| Patent application number | Description | Published |
|---|
| 20080306257 | Syntheses and Preparations of Narwedine and Related Novel Compounds - The present invention relates to a process for preparing racemic narwedine (which can be can be kinetically resolved) to yield (−)-narwedine and which is the biogenic precursor of (−)-galanthamine) and the use thereof as a starting material for producing (−)-galanthamine. The invention further includes processes for preparing (−)-galanthamine and (−)-galanthamine hydrobromide, as well as related novel compounds. | 12-11-2008 |
| 20080312455 | Method For Determining Enantiomeric Purity Of Darifenacin And Intermediates - The present invention relates to a method for differentiating and quantifying the enantiomers, thereby determining the enantiomeric purity, of darifenacin and its intermediate compounds and salts thereof. In addition, the invention relates to a method for differentiating and quantifying the enantiomers, thereby determining the enantiomeric purity of compounds of formula (I): | 12-18-2008 |
| 20090043126 | Process and Methods for the Preparation of Gabapentin and Its Intermediates - The invention provides a process for preparing gabapentin and its intermediates. The process generally involves treating gabapentin lactam with an aqueous solution of hydrobromic acid to yield gabapentin hydrobromide salt as an intermediate, which can be isolated by filtration. The gabapentin hydrobromide salt can then be hydrolyzed with a base, such as an organic amine, to yield gabapentin that can be isolated by filtration. | 02-12-2009 |
| 20090076262 | PROCESS FOR PREPARING QUETIAPINE AND QUETIAPINE FUMARATE - The invention comprises a process for preparing quetiapine and/or its salts, including, quetiapine fumarate. The process generally comprises reacting dibenzothiazepinone (dibenzo[bf][1,4]thiazepin-11(10H)-one) with phosphorous oxychloride in the presence of triethylamine in an aromatic organic solvent such as toluene or, preferably, xylene at reflux temperature to obtain an aromatic hydrocarbon solution of 11-chloro-dibenzo[bf][1,4]thiazepine. Thereafter, the 11-chloro-dibenzo[bf][1,4]thiazepine is reacted with 2-(2-piperazin-1-ylethoxy)-ethanol to yield, following several processing steps, quetiapine. Compound I can then be further reacted with fumaric acid at elevated temperature to yield quetiapine fumarate. The resulting quetiapine fumarate obtained is suitable for use in pharmaceutical preparations. | 03-19-2009 |
| 20090247642 | SYNTHESIS AND PREPARATIONS OF METOPROLOL AND ITS SALTS - The invention relates to an improved process for preparing metoprolol and its salts. | 10-01-2009 |
| 20090292141 | NEW METHOD FOR OBTAINING AN AMINOINDAN MESYLATE DERIVATIVE - The invention relates to processes for preparing rasagiline mesylate that avoid the use of alcohol solvents, thereby producing rasagiline mesylate free of any alkyl mesylates, including isopropyl mesylate. The invention further relates to processes for purifying rasagiline mesylate to obtain a product free of alkyl mesylates, and to the thus obtained rasagiline mesylate. | 11-26-2009 |
| 20100280272 | METHOD FOR OBTAINING AN AMINOINDAN MESYLATE DERIVATIVE - The invention relates to processes for preparing rasagiline mesylate that avoid the use of alcohol solvents, thereby producing rasagiline mesylate free of any alkyl mesylates, including isopropyl mesylate. The invention further relates to processes for purifying rasagiline mesylate to obtain a product free of alkyl mesylates, and to the thus obtained rasagiline mesylate. | 11-04-2010 |
| 20110034731 | Solid Forms Of An N-(Phenylmethyl)Propanamide Derivative And Processes Of Preparation - The invention relates to solid forms of the anti-epileptic agent lacosamide (I). The invention also relates to mixtures of solid forms of lacosamide. The invention further relates to mixtures of lacosamide enantiomers crystallized in a conglomerate Form and the use thereof in providing enantiomerically enriched lacosamide, preferably lacosamide enriched with the (R)-enantiomer of lacosamide. | 02-10-2011 |
