Patent application number | Description | Published |
20090087362 | Cathode Active Material Coated With Fluorine Compound for Lithium Secondary Batteries and Method for Preparing the Same - Disclosed herein is a cathode active material coated with a fluorine compound for lithium secondary batteries. The cathode active material is structurally stable, and improves the charge-discharge characteristics, cycle characteristics, high-voltage characteristics, high-rate characteristics and thermal stability of batteries. | 04-02-2009 |
20090305973 | NOVEL PEPTIDE AND USE THEREOF - The present invention relates to a novel peptide and use thereof, more particularly to an isolated peptide comprising 21-41 contiguous amino acids selected from the amino acid sequence of SEQ ID NO: 1 or the amino acid sequence having at least 90% sequence homology to the amino acid sequence of SEQ ID NO: 1 and methods for promoting fibroblast proliferation and wound healing, which comprise administering to a subject in need thereof an effective amount of the peptide. | 12-10-2009 |
20100138941 | METHOD FOR SCREENING IMMUNE MODULATOR - Disclosed is a method for screening an immune modulator. More specifically, disclosed is a method of screening an immune modulator, an anticancer agent and an agent for treating autoimmune diseases, which regulate the cell surface expression level of gp96, using the binding of the region of amino acids 54-192 of AIMP1 to the region of amino acids 699-799 of AIMP1, set forth in SEQ ID NO: 18. Also disclosed is a method of diagnosing autoimmune diseases using the binding. | 06-03-2010 |
20110124582 | NOVEL POLYPEPTIDE HAVING ANTI-TUMOR ACTIVITY - The present invention relates to a novel polypeptide having anti-tumor activity through inducing apoptosis of endothelial cell and use thereof. More particularly, the present invention relates to a method for inducing apoptosis of endothelial cell, and for preventing or treating cancer, comprising administering to a subject in need thereof an effective amount of (a) an isolated polypeptide having the amino acid sequence of SEQ ID NO: 9 or the amino acid sequence having at least 90% sequence homology to the amino acid sequence of SEQ ID NO: 9; or (b) an isolated polynucleotide encoding the polypeptide of (a). | 05-26-2011 |
20110250701 | NOVEL APPLICATION OF AIMP1 POLYPEPTIDE - The present invention relates to a novel use of AIMP1 polypeptide, more particularly to a composition for diagnosis of arthritis comprising an antibody against AIMP1, a kit for diagnosis comprising the same, a method for diagnosis of arthritis comprising: acquiring a specimen from a subject; and detecting AIMP1 polypeptide included in the specimen, and an antibody against the AIMP1 polypeptide for diagnosis of arthritis. The present invention provides a composition for diagnosis of arthritis including an antibody against AIMP1 polypeptide as a novel diagnosis marker of arthritis, a kit for diagnosis including the same, a method for diagnosis of arthritis comprising: acquiring a specimen from a subject; and detecting AIMP1 polypeptide included in the specimen, and an antibody against the AIMP1 polypeptide for diagnosis of arthritis. The composition, kit for diagnosis, method for diagnosis and antibody against the AIMP1 polypeptide may be used to diagnose arthritis early since they allow easy diagnosis of arthritis using a specimen from the patient. | 10-13-2011 |
20120322802 | NOVEL 2, 4-PYRIMIDINE DERIVATIVES AND USE THEREOF - The present invention relates to novel 2,4-pyrimidine derivatives and a use thereof, and more particularly, to pyrimidine derivatives which are effective for systemic lupus erythematosus, a composition for preventing and treating systemic lupus erythematosus comprising the same as an active ingredient and a method for screening the same. The present inventors found novel materials inhibiting surface translocation of gp96 by mimicking a function of AIMP1 which is a molecular anchor for an intracellular residence of gp96, and identified in vitro and in vivo activity of the materials for preventing and treating SLE by alleviating SLE plasma in autoimmune diseases. Therefore, the present invention provides a novel method for screening a therapeutic agent for SLE, and preventing or treating SLE using the mechanism. | 12-20-2012 |
20130034775 | CARBON NEGATIVE ELECTRODE MATERIAL FOR LITHIUM SECONDARY BATTERY, PRODUCTION METHOD THEREOF AND LITHIUM SECONDARY BATTERY USING THE SAME - A carbon negative electrode material for a lithium secondary battery includes: a core carbon material; and a coated layer covering the core carbon material and comprising a carbon coating material and carbon fiber. | 02-07-2013 |
20140249045 | NOVEL USE OF LEUCYL TRNA SYNTHETASE - Provided is a method of screening for agents for preventing or treating mTORC1 mediated diseases by screening test agents to determine test agents that inhibit the binding ability of LRS to RagD, or RagD GTPases, and a method of reducing cell size as compared to the control group, including inhibiting the expression of intracellular LRS in the cells. | 09-04-2014 |