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Julio A.
Julio A. Aguirre-Ghiso, Niskayuna, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100249184 | INDUCTION AND/OR MAINTENANCE OF TUMOR DORMANCY BY DISRUPTION OF UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR-INTEGRIN INTERACTION - The present invention relates to a method of inducing cancer cells into dormancy and treating cancer in a subject. This method involves administering to a subject an effective amount of a compound that disrupts interaction between urokinase plasminogen activator receptor and integrin, thereby including cancer cells into dormancy and treating cancer in the subject. Also disclosed is a method of disrupting interaction between integrin and urokinase plasminogen activator receptor on cancer cells. The present invention also relates to a method of screening for compounds effective in inducing tumor dormancy and treating cancer in a subject. | 09-30-2010 |
Julio A. Camarero, Livermore, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100292104 | Photoswitchable Method for the Ordered Attachment of Proteins to Surfaces - Described herein is a method for the attachment of proteins to any solid support with control over the orientation of the attachment. The method is extremely efficient, not requiring the previous purification of the protein to be attached, and can be activated by UV-light. Spatially addressable arrays of multiple protein components can be generated by using standard photolithographic techniques. | 11-18-2010 |
Julio A. Garceran, Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20080197369 | Double flip semiconductor device and method for fabrication - A double flip-chip semiconductor device formed by a double flip fabrication process. Epitaxial layers are grown on a substrate in the normal fashion with the n-type layers grown first and the p-type layers grown subsequently. The chip is flipped a first time and mounted to a sacrificial layer. The original substrate is removed, exposing the n-type layer, and various additional layers and treatments are added to the device. Because the n-type layer is exposed during fabrication, the layer may be processed in various ways including adding a reflective element, texturing the surface or adding microstructures to the layer to improve light extraction. The chip is flipped a second time and mounted to a support element. The sacrificial layer is then removed and additional layers and treatment are added to the device. The finished device features a configuration in which the layers maintain the same orientation with respect to the support element that they had with the original substrate on which they were grown. Processing the n-type layers, rather than the p-type layers as in a single flip process, provides greater design flexibility when selecting features to add to the device. Thus, previously unavailable processes and reflective elements may be utilized, enhancing the external quantum efficiency of the device. | 08-21-2008 |
Julio A. Garceran, Dorham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110248836 | LIGHTING APPARATUS WITH ENCODED INFORMATION - A solid state emitter or emitter package has an associated information containing element including machine readable encoded information that may be indicative of or enable retrieval of information useful for operation and/or control of at least one emitter An information containing element may be dynamically updateable, and may receive signals from at least one sensor arranged to sense a condition or characteristic of an emitter device. Operation of at least one emitter may be adjusted responsive to sensed values and predeveloped operating settings correlated to such values to mitigate degradation of output characteristics. A lighting device such as a lamp or light fixture may include an information exchange element arranged to communicate with an information containing element of an emitter or emitter package. Operation of a lighting device may depend on authentication of an emitter by a lighting. | 10-13-2011 |
Julio A. Monjes, Tucson, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20090116980 | Air and water conditioner by two separated air flows - This device is a water adiabatic evaporative cooler of two separated air flows contained in a cylindrical body, there is the humid peripheral flow which comprises the components of the water evaporation system, the other is the central flow designated as the ambient dry flow where the air current produces the cooling effect. The two air flows are generated by a single axial air blower, the central zone of the air blower drives the atmospheric air through a central concentric body containing an air to water heat exchanger, this is the air to be directed to the controlled ambient, while the peripheral part of the single axial blower drives the air through an external annular adiabatic evaporation chamber, from here the cool condensed moisture goes to the heat exchanger while residual humid air is evacuated to the external atmosphere. | 05-07-2009 |