Karczewski
Aleksander Edward Karczewski, Berkeley, CA US
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20100087318 | Herbicidal Compositions - The present invention provides an improved herbicidal composition including (a) an effective amount of an herbicidal cyclohexandione oxime compound or agriculturally acceptable salt thereof; (b) one or more esters of a fatty acid; (c) a salt of dodecylbenzensulfonic acid; (d) at least one nonionic surfactant selected from the group consisting of polyoxyethylene plant oils and polyoxyethylene sorbitan esters; and (e) optionally another herbicide. | 04-08-2010 |
James Karczewski, Grand Rapids, MI US
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20120023862 | INTERNAL POST AND BEAM CONNECTION ASSEMBLY - The present invention relates to a concealed, centerline load-bearing and adjustable connector which binds a plurality of structural members together on one or more axes to create a joint which is sturdy for construction applications and the like. The present invention is configured to withstand the variables associated with timber materials, and other like structural members, such as shrinkage and timber twisting, which can occur after the joint is in place. In this way, the present invention provides a concealed, centerline load-bearing and adjustable connector that is easier to install, can be assembled on or offsite, provides a secure joint which is as good or better than the mortise-and-tenon joints of the past, and is adjustable once in place. | 02-02-2012 |
Konrad Karczewski, Stanford, CA US
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20130116930 | Method and System for Assessment of Regulatory Variants in a Genome - The present invention provides methods embodied in a system that can be applied to genetic information comprising an individual genome to assess the regulatory impact of specific genetic variants and their possible impact on biological function or disease pathology. | 05-09-2013 |
20130116931 | Method and System for the Use of Biomarkers for Regulatory Dysfunction in Disease - Measuring of the binding of a transcription factor (using, for example, chromatin immunoprecipitation) according to the present invention is provides an improved marker for a disease. These markers can be used in diagnostics for diseases where a transcription factor binding event plays a role. Additionally, they can be used to adjust disease risk profiles for healthy individuals as with typical genetic variants. | 05-09-2013 |
Konrad J. Karczewski, Stanford, CA US
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20130085728 | Method And System For Phasing Individual Genomes In The Context Of Clinical Interpretation - The present disclosure presents a unified system to phase a personal genome for downstream clinical interpretation. In an embodiment, an initial phasing is generated using public datasets, such as haplotypes from the 1000 Genomes Project, and a phasing toolkit. A local perturbation algorithm is applied to improve long range phasing. If available, a Mendelian inheritance pipeline is applied to identify phasing of novel and rare variants. These datasets are merged, followed by correction by any experimental data. This allows for full clinical interpretation of the role of a group of variants in a gene, whether inherited or de novo variants. | 04-04-2013 |
Michael Karczewski, Plainfield, IL US
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20100306041 | METHOD AND SYSTEM FOR DISTRIBUTING LEAD GENERATION FEES - A system for distributing a loan lead generation fee, including: a computer including a processor in communication with a computer-readable medium and a network, the computer-readable medium having a database stored thereon, the database including a listing of the plurality of participants and hierarchical relationships therebetween; a participant input subsystem operably connected to the computer and to the network; a lead generation fee payment subsystem for receiving the lead generation fee that is generated upon closing of the loan; a calculation subsystem for calculating loan lead generation fee payments to be made to at least one participant, wherein the calculation subsystem calculates a fraction of the loan lead generation fee payment to pay the at least one participant based on the hierarchical relationship between the at least one participant and the plurality of participants; and a payment subsystem for distributing a payment to the at least one participant. | 12-02-2010 |
Peter Karczewski, Berlin DE
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20140199318 | AGONISTIC AUTOANTIBODIES TO THE ALPHA1-ADRENERGIC RECEPTOR AND THE BETA2-ADRENERGIC RECEPTOR IN ALZHEIMER'S AND VASCULAR DEMENTIA - The invention relates to means for detecting, binding, removing and/or neutralising agonistic antibodies associated with dementia, preferably Alzheimer's disease or vascular dementia. | 07-17-2014 |