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Julie M.

Julie M. Cairney, Petersham AU

Patent application numberDescriptionPublished
20110277886NITRIDING OF NIOBIUM STEEL AND PRODUCT MADE THEREBY - A nitrided steel product or thin cast steel strip comprising, by weight, less than 0.25% carbon, between 0.20 and 2.0% manganese, between 0.05 and 0.50% silicon, less than 0.01% aluminum, niobium between 0.01 and about 0.20%, and between 0.01 and 0.075% nitrogen, and having a majority of the microstructure comprised of bainite and acicular ferrite, having more than 70% niobium in solid solution prior to nitriding and having yield strength between 650 MPa and 800 MPa and tensile strength between 750 MPa and 900 MPa.11-17-2011

Julie M. Cherrington, La Jolla, CA US

Patent application numberDescriptionPublished
20100323988SOLID CITRATE AND TARTRATE SALTS OF DPP-IV INHIBITORS - This invention relates to DPP-IV inhibitory citrate or tartrate salts of pyrrolidinylaminoacetyl pyrrolid acid compounds that are physically and chemically stable, substantially non-deliquescent solids under ambient conditions.12-23-2010

Julie M. Galante-Fox, Hemlock, NY US

Patent application numberDescriptionPublished
20080283632Fuel injector director plate having chamfered passages and method for making such a plate - An improved fuel injection spray director plate including conically chamfered entries to the flow passages through the plate. The conical chamfer may extend part way or all the way through the plate. In a currently preferred embodiment, the chamfer extends only part way through the plate, and the remaining cylindrical portion of the passage provides desirable directional capability for the spray. Preferably, the conical chamfer axis forms an angle with the cylindrical portion axis. Preferably, a flow passage is positioned in the director plate such that the main flow direction of fuel exiting the fuel injector valve is received into the chamfer of the passage. Preferably, a second conical portion is formed in the passage between the first conical portion and the cylindrical portion.11-20-2008

Patent applications by Julie M. Galante-Fox, Hemlock, NY US

Julie M. Hasenwinkel, Manlius, NY US

Patent application numberDescriptionPublished
20090239970MULTI-SOLUTION BONE CEMENTS AND METHODS OF MAKING THE SAME - The present invention relates to bone cements and, more particularly, to acrylic-based orthopedic bone cements, their use in spinal applications, and methods for making the same. An embodiment of the present invention provides multi-solution bone cements which include cross-linked PMMA beads, a linear polymer, and a monomer with various polymer to monomer ratios, and polymer bead to linear polymer ratios. The bone cement can include a polymer to monomer (P:M) ratio of between about 1:1 and 1.4:1, and can also include a polymer bead to linear polymer ratio of between about 1:1 and 2:1. Another embodiment of the present invention provides the use of a radiopacifier in the bone cement composition, such as ZrO09-24-2009
20100273911MULTI-SOLUTION BONE CEMENTS AND METHODS OF MAKING THE SAME - The present invention relates to bone cements and, more particularly, to acrylic-based orthopedic bone cements, their use in spinal applications, and methods for making the same. An embodiment of the present invention provides a method of grafting PMMA brushes on cross-linked PMMA nanospheres comprising at least one of the following steps: performing a hydrolysis reaction of surface methyl ester groups of said cross-linked PMMA nanospheres to form surface carboxylic acid groups of said cross-linked PMMA nanospheres; forming a 2-aminoethyl acrylate compound; coupling said surface carboxylic acid groups of said cross-linked PMMA nanospheres with said 2-aminoethyl acrylate compound to form a coupled compound with an initiating site; and grafting said PMMA brushes onto said initiating site. Another embodiment of the present invention includes an orthopedic bone cement including cross-linked PMMA nanospheres comprising PMMA brushes prepared by this method, and a monomer, wherein polymer to monomer ratio is between about 1:1 and 1.3:1.10-28-2010
20110212136Nanosphere/Microsphere Delivery System for the Treatment of Spinal Cord Injury - A formulation including injectable biodegradable nanospheres and/or microspheres as a delivery system for chondroitinase ABC (cABC) or a functional derivative of cABC to treat acute and chronic spinal chord injury in a mammal having the same is provided. The biodegradable nanosphere/microsphere formulation releases cABC or a functional derivative of cABC in a time-released manner at the site of the spinal cord injury. cABC infusion can promote axon regrowth and some behavioral recovery. The nanospheres and/or microspheres provided herein include cABC or a functional derivative of cABC loaded within and/or on a biodegradable polymer matrix. In some embodiments of the present invention, the surface of the biodegradable polymer matrix can be modified to target a specific scar site. In addition to providing a nanosphere formulation that include polymeric incorporated cABC, a method of treating a mammal having a spinal cord injury is also provided.09-01-2011

Patent applications by Julie M. Hasenwinkel, Manlius, NY US

Julie M. Kerkvliet, Otsego, MN US

Patent application numberDescriptionPublished
20120130158PEYRONIES TREATMENT DEVICE - A Peyronie's treatment device is described that is configured to treat an erect penis having curvature characterized by a first penis side with an unaffected length and a second penis side with an affected length that is shorter than the unaffected length. The device includes a band connected between a proximal support that is attachable to a base of a penis and a distal support that is attachable adjacent a corona of the penis. The band has an elastic material and a second material that is attached to the elastic material. The second material is provided to stop elongation of the elastic material at a length approximately equal to the affected length of the erect penis.05-24-2012

Julie M. Lee, Somerville, MA US

Patent application numberDescriptionPublished
20090156421ASSAYS AND METHODS FOR EVALUATING MULTIMERIC COMPLEXES - Assays, e.g., homogenous assays, and methods for identifying, quantifying and/or monitoring the formation and/or stability of a multimeric complex, e.g., a ternary complex are disclosed. The methods and assays of the invention can be used to identify and/or evaluate agents (e.g., proteins, peptides, antibody molecules, and small and large molecules) that interfere with and/or inhibit the formation of a multimeric complex (e.g., a ternary complex) or that disrupt a previously formed complex.06-18-2009

Julie M. Miwa, New York, NY US

Patent application numberDescriptionPublished
20100004162Lynx, a novel family of receptor ligands in the central nervous system, corresponding nucleic acids and proteins and uses thereof - The present invention provides a novel family of polypeptides which are ligand-gated channel receptor accessory molecules or ligands, denoted Lynx. This invention provides an isolated polypeptide comprising an amino acid sequence of a Lynx polypeptide in which the amino acid sequence is set forth in SEQ ID NO:2, SEQ ID NO:4 or SEQ ID NO:15, including fragments, mutants, variants, analogs, homologs, or derivatives, thereof. This invention further provides an isolated immunogenic polypeptide comprising an amino acid sequence of a Lynx polypeptide and relates to antibodies of Lynx polypeptides and the use of such antibodies. The invention provides an isolated nucleic acid encoding a polypeptide comprising an amino acid sequence of a Lynx polypeptide. This invention provides pharmaceutical compositions and diagnostic and therapeutic methods of use of the isolated polypeptides and nucleic acids of the present invention. Assays for compounds which mimic, alter or inactivate the polypeptides of the present invention for use in therapy are also provided. The present invention further relates to methods of isolating Lynx polypeptides and the nucleic acids encoding such polypeptides.01-07-2010

Julie M. Strizki, Yardley, PA US

Patent application numberDescriptionPublished
20100291034COMBINATIONS OF HCV PROTEASE INHIBITOR(S) AND CYP3A4 INHIBITOR(S), AND METHODS OF TREATMENT RELATED THERETO - Disclosed are medicaments, pharmaceutical compositions, pharmaceutical kits, and methods based on combinations comprising, separately or together: (a) a CYP3A4 inhibitor; and (b) a HCV protease inhibitor; for concurrent or consecutive administration in treating a human subject infected with HCV.11-18-2010
20110059154CCR5 ANTAGONISTS AS PROPHYLACTICS FOR PREVENTING HIV INFECTION AND METHODS OF INHIBITING TRANSMISSION OF SAME - Topical cream, ointment, lotion, gel, foam formulations and slow release formulations or devices are provided including certain CCR5 antagonists as prophylactics for the prevention, retardation or inhibition of transmission of Human Immunodeficiency Virus (HIV) infection from one human to another.03-10-2011

Patent applications by Julie M. Strizki, Yardley, PA US

Julie M. Werbitt, Broomfield, CO US

Patent application numberDescriptionPublished
20110173092PATRON SERVICE SYSTEM AND METHOD - A method provides for using a portable patron unit in a venue or in a vicinity of the venue. The method includes wirelessly connecting the patron unit to be in communication with the venue, and providing at least one display on the patron unit enabling a patron to place a patron order for at least one item or service provided by the venue. The method also includes displaying the patron order and a location of the patron unit on the patron unit and at least one portable staff unit, and updating a status of the patron order, and a location of the patron unit when the patron moves to a different location, on both the patron unit and the at least one staff unit. The method further includes indicating that the at least one item or service ordered has been completed on both the patron unit and the at least one staff unit when the at least one item or service ordered has been provided to the patron.07-14-2011