Patent application number | Description | Published |
20090275602 | Substituted hydroxyethyl amine compounds as beta-secretase modulators and methods of use - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I | 11-05-2009 |
20100222338 | BETA-SECRETASE MODULATORS AND METHODS OF USE - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I | 09-02-2010 |
20110118250 | BETA-SECRETASE MODULATORS AND METHODS OF USE - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I | 05-19-2011 |
20110251186 | Amino-Oxazines and Amino-Dihydrothiazine Compounds as Beta-Secretase Modulators and Methods of Use - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I | 10-13-2011 |
20110251190 | SPIRO-TETRACYCLIC RING COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and other related conditions. In one embodiment, the compounds have a general Formula I | 10-13-2011 |
20120220583 | SUBSTITUTED HYDROXYETHYL AMINE COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase activity and for the treatment of diseases, including Alzheimer's disease (AD) and related CNS conditions, mediated thereby. In one embodiment, the compounds have a general Formula I | 08-30-2012 |
20120329830 | Amino Heteroaryl Compounds as Beta-Secretase Modulators and Methods of Use - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I wherein ring A, B | 12-27-2012 |
20130018064 | Amino Heteroaryl Compounds as Beta-Secretase Modulators and Methods of UseAANM Paras; Nick A.AACI San FranciscoAAST CAAACO USAAGP Paras; Nick A. San Francisco CA USAANM Cheng; YuanAACI Newbury ParkAAST CAAACO USAAGP Cheng; Yuan Newbury Park CA USAANM Powers; TimothyAACI MalibuAAST CAAACO USAAGP Powers; Timothy Malibu CA USAANM Brown; JamesAACI MoorparkAAST CAAACO USAAGP Brown; James Moorpark CA USAANM Hitchcock; Stephen A.AACI JupiterAAST FLAACO USAAGP Hitchcock; Stephen A. Jupiter FL USAANM Judd; TedAACI Simi ValleyAAST CAAACO USAAGP Judd; Ted Simi Valley CA USAANM Lopez; PatriciaAACI West HillsAAST CAAACO USAAGP Lopez; Patricia West Hills CA USAANM Xue; QiufenAACI Newbury ParkAAST CAAACO USAAGP Xue; Qiufen Newbury Park CA USAANM Yang; BryantAACI Simi ValleyAAST CAAACO USAAGP Yang; Bryant Simi Valley CA US - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I, wherein ring A, B | 01-17-2013 |
Patent application number | Description | Published |
20090248301 | POSITION ESTIMATION FOR NAVIGATION DEVICES - A method of providing position estimation with a navigation device comprises periodically recording magnetic field strength of an area substantially surrounding a navigation device as a user of the navigation device traverses a select pathway. The method combines the recorded magnetic field strength with measurements from at least a dead reckoning portion of the navigation device to provide position estimates along the select pathway. The method further corrects each of the position estimates from a starting position on the select pathway, where each of the corrected position estimates have an error value below one or more previous position estimates and any intervening positions between each of the one or more previous position estimates and the starting position, with the error value corresponding to an error threshold based on the previous position estimates. | 10-01-2009 |
20090267592 | SYSTEMS AND METHODS FOR DETERMINING ENTRY OF A NAVIGATION SYSTEM INTO A STRUCTURE - Systems and methods are operable to determine that a navigation system has entered a structure. An exemplary embodiment monitors a magnetic field at an outdoor position, monitors a magnetic field at a current position, compares a characteristic of the monitored magnetic field at the current position with a corresponding characteristic of the outdoor magnetic field, and determines entry into the structure at least as a function of a change in the determined characteristic of the monitored magnetic field from the corresponding characteristic of the outdoor magnetic field. | 10-29-2009 |
20090295376 | MAGNETIC ODOMETER WITH DIRECTION INDICATOR SYSTEMS AND METHODS - Systems and methods for determining a directional movement of an object such as a wheeled vehicle. The system includes a magnet having a north pole and a south pole mounted to the object, a single magnetic sensor positioned such that the sensor can individually detect each magnetic pole as the object moves, the sensor configured to produce a first characteristic signal when a north pole is detected and a second characteristic signal when a south pole is detected, and a processing device in signal communication with the sensor, the processing device configured to determine a directional movement of the object based on a configuration of a signal doublet that includes the first and second characteristic signals. The methods include sensing the north and south poles as they pass the magnetic sensor and determining a direction based on an order in which the north and south poles are sensed. | 12-03-2009 |
20100277292 | METHOD FOR AUTOMATIC STANDBY RESPONSE TO REDUCE PILOT WORKLOAD - A method of communication comprises receiving a text message, starting a response timer, and monitoring transmission of a response message. If the response message has not been transmitted, it is determined whether the response timer has reached a timing threshold. If not, monitoring for transmission of the response message continues. If the response timer reaches the timing threshold without the response message being sent, it is determined whether an automatic standby message mode is enabled. If the automatic standby message mode is enabled, a STANDBY message is automatically transmitted and the response timer is restarted. Monitoring for response message transmission then continues. If a response message has not been transmitted, it is determined whether the response timer expired. If response timer has not expired, then monitoring response message transmission continues. If the response timer has expired without the response message being sent, transmission of subsequent response messages is disabled. | 11-04-2010 |
20110066392 | SYSTEMS AND METHODS FOR CALIBRATION OF GYROSCOPES AND A MAGNETIC COMPASS - Calibration systems and methods simultaneously calibrate a magnetic compass and gyroscopes. An exemplary embodiment rotates the field calibration system. Based upon the rotation sensed by the magnetic compass and the gyroscopes, the field calibration system determines compensation for both the magnetic compass and the gyroscopes. | 03-17-2011 |
20110066395 | SYSTEMS AND METHODS FOR GYROSCOPE CALIBRATION - Systems and methods may be used to determine gain compensation and/or bias compensation for gyroscopes in the field where access to specialized calibration tools is limited. | 03-17-2011 |
20120173139 | POSITION ESTIMATION FOR NAVIGATION DEVICES - A method of providing position estimation with a navigation device comprises periodically recording magnetic field strength of an area substantially surrounding a navigation device as a user of the navigation device traverses a select pathway. The method combines the recorded magnetic field strength with measurements from at least a dead reckoning portion of the navigation device to provide position estimates along the select pathway. The method further corrects each of the position estimates from a starting position on the select pathway, where each of the corrected position estimates have an error value below one or more previous position estimates and any intervening positions between each of the one or more previous position estimates and the starting position, with the error value corresponding to an error threshold based on the previous position estimates. | 07-05-2012 |