agents useful in said methods of treatment. The invention particularly describes the role of certain histone demethylase enzymes in these diseases and conditions and their use as therapeutic and screening targets. | 01-23-2014 |
Patent application number | Description | Published |
20120256580 | SYSTEM AND METHOD FOR FAST START-UP OF AN INDUCTION MOTOR - A system for controlling operation of a motor drive during fast start-up of an induction motor is disclosed. The system includes an AC motor drive having a PWM inverter and a control system to generate a command signal to cause the PWM inverter to control an output of the AC motor drive. The control system includes a start-up modulator that is selectively operable during start-up acceleration of the AC motor, the start-up modulator programmed to determine a motor current applied to the AC motor and a voltage of a DC bus, generate a first frequency offset that causes a frequency reference of the command signal to be decreased when the motor current is greater than a reference current threshold, and generate a second frequency offset that causes the frequency reference of the command signal to be increased when the DC bus voltage is greater than a reference voltage threshold. | 10-11-2012 |
20130080793 | DATA PROCESSING SYSTEM POWER DISTRIBUTION USING RESERVE BUS - Some embodiments of the inventive subject matter provide a power distribution system for a data processing system. The power distribution system includes a plurality of uninterruptible power supply (UPS) units, respective ones of which are configured to be coupled to respective loads via respective load busses, at least one reserve bus, a switching circuit configured to selectively couple and decouple the UPS units and the load busses to and from the at least one reserve bus and a control circuit configured to control the switching circuit responsive to a state of the data processing system. The control circuit may be configured to cause the switching circuit to couple the first UPS unit to the at least one reserve bus concurrent with the first UPS unit being coupled to a first load via a first load bus. | 03-28-2013 |
20130116946 | METHODS AND APPARATUS FOR DETERMINING POWER DISTRIBUTION SYSTEM TOPOLOGY USING DISTURBANCE DETECTION - A disturbance, for example, a frequency variation, is generated in at least a portion of the power distribution network. The disturbance may be generated, for example, by an uninterruptible power supply (UPS) or some other component of the power distribution network, such as a switch. At least one node of the network experiencing the disturbance is identified and a topology of the power distribution network is determined responsive to identifying the at least one node. The at least one node may be identified by detecting a voltage-related artifact corresponding to the disturbance. A phase-locked loop (PLL)—based circuit may be used for fast artifact detection. Groups of devices in the network may be identified from the artifacts, and combinatorial optimization techniques may be used to determine connectivity within such groups. | 05-09-2013 |
20130155729 | SYSTEM AND METHOD FOR DETECTING PHASE LOSS AND DIAGNOSING DC LINK CAPACITOR HEALTH IN AN ADJUSTABLE SPEED DRIVE - A system and method for detecting input phase loss in an adjustable speed drive (ASD) includes an input unit to detect operating data from the ASD. The operating data includes a DC link current of the ASD. The system also includes a state observer that is adapted to receive the operating data from the input unit and extract a DC link capacitor current of the ASD using the DC link current. The system also includes a controller programmed to compare the extracted DC link capacitor current to a predetermined fault range and generate a fault indication of an input phase loss if the extracted DC link capacitor current is within the predefined fault range. The controller is also programmed to calculate an estimated lifespan of the DC link capacitor based on the extracted DC link capacitor current. | 06-20-2013 |
Patent application number | Description | Published |
20130194844 | Closed Loop Control of a Cyclo-Converter - A three-phase resonant cyclo-converter including a closed loop control module for controlling the switching frequency of the cyclo-converter, the closed loop control module including: a voltage signal development module arranged to develop a voltage signal representative of a voltage output waveform of the cyclo-converter, a storage module arranged to accumulate voltage signal values for phase portions of the voltage output waveform, where the voltage signal values are based on a voltage error signal and accumulated historical voltage signal values for the same corresponding phase portions, and a switching frequency control module arranged to develop a switching frequency control signal to control the switching frequency of the cyclo-converter based on the accumulated voltage signal values for corresponding phase portions of the voltage output waveform, and a proportional voltage signal based on a difference between the developed voltage signal and a reference voltage signal. | 08-01-2013 |
20130194850 | Feed Forward Control for a Cyclo-Converter - A three-phase resonant cyclo-converter, the cyclo-converter comprising a feed forward control module arranged to develop a feed forward signal for controlling a switching frequency of the cyclo-converter dependent on conditions of a power supply arranged to provide power to the cyclo-converter. | 08-01-2013 |
20130201738 | POWER FACTOR CONTROL OF A CYCLO-CONVERTER - A three-phase resonant cyclo-converter comprising a power control module, wherein the power control module is arranged to develop a plurality of repeating switching periods within a cycle, the power control module further arranged to: control the length of a first switching period in the cycle to adjust the power flow, and control the relative length of two or more further switching periods in the cycle to adjust the power factor, wherein the relative length is controlled based on a cross-product of voltage and current values associated with the further switching periods. | 08-08-2013 |
Patent application number | Description | Published |
20130204263 | Systems and Methods For Delivering Bone Cement to A Bone Anchor - A method of stabilizing a first vertebra and a second vertebra includes implanting a first bone anchor into the first vertebra, implanting a second bone anchor into the second vertebra, connecting a first anchor connection instrument to the first anchor, connecting a second anchor connection instrument the second anchor, positioning a cement delivery tube into a passage provided through the first anchor, delivering bone cement from a bone cement delivery system coupled to the bone cement delivery tube through the passage in the first anchor to the first vertebra, removing the cement delivery tube from the first anchor connection instrument and the first anchor, connecting the cement delivery tube to second anchor connecting instrument connected to the second anchor, delivering bone cement through a passage in the second anchor to the second vertebra, connecting a spinal connection element to the first anchor and the second anchor. | 08-08-2013 |
20140058515 | SURFACE EXPANDING SPACER - An interbody spacer comprising a series of stacked walls connected by a common base, wherein the spacer collapses when pressed into an access delivery tube. During insertion, the walls can flex as a unit, like bending a deck of cards, to traverse bends in the access tube. Upon distally exiting the portal of the access delivery tube, the walls track apart (like spreading fingers) to create a wide base of support for the vertebral body endplate. A graft delivery device that uses a conveyor belt-type approach to deliver bone graft from the device to a location in a patient. In some embodiments, the conveyor-belt is manually actuated. | 02-27-2014 |
20140378980 | Cortical Rim-Supporting Interbody Device - A central inflatable distractor and a perimeter balloon are inserted into the disc space in uninflated configurations. The central inflatable distractor is then expanded, thereby distracting the vertebral endplates to the controlled height of the central inflatable distractor. The perimeter balloon is then inflated with a curable substance. The perimeter balloon expands as it is filled with the curable substance and conforms to the void remaining in the disc space around the central inflatable distractor, thereby creating a horseshoe shape. Once the flowable material in the perimeter balloon has cured, the central inflated distractor can be deflated and removed. The remaining void (or inner space) is then packed with graft for fusion. | 12-25-2014 |