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Kentaro Kogure

Kentaro Kogure, Shiga JP

Patent application numberDescriptionPublished
20100292454NEURONAL REGENERATION PROMOTING AGENT - It is an object of the present invention to provide a novel neuronal regeneration promoting agent, particularly a neuronal regeneration promoting agent having an inhibitory effect on glial scar formation. The present invention provides a neuronal regeneration promoting agent which comprises an inhibitor of a bone morphogenetic protein type 1A receptor (BMPR1A) as an active ingredient.11-18-2010

Kentaro Kogure, Hokkaido JP

Patent application numberDescriptionPublished
20090136563Method for Coating Particle with Lipid Film - A method for coating an object, i.e. a particle, with two sheets of lipid film having a space formed there between. In the method for coating a particle having a positive electrostatic-charging property with two sheets of lipid film, the particle having a positive electrostatic-charging property is brought into contact with a plurality of SUV type liposomes having a negative electrostatic-charging property to form a complex having a negative electrostatic-charging property containing the particle having a positive electrostatic-charging property and the SUV type liposomes having a negative electrostatic-charging property coupled electrostatically with the particle having a positive electrostatic-charging property, and then the complex having a negative electrostatic-charging property is treated with cation.05-28-2009
20090305409Liposome Capable of Effective Delivery of Given Substance Into Nucleus - Disclosed is a non-viral vector capable of delivering a given substance into the nucleus of a target cell effectively even when the target cells is a undividable cell such as a dendritic cell. A bilamellar liposome having a first lipid membrane and a second lipid membrane successively from the outside, the first lipid membrane having a membrane-fusing ability and the second lipid membrane having on its surface a nuclear transport peptide.12-10-2009
20100104623AGENT FOR ENHANCING THE RESISTANCE OF LIPOSOME AGAINST BIOLOGICAL COMPONENT, AND LIPOSOME MODIFIED WITH THE AGENT - It is intended to provide a positively charged liposome, particularly having a polyarginine peptide on a surface thereof, which is capable of increasing the resistance to a negatively charged biological component such as a protein in the blood and maintaining a high ability to deliver a substance even in the blood. An agent for enhancing the resistance of liposome against biological component comprising a peptide having at least one of the following characteristics (a) and (b) as an active ingredient: 04-29-2010
20100136099LIPOSOME FOR INDUCTION OF CELL-MEDIATED IMMUNITY - Disclosed is a liposome which includes an antigenic substance therein and has, on its surface, a peptide containing several contiguous arginine residues. The liposome enables an antigen-presenting cell to achieve the selective antigen presentation through an MHC Class-I molecule, and can induce a cell-mediated immunity specifically. The liposome can also induce the antigen presentation by a matured dendritic cell.06-03-2010
20100166840LIPOSOME HAVING LIPID MEMBRANE CONTAINING BACTERIAL CELL COMPONENT - The object is to provide a liposome by which a bacterial cell component insoluble in water and an organic solvent (e.g., BCG-CW) can be pharmaceutically prepared in a form applicable to a living body (i.e., a form in which the bacterial cell component can be dispersed in an aqueous solvent and has a controlled size) without using any surfactant. Disclosed is a liposome having a lipid membrane containing a bacterial cell component insoluble in water and an organic solvent (e.g., BCG-CW).07-01-2010

Patent applications by Kentaro Kogure, Hokkaido JP

Kentaro Kogure, Kita-Ku JP

Patent application numberDescriptionPublished
20100143482METHOD OF PRODUCING MICROCAPSULES - It is intended to provide a method whereby various kinds of microcapsules, which are usable in, for example, a gene vector, can be produced in a small amount. This production method comprises: feeding a fluid containing a substance to be encapsulated into at lease one (06-10-2010

Kentaro Kogure, Kyoto JP

Patent application numberDescriptionPublished
20090221953COMPOSITION COMPRISING PROTEIN-LIPOSOME COMPLEX FOR IONTOPHORESIS - Provided is a composition for iontophoresis comprising a negatively-charged protein-liposome complex, in which the protein-liposome complex is formed of a negatively-charged protein and a cationic liposome. Such may provide a composition capable of efficiently delivering a protein having a large molecular weight intradermally and inducing an immune response effectively by iontophoresis.09-03-2009
20090234271COMPOSITION COMPRISING siRNA-POLYCATION COMPLEX FOR IONTOPHORESIS - To provide a composition which is capable of efficiently delivering an siRNA intradermally and of effectively suppressing the expression of a target gene by an RNAi. Provided is a composition for iontophoresis including an siRNA-polycation complex which is charged negatively.09-17-2009

Kentaro Kogure, Sapporo JP

Patent application numberDescriptionPublished
20080208106METHODS OF PREDICTING DOSE OF DRUG AND PROGRAM FOR PREDICTING DOSE OF DRUG - A migration M of a drug ion in a membrane type iontophoresis device for administering the drug ion through a first ion exchange membrane is predicted on the basis of a migration C of the drug ion from the first ion exchange membrane to the outside of the device in the case where a voltage is applied to an electrode by using the device under such a condition that the first ion exchange membrane is not brought into contact with the skin of a living organism and a migration R of the drug ion to a liposome caused by mixing a liposome solution having a predetermined concentration and a drug solution containing a predetermined concentration of the drug ion.08-28-2008
20090022784SYSTEMS, DEVICES, AND METHODS FOR IONTOPHORETIC DELIVERY OF COMPOSITIONS INCLUDING LIPOSOME-ENCAPSULATED INSULIN - Systems, devices, and methods for delivering one or more active ingredients to intradermal tissues, deep regions of pores, and intradermal tissues in the vicinity of pores. In some embodiments, a composition is provided including a plurality of liposomes including a cationic lipid, and an amphiphilic glycerophospholipid having a saturated fatty acid moiety and an unsaturated fatty acid moiety, and at least one insulin, insulin analog, or insulin derivative.01-22-2009

Kentaro Kogure, Tokyo JP

Patent application numberDescriptionPublished
20120105702VIDEO PROCESSING APPARATUS, IMAGING APPARATUS, VIDEO PROCESSING METHOD, AND STORAGE MEDIUM - A video processing method includes calculating mean values with respect to x coordinate value and y coordinate value of vertices that define a corresponding area, which is obtained when a designated area in spherical coordinates is projected on an xy coordinate plane that represents a captured image, and superimposing a mask image R on the captured image in such a way as to bring a point G having an x coordinate value and a y coordinate value identical to the calculated mean values with respect to the x coordinate value and the y coordinate value into coincidence with a point defined by a midpoint in the height direction and a midpoint in the width direction of the mask image.05-03-2012