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Keefe, US
Anthony Dominic Keefe, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080214489 | Aptamer-mediated intracellular delivery of oligonucleotides - Compositions and methods to mediate the intracellular and sub-cellular delivery of therapeutic, diagnostic and imaging agents, such as oligonucleotides. The compositions of the invention include nucleic acid conjugates comprising a delivery aptamer that is connected to an oligonucleotide. The delivery aptamer may be connected directly to the oligonucleotide, or may be connected indirectly to the oligonucleotide, such as through a linker. The oligonucleotide may be either a therapeutic, diagnostic or imaging oligonucleotide. The methods of the invention are used to increase potency, or alter distribution, half-life, metabolic fate, toxicity and other characteristics. | 09-04-2008 |
| 20090081679 | Compositions and methods for in vivo SELEX - The invention describes methods for the in vivo selection of oligonucleotides, preferably aptamers, that persist in biological compartments. In one embodiment, the biological compartment comprises at least one tissue which, in a preferred embodiment, is the blood within the circulatory system of a living mammal. The invention also contemplates oligonucleotides, preferably aptamers, selected through in vivo SELEX that may be linked to therapeutic or diagnostic compositions including other oligonucleotides. | 03-26-2009 |
| 20100120024 | Materials and methods for the generation of transcripts comprising modified nucleotides - Materials and Methods are provided for producing aptamer therapeutics having modified nucleotide triphosphates incorporated into their sequence. | 05-13-2010 |
Dan Keefe, Acworth, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20100059512 | Microwave interactive display package - Various microwave energy interactive display packages, blanks for forming such packages, and methods of displaying and heating a food item are provided. | 03-11-2010 |
Daniel Keefe, Acworth, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20090078698 | Microwavable food package having an easy-open feature - A system for heating a food item in a microwave oven is provided. The system may comprise an inner container and an outer carton including an opening feature that allows for easy opening thereof. The system also may include a microwave energy interactive element. | 03-26-2009 |
Daniel J. Keefe, Cincinnati, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20110168698 | Construct for Supporting Food Items - A construct for supporting a food item comprises a plurality of divider walls and a plurality of base panels. The divider walls are spaced from one another along a length of the construct. Each base panel is located between a pair of adjacent divider walls and connecting the adjacent divider walls. A microwave energy interactive element may overlie a surface of the construct. | 07-14-2011 |
David Keefe, Wilton, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090114144 | Interactive Bookmark Device - An interactive, novelty bookmark device includes a composite frame having a front and back cover, a magnetic drawing screen mounted within the composite frame, wherein a portion of the drawing screen is accessible through a window in the front cover for receipt and persistent display of information input by a user of the device, a stylus having a magnetic tip and configured for use by the user to input information onto the magnetic drawing screen, an erase lever slidably mounted within the composite frame and having a magnet disposed thereon to selectively erase the magnetic drawing screen, and an engagement appendage mounted to and extending from the frame for releasably securing the interactive bookmark device to associated printed reading material which needs to be bookmarked. | 05-07-2009 |
David L. Keefe, Newport, RI US
| Patent application number | Description | Published |
|---|---|---|
| 20090326316 | METHODS OF ASSESSING THE RISK OF REPRODUCTIVE FAILURE BY MEASURING TELOMERE LENGTH - The invention features a method of identifying oocytes with a risk of reproductive failure and/or aneuploidy based on a telomere length assay. | 12-31-2009 |
Gary Keefe, Brecksville, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20100114951 | MEDICAL IMAGE IMPORTER AND METHOD - Provided are a medical information importer and method for importing medical information into a network-accessible database. The medical information importer includes a housing includes with an external stand-alone form factor, the housing including an interface for receiving a portable computer-readable medium storing medical information. An information reading component is provided for reading the medical information from the portable computer-readable medium when operatively connected to the interface. A computer-readable memory in communication with the information reading component stores, at least temporarily, the medical information read by the reading component under the direction of a controller. And a network interface connects the medical information importer to a communication network without a local connection between the medical information importer and a computer terminal including a display device for viewing the medical information. | 05-06-2010 |
| 20110161112 | MEDICAL DATA STORAGE SERVER - Provided is a method of documenting a medical procedure including receiving medical data captured during the medical procedure to be documented. Information indicative of an identity of at least one of a patient that is a subject of the medical procedure and a physician involved with the medical procedure is received. The medical data is stored in a non-transitory computer readable medium associated with the at least one of the patient and the physician. Access to the medical data stored on the computer readable medium is restricted, allowing the physician involved with the medical procedure to subsequently retrieve the medical data stored in the computer readable medium and view the medical data retrieved. Restricting access to the recorded medical data prevents another physician, who may not have been involved in the medical procedure, from viewing the medical data without first entering information indicative of authorization to view the medical data. | 06-30-2011 |
Gary W. Keefe, Brecksville, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20090296540 | MEDICAL DISC PUBLISHER - A method and apparatus for storing on a portable computer-readable medium, a study comprising at least one medical output produced by a medical modality and formatted in a standard medical format used by specialized computers configured for viewing outputs produced by medical modalities, and optionally labeling the portable computer-readable medium. The method includes receiving a transmission comprising the medical output that is formatted according to the standard medical format, at least temporarily storing the medical output as it is received in a buffer memory to be subsequently stored onto the portable computer-readable medium, and storing the medical output from the buffer memory onto the portable computer-readable medium. | 12-03-2009 |
| 20120019840 | DEFAULT MEDIA SELECTION METHODS IN A MULTI-MEDIA PRINTER - A multi-media print includes a decoding module, a configuration memory, and a parameter determination module. The decoding module decodes print job parameters and print job data, and outputs decoded print job parameters including decoded print job media selection parameters and the decoded print job data. The configuration memory stores default configuration parameters. The parameter determination module receives the decoded print job parameters including the decoded print job media selection parameters and the decoded print job data and also receives the default configuration parameters including the default media selection parameters from the configuration memory. The parameter determination module determines the final print job media selection parameters for the print job, utilizing the decoded print job media selection parameters and the default media selection parameters. The default media selection parameters are utilized when the print job parameters and print job data are not sufficient to select the media. | 01-26-2012 |
Jack Edward Keefe, Sanford, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20120090114 | Electrical Terminal Connector Cleaning Device and Method - An electrical connector cleaning devices includes a first elongate cleaning element extending outwardly from a housing, wherein the first cleaning element includes raised surface portions extending radially outward from its outside wall surface. A second elongate cleaning element extends outwardly from the housing and includes raised surface portions extending radially inward from its inside wall surface. Each of the first and second cleaning elements is a cylindrical tube having a longitudinally extending open seam forming a gap for permitting a flexing of the cleaning element walls through a biasing force placed thereon. Each of the raised surface portions forms rings extending around the inside and outside wall surfaces of the first and second cleaning elements, respectively. One ring has its raised surface portions angularly offset along the longitudinal direction from an adjacent raised surface portion in an adjacent ring of raised surface portions. | 04-19-2012 |
James Augustus Keefe, O'Fallon, MO US
| Patent application number | Description | Published |
|---|---|---|
| 20080237371 | POWER SPRAYER - The present invention is a dispenser adapted to be coupled to a fluid container. The dispenser comprises a dispensing head, an energy source, and a fluid pathway. The dispensing head includes a fluid pump, a motor adapted to power the pump, a trigger adapted to control the motor, and a nozzle orifice in fluid communication with a discharge end of the pump. The fluid pathway has one portion in fluid communication with an intake end of the pump and another portion inside the container. | 10-02-2008 |
James J. Keefe, Winchester, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080302229 | Conical piccolo - The subject invention is an improved conical piccolo comprising various new fingering mechanisms and configurations, as well as an additional tone hole opening. The improved conical piccolo allows a user to easily play all six standard trills produced by the cylindrical flute fitted with the c sharp trill key, including the third octave G to A trill. Moreover, the improved conical piccolo simplifies the fingering required by a user to play the third octave G to A trill. Moreover, the subject invention allows the user of piccolo to play two additional trills, namely the first and second octave C to D trills, with improved intonation and response. | 12-11-2008 |
James M. Keefe, Penn Valley, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090054796 | Patient Screening Tools for Implantable Cardiac Stimulus Systems - Tools and devices are provided for determining whether a patient is well suited to receiving an implantable cardiac stimulation device by analyzing cardiac signals captured using external or cutaneous electrodes. Some of the illustrative tools include shapes for visual comparison to printed ECG strips. Automatic devices are also disclosed which perform at least some analytical functions electronically for a user. In an example, a printed ECG strip is visually compared to a shape in order to ensure a patient is well suited to receiving a cardiac stimulation device having a particular implant location and/or cardiac signal analysis method implementation. | 02-26-2009 |
| 20110178564 | Dynamically Filtered Beat Detection in an Implantable Cardiac Device - Methods and implantable devices that detect cardiac events using dynamic filtering. Illustratively, default filtering is performed except for a predefined period of time following detection of cardiac events, during which post-beat filtering is performed instead. The example post-beat filtering applies a narrower pass-band to the signal than the default filtering in order to attenuate T-waves more greatly than the default filtering during a time period after a detected event that is expected to correspond to occurrence of T-waves. | 07-21-2011 |
| 20120071773 | Patient Screening Tools for Implantable Cardiac Stimulus Systems - Tools and devices are provided for determining whether a patient is well suited to receiving an implantable cardiac stimulation device by analyzing cardiac signals captured using external or cutaneous electrodes. Some of the illustrative tools include shapes for visual comparison to printed ECG strips. Kits for use of illustrative tools are also shown. Automatic devices are also disclosed which perform at least some analytical functions electronically for a user. In an example, a printed ECG strip is visually compared to a shape in order to ensure a patient is well suited to receiving a cardiac stimulation device having a particular implant location and/or cardiac signal analysis method implementation. | 03-22-2012 |
Kevin Keefe, Brentwood, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20090243370 | WHEEL WEIGHT - A wheel weight segment for use on a wheel including a rim, having a body with a top surface, a bottom surface, a first side and a second side disposed opposite the first side. A top lip portion with a top surface extends outwardly from the first side of the body and a bottom lip portion with a bottom surface extends outwardly from the second side of the body. The top surface of the body and the top surface of the top lip portion lie in a first plane, and the bottom surface of the body and the bottom surface of the bottom lip portion lie in a second plane. | 10-01-2009 |
Melinda H. Keefe, Midland, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100317753 | PROCESS OF HEAT TREATING STRUCTURED POLYMER PARTICLES - A process comprising heating an aqueous dispersion of first structured polymer particles at a temperature of at least about 155° C., optionally in the presence of a base and/or a swelling agent, to produce an aqueous dispersion of heat treated structured polymer particles. | 12-16-2010 |
Melinda H. Keefe, Willow Grove, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20120058278 | STABLE AQUEOUS COMPOSITE COMPOSITIONS - This invention provides a method for forming a stable aqueous composition including composite particles by admixing TiO2 particles and adsorbing emulsion polymer particles at or below the critical composite ratio to an equilibrated viscosity range of from 200 cps to 4000 cps. Also provided is a method for forming a stable aqueous composition including composite particles by admixing TiO2 particles and adsorbing emulsion polymer particles at a mixing intensity of greater than 2 hp/kgal. A method for providing a coating including composite particles is also included. | 03-08-2012 |
Michael Keefe, West Melbourne, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20100259448 | METHOD AND SYSTEM FOR HEALTH MONITORING OF AN OVER THE AIR GEO-LOCATION SYSTEM - A method for testing each one of a plurality of receiving sites operative in a time difference of arrival geo-location system. The method comprises determining a theoretical time of arrival of a test message at each receiving site assuming the test message was transmitted from a test message transmitting antenna at a known location; determining a measured time of arrival of the test message at each receiving site, the test message transmitted from the test message transmitting antenna; determining a true time of arrival of the test message at each receiving site, the true time of arrival comprising the measured time of arrival less a start time of the test message; determining a difference between the theoretical and the true times of arrival for each receiving site, wherein the difference for each receiving site is indicative of a health of the receiving site. | 10-14-2010 |
| 20110319029 | METHOD AND SYSTEM FOR DIAGNOSING RADIO PERFORMANCE DURING FUNCTIONAL OVER-THE-AIR OPERATION - An apparatus for determining a health of radio-frequency transmitters each transmitting a transmitted signal during normal operation. The apparatus comprises a receiver for receiving received signals, each received signal responsive to a transmitted signal, a first element for determining signal parameters of each received signal, the signal parameters responsive to an operating condition of a transmitter, each transmitted signal and each associated received signal including an identifier of the transmitter that transmitted the transmitted signal, the apparatus using the identifier to link determined signal parameters with the transmitter that transmitted the transmitted signal and a second element for determining a health of the transmitter that transmitted the transmitted signal, the health responsive to a relationship between one or more signal parameters and a selected value or a range of selected values for each signal parameter. | 12-29-2011 |
Michael Keefe, Melbourne, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20110090807 | Method and System for Analyzing Radio Performance During Over-the-Air Operation - An apparatus for determining operating characteristics of radio-frequency (RF) transmitting devices while the devices are in normal operation transmitting over-the-air RF signals. The apparatus comprises at least one signal sensor for receiving the RF signals, each sensor responsive to the RF signals received at a plurality of antennas or received at a directional antenna, an analyzer for determining signal parameters of received RF signals and for determining operating characteristics of the transmitting devices from the signal parameters, wherein each RF signal includes an identifier of the transmitting device, the apparatus using the identifier to link operating characteristics determined from the RF signals to the transmitting device, and a graphical user interface for displaying the operating characteristics for each transmitting device. | 04-21-2011 |
Michael Keefe, Bear, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20100154621 | Ballistic Resistant Fabric Armor - A woven ballistic resistant fabric armor system comprising at least one ply having a yarn-yarn angle between the warp and fill yarns of less than 90°, with each ply oriented relative to an axis along the thickness of the plies such that adjacent plies have a different yarn-yarn angle, a different orientation, or both. The armor system may feature materials of different stiffness, strength, and strain-to-failure in each ply or a filler between selected plies, including a filler comprising discrete pieces of fabric ply that fit within the cell periphery of a stitching pattern. | 06-24-2010 |
Mike Keefe, Melbourne, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20080203107 | Patient controlled timed medication dispenser - A medication on demand dispenser. The dispenser provides patient access to medications prescribed to be available on an as-needed basis but with a prescribed minimum time interval between doses. The dispenser permits access to a single medication dose after each minimum time interval has elapsed. After a drug dose is presented to the patient, the dispenser prevents access to the next dose until the minimum time interval has elapsed. | 08-28-2008 |
Robert Paul Keefe, Alpharetta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20100156632 | INFRASTRUCTURE MONITORING SYSTEM AND METHOD - An infrastructure monitoring system and method that comprises multiple monitoring devices and/or multiple output devices. Each monitoring device includes at least one sensor for collecting data, a data storage device for storing the data, a processor for analyzing the data, and a communications device for transmitting and receiving data. The system may also include an operations center for controlling and receiving data from the plurality of devices. | 06-24-2010 |
| 20100295672 | INFRASTRUCTURE MONITORING DEVICES, SYSTEMS, AND METHODS - An infrastructure monitoring system and method that comprises multiple communications devices. At least one communications device is coupled to an element of the infrastructure. | 11-25-2010 |
| 20110308638 | INFRASTRUCTURE MONITORING DEVICES, SYSTEMS, AND METHODS - An infrastructure monitoring system and method include multiple communications devices. At least one communications device is coupled to an element of the infrastructure. | 12-22-2011 |
Rod Keefe, Jacksonville, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20110297752 | PROCESS AND APPARATUS FOR RAIL RESTORATION AND RAIL MANUFACTURE USING WELDING - A method for restoring a worn rail section includes cleaning a worn surface of a rail section to expose a clean metal surface, heating the rail section to a first temperature before welding, welding new metal on the clean metal surface of the rail section after heating the rail section to the first temperature, heating the rail section to a second temperature after the welding to heat-treat a heat-affected area caused by the welding, and shaping the rail section, wherein the welding is performed by a gas metal arc welding (GMAW) process. | 12-08-2011 |
Thomas J. Keefe, Methuen, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100168502 | MODULAR NEONATAL INTENSIVE CARE SYSTEM - A modular neonatal intensive care system including an infant incubator, bassinet and frame is provided. The infant incubator of the present disclosure is configured for reducing the overall cost and/or minimizing the amount of power that the neonatal care system or infant incubator draws. A number of the features also make the design more appropriate for the conditions in developing countries. The neonatal care system is also integrated with a hospital bassinet which is made up of a bassinet bed and a frame. The frame for the bassinet acts as both a structural support system and a means for transportation when the neonatal care incubator is attached at the top of the frame. | 07-01-2010 |