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José Alberto
José Alberto Crottogini, Buenos Aires AR
| Patent application number | Description | Published |
|---|---|---|
| 20090275645 | METHOD TO INDUCE NEOVASCULAR FORMATION AND TISSUE REGENERATION - The present invention relates, e.g., to a method for inducing arteriogenesis, lymphangiogenesis, vasculogenesis, or cardiomyogenesis, and/or for inducing mitosis or proliferation of a smooth muscle cell, a skeletal muscle cell, or a cardiomyocyte, comprising administering to a cell or tissue in need thereof a dose of a polynucleotide that encodes a vascular endothelial growth factor (VEGF), or that encodes a polypeptide comprising an active site of the VEGF. The coding sequence is operably linked to an expression control sequence; and the dose is sufficient to induce arteriogenesis, lymphangiogenesis, vasculogenesis, or cardiomyogenesis, and/or to induce mitosis or proliferation of a smooth muscle cell, a skeletal muscle cell, or a cardiomyocyte. In preferred embodiments of the invention, the method is a method of tissue regeneration, particularly of cardiomyogenesis; and the polynucleotide (or a polypeptide encoded by such a polynucleotide) is administered into the myocardium. | 11-05-2009 |
José Alberto Crottogini, Buenos Aires AR
| Patent application number | Description | Published |
|---|---|---|
| 20090275645 | METHOD TO INDUCE NEOVASCULAR FORMATION AND TISSUE REGENERATION - The present invention relates, e.g., to a method for inducing arteriogenesis, lymphangiogenesis, vasculogenesis, or cardiomyogenesis, and/or for inducing mitosis or proliferation of a smooth muscle cell, a skeletal muscle cell, or a cardiomyocyte, comprising administering to a cell or tissue in need thereof a dose of a polynucleotide that encodes a vascular endothelial growth factor (VEGF), or that encodes a polypeptide comprising an active site of the VEGF. The coding sequence is operably linked to an expression control sequence; and the dose is sufficient to induce arteriogenesis, lymphangiogenesis, vasculogenesis, or cardiomyogenesis, and/or to induce mitosis or proliferation of a smooth muscle cell, a skeletal muscle cell, or a cardiomyocyte. In preferred embodiments of the invention, the method is a method of tissue regeneration, particularly of cardiomyogenesis; and the polynucleotide (or a polypeptide encoded by such a polynucleotide) is administered into the myocardium. | 11-05-2009 |
José Alberto Ginebra Giudicelli, Santo Domingo DO
| Patent application number | Description | Published |
|---|---|---|
| 20110061275 | SYSTEM AND METHOD OF ADVERTISING AND ADVERTISEMENT DISPLAY DEVICE - A system and method of presenting “one-to-one” advertising within a parking spot and a corresponding parking block display device is presented. The system and method comprise an illuminated advertisement message displayed and directed toward an associated vehicle parking spot, wherein the message comprises indicia corresponding to and tailored toward an intended recipient expected to park a vehicle in the vehicle parking spot. Moreover, the display device may be in the form of a parking block or wheel stop and, in at least one embodiment, includes a housing structured to define an at least partially hollow interior portion. The display device may further comprise an illumination assembly structured and positioned so as to direct a path of light to the exterior of the housing at least partially through one or more display members bearing the message or advertisement. | 03-17-2011 |
José Alberto Ginebra Giudicelli, Santo Domingo DO
| Patent application number | Description | Published |
|---|---|---|
| 20110061275 | SYSTEM AND METHOD OF ADVERTISING AND ADVERTISEMENT DISPLAY DEVICE - A system and method of presenting “one-to-one” advertising within a parking spot and a corresponding parking block display device is presented. The system and method comprise an illuminated advertisement message displayed and directed toward an associated vehicle parking spot, wherein the message comprises indicia corresponding to and tailored toward an intended recipient expected to park a vehicle in the vehicle parking spot. Moreover, the display device may be in the form of a parking block or wheel stop and, in at least one embodiment, includes a housing structured to define an at least partially hollow interior portion. The display device may further comprise an illumination assembly structured and positioned so as to direct a path of light to the exterior of the housing at least partially through one or more display members bearing the message or advertisement. | 03-17-2011 |
José Alberto Rodríguez González, Coahuila MX
| Patent application number | Description | Published |
|---|---|---|
| 20120098163 | CONTINUOUS PROCESS ASSISTED BY ULTRASOUND OF VARIABLE FREQUENCY AND AMPLITUDE FOR THE PREPARATION OF NANOCOMPOSITES BASED ON POLYMERS AND NANOPARTICLES - The invention relates to a continuous mixing/extrusion method, assisted by ultrasound waves with a variable amplitude and frequency, for the preparation of nanocompounds based on polymers, preferably thermoplastics and nanoparticles, at a concentration of up to 60 wt.-% of the total weight of the polymer/nanoparticle mixture. According to the invention, the polymer/nanoparticle mixture is subjected in the molten state to a discrete and continuous sweep with a variable amplitude and frequency, of between 15 kHz and 50 kHz. | 04-26-2012 |