Patent application number | Description | Published |
20090186412 | POROUS CELL SCAFFOLD AND PRODUCTION METHOD THEREOF - For easily seeding cells in its scaffold, a porous cell scaffold is produced by steps of filling a guiding solution with kinematic viscosity being 50 to 450% of that of a culture medium, in a whole continuous small hole structure having hole diameters of 5 to 3200 μm and an average hole diameter of 50 to 1500 μm, of a sheet-shaped or block-shaped scaffold having a thickness of 2 mm or more, supplying thereafter a culture medium with cells being suspended to an upper side of the scaffold, sucking the guiding solution from a lower side of the scaffold by low suction force, and entering thereby the culture medium with cells being suspended into the whole small hole structure, where a water absorber such as a filter paper is preferably used for sucking the guiding solution by low suction force. | 07-23-2009 |
20090246873 | SCAFFOLD FOR TISSUE ENGINEERING AND PRODUCTION METHOD THEREOF - To provide a scaffold for tissue engineering which consists of a bioabsorbable polymer material to be absorbed in a biotissue, and holds strength of the whole scaffold while having a porosity proper for culturing cells inside thereof as well, a method for producing the scaffold for tissue engineering includes steps of dissolving a bioabsorbable polymer material with an organic solvent, drying the solution so as to produce a porous bioabsorbable polymer material having a porosity of 50 to 99%, covering the porous bioabsorbable polymer material with a bioabsorbable polymer material having a thickness of 0.01 to 5 mm, pores of 10 to 3000 μm diameter, a fracture strength of 0.05 to 0.15 MPa, and a volume of 15 to 90% with respect to the whole scaffold. | 10-01-2009 |
20090261492 | BLOCK-SHAPED SCAFFOLD FOR TISSUE ENGINEERING AND PRODUCTION METHOD THEREOF - A block-shaped scaffold for a tissue engineering with improved shape stability and less volume change in water is produce by the steps of approximate-uniformly mixing the particle-shaped material having 100 to 2000 μm diameter with a solution, where a biodegradable polymer is dissolved with an organic solvent, freezing, drying it to remove the solvent, pulverizing thus obtained intermediate product, dissolving it with a liquid, where the biodegradable polymer is not dissolved, to remove the particle-shaped material taking thus obtained intermediate product into a mold, and pressing and heating it, the scaffold having ununiform and continuous holes occupying 20 to 80% in a cross-section area in a three-dimensional network structure having a small hole structure with 5 to 50 μm diameter, elastic coefficient being 0.1 to 2.5 MPa, and volume change being 95 to 105% when dipping it in water for 24 hours. | 10-22-2009 |
20130156820 | PRODUCTION METHOD OF TISSUE REGENERATION MATERIAL AND TISSUE REGENERATION MATERIAL - Provided is a production method of a tissue regeneration material whereby a cell suspension can be seeded and cultured on a porous support having relatively large pores. The method comprises: contacting a porous body to a holding plate having a contact angle to water of 15 to 90°, the porous body being formed of a bioabsorbable polymer material, having a thickness of 2 to 100 mm, an interconnected porous structure with a pore diameter of 180 to 3500 μm and an average pore diameter of 350 to 2000 μm, a porosity of 60 to 95%, and a compressive strength of 0.05 to 1 MPa, and being filled with a cell suspension having a cell density of 5×10 | 06-20-2013 |
20130259838 | CULTURED CARTILAGE TISSUE MATERIAL - Provided is a cultured cartilage tissue material which enables formation of cartilage tissue being substantially the same as the cartilage tissue actually in the living body, and which is large in volume. The cultured cartilage tissue material is to be used for cartilage regeneration and comprises chondrocytes, and is a mixed body of chondrocytes in a concentration of 1×10 | 10-03-2013 |
20140371748 | FRACTURE TREATMENT DEVICE - Provided is a fracture treatment device enabling efficient bone regeneration. The fracture treatment device ( | 12-18-2014 |
20150142128 | TISSUE REGENERATION CONSTRUCT AND METHOD FOR PRODUCING TISSUE REGENERATION CONSTRUCT - Provided is a tissue regeneration construct having a good engraftment property and capable of promoting a stable and favorable regeneration to a target site, the tissue regeneration construct being a member to be applied to a target site for transplantation and regeneration to regenerate tissue, including a transplant body, and an engraftment layer arranged overlapping at least a part of an outer surface of the transplant body, wherein: the transplant body includes a support, cells for regenerating the tissue that are arranged at least either one of a space between the supports and a space formed by a pore inside the support, and a base material for retaining the cells; the base material of the engraftment layer is gelatinous; and the engraftment layer is a layer in which the support does not exist. | 05-21-2015 |