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Jun Yuan, Guilford US

Jun Yuan, Guilford, CT US

Patent application numberDescriptionPublished
20080227793Benzimidazole and Pyridylimidazole Derivatives - This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I09-18-2008
20080267887Pyrrolo-Pyridine, Pyrrolo-Pyrimidine and Related Heterocyclic Compounds - Pyrrolo-pyridine, pyrrolo-pyrimidine and related heterocyclic compounds analogues of the formula:10-30-2008
200901769803-Substituted-6-Aryl Pyridines - 3-substituted-6-aryl pyridines of Formula I are provided:07-09-2009
20090239841Diaryl Ureas as CB1 Antagonists - Compounds of Formula I are provided. In which the variables are as described herein. Such compounds may be used to modulate CB1 activity in vivo or in vitro, and are particularly useful in the treatment of conditions responsive to CB1 modulation in humans, domesticated companion animals and livestock animals, including appetite disorders, obesity and addictive disorders. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies and various in vitro assays.09-24-2009
201000225164,5-Disubstituted-2-aryl pyrimidines - 4,5-disubstituted-2-arypyrimidines of Formula I and Formula II are provided:01-28-2010
20100216763Heteroaryl Amide Derivatives - Heteroaryl amide derivatives are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.08-26-2010
20100266509HETEROARYL AMIDE ANALOGUES AS P2X7 ANTAGONISTS - Heteroaryl amide analogues are provided, of Formula (I), wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.10-21-2010
20100267698Benzimidazole and Pyridylimidazole Derivatives - This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I10-21-2010
20110118273PYRROLO-PYRIDINE, PYRROLO-PYRIMIDINE AND RELATED HETEROCYCLIC COMPOUNDS - Pyrrolo-pyridine, pyrrolo-pyrimidine and related heterocyclic compounds analogues of the formula:05-19-2011
201101601873-aryl-5,6-disubstituted pyridazines - The present invention provides compounds of Formula (I) or (II) salt form or prodrug thereof, wherein variables are defined herein, that are modulators of metalloproteases such as matrix metalloproteases (MMPs) and ADAMs. The compounds or compositions described herein can be used to treat diseases associated with metalloprotease activity including, for example, arthritis, cancer, cardiovascular disorders, skin disorders, inflammation or allergic conditions.06-30-2011

Patent applications by Jun Yuan, Guilford, CT US