| Patent application number | Description | Published |
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| 20100261269 | Activation and Expansion of T-Cells Using An Engineered Multivalent Signaling Platform as a Research Tool - Provided are a system and methods for selectively inducing expansion of a population of T cells in the absence of exogenous growth factors, such as lymphokines, and accessory cells for research purposes. The cell based expansion system and methods permit the long-term growth of CTLs, preferably human CTLs. In addition, T cell proliferation can be induced without the need for antigen, thus providing an expanded T cell population that is polyclonal with respect to antigen reactivity. Further provided are methods for using the system and methods to screen and identify antigens related to specific diseases or conditions, tumors, autoimmune disorders, or an infectious disease or pathogen, and to identify target molecule for research purposes, or for developing a vaccine based thereon. | 10-14-2010 |
| 20110052547 | RAPAMYCIN-RESISTANT T CELLS AND THERAPEUTIC USES THEREOF - Methods for generating highly enriched Th1/Tc1 and Th2/Tc2 functions are described. In particular, the generation of these functions are attained by the addition of an immune suppression drug, rapamycin or a rapamycin derivative compound. In addition to enhanced purity of T cell function, the T cells generated in rapamycin also express molecules that improve immune T cell function such as CD28 and CD62L. Such rapamycin generated functional T cell subsets may have application in the prevention or treatment of GVHD after allogeneic hematopoietic stem cell transplantation, the treatment of autoimmunity, or the therapy of infection or cancer. | 03-03-2011 |
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| 20100101800 | Subsea Completion with a Wellhead Annulus Access Adapter - A subsea completion assembly for a subsea well including installed casing and a wellhead. The assembly includes a production casing forming a B annulus between the outside of the production casing and the installed casing. The assembly also includes an annulus access adapter installed in the wellhead, the adapter including a manipulatable valve controlling fluid communication with the fluid in the B annulus across the annulus access adapter. A property of the fluid in the B annulus can be monitored by fluid communicated across the annulus access adapter. | 04-29-2010 |
| 20100229981 | SELF-SEALING HYDRAULIC CONTROL LINE COUPLING - There is provided a hydraulic fluid control line connector including first and second couplings configured to automatically seal shut when the members are disengaged. There is further provided a method for blocking contamination or pressure transfer of hydraulic fluid control lines by securing first and second couplings to corresponding ends of a hydraulic line and automatically sealing the couplings shut when the couplings are disengaged. | 09-16-2010 |
| 20100294492 | Function Spool - A production assembly and method for controlling production from production tubing supported by a tubing hanger in a well including a wellhead. The assembly includes a function spool engaged with the wellhead and a tree engaged with the function spool. The tubing hanger is landable in the tree bore such that the production tubing is supported in the well by the tree. A function mandrel separate from the tubing hanger is engaged with the production tubing and positionable inside the function spool bore. The function mandrel includes a passage connected to a line extending into the well that is connectable with a port in the function spool such that communication with a downhole component through the line is allowable from outside the function spool. | 11-25-2010 |
| 20110017467 | Multi-Section Tree Completion System - A subsea well production system for a well including a subsea wellhead. The system includes a multi-section production tree that includes a landing section engageable with the subsea wellhead and including a landing section bore. The tree also includes a valve section separate from and engageable with the landing section, the valve section including a lateral production port extending through a valve section wall and in communication with a valve section bore. A production tubing supported by a tubing hanger is installed and supported in the landing section bore such that the tubing hanger extends into the valve section bore. The tubing hanger and production tubing are retrievable through the section bores without disengaging the valve section from the landing section. The valve section is also disengageable from the landing section with the tubing hanger remaining in the landing section. | 01-27-2011 |
| 20110108279 | SELF-SEALING CHEMICAL INJECTION LINE COUPLING - There is provided a chemical injection line connector including first and second couplings configured to automatically seal shut when the members are disengaged. There is further provided a method for blocking contamination or pressure transfer of chemical injection lines by securing first and second couplings to corresponding ends of a chemical injection line and automatically sealing the couplings shut when the couplings are disengaged. | 05-12-2011 |
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| 20090116190 | Controlling Airflow In A Computer Chassis - Computer chassis configured for controlled airflow including at least one component board; a segmented curtain suspended across a region of airflow in the computer chassis above the component board; and at least one component mounted on the component board displacing at least one segment of the segmented curtain creating an airflow channel under the displaced segment. Segmented curtains for controlling airflow in a computer chassis including one or more segments capable of being displaced by components mounted on a component board in the computer chassis; and one or more fasteners for suspending the segmented curtain across a region of airflow in the computer chassis. Controlling airflow in a computer chassis including inserting a component board into the computer chassis; displacing, a segment of a segmented curtain thereby creating an airflow channel; and providing airflow through the airflow channel created by the displacement of the segment of the segmented curtain. | 05-07-2009 |
| 20110044008 | TOP ACTUATED, FORCE LIMITING HEATSINK RETENTION SYSTEM - Apparatus for securing or retaining a heatsink. The heatsink retention apparatus includes a heatsink module that cooperates with first and second spring loaded latches secure to a circuit board on opposing sides of a heat-generating component. The heatsink module includes a handle pivotally secured to opposing sides of the heatsink body, and bails pivotally secured to the handle. In addition, the bails extend downward to dispose a lower bail member adjacent the spring loaded latches. As the handle pivots between a first position to raise the bails and a second position to lower the bails, the bails automatically move from a locked position to an unlocked position. Each of the spring loaded latches include a hook and at least one pre-loaded spring to transfer a minimum downforce to the lower bail members when the bails are raised. Accordingly, embodiments may be operated from the top of the heatsink without the use of tools, while providing a desired downforce over a range of heatsink heights. | 02-24-2011 |
| 20110250047 | Airflow From A Blower With One Or More Adjustable Guide Vanes That Are Affixed To The Blower At One Or More Pivot Points Located In An Outlet Of The Blower - Methods, apparatus, and products are disclosed for improving the airflow exiting a blower that has one or more adjustable guide vanes that are affixed to the blower at one or more pivot points located in an outlet of the blower that include: determining a rotational speed of an impeller in the blower and adjusting a position of at least one of the adjustable guide vanes in dependence upon the rotational speed of the impeller. | 10-13-2011 |
| 20110250048 | Airflow From A Blower With One Or More Adjustable Guide Vanes That Are Affixed To The Blower At One Or More Pivot Points Located In An Outlet Of The Blower - Methods, apparatus, and products are disclosed for improving the airflow exiting a blower that has one or more adjustable guide vanes that are affixed to the blower at one or more pivot points located in an outlet of the blower that include: determining a rotational speed of an impeller in the blower and adjusting a position of at least one of the adjustable guide vanes in dependence upon the rotational speed of the impeller. | 10-13-2011 |
| 20110250049 | Airflow From A Blower With One Or More Adjustable Guide Vanes That Are Affixed To The Blower At One Or More Pivot Points Located In An Outlet Of The Blower - Methods, apparatus, and products are disclosed for improving the airflow exiting a blower that has one or more adjustable guide vanes that are affixed to the blower at one or more pivot points located in an outlet of the blower that include: determining a rotational speed of an impeller in the blower and adjusting a position of at least one of the adjustable guide vanes in dependence upon the rotational speed of the impeller. | 10-13-2011 |
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| 20080304229 | AIR-PRESSURE-DEPENDENT CONTROL OF COOLING SYSTEMS USING A SHARED AIR PRESSURE SENSOR - Systems and methods provide altitude-dependent fan control for a plurality of electronic subsystems using a shared air pressure sensor. Each server or multi-server chassis of a rack system is a subsystem of the rack system. Each subsystem receives its own on-board fan or blower module. The shared air pressure sensor senses air pressure and outputs a signal to all of the subsystems. Each subsystem then independently regulates its own fan speed according to the signal output by the shared air pressure sensor. Other fan operational parameters, such as the number of fans recruited, may also be controlled according to altitude according to the invention. A variety of other performance parameters, such as internal air or component temperature, ambient air temperature, server workload, and processor activity level, may also be factored into control of these fan operational parameters. | 12-11-2008 |
| 20090207565 | Ducted Air Temperature Sensor - A temperature isolation duct in a computer system comprising a chassis securing a circuit board and a fan system, wherein the fan system draws air through the chassis in an airflow direction, and a heat-generating component is mounted on the circuit board and exposed to the air flow. The hot air duct passively directs air heated by the heat-generating component from a single hot air duct inlet in direct downstream alignment with the heat-generating component to a single hot air duct outlet, wherein the hot air duct has a length to width aspect ratio of greater than four. A first thermal sensor is secured within, or direct alignment with, the hot air duct near the duct outlet for sensing the temperature of air flowing through the hot air duct and generating a first temperature signal. A controller is in electronic communication with the first thermal sensor for receiving the temperature signal and in electronic communication with the fan system for sending a fan speed control signal. Optionally, the hot air duct may extend through, over or around a second component on the circuit board to avoid thermal effects of the second component. | 08-20-2009 |
| 20090249862 | System and Method for Determining Air Density Based on Temperature Sensor Data - A computer system and method for measuring air density in a computer chassis. The computer chassis includes a fan, an ambient air temperature sensor, and a heat-generating device with a heat sink, a heat sink temperature sensor, and a controller. The controller controls the fan speed and applies a known amount of thermal energy to the heat sink, then determines the air density from the difference in temperature between the ambient air and the heat sink. The controller may then use the air density determination to adjust the air flow rate through the computer chassis to provide a proper air flow rate for cooling. | 10-08-2009 |
| 20090257872 | Reduced-Impedance Cooling System With Variable Pitch Blade And Hot-Swappable Spare - A method of operating variable pitch fans in series to cool an operating computer system. The method comprises running a first variable pitch fan with blades positioned at an operational pitch to induce airflow through the computer system and through a second variable pitch fan disposed in series with the first fan, and, simultaneously, not running the second variable pitch fan with blades positioned for minimal impedance to the airflow. In response to detecting a failure condition of the first fan, the method includes running the second fan with blades positioned at an operational pitch to induce airflow through the computer system and through the first fan, and, simultaneously, not running the first fan with blades positioned for minimal impedance to the airflow. Preferably, the method includes locking the rotor of a fan that is not running, and locking the blades of the non-running fan in a minimal impedance position. | 10-15-2009 |
