Patent application number | Description | Published |
20100173288 | SERUM/PLASMA MICRONAS AND USES THEREOF - This invention provides a combination of microRNAs for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable microRNAs stably existing in the serum/plasma of a subject; and a method for evaluating the physiological and/or pathological condition of a subject, wherein the method includes determining all detectable microRNAs stably existing in the serum/plasma of a subject; and a kit for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable microRNAs that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable microRNAs stably existing in the serum/plasma of a subject. The aforementioned combination, method, kit and biochip can be used for diagnosis as well as differentially diagnosis of diseases including various tumors; various acute/chronic infectious diseases, e.g. viral diseases such as viral influenza, viral hepatitis, AIDS, SARS, bacterial diseases such as tuberculosis, bacterial pneumonia, and other acute/chronic infectious diseases caused by various pathogenic microorganisms; other acute/chronic diseases such as diseases of respiratory system, diseases of immune system, diseases of blood and hematopoietic system, diseases of circulatory system such as cardio-cerebrovascular diseases, metabolic diseases of endocrine system, diseases of digestive system, diseases of nervous system, diseases of urinary system, diseases of reproductive system and diseases of locomotor system, prediction of complications occurrence and malignant diseases relapse, evaluation of therapeutic effects, screening of pharmaceutical active ingredients, assessment of drug efficacy as well as forensic authentication and prohibited drug inspection and the like, possessing a number of advantages such as extensive detection spectrum, high sensitivity, low cost, convenience for sampling, ease for sample preservation, etc. The said method can be widely used in work related to general survey of diseases and so on, improve the low-specificity and low-sensitivity caused by individual differences which single markers are difficult to overcome, significantly increasing the clinical detection rate of diseases, all of which make it become an effective means for diagnosing diseases in an early phase. | 07-08-2010 |
Patent application number | Description | Published |
20090037990 | METHOD AND APPARATUS FOR DISTRIBUTED AUTHORIZATION BY ANONYMOUS FLEXIBLE CREDENTIAL - A method and apparatus for distributed authorization by anonymous flexible credential are provided. Pseudonym authority issues a root pseudonym to a user. The user may generate large amount of derived pseudonym from the root pseudonym. The user may obtain resource credentials from resource protectors by using derived pseudonyms. The user may select a set of resource credentials, generate a flexible credential from this set of resource credentials and request access to the resource corresponding to the set of resource credentials to a resource protector by using the flexible credential and a derived pseudonym. Revocation list for each resource may be maintained in the system such that any one of resource credentials of any user may be revoked without affecting other resource credentials of that user. | 02-05-2009 |
20090171878 | PROVABLE DATA INTEGRITY VERIFYING METHOD, APPARATUSES AND SYSTEM - The present invention proposes a Provable Data Integrity (PDI) verifying method, in which data are firstly fingerprinted at a client, and the fingerprints are sent to an archive along with the data; when necessary, the client sends a “challenge” to the archive so as to determine the integrity of the data, and the archive proves the integrity of the data by using the received fingerprints; and finally, the client verifies the integrity of the data based on the output from the archive in response to the “challenge”. | 07-02-2009 |
20090300351 | FAST SEARCHABLE ENCRYPTION METHOD - The present invention provides a method, apparatus and system for fast searchable encryption. The data owner encrypts files and stores the ciphertext to the server. The data owner generates an encrypted index according to each keyword of the files, and stores the encrypted index to the server. The index is composed of keyword item sets each being identified by a keyword item set locator and containing at least one or more file locators of the files associated with the corresponding keyword. Each file locator contains ciphertext of information for retrieval of an encrypted file and only with the correct file locator decryption key can the ciphertext be decrypted. Data owner issues a keyword item set locator as well as file locator decryption key to a searcher to enable the searcher to search on the encrypted index and retrieve files related to a certain keyword. | 12-03-2009 |
20100121856 | METHOD AND APPARATUS FOR GENERATING INDEX AS WELL AS SEARCH METHOD AND SEARCH APPARATUS - The present invention provides a method and apparatus for generating index as well as a search method and a search apparatus. Index entry comprises at least a search item identifier corresponding to a search item, one or a plurality of index items generated from one or plural pieces of search information, and an accumulator for the search information. The accumulator is generated by accumulating the search information, or accumulating ciphertext of information containing the search information, or accumulating data mapped from information containing the search information. At the time of searching, the index items and the accumulator are provided to a searcher. The searcher extracts search information from the index items and checks whether the extracted search information is complete by using the accumulator. In one embodiment, the accumulator is incorporated in an encrypted inverted index. | 05-13-2010 |
20100169321 | METHOD AND APPARATUS FOR CIPHERTEXT INDEXING AND SEARCHING - The present invention provides a method and apparatus for ciphertext indexing and searching. Indices of multiple levels are created for the encrypted files. Each item in the primary index includes a primary index item identifier and the ciphertext of the primary indexing information of the related file. The primary indexing information each includes an identifier(s) of the related secondary index item identifier(s) and the corresponding decryption information. Each item in the secondary index includes a secondary index item identifier and the ciphertext of the secondary indexing information. Information necessary for obtaining a file is included in the corresponding secondary indexing information. With the decryption information of the secondary indexing information in the decrypted primary indexing information, the ciphertext of the related secondary indexing information is decrypted so as to obtain information such as the decryption key of the file. | 07-01-2010 |
20110117565 | SERUM OR PLASMA MICRORNA AS BIOMARKERS FOR NON-SMALL CELL LUNG CANCER - The present invention provides non-small cell lung cancer markers and the use thereof. The non-small cell lung cancer markers in the present invention include at least one of the 26 selected detectable mature microRNAs existing stably in human serum or plasma. The invention also provides a probe combination, kit and biochip for detecting the non-small cell lung cancer markers. The invention further provides a method for detecting microRNAs in the serum of lung cancer patients. By detecting the variations of microRNAs in the serum of lung cancer patients, the disease can be diagnosed in vitro; the progression course of the disease can be predicted; the occurrence of complications, the rate of relapse and the prognosis of the disease can be monitored; the drug efficacy and therapeutic effects can be analyzed. The method in the present invention enables extensive detection spectrum, high sensitivity, low cost, convenient sample taking and preservation. The method can be applied in the general survey of disease, solves problems of the low specificity and sensitivity encountered with previous single markers, and increases significantly the clinical detection rate of diseases, all of which make it an effective means for diagnosing diseases at an early stage. | 05-19-2011 |
20130072393 | PANCREATIC CANCER MARKERS, AND DETECTING METHODS, KITS, BIOCHIPS THEREOF - The present invention provides microRNAs for assessing the status of pancreatic cancer in a subject, and provides methods, kits, and biochips for detecting said microRNAs. | 03-21-2013 |
20130203837 | PREPARATION OF MICROVESICLE-siRNA COMPLEXES AND USE THEREOF IN AIDS TREATMENT - The present invention provides drugs for treating AIDS, which comprises microvesicles carrying anti-HIV specific siRNA. The present invention also provides a preparation method of the drug. | 08-08-2013 |
20130209544 | MICROVESICLES CARRYING SMALL INTERFERING RNAS, PREPARATION METHODS AND USES THEREOF - Microvesicles containing interfering RNAs, preparation methods and uses thereof are provided. Pharmaceutical compositions and kits comprising the microvesicles containing interfering RNAs are also provided. Microvesicles containing interfering RNAs, pharmaceutical compositions and kits comprising such microvesicles can be used to study the effects of interfering RNAs on receptor cells. As microvesicles containing interfering RNAs can stably, high efficiently and specifically deliver interfering RNAs, microvesicles containing interfering RNAs can be used to treat related diseases. | 08-15-2013 |
20140302119 | MICROVESICLES CARRYING SMALL INTERFERING RNAS PREPARATION METHODS AND USES THEREOF - Microvesicles containing interfering RNAs, preparation methods and uses thereof are provided. Pharmaceutical compositions and kits comprising the microvesicles containing interfering RNAs are also provided. Microvesicles containing interfering RNAs, pharmaceutical compositions and kits comprising such microvesicles can be used to study the effects of interfering RNAs on receptor cells. As microvesicles containing interfering RNAs can stably, high efficiently and specifically deliver interfering RNAs, microvesicles containing interfering RNAs can be used to treat related diseases. | 10-09-2014 |
Patent application number | Description | Published |
20140121133 | SERUM/PLASMA MicroRNAs AND USES THEREOF - This invention provides a combination of microRNAs for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable microRNAs stably existing in the serum/plasma of a subject; and a method for evaluating the physiological and/or pathological condition of a subject, wherein the method includes determining all detectable microRNAs stably existing in the serum/plasma of a subject; and a kit for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable microRNAs that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable microRNAs stably existing in the serum/plasma of a subject. The aforementioned combination, method, kit and biochip can be used for diagnosis as well as differentially diagnosis of diseases including various tumors; various acute/chronic infectious diseases, e.g. viral diseases such as viral influenza, viral hepatitis, AIDS, SARS, bacterial diseases such as tuberculosis, bacterial pneumonia, and other acute/chronic infectious diseases caused by various pathogenic microorganisms; other acute/chronic diseases such as diseases of respiratory system, diseases of immune system, diseases of blood and hematopoietic system, diseases of circulatory system such as cardio-cerebrovascular diseases, metabolic diseases of endocrine system, diseases of digestive system, diseases of nervous system, diseases of urinary system, diseases of reproductive system and diseases of locomotor system, prediction of complications occurrence and malignant diseases relapse, evaluation of therapeutic effects, screening of pharmaceutical active ingredients, assessment of drug efficacy as well as forensic authentication and prohibited drug inspection and the like, possessing a number of advantages such as extensive detection spectrum, high sensitivity, low cost, convenience for sampling, ease for sample preservation, etc. The said method can be widely used in work related to general survey of diseases and so on, improve the low-specificity and low-sensitivity caused by individual differences which single markers are difficult to overcome, significantly increasing the clinical detection rate of diseases, all of which make it become an effective means for diagnosing diseases in an early phase. | 05-01-2014 |