| Patent application number | Description | Published |
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| 20080260775 | New Live Virus Vaccines - The present invention provides novel self-replicating and self-propagating chimeric viral vectors and chimeric virus particles comprising a modified genome of a carrier RNA virus packaged within structural proteins of a second virus. Also provided are pharmaceutical formulations comprising the chimeric viral vectors and virus particles and methods of inducing an immune response by administration of the same to a subject. | 10-23-2008 |
| 20080279891 | Viral Adjuvants - The present invention provides viral adjuvants for enhancing an immune response to an immunogen. In particular embodiments, the viral adjuvant is an alphavirus adjuvant or a Venezuelan Equine Encephalitis viral adjuvant. Also provided are compositions comprising the viral adjuvant and an immunogen, and pharmaceutical formulations comprising the viral adjuvant or compositions of the invention in a pharmaceutically acceptable carrier. Further provided are methods of producing an immune response against an immunogen in a subject comprising administering the immunogen and a viral adjuvant of the invention to the subject. | 11-13-2008 |
| 20090162395 | VACCINE FOR RSV AND MPV - The present invention is directed to alphavirus vectored vaccine contructs encoding paramyxovirus proteins that find use in the prevention of respiratory syncytial virus or human metapneumovirus infections. In particular, these vaccines induce cellular and humoral immune responses that inhibit RSV. Also disclosed are improved methods for producing alphavirus vectored paramyxovirus vaccines. | 06-25-2009 |
| 20110064772 | VIRAL ADJUVANTS - The present invention provides viral adjuvants for enhancing an immune response to an immunogen. In particular embodiments, the viral adjuvant is an alphavirus adjuvant or a Venezuelan Equine Encephalitis viral adjuvant. Also provided are compositions comprising the viral adjuvant and an immunogen, and pharmaceutical formulations comprising the viral adjuvant or compositions of the invention in a pharmaceutically acceptable carrier. Further provided are methods of producing an immune response against an immunogen in a subject comprising administering the immunogen and a viral adjuvant of the invention to the subject. | 03-17-2011 |
| Patent application number | Description | Published |
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| 20080259930 | Message Flow Model of Interactions Between Distributed Services - A computer-implementable method, system and computer-usable medium for defining a message flow model of interactions between distributed services are presented. In a preferred embodiment, the method includes the steps of: capturing unidirectional network-level message traffic between services in a network; identifying service end-points from information obtained from the uni-directional network-level message traffic; identifying message interactions of captured uni-directional network-level message traffic between identified service end-points; applying formal and informal interface definitions to the captured unidirectional network-level message traffic; categorizing each captured unidirectional network-level message traffic as being a public network-level message traffic or a private network-level message traffic; filtering the captured uni-directional network-level message traffic to filter out any formally defined captured uni-directional network-level message traffic; correlating message exchanges for filtered uni-directional network-level message traffic to identify a relationship between correlated message exchanges; and analyzing the network according to identified relationships between correlated message exchanges. | 10-23-2008 |
| 20080313597 | System and Method for Describing Method Process Using Guided Architectural Decisions - A method author uses a method generator to create a customized project-specific method that includes first class decision elements. The decision elements are included in a meta model for a process framework, and describe actual decisions for a user to resolve. Once created, a method advisor uses the project-specific method to guide a user through architectural decisions by refining the project-specific method's process flow based upon the user's decisions. The refining includes removing activity elements and decision elements from the process flow that are not reachable by a path corresponding to the user's choice selection. The method advisor also stores the user's choice selections, along with considerations, conditions, and consequences, for the use to view at a later date. | 12-18-2008 |
| 20090105941 | AUTOMATIC DESTINATION DETERMINATION FOR MULTIPLE TRAVELERS DEPARTING FROM MULTIPLE SOURCE LOCATIONS BASED ON USER SPECIFIED CRITERIA - The present invention discloses a software implemented solution for automatically determining a travel destination. The method can identify a set of source locations, each source location representing a starting location of a traveler. Criteria for a destination to which each of the travelers is to travel can then be identified. At least one destination can be determined based upon the identified criteria. Directions for traveling from each of the source locations to the determined destination can be constructed. | 04-23-2009 |
| 20090138249 | DEFINING OPERATIONAL ELEMENTS IN A BUSINESS PROCESS MODEL - Embodiments of the invention provide a method, system and computer program product for rendering a process model through a configuration of a unitary operational element in the process modeling data processing system. The method can include parsing semantic elements in a semantic process model and identifying different types for the semantic elements as well as different connections amongst the semantic elements in the semantic process model. The method further can include initializing a visual model to include instances of a unitary operational element, and for each of the semantic elements, an instance of a unitary operational element can be configured in the visual model with zero or more inbound and outbound connections according to an identified type and connecting paths between respective outbound and inbound connections of different instances of the unitary operational element based upon the different connections amongst the semantic elements. Finally, the visual model can be displayed. | 05-28-2009 |
| 20090187573 | REPRESENTING MODELS IN SYSTEMS DEVELOPMENT LIFECYCLE (SDLC) TOOLS USING A NETWORK OF INTERNET RESOURCES - In the present solution, as set of SDLC resources can be established, where each is separately addressable through a unique URL and is able to be managed through a simple set of operations. For example, a set of RESTful operations (GET, POST, PUT, and DELETE) can be used for the operations. Database management technologies can be leveraged for storing and indexing resources, but the underlying database schema for the solution can operate on a resource level, which results in the resources being stored as-is. Thus, storage (even when database based) of resources for the solution can be considered an Internet server exposing a space of URL addressable objects. Because the solution leverages Internet technologies and standards, it is scalable, standards based, extensible, and traceable. | 07-23-2009 |
| 20110125904 | INDEXING HETEROGENOUS RESOURCES - Resources are typically stored in homogenous data structures by shredding resource data into database tables destroying a native format of the resources. Typical approaches to indexing the resources rely on users indicating properties that should be indexed, using full text searches to create resource index documents, and other such labor and computation intensive processes. Functionality can be implemented to dynamically generate the resource index documents based on resource properties with minimal user input. The resource index documents can be in a_common format to facilitate access to resources stored in heterogeneous native resource formats. | 05-26-2011 |
