Patent application number | Description | Published |
20110153948 | SYSTEMS, METHODS, AND APPARATUS FOR MONITORING SYNCHRONIZATION IN A DISTRIBUTED CACHE - Systems, apparatus, and method of monitoring synchronization in a distributed cache are described. In an exemplary embodiment, a first and second processing core process a first and second thread respectively. A first and second distributed cache slices store data for either or both of the first and second processing cores. A first and second core interface co-located with the first and second processing cores respectively maintain a finite state machine (FSM) to be executed in response to receiving a request from a thread of its co-located processing core to monitor a cache line in the distributed cache. | 06-23-2011 |
20110161585 | PROCESSING NON-OWNERSHIP LOAD REQUESTS HITTING MODIFIED LINE IN CACHE OF A DIFFERENT PROCESSOR - Methods and apparatus to efficiently process non-ownership load requests hitting modified line (M-line) in cache of a different processor are described. In one embodiment, a first agent changes the state of a first data and forwards it to a second, requesting agent who stores the first data in an alternative modified state. Other embodiments are also described. | 06-30-2011 |
20110161601 | INTER-QUEUE ANTI-STARVATION MECHANISM WITH DYNAMIC DEADLOCK AVOIDANCE IN A RETRY BASED PIPELINE - Methods and apparatus relating to an inter-queue anti-starvation mechanism with dynamic deadlock avoidance in a retry based pipeline are described. In one embodiment, logic may arbitrate between two queues based on various rules. The queues may store data including local or remote requests, data responses, non-data responses, external interrupts, etc. Other embodiments are also disclosed. | 06-30-2011 |
20110161705 | MULTIPLE-QUEUE MULTIPLE-RESOURCE ENTRY SLEEP AND WAKEUP FOR POWER SAVINGS AND BANDWIDTH CONSERVATION IN A RETRY BASED PIPELINE - Methods and apparatus relating to multiple-queue multiple-resource entry sleep and wakeup for power savings and bandwidth conservation in a retry based pipeline are described. In one embodiment, a bit indicates whether a corresponding queue entry is asleep or awake with respect to arbitration for resources in a retry based pipeline. Furthermore, multiple entries from different queues may be grouped together and multiple resources may be grouped together. Other embodiments are also disclosed. | 06-30-2011 |
20110191542 | SYSTEM-WIDE QUIESCENCE AND PER-THREAD TRANSACTION FENCE IN A DISTRIBUTED CACHING AGENT - Methods and apparatus relating to system-wide quiescence and per-thread transaction fence in a distributed caching agent are described. Some embodiments utilize messages, counters, and/or state machines that support system-wide quiescence and per-thread transaction fence flows. Other embodiments are also disclosed. | 08-04-2011 |
20120079032 | APPARATUS, SYSTEM, AND METHODS FOR FACILITATING ONE-WAY ORDERING OF MESSAGES - Methods, apparatus and systems for facilitating one-way ordering of otherwise independent message classes. A one-way message ordering mechanism facilitates one-way ordering of messages of different message classes sent between interconnects employing independent pathways for the message classes. In one aspect, messages of a second message class may not pass messages of a first message class. Moreover, when messages of the first and second classes are received in sequence, the ordering mechanism ensures that messages of the first class are forwarded to, and received at, a next hop prior to forwarding messages of the second class. | 03-29-2012 |
20140115197 | INTER-QUEUE ANTI-STARVATION MECHANISM WITH DYNAMIC DEADLOCK AVOIDANCE IN A RETRY BASED PIPELINE - Methods and apparatus relating to an inter-queue anti-starvation mechanism with dynamic deadlock avoidance in a retry based pipeline are described. In one embodiment, logic may arbitrate between two queues based on various rules. The queues may store data including local or remote requests, data responses, non-data responses, external interrupts, etc. Other embodiments are also disclosed. | 04-24-2014 |
20140214955 | APPARATUS, SYSTEM, AND METHODS FOR FACILITATINGONE-WAY ORDERING OF MESSAGES - Methods, apparatus and systems for facilitating one-way ordering of otherwise independent message classes. A one-way message ordering mechanism facilitates one-way ordering of messages of different message classes sent between interconnects employing independent pathways for the message classes. In one aspect, messages of a second message class may not pass messages of a first message class. Moreover, when messages of the first and second classes are received in sequence, the ordering mechanism ensures that messages of the first class are forwarded to, and received at, a next hop prior to forwarding messages of the second class. | 07-31-2014 |
20140297967 | INTER-QUEUE ANTI-STARVATION MECHANISM WITH DYNAMIC DEADLOCK AVOIDANCE IN A RETRY BASED PIPELINE - Methods and apparatus relating to an inter-queue anti-starvation mechanism with dynamic deadlock avoidance in a retry based pipeline are described. In one embodiment, logic may arbitrate between two queues based on various rules. The queues may store data including local or remote requests, data responses, non-data responses, external interrupts, etc. Other embodiments are also disclosed. | 10-02-2014 |
20150160720 | MULTIPLE-QUEUE MULTIPLE-RESOURCE ENTRY SLEEP AND WAKEUP FOR POWER SAVINGS AND BANDWIDTH CONSERVATION IN A RETRY BASED PIPELINE - Methods and apparatus relating to multiple-queue multiple-resource entry sleep and wakeup for power savings and bandwidth conservation in a retry based pipeline are described. In one embodiment, a bit indicates whether a corresponding queue entry is asleep or awake with respect to arbitration for resources in a retry based pipeline. Furthermore, multiple entries from different queues may be grouped together and multiple resources may be grouped together. Other embodiments are also disclosed. | 06-11-2015 |
Patent application number | Description | Published |
20090184025 | MICROWAVEABLE NESTED TRAYS - One embodiment includes a package system containing a main container with a smaller container nested in it. The smaller container is filled with a secondary food item designed to be mixed into the primary food item. The smaller container is placed within the main container. The area of the main container not occupied by the smaller container includes a main food item. Both containers are sealed with one film. Before consumption, a consumer will place the package in a microwave to heat. Once heated, the smaller container is removed from the main container, creating space in the main container previously occupied by the smaller container. The main food item in the main container will re-position creating space between the top of the main food item to the edge of the main container. The secondary item can be added into the main container without overflowing out of the main container. | 07-23-2009 |
20090186131 | READY-TO-EAT FOOD TRAY AND METHOD FOR PREPARING THE SAME - A sterilised ready-meal food package comprising: a main container, defining a main volume and having a first opening at the upper part; a main food product held inside at least part of such main volume; at least one secondary container defining a secondary volume and having a second opening at the upper part; at least one secondary food product held inside at least part of the secondary volume; removable covering means arranged to occlude the first and the second opening. The main and secondary food products occupy at least 80% of the free volume available therefor; furthermore, the secondary container is associated in a removable manner inside the main container, in such a manner to occupy part of the main volume and reduce the free volume available for the main food product to a portion of the main volume. The finding also comprises a method for preparing the ready-meal food package. | 07-23-2009 |
20100282636 | MICROWAVEABLE NESTED TRAYS - One embodiment includes a package system containing a main container with a smaller container nested in it. The smaller container is filled with a secondary food item designed to be mixed into the primary food item. The smaller container is placed within the main container. The area of the main container not occupied by the smaller container includes a main food item. Both containers are sealed with one film. Before consumption, a consumer will place the package in a microwave to heat. Once heated, the smaller container is removed from the main container, creating space in the main container previously occupied by the smaller container. The main food item in the main container will re-position creating space between the top of the main food item to the edge of the main container. The secondary item can be added into the main container without overflowing out of the main container. | 11-11-2010 |
20120159715 | MATTRESSES WITH EXTENDED LENGTH HANDLES - A mattress having a top surface, a bottom surface which is opposite of and parallel to the top surface, and a right side wall, a left side wall, a first end wall and a second end wall, the right, left, bottom and top side walls being perpendicular to and extending between the top and bottom surface of the mattress. A single extended length mattress handle is attached horizontally along a substantial length of each opposing side wall of the mattress. The extended length mattress handles are sewn onto the mattress at two or more connection points and preferably at three or more points or areas on each mattress side wall. In one embodiment, the length of the mattress handles is less than the length of the side wall to which it is attached. In a second embodiment, the length of the mattress handles is greater than the length of the mattress and the handle wraps around each corner and extends onto the adjacent end wall or walls. The extended length and horizontal arrangement of the handles facilitates easier gripping and handling of the mattress. | 06-28-2012 |
Patent application number | Description | Published |
20140103040 | BEVERAGE DELIVERY CAN - A beverage delivery can may comprise various configurations. Such configurations may comprise various aperture shapes, sizes, and configurations and various shapes, textures, configurations, and dimensions of the lid and surface of the can. A beverage can may comprise various exterior shapes such as a tapered shape, a faceted shape, a pint glass shape and the like. In embodiments, the beverage can may comprise various types of nucleation devices. A beverage can may comprise a vertical portion of the can, a continuous lip indentation comprising an upper lip, a waist pinch, and a shoulder and the like. In embodiments, various external packaging may be used with one or more beverage delivery cans. | 04-17-2014 |
20140190971 | BEVERAGE DELIVERY CAN - A beverage delivery can may comprise various configurations, including various aperture shapes, sizes, and configurations and various shapes, textures, configurations, and dimensions of the lid and surface of the can. A beverage can may comprise various exterior shapes such as a tapered shape, a faceted shape, a pint glass shape and the like. In embodiments, the beverage may comprise various types of nucleation devices. A beverage can may comprise a vertical portion of the can, a continuous lip indentation comprising an upper lip, a waist pinch, and a shoulder and the like. In embodiments, various external packaging may be used with one or more beverage delivery cans. | 07-10-2014 |
20150140520 | COLOR DISPLAY SYSTEM - Color display systems are disclosed, wherein the color display system includes a main display unit and a secondary display unit. The main display unit can include a plurality of rotatable color selection pods where one side of the color selection pod displays a color(s) and the other side of the color selection pod includes receptacles that can hold color chips. The color selection pods are arranged in columns, and each column can represent a particular color family or color category. The secondary display unit can include a first sub-display and a second sub-display, with each sub-display displaying colors of particular categories or themes. The color display system can also include a central work center which can include a work table and rotating color display. | 05-21-2015 |
Patent application number | Description | Published |
20100210623 | THERAPEUTIC COMPOUNDS - The present invention relates to pyrazine substituted pyrrolopyridines which are inhibitors of JAK kinases (JAK1, JAK2, JAK3 and/or TYK2) and/or PDK1 and are thus useful for the treatment of myeloproliferative disorders or cancer. | 08-19-2010 |
20110207711 | Therapeutic Compounds - The present invention relates to pyrazolopyridines and imidazopyridines which are inhibitors of the kinase PDK1 and are thus useful for the treatment of myeloproliferative disorders or cancer. The compounds are also useful as inhibitors of other kinases such as FGFR3, NTRK3, RP-S6K and WEE1. Furthermore, the present compounds also selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease. | 08-25-2011 |
20120225886 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS - The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor. | 09-06-2012 |
20130040933 | AZAINDOLES AS JANUS KINASE INHIBITORS - The present invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof. Compounds of formula I are inhibitors of Janus kinases and as such are useful for the treatment of various diseases and conditions mediated by said enzymes, such as rheumatoid arthritis, asthma, COPD, ALS, and the like. | 02-14-2013 |
20140243309 | CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS - The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer. | 08-28-2014 |
20140303142 | AZAINDOLES AS JANUS KINASE INHIBITORS - The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer. | 10-09-2014 |
Patent application number | Description | Published |
20110196145 | PROCESS FOR DESILYLATION OF OLIGONUCLEOTIDES - The present invention relates to processes and reagents for oligonucleotide synthesis and purification. One aspect of the present invention relates to compounds useful for activating phosphoramidites in oligonucleotide synthesis. Another aspect of the present invention relates to a method of preparing oligonucleotides via the phosphoramidite method using an activator of the invention. Another aspect of the present invention relates to sulfur-transfer agents. In a preferred embodiment, the sulfur-transfer agent is a 3-amino-1,2,4-dithiazolidine-5-one. Another aspect of the present invention relates to a method of preparing a phosphorothioate by treating a phosphite with a sulfur-transfer reagent of the invention. In a preferred embodiment, the sulfur-transfer agent is a 3-amino-1,2,4-dithiazolidine-5-one. Another aspect of the present invention relates to compounds that scavenge acrylonitrile produced during the deprotection of phosphate groups bearing ethylnitrile protecting groups. In a preferred embodiment, the acrylonitrile scavenger is a polymer-bound thiol. Another aspect of the present invention relates to agents used to oxidize a phosphite to a phosphate. In a preferred embodiment, the oxidizing agent is sodium chlorite, chloroamine, or pyridine-N-oxide. Another aspect of the present invention relates to methods of purifying an oligonucleotide by annealing a first single-stranded oligonucleotide and second single-stranded oligonucleotide to form a double-stranded oligonucleotide; and subjecting the double-stranded oligonucleotide to chromatographic purification. In a preferred embodiment, the chromatographic purification is high-performance liquid chromatography. | 08-11-2011 |
20120128760 | LIPID COMPOSITIONS - Disclosed herein are lipid compositions comprising a cationic lipid of formula (I), a neutral lipid, a sterol and a PEG or PEG-modified lipid, wherein formula (I) is (F). Also disclosed are methods of producing the cationic lipid of formula (I). | 05-24-2012 |
20130053334 | MONOMERS AND OLIGONUCLEOTIDES COMPRISING CYCLOADDITION ADDUCT(S) - The invention features compounds of formula (V) or(XII). In one embodiment, the invention relates compounds and processes for conjugating ligand to oligonucleotide. The invention further relates to methods for treating various disorders and diseases such as viral infections, bacterial infections, parasitic infections, cancers, allergies, autoimmune diseases, immunodeficiencies and immunosuppression. | 02-28-2013 |
20130323269 | METHODS AND COMPOSITIONS FOR DELIVERY OF ACTIVE AGENTS - A lipid particle can include a cationic lipid. The cationic lipid can include one or more hydrophobic tails, which can include one or more sites of unsaturation. The sites of unsaturation can include cycloalkyl groups, e.g., cyclopropyl, cyclobutyl, cyclopentyl, or cyclohexyl groups. The lipid particle is suitable for delivering an active agent. | 12-05-2013 |
20150190515 | LIPID COMPOSITIONS - Disclosed herein are lipid compositions comprising a cationic lipid of formula (I), a neutral lipid, a sterol and a PEG or PEG-modified lipid, wherein formula (I) is | 07-09-2015 |
Patent application number | Description | Published |
20130068043 | APPARATUS AND METHODS FOR PREPARATION AND ANALYSIS OF DRIED SAMPLES OF A BIOLOGICAL FLUID - Described is a device for collecting a fluid sample, such as a biological fluid sample. The device includes a planar collection substrate having an absorbent material. The planar collection substrate includes an impermeable region and a sample collection region. The impermeable region is impermeable to the fluid sample and is embedded in the planar collection substrate in a spatial pattern. The sample collection region is in an area excluded from the spatial pattern and has a shape and a size defined by the spatial pattern. The sample collection region is configured to receive a known volume of the fluid sample. In an alternative form, the device includes a sample collection element disposed in an impermeable planar holder and, in another alternative form, the device includes an absorbent material disposed inside an impermeable tube wall. | 03-21-2013 |
20130327129 | SPECTROSCOPIC SAMPLE INSPECTION FOR AUTOMATED CHROMATOGRAPHY - A method and a system for generating an extraction sample from a dried sample spot. The method includes acquiring a spectroscopic image of an analyte in the spot. The spectroscopic image includes information on a spatial distribution of the analyte. A region of the spot to be extracted is determined from the spectroscopic image and an extraction sample is generated from the determined region. In other embodiments, the method and system are based on acquiring a spectroscopic measurement of an analyte in the dried sample spot, determining a quantity of the analyte in the spot based on the spectroscopic measurement and determining a volume of an extraction solvent for creating an extraction sample from the spot. The determined volume is based on the determined quantity of the analyte and a detection characteristic of an analytical measurement system. In other embodiments, the method is applied to solid samples. | 12-12-2013 |
20140208836 | ANALYSIS OF DRIED BLOOD SPOT SAMPLES IN A MICROFLUIDIC SYSTEM WITH DILUTION OF EXTRACTED SAMPLES - An apparatus for use in a chromatography system includes a microfluidic substrate having a fluidic channel configured as an analytical chromatographic column and a fluidic port on one side of the microfluidic substrate. The fluidic port opens at a head end of the analytical chromatographic column. A dried blood spot (DBS) collection device holds one or more dried biological samples. The DBS collection device is directly coupled to the microfluidic substrate whereby one of the biological samples is placed into fluidic communication with the fluidic channel of the microfluidic substrate and an extraction of that biological sample flows toward the head end of the analytical chromatographic column. A diluent source fluidically coupled to the fluidic port supplies a solvent to the head end of the analytical column to dilute the extracted biological sample before the biological sample flows into the analytical chromatographic column. | 07-31-2014 |
20140220278 | Porous Material And Devices For Performing Separations, Filtrations, And Catalysis And EK Pumps, And Mthods Of Making And Using The Same - Embodiments of the present invention are directed to a porous monolith polymeric composition having utility in catalysis, chromatography, filtration, and electro-kinetic pumps, devices incorporating such composition and methods or making and using such monoliths. The monoliths are characterized by a substantially homogeneous skeletal core with little shrinkage, few voids and few channels. | 08-07-2014 |
20140366656 | SOLID PHASE EXTRACTION DEVICE FOR DRIED SAMPLE CARDS - Described is a device for solid phase extraction of a dried sample of a biological fluid. The device includes a support structure such as a plate or support block that has a first side to receive a dried sample card. The support structure also has a second side that is opposite the first side and a number of apertures that extend between the first and second sides. The device also includes a plurality of wells each containing a sample preparation material and having an inlet end that communicates with a respective aperture at the second side of the support structure. Each dried sample on the dried sample card is aligned with one of the apertures. Extraction samples in each well pass through the sample preparation material, such as a chromatographic sorbent, in the well to remove one or more constituents of the extraction sample. | 12-18-2014 |
20140373644 | DRIED SAMPLE CARRIER HAVING DISSOLVABLE SAMPLE REGIONS - Described are sample carriers and methods of extracting a fluid sample from a dried sample on a sample carrier. The sample carrier has a first carrier portion that receives a fluid sample, and includes a material that adsorbs the fluid sample and dissolves upon application of a solvent. A second carrier portion is attached to the first carrier portion and includes a material that is indissolvable in the solvent. The first carrier portion having a dried sample is dissolved into a solution upon application of the solvent. The solution can be analyzed to determine constituents in the extracted sample. The sample carrier can conveniently be in the form of a card or a dipstick. In alternative embodiments, a carrier portion that includes the dried sample is indissolvable in the solvent but is released from another carrier portion through application of a solvent to an intervening dissolvable carrier portion. | 12-25-2014 |
20150047441 | SAMPLE CARRIER FOR DRIED BIOLOGICAL SAMPLES - Described is a biological sample carrier based on a rigid hydrophilic object fabricated from a non-absorbing inert porous material. A biological fluid sample applied to the surface of the object is absorbed into the pores and constituents of the biological fluid sample remain in the pores after drying. Unlike a disc punched from a conventional dried blood spot (DBS) card, the object is easily handled. In contrast to DBS cards containing glass fiber structures that interact with basic analytes and other DBS card having adsorbing fibers that tend to separate blood constituents as the sample spreads through the fibers, the biological sample carrier is substantially inert to drug analytes. | 02-19-2015 |
Patent application number | Description | Published |
20090100536 | Transgenic plants with enhanced agronomic traits - This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits. | 04-16-2009 |
20100074907 | Methods for Promoting Myelination, Neuronal Survival and Oligodendrocyte Differentiation Via Administration of SP35 or TrkA Antagonists - This invention relates to methods for promoting myelination, neuronal survival, and oligodendrocyte differentiation and treating demyelination and dysmyelination disease by the administration of a TrkA antagonist. The invention also relates to methods of inhibiting or decreasing Sp35 expression by the use of a TrkA antagonist. Additionally, the invention relates generally to methods for blocking Sp35 and TrkA interaction and inhibiting or decreasing TrkA phosphorylation by the administration of a Sp35 antagonist. | 03-25-2010 |
20110258734 | GENE SEQUENCES AND USES THEREOF IN PLANTS - This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits. | 10-20-2011 |
20130074202 | GENE SEQUENCES AND USES THEREOF IN PLANTS - This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits. | 03-21-2013 |
Patent application number | Description | Published |
20080311402 | ORIENTATION-CONTROLLED SELF-ASSEMBLED NANOLITHOGRAPHY USING A BLOCK COPOLYMER - Disclosed is a structure made of a trench patterned substrate having a pre-determined trench period and a pre-determined mesa to trench width ratio, and a block copolymer on top of the trench patterned substrate. The block copolymer has at least an organic block and a silicon-containing block, wherein the block copolymer can have either perpendicular or parallel cylinders. The structure is annealed under a pre-determined vapor pressure for a predetermined annealing time period, wherein the pre-determined trench period, the pre-determined mesa to trench width ratio, the predetermined vapor pressure and the predetermined annealing time period are chosen such that cylinders formed in the block copolymer are either perpendicular or parallel with respect to the trench-patterned substrate. A method is also described to form the above-mentioned structure. | 12-18-2008 |
20090092803 | SELF-ASSEMBLY TECHNIQUE APPLICABLE TO LARGE AREAS AND NANOFABRICATION - The present invention provides articles and methods for affecting the self-assembly of materials. In some cases, the invention provides an approach for facilitating the self-assembly of various materials, including polymeric materials (e.g., block polymers), nanoparticles, other materials capable of self-assembly, and the like, over relatively large surface areas. Some embodiments of the invention provide articles (e.g., substrates) which, when contacted with a material capable of self-assembly, may produce greater control of self-assembly through the bulk of the material. | 04-09-2009 |
20120009390 | GUIDED SELF-ASSEMBLY OF BLOCK COPOLYMER LINE STRUCTURES FOR INTEGRATED CIRCUIT INTERCONNECTS - Complex self-assembled patterns can be created using a sparse template and local changes to the shape or distribution of the posts of the template to direct pattern generation of block copolymer. The post spacing in the template is formed commensurate with the equilibrium periodicity of the block copolymer, which controls the orientation of the linear features. Further, the posts can be arranged such that the template occupies only a few percent of the area of the final self-assembled patterns. Local aperiodic features can be introduced by changing the period or motif of the lattice or by adding guiding posts. According to one embodiment, an array of carefully spaced and shaped posts, prepared by electron-beam patterning of an inorganic resist, can be used to template complex patterns in a cylindrical-morphology block copolymer. These complex self-assembled patterns can form a mask used in fabrication processes of arbitrary structures such as interconnect layouts. | 01-12-2012 |
Patent application number | Description | Published |
20100298568 | Processes and intermediates for preparing steric compounds - This invention relates to processes and intermediates for the preparation of an alpha-amino beta-hydroxy acid of Formula 1 | 11-25-2010 |
20110071074 | DEUTERATED HEPATITIS C PROTEASE INHIBITORS - A deuterated α-ketoamido steric specific compound of the formula | 03-24-2011 |
20130102782 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES - The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK). | 04-25-2013 |
20130131359 | PROCESSES AND INTERMEDIATES FOR PREPARING STERIC COMPOUNDS - This invention relates to processes and intermediates for the preparation of an alpha-amino beta-hydroxy acid of Formula 1 | 05-23-2013 |
20130253181 | METHODS OF PREPARING SUBSTITUTED NUCLEOTIDE ANALOGS - Disclosed herein are methods of preparing a phosphorothioate nucleotide analog, which are useful in treating diseases and/or conditions such as viral infections. | 09-26-2013 |
20130266538 | Solid Forms of a Thiophosphoramidate Nucleotide Prodrug - The present application relates to solid state forms, for example, crystalline forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, pharmaceutical compositions that can include one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, and methods of treating or ameliorating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate. Also disclosed herein are methods of treating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate in combination with one or more other agents. | 10-10-2013 |
20130281687 | METHODS OF PREPARING SUBSTITUTED NUCLEOTIDE ANALOGS - Disclosed herein are methods of preparing a phosphorothioate nucleotide analog, which are useful in treating diseases and/or conditions such as viral infections. | 10-24-2013 |
20130303764 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES - The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK). | 11-14-2013 |
20130324743 | PROCESS OF PRODUCING CYCLOALKYLCARBOXAMIDO-INDOLE COMPOUNDS - The present invention features processes for preparing compounds, such as (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1), useful for treating CFTR mediated diseases such as cystic fibrosis. | 12-05-2013 |
20140154210 | Solid Forms of a Thiophosphoramidate Nucleotide Prodrug - The present application relates to solid state forms, for example, crystalline forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, pharmaceutical compositions that can include one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, and methods of treating or ameliorating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate. Also disclosed herein are methods of treating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate in combination with one or more other agents. | 06-05-2014 |
20140309413 | METHODS OF STEREOSELECTIVE SYNTHESIS OF SUBSTITUTED NUCLEOSIDE ANALOGS - The present invention relates to the novel diastereoselective syntheses for generating phosphorothioate compounds. Examples include nucleoside phosphorothioate analogs that are useful in treating diseases and/or conditions such as viral infections. | 10-16-2014 |
20140309421 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES - The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK). | 10-16-2014 |
20150099884 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES - The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK). | 04-09-2015 |
20150175647 | SOLID FORMS OF A THIOPHOSPHORAMIDATE NUCLEOTIDE PRODRUG - The present application relates to solid state forms, for example, crystalline forms of 2′-C-methyluridine-5′-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, pharmaceutical compositions that can include one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, and methods of treating or ameliorating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate. Also disclosed herein are methods of treating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate in combination with one or more other agents. | 06-25-2015 |
20150218122 | Process of Producing Cycloalkylcarboxamido-indole Compounds - The present invention features processes for preparing compounds, such as (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1), useful for treating CFTR mediated diseases such as cystic fibrosis. | 08-06-2015 |
Patent application number | Description | Published |
20100183844 | HIGHLY ORGANIZED SINGLE-WALLED CARBON NANOTUBE NETWORKS AND METHOD OF MAKING USING TEMPLATE GUIDED FLUIDIC ASSEMBLY - Methods for fabricating templates for nanoelement assembly and methods for fluid-guided assembly of nanoelements are provided. Templates are fabricated by plasma modification of surface hydrophilicity and production of a network of hydrophobic trenches having a hydrophilic bottom surface. Single-walled carbon nanotubes (SWNT) can be assembled into stable films, ribbons, and wires of nanoscale thickness and nanoscale or microscale width and length. The nanofilm assemblies prepared according to the invention are highly conductive and can be used in the fabrication of a wide variety of microscale and nanoscale electronic devices. | 07-22-2010 |
20120027681 | Low-Aspect Ratio Carbon Nanostructures - Low-aspect ratio nanostructures, such as nanocups, nanorings, and arrays of nanocups and nanorings, methods of fabrication of nanostructures, and methods of using nanostructures are disclosed. | 02-02-2012 |
20140197046 | Chemical Sensor Based on Highly Organized Single Walled Carbon Nanotube Networks - A carbon nanotube-based micron scale chemical sensor or sensor array is provided that enables the remote detection of hydrogen sulfide and other chemicals in a gas stream. The sensor is suitable for use in harsh environments of high temperature and pressure such as those encountered during petrochemical exploration and recovery. Multiplex sensor devices detect two or more chemical agents simultaneously, or they can detect conditions such as pressure, salinity, humidity, pH, or scale-forming ions. Incorporation of read out electronics and an RF signal generator into the sensor device enables it to communicate to a relay station or receiver for 3D mapping or other analysis. Methods are also provided for fabricating the chemical sensor device and using the device for detection. | 07-17-2014 |
20150228917 | Optoelectronic Devices Based on Heterojunctions of Single-Walled Carbon Nanotubes and Silicon - Heterojunctions of single-walled carbon nanotubes and p-doped silicon produce a photocurrent when irradiated with visible light under reverse bias conditions. In optoelectronic devices utilizing the heterojunctions, the output current can be controlled completely by both optical and electrical inputs. The heterojunctions provide a platform for heterogeneous optoelectronic logic elements with high voltage-switchable photocurrent, photo-voltage responsivity, electrical ON/OFF ratio, and optical ON/OFF ratio. The devices are combined to make switches, logic elements, and imaging sensors. An assembly of 250,000 sensor elements on a centimeter-scale wafer is also provided, with each sensor element having a heterojunction of single-walled carbon nanotubes and p-doped silicon, and producing a current dependent on both the optical and the electrical input. | 08-13-2015 |