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Johnstone, CA

Eric Johnstone, Montreal CA

Patent application numberDescriptionPublished
20080312549Method and Apparatus for Determining Spasticity - There is provided a system and a method for quantitative measurement of spasticity in a patient. It has been found that stretch reflex measurements, that are quantitatively indicative of spasticity, can be obtained by recording an EMG signal while the limb is being moved at a variety of angular velocities. The method advantageously allows the clinician to perform the test at the bedside by eliminating the need for cumbersome mechanical components for moving the limb while providing quantitative measurements.12-18-2008
20090149334METHODS AND APPARATUS FOR DETECTING LIQUID INSIDE INDIVIDUAL CHANNELS IN A MULTI-CHANNEL PLATE - There is provided a method of measuring properties of a liquid contained in individual wells inside a multi-well array, the method comprising steps of providing capacitor electrodes in the multi-well array, the electrodes adapted to detect a capacitance value of each one of the individual wells without interference of neighboring wells, measuring a capacitance inside each one of the individual wells, and using the capacitance measurements to calculate at least one property of the liquid contained in each one of the individual wells. There is further provided an apparatus for measuring properties of a liquid contained in individual wells inside a multi-well array, and a method of controlling quality of liquid handling task that is repeated across a set of individual wells inside a multi-well array.06-11-2009

Robert Johnstone, Edmonton CA

Patent application numberDescriptionPublished
20110192600PRECISION LOW FLOW RATE FLUID DELIVERY SYSTEM AND METHODS FOR CONTROLLING SAME - A method is provided for controllably delivering an additive fluid into a host fluid in a target system at a desired volumetric flow rate. The method comprises: providing a binary supply injector connected in an additive fluid delivery system between a pressurized supply of the additive fluid and the target system. The binary supply injector is controllable between an ON state which permits flow of the additive fluid therethrough and an OFF state which prevents flow of the additive fluid therethrough. The method involves iteratively repeating: estimating a volumetric flow rate of the additive fluid between the pressurized supply and the target system; and if the estimated volumetric flow rate of the additive fluid is greater than the desired volumetric flow rate, controlling the supply injector to its OFF state; or if the estimated volumetric flow rate of the additive fluid is less than the desired volumetric flow rate, controlling the supply injector to its ON state. Additive fluid delivery systems are also provided.08-11-2011

Sharon Johnstone, Vancouver CA

Patent application numberDescriptionPublished
20090074848COMBINATION FORMULATIONS OF CYTIDINE ANALOGS AND PLATINUM AGENTS - Compositions which comprise delivery vehicles having stably associated therewith a cytidine analog and a platinum agent are useful in achieving enhanced therapeutic effects when combinations of these drugs are administered.03-19-2009
20090148506LIPOSOMAL FORMULATIONS COMPRISING SECONDARY AND TERTIARY AMINES AND METHODS FOR PREPARING THEREOF - Provided herein are liposomal compositions comprising a therapeutic agent having a protonatable amino group and a secondary or tertiary amine, and methods for encapsulating such therapeutic agents. In one aspect, the present invention relates to liposomal formulations comprising irinotecan in a triethanolamine solution, and optionally comprising copper gluconate, and methods for preparing the same.06-11-2009

Patent applications by Sharon Johnstone, Vancouver CA

Shawn Johnstone, Montreal CA

Patent application numberDescriptionPublished
20090062251Novel Compounds 002 - Compounds of Formulae I, or pharmaceutically acceptable salts thereof:03-05-2009
20100286202New Compounds - The present invention relates to new compounds11-11-2010
20110160180Cannabinoid Receptor Ligands - Compounds of Formulae (I), or pharmaceutically acceptable salts thereof: wherein R06-30-2011

Patent applications by Shawn Johnstone, Montreal CA

Shawn Johnstone, St. Laurent CA

Patent application numberDescriptionPublished
20080221188New Benzimidazole Derivatives - Provided herein are compounds in accord with Formula I:09-11-2008
20110137045BENZIMIDAZOLE DERIVATIVES - Provided herein are compounds in accord with Formula I:06-09-2011

Patent applications by Shawn Johnstone, St. Laurent CA

Stephen Johnstone, Mississauga CA

Patent application numberDescriptionPublished
20080226693Apparatus and Method for Making a Polymeric Structure - The apparatus and method for preparing a polymeric structure from which a number of medical devices may be constructed is described. The structures are preferably formed from bioabsorbable materials using low temperature fabrication processes, whereby drugs or other bio-active agents are incorporated into or onto the device and degradation of the drugs or other agents during processing is minimized. The method includes preparing a solution of at least one bioabsorbable polymer and a solvent. The solution is then deposited onto a stage and converted into a structure. The solvent is evaporated from the structure. The dried solution forms a structure that is removed from the stage and further dried before being stored in an inert environment. Thereafter, a medical device such as a stent may be constructed from the structure.09-18-2008