Inventors list

Assignees list

Classification tree browser

Top 100 Inventors

Top 100 Assignees


Karl K.

Karl K. Berggren, Delft NL

Patent application numberDescriptionPublished
20120009390GUIDED SELF-ASSEMBLY OF BLOCK COPOLYMER LINE STRUCTURES FOR INTEGRATED CIRCUIT INTERCONNECTS - Complex self-assembled patterns can be created using a sparse template and local changes to the shape or distribution of the posts of the template to direct pattern generation of block copolymer. The post spacing in the template is formed commensurate with the equilibrium periodicity of the block copolymer, which controls the orientation of the linear features. Further, the posts can be arranged such that the template occupies only a few percent of the area of the final self-assembled patterns. Local aperiodic features can be introduced by changing the period or motif of the lattice or by adding guiding posts. According to one embodiment, an array of carefully spaced and shaped posts, prepared by electron-beam patterning of an inorganic resist, can be used to template complex patterns in a cylindrical-morphology block copolymer. These complex self-assembled patterns can form a mask used in fabrication processes of arbitrary structures such as interconnect layouts.01-12-2012

Karl K. Eilender, New York City, NY US

Patent application numberDescriptionPublished
20080306462DISPOSABLE MULTILAYERED LOW FRICTION DOUBLE LUBRICATED BED PAD - A disposable multilayered double lubricated bed pad is disclosed. Specifically, a lubricated pad for preventing and treating bedsores on a person's body and for managing discharged body fluids is disclosed. Among other things, the disclosed pad has absorbing layers and means for managing discharged body fluids away from a person's body to the absorbing layers. The disclosed pad also has a lubricating layer and is constructed to minimize friction between a person's body and a supporting surface. The disclosed pad is also treated with a lubricating, skin protecting, and moisturizing emollient for the treatment and prevention of pressure sores The emollient can be microencapsulated in the lubricating layer.12-11-2008
20080306464DISPOSABLE MULTILAYERED LOW FRICTION DOUBLE LUBRICATED ADULT BRIEF - A disposable multilayered adult brief is disclosed. Specifically, a lubricated adult brief pad for preventing and treating bedsores on a person's body and for managing discharged body fluids is disclosed. Among other things, the disclosed adult brief has a contoured lubricated pad panel and a perimeter panel. The contoured lubricated pad panel has absorbing layers and means for managing discharged body fluids away from a person's body to the absorbing layers. The adult brief also has a lubricating layer and is constructed to minimize friction between a person's body and a supporting surface. The adult brief is also treated with a lubricating, skin protecting, and moisturizing emollient for the treatment and prevention of pressure sores. The emollient can be microencapsulated in the lubricating layer.12-11-2008
20090044815FOOT AND HEEL SKIN SHIELD SYSTEM - A foot and heel skin shield system for preventing and treating pressure sores on a person's foot and calf and for managing discharged body fluids from the person's foot and calf is disclosed. The system has two main components, a heel lift and a lubricated disposable calf liner pad. An optional foot stabilizer pad may also be used as part of the system. The system may also include a heel bootie. The lubricated disposable calf liner pad, foot stabilizer pad, and heel boot can have a first lubricant having silicone and a second lubricant having a lubricating, skin protecting, and moisturizing emollient applied to the first lubricant.02-19-2009

Karl K. Johe, Potomac, MD US

Patent application numberDescriptionPublished
20090263901STABLE NEURAL STEM CELL LINES - A systematic and efficient method for establishing stable neural stem cell lines and neuronal progenitor lines is described. The resulting cell lines provide robust, simple, and reproducible cultures of human and other mammalian neurons in commercially useful mass quantities while maintaining normal karyotypes and normal neuronal phenotypes.10-22-2009
20090297486Survival, Differentiation and Structural Integration Of Human Neural Stem Cells Grafted Into the Adult Rat Spinal Cord - The present invention provides methods and compositions for treating spinal cord diseases and injuries. The methods involve transplanting neural stem cells which have been previously expanded in vitro into a patient such that the cells can ameliorate the disease or injury. The stem cells to be transplanted are derived from spinal cord tissue.12-03-2009
20100034784USE OF FUSED NICOTINAMIDES TO PROMOTE NEUROGENESIS - The present invention provides a group of compounds found to increase the number of neurons derived from stem cells for use as a therapeutic agent in neurological conditions or diseases. In one embodiment of the present invention, the compounds are used to detect the mechanism by which the number of neurons is increased.02-11-2010
20100055075METHODS OF TREATING ISCHEMIC SPASTITICY - The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.03-04-2010
20100239541TRANSPLANTATION OF HUMAN NEURAL CELLS FOR TREATMENT OF NEURODEGENERATIVE CONDITIONS - A method of treating neurodegenerative conditions is provided. Neural stem cells may be implanted at and/or remote from a region of neuron degeneration. The methods can include isolating neural stem cells from regions where specific types of neurons corresponding to the neurons to be replaced are generated. The methods can include isolating neural stem cells secreting growth factors affecting the growth and/or regeneration of specific types of neuron. In this invention, we disclose a method of treating such disorders, including several neurodegenerative disorders arising from the lack of cells that produce particular neurotransmitters in neural circuitry by transplanting exogenously cultured and expanded neural progenitors which, upon transplantation into a neural tissue, differentiate into neurons capable of integrating and producing neurotransmitters in sufficient quantities and in a sufficient manner to overcome the symptoms associated with the neurodegeneration.09-23-2010
20110052552COMPOSITIONS TO EFFECT NEURONAL GROWTH - Compositions containing neurogenic agents for inhibition of neuron death and inducing proliferation of neural cells are disclosed03-03-2011
20110135612COMPOSITIONS TO EFFECT NEURONAL GROWTH - Compositions containing neurogenic agents for inhibition of neuron death and inducing proliferation of neural cells are disclosed.06-09-2011
20120027733COMPOSITIONS TO EFFECT NEURONAL GROWTH - Compositions containing neurogenic agents for inhibition of neuron death and inducing proliferation of neural cells are disclosed.02-02-2012

Patent applications by Karl K. Johe, Potomac, MD US

Karl K. Jonietz, Santa Fe, NM US

Patent application numberDescriptionPublished
20090131617Coating for leak detection and method - A coating is used to detect a fluid leak.05-21-2009
20110165684COATING FOR LEAK DETECTION AND METHOD - A coating is used to detect a fluid leak.07-07-2011

Karl K. Moody, Iii, Essex Junction, VT US

Patent application numberDescriptionPublished
20110077882SYSTEM AND METHOD FOR ESTIMATING LEAKAGE CURRENT OF AN ELECTRONIC CIRCUIT - Disclosed are embodiments of a system and of an associated method for estimating the leakage current of an electronic circuit. The embodiments analyze a layout of an electronic circuit in order to identify all driven and non-driven nets within the electronic circuit, to identify all of the driven net-bounded partitions within the electronic circuit (based on the driven and non-driven nets), and to identify, for each driven net-bounded partition, all possible states of the electronic circuit that can leak. Then, using this information, the embodiments estimate the leakage current of the electronic circuit. This is accomplished by first determining, for each state of each driven net-bounded partition, a leakage current of the driven net-bounded partition and a probability that the state will occur in the driven net-bounded partition during operation of the electronic circuit. Then, for each state of each driven net-bounded partition, the leakage current of the driven net-bounded partition and the state probability are multiplied together. The results are then aggregated.03-31-2011

Karl K. Ng, Warwick, RI US

Patent application numberDescriptionPublished
20110097315Enantiomers of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-[3-(3-- hydroxy-3-methyl-but-1-ynyl)-phenyl]-1-methyl-1H-quinolin-2-one and salts thereof, useful in the treatment of cancer - This invention relates to the enantiomers of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-43-[3-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-1-methyl-1H-quinolin-2-one, prodrugs thereof, and pharmaceutically acceptable salts and solvates of said compounds and said prodrugs, that are useful in the treatment of hyperproliferative diseases, such as cancers, in mammals. The invention also relates to processes for the production of enantiomerically pure or optically enriched (+)- or (−)-6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-[3-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-1-methyl-1H-quinolin-2-one enantiomers from a mixture containing two enantiomers using continuous chromatography. The invention further relates to the L-(+)-tartaric acid or (S)-(−)-1,1′-binapthyl-2,2′-diyl hydrogenphosphate salts of (+)-6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-[3-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-1-methyl-1H-quinolin-2-one.04-28-2011

Karl K. Stensvad, Grove Heights, MN US

Patent application numberDescriptionPublished
20110067234METHOD FOR CONTINUOUS SINTERING ON INDEFINITE LENGTH WEBS - A method of applying a conductive pattern of metal onto a web of indefinite length material. This method includes applying a metal containing composition onto the web in a predefined pattern, providing a roll having a very low thermal mass, and conveying the patterned web around the roll while simultaneously applying heat energy to the metal containing composition thereby converting the metal to a conductive pattern. This allows for flexible circuitry to be fabricated in an inexpensive roll-to-roll process.03-24-2011

Karl K. Stensvad, Inver Grove Heights, MN US

Patent application numberDescriptionPublished
20120081908LIGHT DIRECTING EXPANDABLE ENVELOPE - Disclosed is an expandable envelope that comprises a light directing film this both transmits and reflects light. In its inflated form and along with a light source, the envelope forms a light balloon that due to the light directing film provides directed light to an area surrounding the balloon.04-05-2012