| Patent application number | Description | Published |
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| 20090084607 | DRILL BITS AND TOOLS FOR SUBTERRANEAN DRILLING - A drill bit includes at least one extension pad extending rotationally forward or backward of an associated blade in a gage region of the bit body. The extension pad includes a circumferential bearing surface that extends the circumferential bearing surface of the associated blade and reduces the chordal drop between any blade having an extension pad associated therewith and a circumferentially adjacent blade toward which the extension pad protrudes. A drill bit that reduces a chordal drop segment extending across a junk slot is also disclosed. | 04-02-2009 |
| 20110155472 | EARTH-BORING TOOLS HAVING DIFFERING CUTTING ELEMENTS ON A BLADE AND RELATED METHODS - Earth-boring tools include combinations of shearing cutting elements and gouging cutting elements on a blade of the earth-boring tools. In some embodiments, a gouging cutting element may be disposed adjacent to a shearing cutting element on a blade of an earth-boring tool. Methods of forming earth-boring tools include providing such combination of at least one shearing cutting element and at least one gouging cutting element on a blade of an earth-boring tool. | 06-30-2011 |
| 20110192651 | SHAPED CUTTING ELEMENTS ON DRILL BITS AND OTHER EARTH-BORING TOOLS, AND METHODS OF FORMING SAME - Earth-boring tools include a body, one or more blades projecting outwardly from the body, and cutting elements carried by the blade. The cutting elements include at least one shearing cutting element and at least one gouging cutting element. Methods of forming an earth-boring tool include mounting a shearing cutting element comprising an at least substantially planar cutting face to a body of an earth-boring tool, and mounting a gouging cutting element comprising a non-planar cutting face to the body of the earth-boring tool. The gouging cutting element may be positioned on the body of the earth-boring tool such that the gouging cutting element will gouge formation material within a kerf cut in the formation material by the shearing cutting element, or between kerfs cut in the formation material by a plurality of shearing cutting elements. | 08-11-2011 |
| 20110253452 | CORING APPARATUS AND METHODS - A coring apparatus is provided, which apparatus, in one exemplary embodiment, includes a rotatable member coupled to a drill bit configured to drill a core from a formation, a substantially non-rotatable member in the rotatable member configured to receive the core from the formation, and a sensor configured to provide signals relating to rotation between the rotatable member and the substantially non-rotatable member during drilling of the core from the formation, and a circuit configured to process the signals from the sensor to estimate rotation between the rotatable member and the non-rotatable member. | 10-20-2011 |
| 20110266070 | CUTTING ELEMENTS, EARTH-BORING TOOLS, AND METHODS OF FORMING SUCH CUTTING ELEMENTS AND TOOLS - Cutting elements include a volume of superabrasive material. The volume of superabrasive material comprises a front-cutting surface, an end-cutting surface, a cutting edge, and lateral side surfaces extending between and intersecting each of the front-cutting surface and the end-cutting surface. An earth-boring tool may comprise a bit body and at least one cutting element attached to the bit body. Methods of forming cutting elements comprise forming a volume of superabrasive material comprising forming a front-cutting surface, an end-cutting surface, a cutting edge, and lateral side surfaces extending between and intersecting each of the front-cutting surface and the end-cutting surface. Methods of forming earth-boring tools comprise forming a cutting element and attaching the cutting element to an earth-boring tool. | 11-03-2011 |
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| 20100081624 | SELECTIVE PEPTIDES THAT INHIBIT THE BIOLOGICAL ACTIVITY OF CALCINEURIN - The invention relates to the biotechnology sector involving the area of human health. More specifically, the invention is based on the surprising usefulness of peptides LxVPc1, c3 and c4 as efficient selective inhibitors of the calcineurin signalling pathway (CN)-NFAT and the phosphate activity of CN. Said compounds are useful immunosuppressors and serve as a base for the preparation of therapeutic compositions for the prophylactics and treatment of human diseases associated with T-lymphocyte activation, including, but not limited to, autoimmune diseases, inflammation and allergy or transplant rejections. In addition, said peptides and the associated biological and genetic material can form useful tools for the development of tests that can be used to find compounds that have a selective antagonist activity in relation to CN. | 04-01-2010 |
| 20120076809 | METHOD TO INHIBIT THE BIOLOGICAL ACTIVITY OF CALCINEURIN WITH SELECTIVE PEPTIDES - The invention relates to the biotechnology sector involving the area of human health. More specifically, the invention is based on the surprising usefulness of peptides LxVPc1, c3 and c4 as efficient selective inhibitors of the calcineurin signalling pathway (CN)-NFAT and the phosphate activity of CN. Said compounds are useful immunosuppressors and serve as a base for the preparation of therapeutic compositions for the prophylactics and treatment of human diseases associated with T-lymphocyte activation, including, but not limited to, autoimmune diseases, inflammation and allergy or transplant rejections. In addition, said peptides and the associated biological and genetic material can form useful tools for the development of tests that can be used to find compounds that have a selective antagonist activity in relation to CN. | 03-29-2012 |
