| Patent application number | Description | Published |
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| 20080255348 | METHOD FOR THE PREPARATION OF AN ENANTIOMER OF A TETRACYCLIC BENZAZEPINE - The present invention relates to a method for the preparation of mirtazapine and tetracyclic analogous compounds having substantial enantiomeric excess of the R or S form. The invention further relates to a novel intermediate and its use for the preparation of mirtazapine having a substantial enantiomeric excess of the R or S form. The method comprising the steps of a: providing a carboxylic acid compound according to Formula I having a substantial enantiomeric excess of the R or S form, b: converting the carboxylic acid group of compound I into a ketone group, producing a ketone compound of Formula II, c: optionally reducing ketone compound II with a mild reduction agent to form the intermediate hydroxy compound of Formula III and d: forming the mirtazapine of Formula IV by reduction of the ketone compound II or of the hydroxy compound III using a strong reduction agent. | 10-16-2008 |
| 20080255349 | METHOD FOR THE PREPARATION OF AN ENANTIOMERICALLY PURE BENZAZEPINE - The invention relates to a method for the preparation of a cyclic compound according to formula III comprising reacting a compound according to Formula I and a compound according to formula II, | 10-16-2008 |
| 20090227803 | PROCESS FOR THE PREPARATION OF ASENAPINE AND INTERMEDIATE PRODUCTS USED IN SAID PROCESS - The invention relates to a novel process for the preparation of asenapine, i.e. trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, as well as to novel intermediate products for use in said process. | 09-10-2009 |
| 20100036126 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE - This invention provides for a compound according to Formula (1), wherein R | 02-11-2010 |
| 20100152461 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF TRANS-5-CHLORO-2-METHYL-2,3,3A,12B-TETRAHYDRO-1H-DIBENZ[2,3:6,7]-OXEPINO[- 4,5-C]PYRROLE - Disclosed are novel amino acid derivatives of formula (I) and (II) | 06-17-2010 |
| 20100234618 | Process for the Preparation of Asenapine and Intermediate Products Used in Said Process - The invention relates to a novel process for the preparation of asenapine, i.e. trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, as well as to novel intermediate products for use in said process. | 09-16-2010 |
| 20110166363 | PROCESS FOR THE PREPARATION OF ASENAPINE AND INTERMEDIATE PRODUCTS USED IN SAID PROCESS - The invention relates to a novel process for the preparation of asenapine, i.e. trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, as well as to novel intermediate products for use in said process. | 07-07-2011 |
| Patent application number | Description | Published |
|---|
| 20080292867 | Method for Manufacturing a Fire Retardant Composite and Composite Thus Obtained - The present invention relates to a method of manufacturing a fire retardant composite, a composite of a foamed polymer having a coating with fire retardant properties, and also the use of such composites. The method according to the present invention comprises the following steps: i) providing beads of foamed polymer, ii) applying a coating on the beads of step i) and iii) shaping the thus coated beads into said composite. | 11-27-2008 |
| 20090000518 | Aqueous Aluminosilicate Gel-Forming Composition - An aqueous gel-forming composition, e.g. a fire retardant coating composition, comprises an aluminosilicate and an organic liquid having a boiling point greater than 110° C., e.g. silicone oil, which enhances the integrity of films formed by application of the composition as a coating to a surface then followed by drying. | 01-01-2009 |
| 20100018142 | METHOD OF MANUFACTURING A FIRE RETARDANT COMPOSITE, A COMPOSITE AND ITS USE - A method of manufacturing a fire retardant composite, a composite and its use. A method of manufacturing a fire retardant composite by applying an aqueous gel-forming composition, e.g. a fire retardant coating composition, on a substrate comprises an aluminosilicate, the aluminosilicate comprising alkali metal aluminate and an alkali metal silicate, and an organic liquid having a boiling point greater than 110° C., e.g. silicone oil. The molar ratio of SiO | 01-28-2010 |
