| Patent application number | Description | Published |
|---|
| 20080296492 | METHODS AND APPARATUS FOR PERFORMING CHROMATOGRAPHY AND MASS SPECTROSCOPY WITH SUPERCRITICAL FLUID SAMPLES - Embodiments of the present invention are directed to devices and methods for receiving NSC Fluids having at least one analyte from a chromatograph and directing analyte ions into the vacuum regions of a mass spectrometer. The device has a housing having at least one wall defining a chamber, sample inlet, an ionization media inlet and an outlet. The sample inlet has a position in communication with a chromatograph receiving a NSC Fluid. The sample inlet receives the NSC Fluid and directs the NSC Fluid into the chamber to form a sample jet of NSC Fluid. The ionization media inlet is placed in fluid communication with a source of ionization media and directs the ionization media into the chamber and the sample jet to create analyte ions. The analyte ions are received in the mass spectrometer vacuum region orifice. | 12-04-2008 |
| 20090027671 | EVAPORATIVE LIGHT SCATTERING DETECTOR - Embodiments of the present invention are directed to evaporation light scattering detectors having an evaporative chamber having a wall that is in good thermal contact with a heat sink. The heat has a high thermal mass such that a change in temperature of the wall during an analysis is minimized. | 01-29-2009 |
| 20090122315 | EVAPORATIVE LIGHT SCATTERING DEVICE AND METHODS OF USE THEREOF - Apparatus for the detection of analytes in a fluid, for example the eluant from a liquid chromatography is described. Solvent is evaporated from the eluant to produce a stream of particles when analyte is present in the fluid. The resultant stream of particles is passed through one or more beams of radiation, typically visible light, and radiation scattered by the particles is detected at least at a first angle to a beam of radiation and at a second, different, angle to a radiation beam to produce a signal indicative of the presence of the analyte. | 05-14-2009 |
| 20090159751 | DEVICES AND METHODS FOR PREVENTING ICE BUILD-UP AND ARTICLES OF MANUFACTURE THAT ARE RESISTANT TO ICE BUILD-UP - Embodiments of the present invention feature heat exchange surfaces having a layer or coating having a lower surface tension than water, to repel water and prevent the formation of condensate on said surface. | 06-25-2009 |
| 20090218487 | MASS-SPECTROMETER INTERFACE HOUSING - An apparatus for performing chemical analyses includes a mass spectrometry module and an interface module that processes sample materials for delivery to the mass spectrometry module. The interface module includes a vessel having an opening to access a vessel chamber, a door to block the opening, a sealing member disposed between the door and the vessel, and an interlock. The interlock is actuated by the sealing member if the door is in the closed position and the sealing member is properly disposed between the door and the vessel to seal the vessel. The sealing member alternatively includes an indicator portion that is visible to an operator if the door is in the closed position and the sealing member is properly disposed. | 09-03-2009 |
| 20100133431 | Device, Apparatus And Methods For Mass Spectrometry - The invention comprises apparatus for use with atmospheric pressure ionization sources in which an aerosol is formed from a solution of a sample. The aerosol is received in a hollow member and discharged outside the chamber of the ionization source in order to reduce contamination of the ionization source itself by involatile material in the solution and by previously analysed samples. The hollow member is easily removable from the ionization source to facilitate cleaning and replacement. Ionization sources, mass spectrometers, and ion mobility spectrometers comprising the apparatus are also described. | 06-03-2010 |
| 20100148057 | Device And Method For Analyzing A Sample - Embodiments of the invention relate to a device for analysing a sample surface Comprising an outlet and a frame. The outlet is for forming a jet of gas, the jet forming a sampling region for receiving one or more sample surfaces, and the frame holding the outlet and being adapted to receive a detector means. The detector means has an inlet. In use, the jet produces desorbed sample from sample surfaces received in the sample area. At least a portion of the desorbed sample is ionized to produce one or more sample ions. The frame holds the outlet with respect to the sample ions and produce a signal indicative of the composition of the sample ions. | 06-17-2010 |
| 20100320374 | DEVICES AND METHODS FOR PERFORMING MASS ANALYSIS - Embodiments of the present invention feature devices and methods for performing mass analysis. One embodiment of the device comprises an inlet housing for mounting on the first wall between the area of low pressure and the area of high pressure. The inlet housing has passages and restrictions which can be adjusted with respect to a sample plume or changed by substituting alternative inlet housings. | 12-23-2010 |
| 20110107822 | Interfacing With A Digital Microfluidic Device - Described are techniques for use in connection with analyzing a droplet. One or more droplets of a sample are formed on a surface of a digital microfluidic device. The droplets are manipulated to perform processing using said one or more droplets generating one or more resulting droplets. The one or more resulting droplets may be transferred from the microfluidic device to another device for analysis. The one or more droplets may also be provided to the digital microfluidic device from yet another device or analysis instrument. | 05-12-2011 |
| 20110121093 | Apparatus And Methods For Making Analyte Particles - A device for making particulate analyte molecules comprising a nebulizer producing a plume of liquid droplets, a vessel having a chamber to receive the plume in which the chamber has a nebulization section, a desolvation section. The nebulization section is cooled to form a condensed waste from a portion of said plume. The desolvation section is heated to form solvent gas molecules and particulate analyte molecules. | 05-26-2011 |
| 20110134428 | Evaporative Light Scattering Detector - Described is a detector for receiving the eluent from a liquid- or supercritical-fluid chromatograph in which a signal indicative of the presence of an analyte in the eluent is generated by the scattering of light by desolvated particles of the analyte. The detector includes a nebulizer for generating an aerosol from the eluent in a chamber that has a wall in thermal communication with a heat sink. Changes in the temperature of the wall during an analysis of the eluent are reduced by the transfer of heat to the first heat sink. | 06-09-2011 |
