Patent application number | Description | Published |
20120321583 | Protein-Polymer-Drug Conjugates - A drug conjugate is provided herein. The conjugate comprises a protein based recognition-molecule (PBRM) and a polymeric carrier substituted with one or more -L | 12-20-2012 |
20130101546 | Protein-Polymer-Drug Conjugates - A drug conjugate is provided herein. The conjugate comprises a protein based recognition-molecule (PBRM) and a polymeric carrier substituted with one or more -L | 04-25-2013 |
20130309192 | Auristatin Compounds and Conjugates Thereof - Auristatin compounds and conjugates thereof are provided herein. The conjugate comprises a protein based recognition-molecule (PBRM) and a polymeric carrier substituted with one or more -L | 11-21-2013 |
20140017265 | Terminally Modified Polymers and Conjugates Thereof - A terminally modified polymer is provided herein. At least one terminus of the polymer is —O—(CH | 01-16-2014 |
20140134127 | Protein-Polymer-Drug Conjugates - A drug conjugate is provided herein. The conjugate comprises a protein based recognition-molecule (PBRM) and a polymeric carrier substituted with one or more -L | 05-15-2014 |
20150044160 | PROTEIN-POLYMER-DRUG CONJUGATES - A drug conjugate is provided herein. The conjugate comprises a protein based recognition-molecule (PBRM) and a polymeric carrier substituted with one or more -L | 02-12-2015 |
20150064130 | PROTEIN-POLYMER-DRUG CONJUGATES - Auristatin compounds and conjugates thereof are provided herein. The conjugate comprises a protein based recognition-molecule (PBRM) and a polymeric carrier substituted with one or more -L | 03-05-2015 |
20150104407 | PROTEIN-POLYMER-DRUG CONJUGATES - A polymeric scaffold useful for conjugating with a protein based recognition-molecule (PBRM) to form a PBRM-polymer-drug conjugate is described herein. The scaffold includes one or more terminal maleimido groups. Also disclosed is a PBRM-polymer-drug conjugate prepared from the scaffold. Compositions comprising the conjugates, methods of their preparation, and methods of treating various disorders with the conjugates or their compositions are also described. | 04-16-2015 |