Patent application number | Description | Published |
20100160207 | Feedback Prodrug - Compounds and methods for use in selectively inhibiting a lytic enzyme based on feedback inhibition. The conjugated compound serves as a substrate for a lytic enzyme. Cleavage of the conjugated compound by the lytic enzyme releases an inhibitor of the enzyme. | 06-24-2010 |
20100297250 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS - 1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate. | 11-25-2010 |
20120040011 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS - 1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate. | 02-16-2012 |
20120058960 | FEEDBACK PRODRUG - Compounds and methods for use in selectively inhibiting a lytic enzyme based on feedback inhibition are described. The conjugated compound serves as a substrate for a lytic enzyme. Cleavage of the conjugated compound by the lytic enzyme releases an inhibitor of the enzyme. | 03-08-2012 |
20120172575 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS - 1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate. | 07-05-2012 |
20120208722 | SURFACE ENHANCED RAMAN SPECTROSCOPY PLATFORMS AND METHODS - Surface enhanced Raman spectroscopy (SERS) platforms and methods of making and using such platforms are disclosed herein. Such platforms can be made by immobilizing a biomaterial (e.g., a carbohydrate such as a glycan) by reacting an azide-functional group attached to a surface of a solid substrate with at least one cyclooctyne (e.g., a dibenzocyclooctyne) having a biomaterial or biomaterial binding group attached thereto. In certain embodiments the immobilized biomaterial can be detected using, for example, surface enhanced Raman spectroscopy. | 08-16-2012 |
20120322974 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS - 1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate. | 12-20-2012 |
20140054163 | METHODS FOR REACTING CYSTEINE RESIDUES IN PEPTIDES AND PROTEINS - Methods for labeling or modifying cysteine residues in proteins and/or enzymes are disclosed. The methods include the reaction of an o-naphthoquinone methide with a thiol group of a cysteine residue of a protein or enzyme, which can be reversible in preferred embodiments. The o-naphthoquinone methide can conveniently be generated by irradiation of a precursor compound, preferably in an aqueous solution, suspension, or dispersion. | 02-27-2014 |
Patent application number | Description | Published |
20100101368 | FUNCTIONALLY GRADED CEMENTED TUNGSTEN CARBIDE WITH ENGINEERED HARD SURFACE AND THE METHOD FOR MAKING THE SAME - A method for manufacturing functionally graded cemented tungsten carbide with hard and wear-resistant surface and tough core is described. The said functionally graded cemented tungsten carbide (WC—Co) has a surface layer having a reduced amount of cobalt. Such a hard surface and tough core structure is an example of functionally graded materials in which mechanical properties are optimized by the unique combination of wear-resistance and toughness. WC—Co with reduced-cobalt surface layer may be fabricated through a carburization heat treatment process following conventional liquid phase sintering. The graded WC—Co thus obtained contains no brittle η phase. | 04-29-2010 |
20110116963 | FUNCTIONALLY GRADED CEMENTED TUNGSTEN CARBIDE WITH ENGINEERED HARD SURFACE AND THE METHOD FOR MAKING THE SAME - A method of preparing a functionally graded cemented tungsten carbide material via heat treating a sintered cemented tungsten carbide is disclosed and described. The heat treating process comprises at least a step that heats the sintered material to the multi-phase non-equilibrium temperature range in which multiple phases including solid tungsten carbide, liquid metal binder, and solid metal binder coexist. Additionally, the material, after the heat treating process comprises a surface layer with lower metal binder content than the nominal value of metal binder content of the bulk of the material. | 05-19-2011 |
20130118308 | FUNCTIONALLY GRADED CEMENTED TUNGSTEN CARBIDE WITH ENGINEERED HARD SURFACE AND THE METHOD FOR MAKING THE SAME - A functionally graded cemented tungsten carbide material produced via heat treating a sintered cemented tungsten carbide is disclosed and described. The heat treating process comprises at least a step that heats the sintered material to the multi-phase temperature range in which multiple phases including solid tungsten carbide, liquid metal binder, and solid metal binder coexist. Additionally, the material, after the heat treating process comprises a surface layer with lower metal binder content than the nominal value of metal binder content of the bulk of the material. The material is used to make tools for rock drilling, machining of metal alloys, and machining of non-metallic materials. The material can also be used to make engineered wear parts that are used in mechanical systems and applications where wear resistance is required or desired. | 05-16-2013 |
Patent application number | Description | Published |
20090240474 | SYSTEM AND METHOD FOR GENERATING A MODEL OF AN IMAGE MEASURING MACHINE - A method for generating a model of an image measuring machine is disclosed. The method includes obtaining vertex coordinates of the image measuring machine and features that need to be generated from a configuration file stored in a storage device of a computer. The features comprise a top cover, a lens, a workplace, and a holder of the image measuring machine. The vertex coordinates comprise the vertex coordinates of the top cover, the lens, the workplace, and the holder. The method further includes generating the features of the top cover, the lens, the workplace, and the holder using graphical interfaces according to the corresponding vertex coordinates, so as to create the model of the image measuring machine, and displaying the model of the image measuring machine on a display device. | 09-24-2009 |
20100042921 | SYSTEM AND METHOD FOR VIEWING SOFTWARE HELP DOCUMENTATION - A system and method for viewing software help documentation obtains a feature name of a current interface of a software and a position of a cursor in the current interface, and receives a control command to invoke a help system of the software. The system and method further displays the help document of the help option corresponding to the position of the cursor in the current interface on a display device, in response to a determination that the help system comprises the feature name of the current interface, and further comprises a help option corresponding to the position of the cursor in the current interface. | 02-18-2010 |
20130037676 | FIXING APPARATUS FOR STORAGE DEVICE - An apparatus includes a board presenting a number of engaging portions and a post, and a matching casing containing a data storage device. The casing defines a number of engaging holes and a fixing member on one side. The fixing member includes a first sliding portion and a second sliding portion locating at opposite sides of the post which define a curving slot in which the post can slide. The fixing member is rotated to lock the casing to the board, and rotate back to unlock the casing from the board. | 02-14-2013 |
Patent application number | Description | Published |
20090108377 | Method for fabricating gate dielectrics of metal-oxide-semiconductor transistors using rapid thermal processing - In a method for fabricating gate dielectrics of metal-oxide-semiconductor transistors, rapid thermal processing (RTP) of a gate dielectric material is performed at a temperature from 1000-1200° C. in a low-concentration oxidizing gas. The method regrows an oxide layer having a thickness of more than 0.05 nm between the gate dielectric layer and the channel region that reduces gate leakage current by 2-5 orders of magnitude and improves hot-electron reliability due to phonon-energy-coupling enhancement (PECE) effect. | 04-30-2009 |
20120243661 | DATA ACQUIRED SYSTEM AND CT APPARATUS USING THE SAME - A data acquired system is provided. The data acquired system includes a main structure with a cavity formed therein, the cavity having a bottom for mounting a circuit board with electrical components thereto, a fan assembly disposed on the main structure, and an airflow guide disposed within the cavity and configured to guide airflow from the fan assembly for heat dissipation of the electrical components, the airflow guide positioned at a distance above the electrical components to form a gap between the airflow guide and the electrical components, wherein a sidewall of the cavity is provided with an air vent corresponding to the gap such that the airflow passes through the gap and is discharged from the air vent. | 09-27-2012 |
20120251634 | TRADITIONAL CHINESE DRUG COMPRISING DANSHEN EXTRACTS AND SANQI EXTRACTS AND USE THEREOF - The present invention discloses a traditional Chinese drug consisting of Danshen extract and Sanqi extract, the pharmaceutical composition comprising the above traditional Chinese drug as an active component and the use thereof. The traditional Chinese drug consists of Danshen extract and Sanqi extract in a weight ratio of (2˜6):(0.5˜2). The invention further discloses the effect of the above traditional Chinese drug and the pharmaceutical composition comprising the above traditional Chinese drug as an active component for treating cardiac microcirculation disorder and myocardial damage induced by ischemia/reperfusion. | 10-04-2012 |
20140138306 | TUBULAR OIL-WATER SEPARATOR AND SPIRAL FLOW GENERATOR THEREFOR - The present invention discloses a cyclone generator for a pipeline type oil-water separator which separates oil from water using the principle of cyclone. The cyclone generator comprises: flow deflectors which are fixedly arranged along the circumferential direction of a pipe to generate, when an oil-water mixture flows through the flow deflectors, a centrosymmetric cyclone field to centrifugally separate oil from water. The present invention further discloses an oil-water separation device which uses the aforementioned principle, the mixture of oil and water flowing through the device forms a centrosymmetric cyclone field in which an oil core is distributed in the central area of a pipe without shifting significantly so as to achieve an excellent oil-water separation effect. | 05-22-2014 |
20140146939 | X-RAY DETECTOR, COLLIMATOR, CT APPARATUS AND METHOD FOR THE SAME - An X-ray detector, a collimator, a CT apparatus and a method thereof are provided. The X-ray detector comprises a plurality of detector modules which are arranged in an array along a slice direction and a signal channel direction being orthogonal to each other, the array at least comprising a left detection area, a central detection area and a right detection area that are contiguous in the signal channel direction, wherein, in the slice direction, coverage of the left detection area and coverage of the right detection area are complementary and sum of these two coverages is equal to coverage of the central detection area. The collimator comprises a pair of moving shield plates and a fixing shield plate, wherein shape of a window in the fixing shield plate is the same as shape of the array. The CT apparatus comprises the X-ray detector and the collimator. | 05-29-2014 |
20140146948 | CT COLLIMATOR AND CT SYSTEM INCLUDING THE CT COLLIMATOR - A CT collimator comprising a rotating slot part on a rotation shaft and having a plurality of blades, each blade has a slot of a different width and a radiation beam entering the collimator can only pass via a slot in one of the blades, each edge of each blade slot along a longitudinal direction has a convex curved surface structure, and in a vertical plane along a longitudinal direction, two side edges of the slot are curved, and each blade is arranged to be eccentric to the center of the rotation shaft. A CT system using the CT collimator, the detection area of the radiation rays projected to the radiation detector via the CT collimator can be maintained unchanged by adjusting the rotation angle of the blade, under the circumstance where the focus of the radiation source shifts during a CT scan. | 05-29-2014 |
Patent application number | Description | Published |
20130073231 | IN-SITU DATA ACQUISITION SYSTEMS AND METHODS - Data acquisition systems and methods for acquiring test data associated with standard insulated power cables and/or power equipment such as switchgears, transformers, electric motors, etc are disclosed. The test data may then be subsequently analyzed for defects, such as the presence of faults, discharges (e.g., PD, coronas, arcing, etc.). The systems may store the acquired test data on removable, non volatile memory, such as Flash memory. The removable memory may be retrieved by an un-skilled technician periodically and returned to a lab or other test facility for subsequent analysis by highly trained analysts. | 03-21-2013 |
20130179100 | SYSTEM FOR ANALYZING AND LOCATING PARTIAL DISCHARGES - A sensor detects partial discharges (PDs) in an electrical power system and generates a corresponding analog electrical signal. A data acquisition component receives the signal from the sensor and converts it to digitized zero span data for a series of uniformly spaced frequencies in a frequency spectrum of interest. A digital signal processing component receives the digitized zero span data, analyzes such data, and generates a corresponding phase resolved spectrum signal in three dimensional format including dimensions of amplitude, phase and frequency for each of the uniformly spaced frequencies. A display component receives the analyzed data stream from the processing component and actuates one or more displays from which characteristics of the PD can be identified, such as different types of PDs from different sources, and information on the location of a PD relative to the sensor. | 07-11-2013 |