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Joseph, US
Abner Joseph, Carmel, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20100025270 | BIOSENSOR CONTAINER - A biosensor container comprising a housing defining an internal glucose test strip compartment. The housing has an engagement portion for retaining a detachable means for storing data, and the means for storing data has data stored thereon specific to a batch of glucose test strips. At least one of the housing and the means for storing data includes at least one data reading element that is externally accessible when the means for storing data is retained by the engagement portion of the housing. The container includes various fail safe features to prevent mishandling and insure the user obtains the correct results. The housing includes means for connecting to the bG meter only when the means for storing data is retained by the housing. The housing further includes means for dispensing glucose test strips only when the housing is in either of an attached-to meter mode or a stand-alone mode. In the attached-to-meter mode the means for storing data is retained by the housing and the housing is connected to a bG meter. In the stand-alone mode the means for storing data is detached from the housing and the housing is not connected to the bG meter. | 02-04-2010 |
Abner Joseph, Camel, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20110186428 | ELECTRODE ARRANGEMENTS FOR BIOSENSORS - The present invention relates to a biosensor. The biosensor includes a support substrate, electrodes positioned on the support substrate, a spacer substrate positioned on the support substrate, and a cover positioned on the spacer substrate. The cover cooperates with the support substrate to define a capillary channel. The electrodes include at least one working electrode defining a working electrode area in the capillary channel. The working electrode is configured to minimize variation in the working electrode area in the capillary channel due to variations in the spacer substrate placement relative to the working electrode. | 08-04-2011 |
Abner D. Joseph, Carmel, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20110132778 | TEST ELEMENT CODING APPARATUSES, SYSTEMS AND METHODS - Certain exemplary embodiments include a test element operable to receive a sample and to provide an indication of an analyte of the sample to a meter. In one form test element comprises a substrate and an optically readable pattern provided on the substrate which encodes information relating to the test element. | 06-09-2011 |
| 20110174644 | TEST STRIP CONTAINER WITH STRIP RETAINER AND METHODS OF MANUFACTURING AND UTILIZATION THEREOF - A test strip container with an insert comprising a channel and a retaining member and methods of manufacturing and utilization thereof are disclosed. The container includes a housing, an insert, a lid, and at least one retaining member in at least one channel. The at least one retaining member releasably retains a plurality of test strips in the at least one channel. | 07-21-2011 |
| 20110263006 | INTEGRATED TEST STRIP CONTAINER WITH RETAINING INSERT - A blood glucose meter for providing easy access to test strips and measuring blood glucose, a disposable and removable cartridge for providing easy access to test strips, and methods of manufacturing and utilization thereof are disclosed. The blood glucose meter for providing easy access to test strips and measuring blood glucose has a disposable and removable cartridge, a retaining member which releasably retains the test strips in a stacked configuration, and a housing. The disposable and removable cartridge has a rigid lid attached to a flexible body. | 10-27-2011 |
Abner David Joseph, Carmel, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20090010802 | METHOD FOR MANUFACTURING A STERILIZED LANCET INTEGRATED BIOSENSOR - An integrated disposable includes a test strip and a lancet packet coupled to the test strip. The lancet packet includes a sterility sheet enclosing at least a portion of a lancet to maintain the sterility of the lancet. The lancet packet and the sterility sheet, in particular, allow the lancet to be sterilized separately from the test strip. The lancet in one form is incorporated into a lancet tape that is sterilized in a continuous, reel-to-reel sterilization process. The lancet tape in one form is sterilized using an electron beam sterilization process. With electron beam sterilization, sterilization is enhanced by irradiating both sides of the tape with electron beams. Sterilization can adversely affect chemical reagents in the test strip. To alleviate this chemistry degradation issue, the lancet packet is attached to the test strip after the lancet is sterilized. | 01-08-2009 |
| 20090277923 | DISPENSER FOR FLATTENED ARTICLES - A substantially moisture-proof, airtight dispenser for both storing and dispensing several flattened articles such as diagnostic test strips. The inventive dispenser includes a novel pivotable housing that a user need merely grab and squeeze to eject a test strip. Independent movement of the user's fingers to push a button or turn a knob is unnecessary to dispense a strip, which makes the present invention well suited for diabetics suffering from nerve damage in their extremities and other complications resulting from the disease. The invention includes a novel flexible arm member and pusher head that engage and push an article from the dispenser as the two parts of the housing are pivoted together. The articles are dispensed through an exit that is configured with a novel flexible seal that maintains the dispenser substantially airtight. Several inventive seal embodiments and methods of making the same are disclosed. | 11-12-2009 |
| 20100021342 | METHOD AND APPARATUS FOR LIGHTED TEST STRIP - A test strip with a sample chamber is secured to a meter. The sample chamber in the portion of the test strip that extends out of the meter is illuminated by transmitting light from a light source inside the meter internally through the test strip towards the sample chamber. By way of analogy, the test strip acts in a fashion similar to a fiber optic cable or optical wave guide by transmitting the light from the meter to the remotely located sample chamber that extends outside the meter. The user is then able to easily see the sample chamber of the test strip in dark conditions so that the user is able to readily align the sample chamber with the drop of fluid on the skin as well as view the sample chamber in order to ensure proper filling. The light also illuminates a test strip slot into which the test strip is inserted. | 01-28-2010 |
Ajay Joseph, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090213846 | SYSTEM AND METHOD FOR VOICE OVER INTERNET PROTOCOL (VoIP) AND FACSIMILE OVER INTERNET PROTOCOL (FoIP) CALLING OVER THE INTERNET - A system and method for sending Long distance telephone calls over the Internet utilizes cost and quality of service data to optimize system performance and to minimize the cost of completing the calls. The system utilizes a network of gateways connected to the Internet. The gateways receive calls from various service providers and convert the analog calls into data packets which are then placed onto the Internet. Similarly, the gateways take data packets off the Internet, convert the data packets back into analog format, and provide the analog telephone calls to the same or another service provider. Then system periodically checks the quality of communications between each of the gateways, and uses this information, in combination with cost information, to determine how to route the calls over the Internet. Special addressing protocols can be used by a system embodying the invention to reduce or eliminate unnecessary signaling between gateways as call setup procedures are carried out. The system can also use information about calls that has been recorded in more than one location to determine how much to charge for completing a call. | 08-27-2009 |
| 20090238175 | SYSTEM AND METHOD FOR VOICE OVER INTERNET PROTOCOL (VoIP) AND FACSIMILE OVER INTERNET PROTOCOL (FoIP) CALLING OVER THE INTERNET - A system and method for sending long distance telephone calls over the Internet utilizes cost and quality of service data to optimize system performance and to minimize the cost of completing the calls. The system utilizes a network of gateways connected to the Internet. The gateways receive calls from various service providers and convert the analog calls into data packets which are then placed onto the Internet. Similarly, the gateways take data packets off the Internet, convert the data packets back into analog format, and provide the analog telephone calls to the same or another service provider. Then system periodically checks the quality of communications between each of the gateways, and uses this information, in combination with cost information, to determine how to route the calls over the Internet. Special addressing protocols can be used by a system embodying the invention to reduce or eliminate unnecessary signaling between gateways as call setup procedures are carried out. The system can also use information about calls that has been recorded in more than one location to determine how much to charge for completing a call. | 09-24-2009 |
Alan Joseph, Chesterfield, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110141779 | Boost Multilevel Inverter System - A boost inverter includes a first capacitor for connection in parallel with a dc supply voltage; a second capacitor connected in series with the first capacitor; an energy transfer path including a transfer capacitor and switches connected to the transfer capacitor for cyclically transferring energy from the first capacitor to the transfer capacitor and then from the transfer capacitor to the second capacitor; a multilevel inverter circuit connected in parallel with the series combination of the first and second capacitors, the inverter having at least one phase output for connection to an electric motor; and a PWM controller that activates the energy transfer path when a desired peak-to-peak output voltage exceeds the dc supply voltage and deactivates the energy transfer means when the desired peak-to-peak output voltage is less than the dc supply voltage. | 06-16-2011 |
Albert F. Joseph, Charleston, WV US
| Patent application number | Description | Published |
|---|---|---|
| 20090258943 | Hybrid strategies for reducing leaching of metal biocides from biodegradable substrates - Hybrid strategies generally involve treating biodegradable substrates with preservative compositions having at least two phases in which the metal biocide is distributed among at least the two phases and via equilibrium reactions moves between the two phases. Both phases are caused to contact the substrate in a manner so that the phases are in contact with each other during at least a portion of the treatment. In illustrative embodiments, the first phase is a liquid phase comprising complexed metal biocide dissolved in a liquid carrier, while the second phase comprises particles comprising the metal biocide, often precipitated and/or colloidal particles. The strategies and related compositions, processes, and treatments are hybrid in the sense that the strategies include both heterogeneous (insoluble) and homogeneous metal biocide constituents. Unlike heterogeneous strategies, hybrid strategies are less sensitive to particle size constraints and may use biocide particles with a wider range of particle sizes. Unlike homogeneous strategies, hybrid strategies are less sensitive to pH and may use a wider range of complexing agents, including mildly alkaline amines such as triethanolamine. | 10-15-2009 |
| 20100016426 | Post-impregnation treatments to improve distribution of metal biocides in an impregnated substrate - The present invention relates to post-treatment compositions and methods useful for modifying the distribution of metal biocide(s) in biodegradable substrates such as wood, other cellulosic products, starch-based products, and the like that are vulnerable to decay due to insects, fungi, microbes, and the like. The compositions include complexing agents of moderate strength that are able to facilitate mobilization and redistribution of metal biocide(s) in substrates without undue leaching. The compositions can be used, for example, to redistribute the metal biocide(s) into depleted regions of a substrate by redistribution of metal biocide from other regions of the substrate. Post-treatment compositions that include additional metal biocide can also replenish these regions with the freshly supplied, additional biocide. Thus, the depleted regions can be restored by redistribution and/or replenishment mechanisms. Service life of substrates in the field benefits by these post-treatments as a consequence. | 01-21-2010 |
| 20110091575 | STRATEGIES FOR REDUCING LEACHING OF WATER-SOLUBLE METAL BIOCIDES FROM TREATED WOOD PRODUCTS - Strategies that dramatically reduce leaching of water-soluble metal-containing biocides from treated biodegradable products. Aqueous, preservative compositions of the present invention incorporate one or more water-soluble metal species having biocidal activity and one or more agents that increase the leaching resistance of these metal species when impregnated into biodegradable products. Using one or more of these agents allows usage rates of the biocide impregnants to be dramatically lowered at the time of impregnation of the products. Because less of the metal biocide leaches in the presence of these agent(s), less biocide has to be added in order to meet desired loading goals. Generally, an agent of the present invention that reduces leaching of metal biocides is water soluble, is substantially nonionic in aqueous media, has a molecular weight greater than about 100, and has a vapor pressure less than that of water at standard temperature. Preferred agents are those including at least 10 weight percent, more preferably at least 16 weight percent, and even more preferably at least 20 weight percent oxygen. Examples of these preferred agents include (poly)ethers and/or nonionic surfactants including one or more oxyalkylene units in the backbone and/or as substituents of the molecule. | 04-21-2011 |
Alvin Joseph, Williston, VT US
| Patent application number | Description | Published |
|---|---|---|
| 20100032809 | METAL WIRING STRUCTURE FOR INTEGRATION WITH THROUGH SUBSTRATE VIAS - An array of through substrate vias (TSVs) is formed through a semiconductor substrate and a contact-via-level dielectric layer thereupon. A metal-wire-level dielectric layer and a line-level metal wiring structure embedded therein are formed directly on the contact-via-level dielectric layer. The line-level metal wiring structure includes cheesing holes that are filled with isolated portions of the metal-wire-level dielectric layer. In one embodiment, the entirety of the cheesing holes is located outside the area of the array of the TSVs to maximize the contact area between the TSVs and the line-level metal wiring structure. In another embodiment, a set of cheesing holes overlying an entirety of seams in the array of TSVs is formed to prevent trapping of any plating solution in the seams of the TSVs during plating to prevent corrosion of the TSVs at the seams. | 02-11-2010 |
| 20110185330 | METAL WIRING STRUCTURE FOR INTEGRATION WITH THROUGH SUBSTRATE VIAS - An array of through substrate vias (TSVs) is formed through a semiconductor substrate and a contact-via-level dielectric layer thereupon. A metal-wire-level dielectric layer and a line-level metal wiring structure embedded therein are formed directly on the contact-via-level dielectric layer. The line-level metal wiring structure includes cheesing holes that are filled with isolated portions of the metal-wire-level dielectric layer. In one embodiment, the entirety of the cheesing holes is located outside the area of the array of the TSVs to maximize the contact area between the TSVs and the line-level metal wiring structure. In another embodiment, a set of cheesing holes overlying an entirety of seams in the array of TSVs is formed to prevent trapping of any plating solution in the seams of the TSVs during plating to prevent corrosion of the TSVs at the seams. | 07-28-2011 |
Alvin A. Joseph, Williston, VT US
| Patent application number | Description | Published |
|---|---|---|
| 20100032796 | Integrated Circuit Structure, Design Structure, and Method Having Improved Isolation and Harmonics - Disclosed are embodiments of a semiconductor structure, a design structure for the semiconductor structure and a method of forming the semiconductor structure. The embodiments reduce harmonics and improve isolation between the active semiconductor layer and the substrate of a semiconductor-on-insulator (SOI) wafer. Specifically, the embodiments incorporate a trench isolation region extending to a fully or partially amorphized region of the wafer substrate. The trench isolation region is positioned outside lateral boundaries of at least one integrated circuit device located at or above the active semiconductor layer of the SOI wafer and, thereby improves isolation. The fully or partially amorphized region of the substrate reduces substrate mobility, which reduces the charge layer at the substrate/BOX interface and, thereby reduces harmonics. Optionally, the embodiments can incorporate an air gap between the wafer substrate and integrated circuit device(s) in order to further improve isolation. | 02-11-2010 |
Andrew H. Joseph, Milford, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20080252643 | Method and system for developing a strategy for use in a controller and storage medium for storing instructions which effectuate the method - A method and system for developing a strategy for use in a controller and storage medium for storing instructions which effectuate the method are provided. A computer graphical approach of at least one embodiment of the invention eliminates computer programming by presenting a user with a blank 2-dimensional graph on a computer screen along with X and Y axes. Using available toolbars and palettes, the user drags appropriate graphical objects into the graph. Each object represents an operation to perform data analysis or monitoring such as: data acquisition, data transformation or operating limits. | 10-16-2008 |
B. Anthony Joseph, Bellevue, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100070501 | ENHANCING AND STORING DATA FOR RECALL AND USE USING USER FEEDBACK - A user of a computing device may see an item of interest she would like to remember for future reference. The user captures data of the item of interest and submits it to a memory enhancement service for enhancement and storage. The service submits the captured data to a human interaction task system which distributes the captured data to one or more human workers which to identify the item of interest, determine the user's interest in the item, and provide information regarding the item based on this determined interest. To facilitate the enhancement process, the user may add indications to the captured data prior to submission. Alternatively or additionally, the service may electronically submit queries to the user. The enhanced data returned from the human interaction task system is then stored by the memory enhancement service for subsequent recall by the user and possible use by the user. | 03-18-2010 |
Boby Joseph, Shrewsbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090003535 | IP-Based Enhanced Emergency Services Using Intelligent Client Devices - Providing enhanced emergency services (E-911) to an IP Telephony-based PBX or similar system, by utilizing aspects of the intelligence of end-user SIP client devices to address challenges and difficulties associated with E-911-like services in LAN-based telephony environments. | 01-01-2009 |
| 20110142062 | iSCSI to FCoE Gateway - Transparent communication between iSCSI and FCoE end nodes is provided by a gateway device having iSCSI and FCoE network interfaces. The gateway allows end nodes of one protocol to communicate with end nodes of another protocol as if they were communicating with end nodes of the same protocol. The gateway accomplishes this by creating “ghost” end nodes for each protocol. For example, the gateway creates ghost iSCSI nodes corresponding to physical FCoE nodes, and ghost FCoE nodes corresponding to physical iSCSI nodes. A ghost end node of a particular protocol is able to communicate with native end nodes of that protocol as if it were a native end node, because the gateway translates packets sent from end nodes in their native protocol into the other protocol for receipt by corresponding ghost nodes, and vice versa. | 06-16-2011 |
Body Joseph, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110267986 | IP-BASED ENHANCED EMERGENCY SERVICES USING INTELLIGENT CLIENT DEVICES - Providing enhanced emergency services (E-911) to an IP Telephony-based PBX or similar system, by utilizing aspects of the intelligence of end-user SIP client devices to address challenges and difficulties associated with E-911-like services in LAN-based telephony environments. | 11-03-2011 |
Carla Natasha Joseph, Trevose, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090145454 | INTERCHANGEABLE HEADBAND - A headband includes a hair band and a band insert. The hair band has a generally arcuate configuration with opposed free ends. The hair band defines a hair contacting surface positionable against a wearer's head, an opposed outer surface, and an aperture extending therethrough. The band insert is adapted to be releasably mounted into the aperture of the hair band. | 06-11-2009 |
Celestine Joseph, Snoqualmie, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100235345 | INDIRECT DATABASE QUERIES WITH LARGE OLAP CUBES - A large OLAP cube includes data and dimensions not required for a particular query, or for a collection of queries. A response to a query is generated by using the large OLAP cube rather than using an OLAP cube tailored to the query, and rather than querying the relational database directly. The large OLAP cube may be created after identifying a set of frequently sought data and/or filters used in queries to the relational database. Data may be staged by creating a smaller OLAP cube with data extracted from the large OLAP cube. The cubes may then be queried, browsed, and used to prepare reports or generate flat files. | 09-16-2010 |
Christopher W. Joseph, Pineville, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100147893 | EASY SHIFT DUAL-MODE PISTOL-GRIP GREASE GUN - A dual mode pistol grip grease gun that operates in either the volume mode or the pressure mode. The grease gun includes a cylinder head having a handle attached thereto. Attached to the cylinder head via a shiftable link is a lever, which has a slot at one end. The shiftable link is disposed in the slot of the lever, and its position therein defines whether the grease gun is in the volume or the pressure mode. The shape of the slot is such that, when the grease gun is in volume mode and when the lever is fully pressed toward the handle, an angle defined by a first axis (defined as a line connecting a pivot point of a connection of the link to the cylinder head and a pivot point of a connection of the link to an end of the slot defining volume mode) and a second axis (defined as a line connecting the pivot point of the connection of the link to the end of the slot defining volume mode and a point along a bottom curve of the slot where the concavity of the curve changes) is approximately ten degrees. The shape of the slot, roller and tabs on the link allow for ease of shifting. | 06-17-2010 |
Claudine Joseph, Phoenix, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20100064219 | Network Hosted Media Production Systems and Methods - Embodiments provide systems and methods to create new media. Collaborating users can create new media using a network hosted media production functionality of an embodiment. In one embodiment, a network hosted media production system can be used to create new media, wherein the system includes a sound library component, a video component, a live input component, a sequencer component, and a synchronization component. | 03-11-2010 |
Daniel D. Joseph, Minneapolis, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20100024282 | NANO-DISPERSIONS OF COAL IN WATER AS THE BASIS OF FUEL RELATED TECHNOLOGIES AND METHODS OF MAKING SAME - Colloidal coal-in-water slurries having nano-particles of coal creating a pseudo-fluid. The colloidal coal-in-water slurry generally includes from about fifty to about seventy two weight percent of coal, with about 20 to about 80 percent of the coal having a particle size of about one micron or less with a mode particle size of about 250 nanometers. The coal-in-water slurry can also include a surfactant system containing one surfactant or mixtures of two or more surfactants, or mixtures of one or more surfactants and an inorganic or organic salt. The coal-in-water slurry can be used in low NOx burner applications as the main fuel and/or the reburn fuel, in gasification processes as the input fuel either alone, or in combination with organic materials, in gas turbine applications, and in diesel engine applications. | 02-04-2010 |
| 20110203163 | NANO-DISPERSIONS OF COAL IN WATER AS THE BASIS OF FUEL RELATED TECHNOLOGIES AND METHODS OF MAKING SAME - Colloidal coal-in-water slurries having nano-particles of coal creating a pseudo-fluid. The colloidal coal-in-water slurry generally includes from about fifty to about seventy two weight percent of coal, with about 20 to about 80 percent of the coal having a particle size of about one micron or less with a mode particle size of about 250 nanometers. The coal-in-water slurry can also include a surfactant system containing one surfactant or mixtures of two or more surfactants, or mixtures of one or more surfactants and an inorganic or organic salt. The coal-in-water slurry can be used in low NOx burner applications as the main fuel and/or the reburn fuel, in gasification processes as the input fuel either alone, or in combination with organic materials, in gas turbine applications, and in diesel engine applications. | 08-25-2011 |
David J. Joseph, Glendale, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20100107326 | UNIVERSAL FIT BEDPAN PAD - A bedpan pad ( | 05-06-2010 |
Dinakaran B. Joseph, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20080320147 | METHOD AND APPARATUS FOR POLICY-BASED PACKET CLASSIFICATION - A method, apparatus, and computer implemented instructions for processing a request in a data processing system. The request is received. In response to a first hash value being present within the request, the first hash value is compared to a second hash value that was computed locally, wherein the second hash value represents a current policy configuration for assigning a quality of service. In response to a match between the first hash value and the second hash value, other information in the request is used to establish a quality of service for packets associated with the request. | 12-25-2008 |
Douglas J. Joseph, Danbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080256180 | USE OF HARDWARE TO MANAGE DEPENDENCIES BETWEEN GROUPS OF NETWORK DATA PACKETS - A task obtained by a communications processor is decomposed into one or more requests that form a request group. The requests of the request group are sent to main memory and responses to those requests are expected. There may be requests for a plurality of request groups being processed concurrently. However, responses to the request groups are to be returned to the communications processor in the order in which the request groups were sent from the communications processor. To ensure this ordering, dependencies between the request groups are tracked by hardware coupled to the communications processor. | 10-16-2008 |
| 20100146369 | Soft Error Protection in Individual Memory Devices - Techniques are disclosed for minimizing the effects of soft errors associated with memory devices that are individually accessible. By way of example, a method of organizing a column in a memory array of a memory device protected by an error correction code comprises the step of maximizing a distance of the error correction code by maximizing a physical distance between memory bits associated with a memory line within the column protected by the error correction code. Other soft error protection techniques may include use of a feed forward error correction code or use of a memory operation (e.g., read or write operation) suppress and retry approach. | 06-10-2010 |
| 20100179989 | USE OF HARDWARE TO MANAGE DEPENDENCIES BETWEEN GROUPS OF NETWORK DATA PACKETS - A task obtained by a communications processor is decomposed into one or more requests that form a request group. The requests of the request group are sent to main memory and responses to those requests are expected. There may be requests for a plurality of request groups being processed concurrently. However, responses to the request groups are to be returned to the communications processor in the order in which the request groups were sent from the communications processor. To ensure this ordering, dependencies between the request groups are tracked by hardware coupled to the communications processor. | 07-15-2010 |
Douglas James Joseph, Danbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090267238 | BRIDGES FOR INTERCONNECTING INTERPOSERS IN MULTI-CHIP INTEGRATED CIRCUITS - A structure and a method for forming the same. The structure includes a substrate, a first interposer on the substrate, a second interposer on the substrate, and a first bridge. The first and second interposers are electrically connected to the substrate. The first bridge is electrically connected to the first and second interposers. | 10-29-2009 |
| 20100094870 | METHOD FOR MASSIVELY PARALLEL MULTI-CORE TEXT INDEXING - There is provided, in a parallel pipelined structure on a multi-core device, a method for parallel pipelined multi-core indexing. The method includes generating one or more single document indexes respectively corresponding to one or more single documents of a given data stream. The method further includes generating one or more multi-document interval-based hash tables from the one or more single document indexes. The method also includes generating a global hash table formed from merging one or more of the multi-document interval-based hash tables, the global hash table representing a collective index for all of the single documents for which the one or more single document indexes were generated. | 04-15-2010 |
Edward T. Joseph, Inver Grove Heights, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20110046574 | CLOTTING CASCADE INITIATING APPARATUS AND METHODS OF USE AND METHODS OF CLOSING WOUNDS - A wound closure apparatus is provided which utilizes blood fluid by activating the clotting cascade of blood fluid outside the body within a substantially enclosed sterile container then introducing the blood fluid to the wound site to complete clotting. An apparatus for providing ways of inhibiting anticoagulating agents and slowing fibrin clot degradation are also disclosed. Kits for practicing the invention singularly or in combination with and/or associated with preferred procedures are also disclosed. The invention provides a clotting cascade initiation apparatus including a substantially enclosed sterile containment chamber within which an aliquot of blood fluid, either autologous or from donor sources, can be received and retained. In preferred embodiments, the sterile containment chamber further includes a heparin binding agent which will bind heparin and remove it from the blood fluid. In further embodiments, the containment chamber will also include a procoagulating agent, wherein a clotting cascade can be initiated when the blood fluid is accepted into the sterile containment chamber. | 02-24-2011 |
Elaine Joseph, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110301042 | METHODS OF SAMPLE ENCODING FOR MULTIPLEX ANALYSIS OF SAMPLES BY SINGLE MOLECULE SEQUENCING - The invention generally relates to methods for sequencing a plurality of nucleic acids from different samples. In certain embodiments, methods of the invention provide contacting a nucleic acid duplex including a primer nucleic acid hybridized to a template nucleic acid with a polymerase enzyme in the presence of a first detectably labeled nucleotide under conditions that permit the polymerase to add nucleotides to the primer in a template-dependent manner, in which a unique oligonucleotide sequence is attached to the template nucleic acid so that the template nucleic acid may be differentiated from other template nucleic acid molecules, detecting a signal from the incorporated labeled nucleotide, and sequentially repeating the contacting and detecting steps at least once, wherein sequential detection of incorporated labeled nucleotide determines the sequence of the nucleic acid. | 12-08-2011 |
Elango G. Joseph, Peoria, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090248545 | Related parts identification and sales tool - A method of identifying related parts is disclosed. The method includes receiving a selection of a product, receiving a selection of at least one part of a product, and identifying at least one related part structurally associated with the selected at least one part. The method further includes generating a parts list containing the selected at least one part and the identified at least one related part, and presenting the parts list. | 10-01-2009 |
Erat S. Joseph, Baton Rouge, LA US
| Patent application number | Description | Published |
|---|---|---|
| 20110254275 | Portable wave-swash & coastal-wind energy harvester - In accordance with the present invention, a portable wave-swash & coastal-wind energy harvester, placed on a sea coast in swash zone captures energy contained in coastal waves and in coastal-wind through the utilization of wave turbines, wind turbines, and wave floats. Wave-float levers carrying wave floats and wave turbines, swing and maintain lower halves of wave turbines below water always. A gear system with one-way clutches transmits torque to an alternator to generate electricity. Flywheels maintain steady rotation of alternator shaft. A buoyancy chamber at the bottom produces reduction of weight of the unit when buoyancy chamber is emptied of water, and thereby enhances maneuverability of unit in water. Stabilization tanks at the top when filled with water provide extra weight and stability of the unit in its operating location. Units linked together in an energy farm combine their energy while forming a seawall-like barrier offering protection against coastal erosion. | 10-20-2011 |
Eric David Joseph, Chandler, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20090251213 | METHOD FOR ADJUSTING THRESHOLD VOLTAGE AND CIRCUIT THEREFOR - A method and circuit for changing a threshold voltage of a transistor. The circuit includes a sense circuit coupled to a switching transistor, a circuit transistor and to one terminal of a resistor. The other terminal of the resistor is connected to a body contact. The switching transistor directs current along one of two different paths in response to an input voltage sensed by the sense circuit. When the switching transistor directs a first current along one path, the first current is steered towards the resistor and flows through the resistor in one direction and when the switching transistor directs a second current along the other path, the second current is directed towards the resistor and flows through the resistor in the opposite direction from the first current. Steering the currents varies the potential of a body with respect to the potential at the source of the circuit transistor. | 10-08-2009 |
| 20100176883 | METHOD FOR ADJUSTING THRESHOLD VOLTAGE AND CIRCUIT THEREFOR - A method and circuit for changing a threshold voltage of a transistor. The circuit includes a sense circuit coupled to a switching transistor, a circuit transistor and to one terminal of a resistor. The other terminal of the resistor is connected to a body contact. The switching transistor directs current along one of two different paths in response to an input voltage sensed by the sense circuit. When the switching transistor directs a first current along one path, the first current is steered towards the resistor and flows through the resistor in one direction and when the switching transistor directs a second current along the other path, the second current is directed towards the resistor and flows through the resistor in the opposite direction from the first current. Steering the currents varies the potential of a body with respect to the potential at the source of the circuit transistor. | 07-15-2010 |
Eugene G. Joseph, Blacksburg, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20110027760 | DENTAL FILLING COMPOSITION COMPRISING ACIDIC POLYMER COMPOUND AND METHOD OF USING THE SAME - Compositions comprising an acidic polymer compound and a (meth)acrylic copolymer prepared from reactants comprising at least one aliphatic, aromatic, or aralkyl (meth)acrylate monomer and at least one ethylenically unsaturated monomer having a polar group or a siloxane group, and dental filling compositions comprising the composition, and methods of using the compositions | 02-03-2011 |
| 20110045444 | DENTAL FILLING COMPOSITION COMPRISING HYPERBRANCHED COMPOUND - Compositions comprising a hyperbranched compound and a polymer prepared from reactants comprising at least one (meth)acrylate monomer, and dental filling compositions comprising a hyperbranched compound. | 02-24-2011 |
| 20110135921 | Antistatic Block Copolymer Pressure Sensitive Adhesives and Articles - An antistatic pressure sensitive adhesive composition, useful in electronic and optical display applications, comprising an antistatic agent and a first block copolymer comprising at least two hard A block polymeric units each independently having a Tg of at least 50° C., and at least one soft B block (meth)acrylic polymeric unit having a Tg no greater than 20° C. The composition can comprise a second block copolymer. Articles comprising an antistatic pressure sensitive adhesive composition adjacent a first surface of a substrate. | 06-09-2011 |
| 20110135922 | Adhesive Compositions with Multiple Tackifiers - Adhesive compositions and articles that contain these adhesive compositions are described. More particularly, the adhesive compositions include (a) a block copolymer prepared from monoethylenically unsaturated monomers and (b) a tackifier mixture. The adhesives compositions can be adhered to many substrates including those having a non-polar surface. | 06-09-2011 |
| 20110256338 | FILMS HAVING STRUCTURED SURFACE AND METHODS FOR MAKING THE SAME - A film, and method of producing, wherein the film ( | 10-20-2011 |
Eugene G. Joseph, Vadnais Heights, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20080200587 | PRESSURE-SENSITIVE ADHESIVE CONTAINING ACICULAR SILICA PARTICLES CROSSLINKED WITH POLYFUNCTIONAL AZIRIDINES - An adhesive composition comprising an emulsion polymer which comprises a (meth)acrylate copolymer, and acicular silica particles, crosslinked by a polyfunctional aziridine crosslinking agent is described. | 08-21-2008 |
| 20080213584 | 2-OCTYL (METH)ACRYLATE ADHESIVE COMPOSITION - A pressure sensitive adhesive composition comprising a 2-octyl (meth)acrylate/(meth)acrylic acid copolymer is described. The adhesive composition may be derived from renewable resources and provides good peel, shear and high temperature stability. | 09-04-2008 |
Fellows Joseph, Salt Lake City, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20110288648 | CERAMIC TO CERAMIC JOINT AND ASSOCIATED METHODS - The present invention provides a ceramic to ceramic joint and methods for making such a joint. Generally, the joint includes a first ceramic part and a second ceramic part, wherein the first and second ceramic parts each include a ceramic-carbide or a ceramic-nitride material. In some cases, an aluminum-initiated joint region joins the first and second ceramic parts. This joint region typically includes chemical species from the first and second ceramic parts that have diffused into the joint region. Additionally, the first and second ceramic parts each typically include a joint diffusion zone that is disposed adjacent to the joint region and which includes aluminum species from the joint region that have diffused into the joint diffusion zone. Other implementations are also described. | 11-24-2011 |
Gregory A. Joseph, Naperville, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090264257 | Stride adjustment mechanism - In an elliptical step exercise apparatus a dynamic link mechanism can be used to vary the stride length of the machine. A control system can also be used to vary stride length as a function of various exercise and operating parameters such as speed and direction as well as varying stride length as a part of a preprogrammed exercise routine such as a hill or interval training program. In addition the control system can use measurements of stride length to optimize operation of the apparatus. | 10-22-2009 |
| 20090292216 | Noise cancellation mechanism - In a biometric sensor provided for use with an exercise apparatus and having a pair electrodes for sensing a biopotential signal, a common-mode rejection circuit can be used to cancel noise in the signal resulting from various sources including motion of the apparatus. | 11-26-2009 |
Jacob Joseph, Little Rock, AR US
| Patent application number | Description | Published |
|---|---|---|
| 20100204254 | Use of statins in the prevention and treatment of radiation injury and other disorders associated with reduced endothelial thrombomodulin - The present invention discloses statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) consistently and significantly increased endothelial cell thrombomodulin protein and functional activity. Statins also abrogated the downregulation of thrombomodulin that occurs in response to radiation injury. These results indicate that preserving or restoring endothelial thrombomodulin expression and function by statins may be useful in a variety of disorders associated with widespread endothelial dysfunction such as sepsis, adult respiratory distress syndrome, and normal tissue radiation injury. | 08-12-2010 |
James A. Joseph, Plymouth, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090069444 | Method to Ameliorate Oxidative Stress and Improve Working Memory Via Pterostilbene Administration - Disclosed is a pharmaceutical composition for treating oxidative stress comprising a therapeutically effective amount of a substantially pure compound of pterostilbene and a physiologically acceptable carrier. Pterostilbene is administered in an amount between about 2.5 mg to about 10 mg per kilogram of subject body weight. Also disclosed is a method for increasing a working memory of a subject, the method comprising administrating an effective amount of a substantially pure compound of pterostilbene, wherein the working memory for a subject increase and the therapeutic effectiveness is about 10 mg of pterostilbene per kilogram of subject body weight. | 03-12-2009 |
Jasen R. Joseph, Warren, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100230939 | Air Bag Chute Seal - An integrated air bag chute structure that provides sealing of an air bag aperture in an instrument panel substrate during a foam-in-place process. The structure provides an extended flange with flexible tapered edges that surround the aperture. The tapered edges are compressed against the upper surface of the substrate to seal and surround the substrate aperture when the chute structure is inserted into and retained in the substrate aperture. The air bag chute structure further defines a door support panel with pre-weakened molded edges and a hinge which are all integrally connected to the structure and flange without gaps that would allow for leakage during the foam-in-place process. | 09-16-2010 |
Jean Joseph, Oak Park, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20110215622 | CHAIR SLIP COVER - A seat cover for use with a chair is disclosed herein. The seat cover comprises a fabric cover, which has a back pocket, a seat form and a skirt portion. The seat cover also comprises a back form which has a front pad, a top pad, a first side pad, a second side pad and a first space defined by the front pad, the top pad, the first side pad and the second side pad. The seat cover further comprises a seat pad and a slip barrier. | 09-08-2011 |
John Joseph, Carson City, NV US
| Patent application number | Description | Published |
|---|---|---|
| 20100303113 | Multibeam Arrays of Optoelectronic Devices for High Frequency Operation - A VCSEL array device formed of a monolithic array of VCSELs and short circuited mesas is disclosed. The VCSELs can be spaced symmetrically or asymmetrical, in a manner to improve power or speed, or in phase and in parallel. The VCSELs are connected to a first metal contact pad formed on a heat-spreading substrate. The short-circuited mesas are formed alongside the VCSELs and are bonded to and form a short circuit to a second metal contact pad on the grounding substrate. Each VCSEL is encompassed by a thick metal heat sink to increase the height of VCSEL mesas. The structure of the heat sink, the VCSELs and the shorting mesas reduce parasitic impedance thereby increasing output power and high frequency response. The VCSELs and shorting mesas can be packaged as a coplanar waveguide in a ground-signal-ground configuration that improves signal modulation characteristics. | 12-02-2010 |
| 20110176567 | MULTIBEAM ARRAYS OF OPTOELECTRONIC DEVICES FOR HIGH FREQUENCY OPERATION - A VCSEL array device formed of a monolithic array of raised VCSELs on an electrical contact and raised inactive regions connected to the electrical contact. The VCSELs can be spaced symmetrically or asymmetrically, in a manner to improve power or speed, or in phase and in parallel. The VCSELs include an active region positioned between two mirrors generating a pulsed light operating at a frequency of at least 1 GHz. The VCSELs having an output power of at least 120 mW. The raised VCSELs and raised inactive regions are positioned between the electrical contact and an electrical waveguide. | 07-21-2011 |
John H. Joseph, Huntingtown, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100034054 | Enviromentally Assisted Processor in Sonar - An environmentally assisted processor that includes an environmental characterization module, an echo prediction module and an acoustic consistency module. The environmental characterization module obtains surrounding environmental characteristics, and provides inputs of the surrounding environmental characteristics to the echo prediction module. The echo prediction module utilizes the surrounding environmental characteristics to predict echo waveforms of would be targets in that particular local environment. The acoustic consistency module compares an observed echo waveform with predicted echo waveforms, if they are similar the observed echo waveform is determined to be from a target. | 02-11-2010 |
John R. Joseph, Carson City, NV US
| Patent application number | Description | Published |
|---|---|---|
| 20110148328 | SYSTEM AND METHOD FOR COMBINING LASER ARRAYS FOR DIGITAL OUTPUTS - Embodiments comprise a device that can efficiently produce a highly resolved intensity profile that can be easily switched to various specific configurations with binary word strings defining output intensities that after summation will be combined to form a single colors intensity depth. Arraying these devices allows an image line of single color pixels to be efficiently produced without gross scintillation effects. The non-coherent output is desirable in this application as it reduces scintillation effects on the screen or final image. | 06-23-2011 |
| 20110279903 | OPTICAL BEAM BUNDLE COMBINER FOR MULTIPLE LASER ARRAYS - One or more combiner elements are disclosed for optically combining multiple laser beam bundles, either extra-cavity or intra-cavity to the laser generating array chips, to form higher density bundles of parallel laser beams. The combiner elements can be shared between two or more array chips and include a form of a pellicle combiner, a polarizing beam splitter cube combiner, or some combination of the two devices. | 11-17-2011 |
Joy Joseph, New Berlin, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20090214437 | In Vivo Mitochondrial Labeling Using Positively-Charged Nitroxide Enhanced and Gadolinium Chelate Enhanced Magnetic Resonance Imaging - A system and method for acquiring MR imaging data from a subject includes administering positively-charged nitroxides or gadolinium chelates for in vivo mitochondrial labeling, acquiring MR imaging data from the subject, and reconstructing an image of the subject having enhanced contrast in areas including metabolic and/or mitotic activity. | 08-27-2009 |
| 20110059922 | MITOCHONDRIA TARGETED CATIONIC ANTI-OXIDANT COMPOUNDS FOR PREVENTION, THERAPY OR TREATMENT OF HYPER-PROLIFERATIVE DISEASE, NEOPLASIAS AND CANCERS - The inventions disclosed include methods of treating cancers and related neoplasias, especially prostate cancer, with pharmaceutically acceptable salts comprising lipophilic cation moieties linked to nitroxide or linked to hydroxylamine anti-oxidant groups. | 03-10-2011 |
Krummel Joseph, Rising Sun, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20080268733 | COATED MULTI-THREAT MATERIALS AND METHODS FOR FABRICATING THE SAME - According to some aspects, a method of manufacturing a coated multi-threat fabric, including providing a first fabric layer having a first surface, the first fabric layer having a plurality of high performance fibers, applying a first polymeric material onto the first surface of the first fabric layer, the polymeric material having a melt flow index of between about 0.7 to 1400 g/10 min, a Shore D hardness of between about 36 and 75, and ultimate tensile strength of between about 5 and 75 MPa, spreading the first polymeric material onto the first surface of the first fabric layer so as to form a raw coated fabric having a first coating layer, and heating the raw coated fabric to bond the first coating layer to the first fabric layer, wherein the first polymeric material is selected such that the coated multi-threat fabric is flexible enough to be stored on a roll of a predetermined size. In some aspects, a coated multi-threat fabric includes at least one layer of fabric, each layer having a plurality of high performance fibers, and at least one coating of polymeric material bonded to the at least one layer of fabric, the polymeric material comprising an ethylene acrylic acid copolymer selected to allow the coated multi-threat fabric to be stored on a roll of a predetermined size. | 10-30-2008 |
Kuriacose Joseph, Gaithersburg, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110261959 | METHOD AND APPARATUS FOR REMOTELY INSERTING WATERMARK INTO ENCRYPTED COMPRESSED VIDEO BITSTREAM - A method and apparatus for remote watermarking of a media program is disclosed. The method inserts a pattern of substituted second versions of media program portions that are invisible to the viewer, into reproduced copies of the media program. The method permits the watermarking of encrypted media programs. | 10-27-2011 |
Luke Joseph, Honolulu, HI US
| Patent application number | Description | Published |
|---|---|---|
| 20100268094 | Consumer electronic camera photoplethysmograph - A body part is placed on or near a consumer electronic device camera. The camera senses periodic light variations. A program analyses variations in images captured by the digital camera to determine pulse rate or breathing rate. | 10-21-2010 |
Michael Joseph, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100006467 | STORAGE CONTAINER - A storage container assembly includes a first lid and a base. The first lid includes a first lid structure. The base includes an upper edge, a base structure, and an opening. The upper edge of the base is configured to receive the first lid such that the first lid is mounted to the base. The base structure of the base is configured to mate with a second lid structure of a second lid such that the base is capable of being mounted to the second lid. The opening of the base allows the base to be accessible while the first lid is mounted to the base. | 01-14-2010 |
Michael Joseph, Milton, VT US
| Patent application number | Description | Published |
|---|---|---|
| 20100082369 | Systems and Methods for Interconnected Personalized Digital Health Services - Certain embodiments provide systems and methods for providing personalized, interconnected digital health services. Certain embodiments provide a digital health services system. The system includes an access portal providing access to health information for a patient from a plurality of clinical data sources. The system also includes a shared registry and repository storing information from the plurality of clinical data sources for interconnection and access via the access portal. The system further includes digital health information and services generating a personalized care plan for the patient based on health information from the shared registry and repository in conjunction with one or more rules applied to the health information to match the care plan with the health information for the patient and to track patient outcomes based upon compliance with the recommended care plan. | 04-01-2010 |
Michael F. Joseph, Milton, VT US
| Patent application number | Description | Published |
|---|---|---|
| 20080208625 | XDS Registry and Repository for Multiple Affinity Domains - Certain embodiments of the present invention provide a health information system. The health information system includes a hub, first affinity domain, and a second affinity domain. The hub includes a registry, a data repository, and a patient identity manager. Each of the first and second affinity domains includes a data sharing source and a data query source. | 08-28-2008 |
Paul J. Joseph, Lawrenceville, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20100307786 | Packaging For Micro Electro-Mechanical Systems And Methods Of Fabricating Thereof - Embodiments of the present disclosure provide systems and methods for producing micro electro-mechanical device packages. Briefly described, in architecture, one embodiment of the system, among others, includes a micro electro-mechanical device formed on a substrate layer; and a thermally decomposable sacrificial structure protecting at least a portion of the micro electro-mechanical device, where the sacrificial structure is formed on the substrate layer and surrounds a gas cavity enclosing an active surface of the micro electro-mechanical device. Other systems and methods are also provided. | 12-09-2010 |
Paul Jayachandran Joseph, Lawrenceville, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20090107952 | Sacrificial Compositions And Methods Of Fabricating A Structure Using Sacrificial Compositions - Compositions, methods of use thereof, and methods of decomposition thereof, are provided. One exemplary composition, among others, includes a polymer and a catalytic amount of a negative tone photoinitiator. | 04-30-2009 |
| 20090120905 | Sacrificial Compositions And Methods Of Fabricating A Structure Using Sacrificial Compositions - Compositions, methods of use thereof, and methods of decomposition thereof, are provided. One exemplary composition, among others, includes a polymer and a catalytic amount of a negative tone photoinitiator. | 05-14-2009 |
Paul Jayachandran Joseph, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20100112277 | Microstructures and methods of fabrication thereof - Microstructures and methods of fabricating microstructures are disclosed. One exemplary microstructure, among others, includes a substrate, an overcoat layer disposed upon the substrate, an air-region within at least a portion of the overcoat layer, and a framing material layer engaging at least a portion of the air-region on the inside of the framing material layer and engaging the overcoat layer on the outside of the framing material layer. | 05-06-2010 |
Pierre Joseph, Hamilton, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090062176 | Foamable Compositions - Foamable compositions are disclosed. The compositions contain one or more active ingredients combined with a foaming agent and optionally one or more surface tension adjusting agents. The foaming agent may comprise, for instance, a derivatized dimethicone. The surface tension adjusting agent, on the other hand, comprises a chemical species that either increases or decreases the surface tension of the composition within a desired range so that the composition is readily foamable. In this manner, active ingredients can be incorporated into the compositions that are typically hard to foam. Such ingredients include cleaning solvents and various skin care agents. Of particular advantage, foamable compositions can be formulated in accordance with the present disclosure that contain relatively small amounts of water such as less than about 20 percent by weight, such as less than about 10 percent by weight. In other embodiments, the composition can be completely anhydrous. | 03-05-2009 |
| 20090123504 | OLIVE OIL FORMULATION FOR PAIN RELIEF - The present disclosure generally relates to methods and compositions for reducing inflammation and/or pain, and more particularly, to compositions comprising an NSAID and oleocanthal and/or a related compound. The compositions are particularly suitable for topical delivery and may be used to relieve the effects of arthritis. | 05-14-2009 |
Raji E. Joseph, Ames, IA US
| Patent application number | Description | Published |
|---|---|---|
| 20080247953 | METHODS AND COMPOSITIONS FOR AFFECTING SUBSTRATE DOCKING OF KINASES IN MODULATING CELLULAR ACTIVITIES - The present invention relates to drug screening assays, therapeutic protocols and pharmaceutical compositions designed to target non-receptor tyrosine family kinases and components of the tyrosine kinase family signal transduction pathways. This includes primarily diseases or conditions associated with immune responses and can include treatment for cancers as well as various immune disorders. The invention reports a novel substrate SH2 domain docking mechanism apart from the kinase active site that is required for appropriate tyrosine phosphorylation by these tyrosine kinases. | 10-09-2008 |
| 20090010911 | METHODS AND COMPOSITIONS FOR AFFECTING CYCLOPHILIN A REGULATION OF KINASES IN MODULATING CELLULAR ACTIVITIES - The present invention relates to drug screening assays, therapeutic protocols and pharmaceutical compositions designed to target non-receptor tyrosine family kinases and components of the tyrosine kinase family signal transduction pathways. It has been previously reported by the inventors that a substrate SH2 domain docking mechanism apart from the kinase active site is required for appropriate tyrosine phosphorylation by these tyrosine kinases. According to the invention, it has been discovered that Cyclophilin A, the target of drugs such as cyclosporin A, mediates its regulatory effects by interacting with this remote SH2 domain, making modulation of this interaction possible for regulation and improved therapeutic intervention. | 01-08-2009 |
Richard Joseph, Stoughton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100233696 | METHODS, FLOW CELLS AND SYSTEMS FOR SINGLE CELL ANALYSIS - A method, flow cell and/or device for increasing the recovery of a limiting analyte in a sample, e.g., for single molecule analysis is disclosed. Methods for preparing a nucleic acid sample from a single cell and capturing nucleic acids on a surface configured for use in or with single molecule analysis are also provided. | 09-16-2010 |
| 20100233697 | METHOD FOR STANDARIZING SURFACE BINDING OF A NUCLEIC ACID SAMPLE FOR SEQUENCING ANALYSIS - Methods are described which enable nucleic acid sample standardization prior to anchoring to a surface, especially useful in single molecule nucleic acid sequencing applications when sample is limiting or unamplified. | 09-16-2010 |
Rose M. Joseph, Westford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100041031 | Optoelectronic detection system - The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples. | 02-18-2010 |
Sajan Joseph, Indianapolis, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20090221633 | INHIBITORS OF AKT (PROTEIN KINASE B) - 4-[5-(2-Amino-ethanesulfonyl)-isoquinolin-7-yl]-phenol or a pharmaceutically acceptable salt thereof or a hydrate of the compound or the salt thereof as Akt inhibitors that are antineoplastic and/or antiviral agents as well as compositions comprising these compounds and methods of using these compounds. | 09-03-2009 |
Silfred Joseph, St. Thomas, VI US
| Patent application number | Description | Published |
|---|---|---|
| 20100230419 | Food and drink tray - Food and drink trays have flat surfaces and peripheral edges with openings adapted for receiving and securely carrying a plurality of beverage and food containers. A bearing member attachable to a tray has an arched configuration and fits over the forearm of a user, while a gripping member attachable to the tray is adapted for gripping by a user's hand. A second embodiment has a pair of large circular openings on the upper surface that will hold full plates of food. The food and drink carrying tray may be made from wood, or from a lightweight material, such as plastic, and is useful for holding a plurality of beverages and plates of food when dining buffet-style in a restaurant or a home dinner party. Additional embodiments have removable grips and removable bearing members, as well as large food trays capable of receiving a variety of container-holding adapters. | 09-16-2010 |
Stephen Laurence Joseph US
| Patent application number | Description | Published |
|---|---|---|
| 20080245036 | Systemization method for recycling plastic bags and other items - A recycling method whereby a plastic bag or other recyclable item that satisfies applicable manufacturing specifications and is part of a recycling program is marked with a logo and a recycling bag that is part of the same recycling program is marked with a matching logo. Consumers discard plastic bags or the other recyclable items bearing the logo by depositing them in recycling bags bearing the matching logo. The filled recycling bags are subsequently collected for recycling. The system enables consumers to identify qualifying plastic bags and other qualifying recyclables instantaneously and reliably and provides a simple and easily learnable method for their disposal. The system also keeps qualifying plastic bags and other qualifying recyclables segregated from the rest of the waste and recycling streams and protects them from becoming contaminated. | 10-09-2008 |
Thomas J. Joseph, Commerce, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20090288434 | Air Conditioning Circuit Control Using a Thermostatic Expansion Valve and Sequence Valve - A valve assembly for an air conditioning system includes a liquid line port pressurized at a discharge pressure, an evaporator inlet port pressurized at a suction pressure, a sequence valve for controlling a first flow path between the liquid line port and an outlet in response to a differential between the discharge pressure and the suction pressure, and a thermostatic expansion valve that includes an actuator and an expansion valve member for controlling a second flow path between the outlet and the evaporator inlet port in response to a pressure differential across the actuator. | 11-26-2009 |
Timothy Joseph, Hollidaysburg, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090135371 | PROCESS FOR THE MANUFACTURE OF SPECTACLE LENSES - The invention provides methods for eliminating sharp edges that typically result during the production of uncut lenses. | 05-28-2009 |
Wael R. Joseph, Appleton, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20080272332 | MICROENCAPSULATED HEAT DELIVERY VEHICLES - Microencapsulated delivery vehicles comprising an active agent are disclosed. In one embodiment, the microencapsulated delivery vehicles are heat delivery vehicles capable of generating heat upon activation. The microencapsulated heat delivery vehicles may be introduced into wet wipes such that, upon activation, the wet wipe solution is warmed resulting in a warm sensation on a user's skin. Any number of other active ingredients, such as cooling agents and biocides, can also be incorporated into a microencapsulated delivery vehicle. | 11-06-2008 |
| 20090065521 | WET WIPES DISPENSING SYSTEM - The present disclosure relates to wet wipe dispensing systems for dispensing wet wipes capable of changing temperature upon use. In one embodiment, the dispensing system includes a wet wipe container and a lotion container that is held in assembly with the wet wipe container that contains a lotion that is kept separate from the wet wipes until the wet wipe is dispensed from the wet wipe container. The lotion includes a microencapsulated delivery vehicle that contains a temperature change agent that is capable of generating a temperature change upon contact with an aqueous solution. Once the wet wipe is dispensed from the system, an applicating device can apply the lotion to the wet wipe to facilitate contact between the temperature change agent in the microencapsulated delivery vehicle and the aqueous solution of the wet wipe. | 03-12-2009 |
| 20090220616 | MOISTURIZING AND LUBRICATING COMPOSITIONS - The present invention is generally directed to moisturizing and lubricating compositions for use on the bodyfacing surface of an absorbent product or on one or both faces of a tissue product. The moisturizing and lubricating compositions comprise an emollient, a humectant, and immobilizing agent and a compatibilizing agent. Optionally, the moisturizing and lubricating compositions can comprise a dispersing agent. | 09-03-2009 |
| 20110022015 | MULTILAYER ABSORBENT ARTICLE - An article has a body facing engagement surface for contacting a wearer's tissue layer. The body facing engagement surface has a first state adapted to inhibit movement of the article with respect to the tissue layer of the wearer, and a second state adapted to enhance movement of the article with respect to the tissue layer. The body facing engagement surface is adapted to transform from the first state to the second state upon application of a force greater than a threshold force. The body facing engagement surface has a gripping component and a sliding component wherein the gripping component overlies the sliding component in the first state. The gripping component is disposed for engaging and gripping the tissue layer in the first state until a force greater than the threshold force is encountered which transforms the engagement surface to promote relative sliding motion between the engagement surface and the tissue layer. | 01-27-2011 |
| 20110022016 | MULTILAYER ABSORBENT ARTICLE - A contact layer has an engagement surface adapted to contact a user's tissue layer. The contact layer is constructed so that the engagement surface has a first state adapted to inhibit movement of the contact layer with respect to the tissue layer of the user, and a second state adapted to enhance movement of the contact layer with respect to the tissue layer of the user. The engagement surface is adapted to transform from the first state to the second state upon application of a force greater than a threshold force. | 01-27-2011 |
William D. Joseph, Maplewood, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20090176443 | STRUCTURED FIXED ABRASIVE ARTICLES INCLUDING SURFACE TREATED NANO-CERIA FILLER, AND METHOD FOR MAKING AND USING THE SAME - Structured fixed abrasive articles including a multiplicity of three-dimensional abrasive composites fixed to the abrasive article, the abrasive composites further including a multiplicity of ceria abrasive particles having a volume mean diameter from 100 to 500 nanometers (nm) in a matrix material, the matrix material further including a polymeric binder and a multiplicity of surface treated ceria filler particles having a volume mean diameter less than 100 nm. Also provided are methods of making and using structured fixed abrasive articles according to the disclosure. | 07-09-2009 |
| 20100056024 | STRUCTURED ABRASIVE ARTICLE, METHOD OF MAKING THE SAME, AND USE IN WAFER PLANARIZATION - A structured abrasive article comprises an at least translucent film backing and an abrasive layer disposed on the backing. The abrasive layer comprises a plurality of shaped abrasive composites. The shaped abrasive composites comprise abrasive particles dispersed in a binder. The abrasive particles consist essentially of ceria particles having an average primary particle size of less than 100 nanometers. The binder comprises a polyether acid and a reaction product of components comprising a carboxylic(meth)acrylate and a poly(meth)acrylate, and, based on a total weight of the abrasive layer, the abrasive particles are present in an amount of at least 70 percent by weight. Methods of making and using the structured abrasive article are also disclosed. | 03-04-2010 |
| 20110143539 | POLISHING PAD WITH ENDPOINT WINDOW AND SYSTEMS AND METHODS USING THE SAME - A polishing pad including a path therethrough to transmit a signal for in situ monitoring of an endpoint in a polishing operation. In one embodiment, the polishing pad includes a polishing composition distribution layer on a first side of a guide plate and a support layer on an opposed second side of a guide plate. The guide plate retains a plurality of polishing elements that extend along a first direction substantially normal to a plane including the polishing pad and through the polishing composition distribution layer. The polishing pad includes an optical path along the first direction and through a thickness of the pad. | 06-16-2011 |
| 20110183583 | Polishing Pad with Floating Elements and Method of Making and Using the Same - The disclosure is directed to polishing pads with floating polishing elements bonded to a support layer, for example by thermal bonding, and to methods of making and using such pads in a polishing process. In one exemplary embodiment, the polishing pad includes a multiplicity of polishing elements, at least some of which may be porous, each polishing element affixed to a major surface of a support layer so as to restrict lateral movement of the polishing elements with respect to one or more of the other polishing elements, but remaining moveable in an axis substantially normal to the support layer. In certain embodiments, the polishing pad may additionally include a compliant layer affixed to the support layer opposite the polishing elements, and optionally, a polishing composition distribution layer. In some embodiments using porous polishing elements, the pores are distributed substantially at a polishing surface of the polishing elements. | 07-28-2011 |
William D. Joseph, Saint Paul, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20110159786 | Polishing Pad with Porous Elements and Method of Making and Using the Same - The disclosure is directed to polishing pads with porous polishing elements, and to methods of making and using such pads in a polishing process. In one exemplary embodiment, the polishing pad includes a multiplicity of polishing elements, at least some of which are porous, each polishing element affixed to a support layer so as to restrict lateral movement of the polishing elements with respect to one or more of the other polishing elements, but remaining moveable in an axis normal to a polishing surface of the polishing elements. In certain embodiments, the polishing pad may include a guide plate positioned to arrange and optionally affix the plurality of polishing elements on the support layer, and additionally, a polishing composition distribution layer. In some embodiments, the pores are distributed throughout substantially the entire porous polishing element. In other embodiments, the pores are distributed substantially at the polishing surface of the elements. | 06-30-2011 |