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Keast, CA

Thomas Keast, Mountain View, CA US

Patent application numberDescriptionPublished
20090069797BIPOLAR DEVICES FOR MODIFICATION OF AIRWAYS BY TRANSFER OF ENERGY - This relates to a device for treating lung disease, and more particularly, relates to a device for exchanging energy with airway tissue such as that found in the airways of human lungs. The exchange of energy with this airway tissue in the airways reduces the ability of the airways to constrict and/or reduces the resistance within the airway to the flow of air through the airway.03-12-2009
20090112203MODIFICATION OF AIRWAYS BY APPLICATION OF MICROWAVE ENERGY - Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung. The damaging of lung cells, damaging tissue, causing trauma, and destroying airway smooth muscle tone with the apparatus may be any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.04-30-2009
20090143705MODIFICATION OF AIRWAYS BY APPLICATION OF ULTRASOUND ENERGY - Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung. The damaging of lung cells, damaging tissue, causing trauma, and destroying airway smooth muscle tone with the apparatus may be any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.06-04-2009
20100185190METHODS FOR TREATING ASTHMA DAMAGING NERVE TISSUE - A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.07-22-2010
20100204689METHOD FOR TREATING AN ASTHMA ATTACK - A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.08-12-2010
20110079230METHOD FOR TREATING AN ASTHMA ATTACK - A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.04-07-2011

Patent applications by Thomas Keast, Mountain View, CA US

Thomas Keast, San Jose, CA US

Patent application numberDescriptionPublished
20090143776MODIFICATION OF AIRWAYS BY APPLICATION OF CRYO ENERGY - A method for decreasing responsiveness or decreasing resistance to airflow of airways involves the transfer of energy to or from the airway walls to prevent or reduce airway constriction and other symptoms of lung diseases. The treatment reduces the ability of the airways to contract during an acute narrowing of the airways, reduces mucus plugging of the airways, and/or increases the airway diameter. The methods according to the present invention provide a longer duration and/or more effective treatment for lung diseases than currently used drug treatments, and obviate patient compliance issues.06-04-2009

Thomas Keast, Sunnyvale, CA US

Patent application numberDescriptionPublished
20110251592DEVICES FOR MAINTAINING SURGICALLY CREATED OPENINGS - Devices and methods are directed to improving the gaseous exchange in a lung of an individual having, for instance, chronic obstructive pulmonary disease. More particularly, conduits may be deployed in the lung to maintain collateral openings (or channels) surgically created through airway walls. This tends to facilitate both the exchange of oxygen ultimately into the blood and decompress hyper-inflated lungs. The conduit includes a radially expandable center section having a first end, a second end, and a passageway extending from the first end to the second end. A control segment may be associated with the conduit to limit the degree of radial expansion. The conduit further includes a plurality of deflectable members extending from the ends of the center section. A tissue barrier may coaxially surround the conduit such that tissue ingrowth is prevented. The conduits may also include hold-down members and bioactive coatings that serve to prevent ejection of the conduit as well as prevent narrowing of the passageway due to tissue ingrowth.10-13-2011

Thomas M. Keast, Sunnyvale, CA US

Patent application numberDescriptionPublished
20090124883AIRWAY BYPASS SITE SELECTION AND TREATMENT PLANNING - This invention relates to systems and methods for site selection and placement of extra-anatomic passages altering gaseous flow in a diseased lung.05-14-2009
20090143678DEVICES FOR CREATING PASSAGES AND SENSING BLOOD VESSELS - Devices and methods are disclosed for creating passages in tissue and detecting blood vessels in and around the passages. The devices may be used to create channels for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having Chronic Obstructive Pulmonary Disease (COPD). In addition, the devices may be used to sample tissue during biopsy or other medical procedures where perforating a blood vessel could result in injury to a patient.06-04-2009
20090204005PUNCTURE RESISTANT CATHETER FOR SENSING VESSELS AND FOR CREATING PASSAGES IN TISSUE - Devices and methods are disclosed for providing a sensing element to scan tissue and detect the presence of structures within the tissue to avoid the structures when performing a procedure on the tissue. A tissue penetrating member or needle is extendable from the device to create a channel or opening through the wall of an airway. The device is sufficiently flexible to navigate turns of at least 90 degrees. The distal section of the device includes puncture resistant sections, a curved needle tip, and depth limiting features that serve to create a channel in the lumen wall without causing collateral damage to the instruments, or patient.08-13-2009
20090275840BLOOD VESSEL SENSING CATHETER HAVING WORKING LUMEN FOR MEDICAL APPLIANCES - Devices and methods are disclosed for providing a sensing element to scan tissue and detect the presence of structures within the tissue to avoid the structures when performing a procedure on the tissue. A catheter includes a blood vessel sensing assembly and a working lumen adapted to receive a medical appliance or instrument for performing various medical procedures.11-05-2009
20090287087DEVICES FOR CREATING PASSAGES AND SENSING FOR BLOOD VESSELS - Devices and methods are disclosed for creating passages in tissue and detecting blood vessels in and around the passages. The devices may be used to create opening in tissue without removing a sensing assembly from the tissue. The devices herein may be used for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having Chronic Obstructive Pulmonary Disease (COPD). In addition, the devices may be used to sample tissue during biopsy or other medical procedures where perforating a blood vessel could result in injury to a patient.11-19-2009
20100305463AIRWAY BYPASS SITE SELECTION AND TREATMENT PLANNING - This invention relates to systems and methods for site selection and placement of extra-anatomic passages altering gaseous flow in a diseased lung.12-02-2010
20100312141TISSUE SAMPLING DEVICES, SYSTEMS AND METHODS - Methods, devices, and systems are described herein that allow for improved sampling of tissue from remote sites in the body. A tissue sampling device comprises a handle allowing single hand operation. In one variation the tissue sampling device includes a blood vessel scanning means and tissue coring means to excise a histology sample from a target site free of blood vessels. The sampling device also includes an adjustable stop to control the depth of a needle penetration. The sampling device may be used through a working channel of a bronchoscope.12-09-2010
20110146673METHODS FOR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE - The methods and devices disclosed altering gaseous flow within a lung to improve the expiration cycle of individuals having Chronic Obstructive Pulmonary Disease.06-23-2011

Patent applications by Thomas M. Keast, Sunnyvale, CA US