| Patent application number | Description | Published |
|---|
| 20090093596 | USE OF SILYLATED SULFONATE MONOMERS TO IMPROVE CONTACT LENS WETTABILITY - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain hydrophilic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerizable hydrophilic siloxanyl monomers. | 04-09-2009 |
| 20090117189 | Method for the Production of Polymerized Nanoparticles and Microparticles by Ternary Agent Concentration and Temperature Alteration Induced Immiscibility - Polymerized drug delivery devices are described. Additionally, methods are described for producing and for using polymerized particles for use as drug delivery devices. | 05-07-2009 |
| 20090122260 | Biomedical Devices - Biomedical devices are provided herein which are formed from a polymerization product of a monomeric mixture comprising (a) one or more esterified aminoalcohol monomers; and (b) one or more biomedical device-forming monomers. | 05-14-2009 |
| 20090142292 | Method For The Mitigation of Symptoms of Dry Eye - A method for the mitigation of symptoms of dry eye is disclosed. The method involves at least (a) incorporating one or more non-functionalized polymers having one or more hydrophilic moieties into an ophthalmic device that is a polymerization product of a comonomer mixture comprising: (i) a major amount of a non-silicone-containing hydrophilic monomer; and (ii) an end terminal functionalized surfactant; and (b) inserting the ophthalmic device in the eye of a patient. | 06-04-2009 |
| 20090142387 | Method For Inhibiting Attachment Of Microorganisms To Biomedical Devices - A method for inhibiting adhesion of bacteria to a surface of a biomedical device is disclosed. The method involves at least (a) incorporating one or more non-functionalized polymers having one or more hydrophilic moieties into an ophthalmic device that is a polymerization product of a comonomer mixture comprising: (i) a major amount of a non-silicone-containing hydrophilic monomer; and (ii) an end-terminal functionalized surfactant; and (b) inserting the ophthalmic device in the eye of a patient, wherein the at least one non-functionalized polymer migrates to the surface of the device in a sustained release manner to inhibit adhesion of bacteria to a surface of the biomedical device. Biomedical devices are also disclosed. | 06-04-2009 |
| 20090168013 | Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains - A method for reducing the modulus of polymer siloxane hydrogel compositions by employing monomeric polysiloxanes endcapped with trimethylsilyl to reduce the crosslinking density of the hydrogel. The synthesis consists of a single vessel acid catalyzed ring opening polymerization and may be employed to produce copolymers useful as hydrogel contact lens materials. | 07-02-2009 |
| 20090191256 | HIGH WATER CONTENT OPHTHALMIC DEVICES - An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an equilibrium water content of at least about 70 weight percent and further wherein the ophthalmic device has an evaporative dehydration barrier layer on the surface thereof. A method for the mitigation of evaporative corneal dehydration employing the high water content ophthalmic device is also disclosed. | 07-30-2009 |
| 20090192275 | MULTI-ARMED MACROMONOMERS - Multi-armed macromonomers containing multiple side chains attached to a siloxy-containing core terminated on each end with one or more first substantially linear polysiloxane radicals having a polymerizable ethylenically unsaturated-containing terminal group, wherein each side chain comprises a second substantially linear polysiloxane radical having a polymerizable ethylenically unsaturated-containing terminal group are disclosed. Biomedical devices such as contact lenses formed from the multi-armed macromonomers are also disclosed. | 07-30-2009 |
| 20100118261 | METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES - Novel polymers for biomedical use, especially rigid gas permeable contact lenses that are based on bulky side-chain siloxane cross linkers. The siloxanes, either alone, or as copolymers with bulky and non-bulky mono-functional polymerizable siloxanes, fluoro monomers, such as hexafluoroisopropyl methacrylate, and hydrophilic monomers, result in transparent, high oxygen permeable polymers possessing excellent lathing and milling characteristics. | 05-13-2010 |
| 20110015298 | PROCESS FOR MAKING CATIONIC HYDROPHILIC SILOXANYL MONOMERS - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymeric compositions comprise polymerized cationic hydrophilic siloxanyl monomers prepared by the process disclosed herein. | 01-20-2011 |
