Patent application number | Description | Published |
20100035303 | Method of Amplifying Target Nucleic Acid Sequence By Multiple Displacement Amplification Including Thermal Cycling - A method of amplifying a target nucleic acid sequence includes multiple displacement amplification and thermal cycling. According to the method, the target nucleic acid sequence may be effectively amplified. | 02-11-2010 |
20100056397 | Method of Producing Microarray Having Immobilized Double-Stranded Nucleic Acid Probe Including Double-Stranded Region and Single-Stranded Region - A method of producing a microarray having an immobilized double-stranded nucleic acid probe including a double-stranded region and a single-stranded region includes immobilizing nucleic acids by synthesizing nucleic acids by using photolithography and hybridizing nucleic acids. A microarray with a high spot density and with immobilized long probes may be prepared. | 03-04-2010 |
20110159484 | APPARATUS AND METHOD OF AUTHENTICATING PRODUCT USING POLYNUCLEOTIDES - A method of authenticating a product includes; hybridizing a target polynucleotide which is associated with the product and which includes a first target region and a second target region adjacent to the first target region with a probe polynucleotide that comprises a first segment having a nucleotide sequence completely complementary to the first target region and a second segment having a nucleotide sequence completely complementary to the second target region, ligating one end of the first segment of the probe polynucleotide to one end of the second segment of the probe polynucleotide, amplifying the probe polynucleotide and detecting the amplified polynucleotide. | 06-30-2011 |
20110214991 | MICROFLUIDIC DEVICE AND METHOD OF DETERMINING NUCLEOTIDE SEQUENCE OF TARGET NUCLEIC ACID USING THE SAME - A microfluidic device includes at least one first channel and at least one second channel or chamber which is connected to the first channel via a nanopore in a fluid communication manner, and a method of determining a nucleotide sequence of a target nucleic acid by using the same. Accordingly, the nucleotide sequence of the target nucleic acid may be efficiently determined. | 09-08-2011 |
20120064510 | KIT INCLUDING TARGET SEQUENCE-BINDING PROTEIN AND METHOD OF DETECTING TARGET NUCLEIC ACID BY USING THE KIT - A kit including a target sequence-binding protein and a method of detecting a target nucleic acid by using the kit that may ensure efficient detection of the target nucleic acid in a biological sample are disclosed. | 03-15-2012 |
20120164754 | KIT AND METHOD OF DETERMINING NUCLEOTIDE SEQUENCE OF TARGET NUCLEIC ACID - A kit for determining a nucleotide sequence of a target nucleic acid, and a method of determining a nucleotide sequence of a target nucleic acid using the kit are disclosed. | 06-28-2012 |
20120225457 | NANOPARTICLE-NUCLEIC ACID COMPLEX AND METHOD OF LINEARIZING TARGET NUCLEIC ACID - A nanoparticle-nucleic acid complex and a method of linearizing a target nucleic acid by using the nanoparticle-nucleic acid complex are disclosed. By using the nanoparticle-nucleic acid complex and the method, nucleotide sequence analysis and mapping of a target nucleic acid may be efficiently performed. | 09-06-2012 |
20130122577 | KIT INCLUDING SEQUENCE SPECIFIC BINDING PROTEIN AND METHOD AND DEVICE FOR DETERMINING NUCLEOTIDE SEQUENCE OF TARGET NUCLEIC ACID - Provided are kits for determining a nucleotide sequence of a target nucleic acid, the kit including at least one sequence specific binding protein and a detectable tag. In accordance with a kit for determining a nucleotide sequence of a target nucleic acid according to one exemplary embodiment and a method and device for determining a nucleotide sequence of a target nucleic acid, the nucleotide sequence of the target nucleic acid may be more efficiently determined. | 05-16-2013 |
20130157259 | METHOD OF AMPLIFYING DNA FROM RNA IN SAMPLE AND USE THEREOF - Provided are methods of efficiently amplifying DNA from RNA in sample, methods of efficiently estimating an amount of RNA in a sample, and compositions for efficiently amplifying DNA from RNA in a sample. | 06-20-2013 |
20130157269 | METHOD OF DETERMINING A RATIO OF RNA SPECIES IN A SAMPLE - A method of amplifying DNA from RNA in a sample by using circular RNA is provided. | 06-20-2013 |
20140057322 | METHOD OF AMPLIFYING DNA FROM RNA IN A SAMPLE - A method of amplifying RNA in a sample and a method of amplifying a pool of RNA is provided. Gene loss and amplification bias may be reduced using the methods. Also, directionality may be preserved in the amplified RNA. The methods may be applied in sequence analysis as well as in general molecular diagnostic areas. | 02-27-2014 |
20140147840 | METHOD OF LABELING A TARGET NUCLEIC ACID - Methods of labeling and detecting a target nucleic acid by incubating a target nucleic acid with a terminal transferase to extend a terminus of the target nucleic acid and provide an extended region; hybridizing the extended region of the target nucleic acid with a template polynucleotide having a nucleotide sequence complementary to the extended region to obtain a hybridization product; and incubating the hybridization product with a nucleic acid polymerase and either a deoxynucleotide triphosphate (dNTP) having a detectable label or nucleotide triphosphate (NTP) having a detectable label to further extend the extended target nucleic acid. | 05-29-2014 |
20140162276 | METHOD OF AMPLIFYING TARGET NUCLEIC ACID, METHOD OF ANALYZING TARGET NUCLEIC ACID, KIT FOR AMPLIFYING TARGET NUCLEIC ACID, AND COMPOSITION FOR AMPLIFYING TARGET NUCLEIC ACID - Provided are methods of efficiently amplifying or analyzing a target nucleic acid and a kit and a composition to efficiently amplify a target nucleic acid. | 06-12-2014 |
20140308709 | POLYNUCLEOTIDE AND USE THEREOF - Provided is a polynucleotide including, from the 3′ terminus of the polynucleotide to the 5′ terminus of the polynucleotide, a first region including a nucleotide sequence complementary to a nucleotide sequence of a portion of a target nucleic acid; a second region including a nucleotide sequence identical to a nucleotide sequence of a portion of the target nucleic acid; and a third region including a nucleotide sequence that self-hybridizes to form a stem-loop structure, and compositions, kits, and methods related thereto. | 10-16-2014 |
20150072882 | METHOD OF DETECTING NUCLEIC ACIDS - A method of detecting a target nucleic acid, and a polynucleotide and a composition for detecting a target nucleic acid. | 03-12-2015 |
20150080241 | POLYNUCLEOTIDE AND USE THEREOF - A polynucleotide comprising a first region the 5′ end of which is complementary to a portion of a target nucleic acid, a cleavable second region, a third region having a stem-loop structure, and a fourth region complementary to the 3′ end of the first region, and use of the polynucleotide, as well as a composition comprising two such polynucleotides each of which hybridize different strands of a double-stranded target nucleic acid, and methods and kits using the same for amplifying targets. | 03-19-2015 |
Patent application number | Description | Published |
20090057599 | ELASTIC VALVE AND MICROFLUIDIC DEVICE INCLUDING THE SAME - An elastic valve and a microfluidic device including the same are provided. The elastic valve includes a channel dented by external pressure so as to be elastically restituted; and a plurality of channel closing protrusions, which comprise elastomer as a material, which are protruded from at least one inner side surface of the channel toward an opposite inner side surface, and which are separated from each other so as not to interrupt a flow of fluids, wherein, when external pressure is applied in order to dent the channel, the plurality of channel closing protrusions are deformed so as to be elastically restituted, thereby closing the channel. | 03-05-2009 |
20090074623 | MICROFLUIDIC DEVICE - Provided is a microfluidic device including a substrate; a chamber formed by a groove in a bottom surface of the substrate, whereby a fluid can be accommodated in the chamber; and an adhesive tape adhered to the bottom surface of the substrate, wherein the adhesive tape includes a polymer film and a silicone adhesive agent coated on the polymer film. | 03-19-2009 |
20090098612 | METHOD OF AMPLIFYING A TARGET NUCLEIC ACID BY ROLLING CIRCLE AMPLIFICATION - Provided is kit for and a method of amplifying a nucleic acid using rolling cyclic amplification (RCA), including amplifying a nucleic acid together with formation of a single-strand circular DNA template using RCA by reacting a reaction solution including: (a) two hairpin oligos, (b) a target nucleic acid, (c) a DNA ligase,(d) an endonuclease, (e) a DNA polymerase, and (f) a primer. | 04-16-2009 |
20090150085 | METHOD OF DETERMINING INITIAL CONCENTRATION OF NUCLEIC ACID IN SAMPLE USING REAL-TIME AMPLIFICATION DATA - Disclosed is a method of determining an initial concentration of a target nucleic acid within a sample using real-time nucleic acid amplification data. Amplification efficiencies of the target nucleic acid with respect to amplification time are obtained from signals of amplified products, and an amplification efficiency function with respect to amplification time is formulated employing the amplification efficiencies. | 06-11-2009 |
20090239770 | DETECTION OLIGOMER AND METHOD FOR CONTROLLING QUALITY OF BIOCHIP USING DETECTION OLIGOMER - A detection oligomer and method for controlling the quality of a biochip using the detection oligomer are provided. The detection oligomer includes a template having a first and second end and having a sequence that is complementary to a specific sequence of an oligomer, and a hairpin connected to the first end of the template. | 09-24-2009 |
20110269193 | METHOD OF AMPLIFYING A TARGET NUCLEIC ACID BY ROLLING CIRCLE AMPLIFICATION - Provided is a method of amplifying a nucleic acid using rolling cyclic amplification (RCA), including amplifying a nucleic acid together with formation of a single-strand circular DNA template using RCA by reacting a reaction solution including: (a) two hairpin oligos, (b) a target nucleic acid, (c) a DNA ligase, (d) an endonuclease, (e) a DNA polymerase, and (f) a primer. | 11-03-2011 |