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Johnson, NJ
Brian K. Johnson, Princeton, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090087492 | Processes and Apparatuses for the Production of Crystalline Organic Microparticle Compositions by Micro-Milling and Crystallization on Micro-Seed and Their Use - The present invention relates to a process, for the production of crystalline particles of an active organic compound The process includes the steps of generating a micro-seed by a wet-milling process and subjecting the micro-seed to a crystallization process. The resulting crystalline particles have a mean particle size of less than about 100 μm. The present invention also provides for a pharmaceutical composition which includes the crystalline particles produced by the method described herein and a pharmaceutically acceptable carrier. | 04-02-2009 |
Bruce C. Johnson, Whiting, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110152604 | INTRAVAGINAL INCONTINENCE DEVICE - An intravaginal urinary incontinence device has an insertion end and an opposed withdrawal end. The device has a resilient frame including a working portion disposed proximate the withdrawal end and an anchoring portion disposed proximate the insertion end. The working portion has a resilient structure having a plurality of connected elongate elements arranged and configured to define opposed working surfaces for providing support to an associated urinary system. The anchoring portion extends beyond the working portion and has a plurality of connected elongate elements arranged and configured to expand laterally within a user's vagina. The elongate elements are formed of a high modulus polymer having an elongation at yield of at least 3% and an elastic modulus of at least 2 Gpa. | 06-23-2011 |
| 20110152605 | INTRAVAGINAL INCONTINENCE DEVICE - An intravaginal urinary incontinence device has an insertion end and an opposed withdrawal end. The device has a resilient frame including a working portion disposed proximate the withdrawal end and an anchoring portion disposed proximate the insertion end. The working portion has a resilient structure having a plurality of connected elongate elements for providing support to an associated urinary system. The anchoring portion has a plurality of connected elongate elements arranged to expand laterally within a user's vagina. The elongate elements are formed of a high modulus polymer having an elastic modulus of at least 2 or 3 GPa. Additionally, the polymer may have an Initial Stress @ 3% Strain of at least about 30 MPa, an elongation at yield of at least 3%, a Stress Ratio of at least about 0.5, and/or an Aged Stress (t=50 hrs @ 40° C.) @ 3% Strain is greater than about 35 MPa. | 06-23-2011 |
Burnitta B. Johnson, East Rutherford, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080317907 | Method and apparatus for applying aqueous coating to cooked foods - A cooked snack food or cooked edible core material, such as roasted nuts, or baked snack chips, while still hot from the cooking step, is tumbled and sprayed with an aqueous solution of a water-soluble, film-forming coating component, such as a maltodextrin. The tumbling and spraying is performed immediately after cooking so that latent heat from the cooked edible core material, reduces the moisture content of the applied aqueous solution to form a dry, thin film coating of the coating component on the edible core material. The need for a separate, subsequent drying step or forced air drying equipment to reduce the moisture content is eliminated by evaporative cooling of the hot cooked snacks and flashing of the applied aqueous coating solution. The dry, coated cooked snack may be cooled to obtain a snack food having a thin, uniform coating which enhances appearance, texture, taste and shelf life. | 12-25-2008 |
Carl Johnson, Cinnaminson, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100005014 | System and method for providing cost transparency to units of an organization - A system and method provide transparency of costs allocated to a unit of an organization. The method includes steps to receive asset information for an application at a cost transparency engine and identify a direct dependency of the application and an indirect dependency of the application using the asset information for the application. An infrastructure cost for the application is determined based on the direct dependency, the indirect dependency, component consumption by the application, and a unit cost of a service supporting the component. A report is generated, via a reporting tool, presenting the infrastructure cost for the application. | 01-07-2010 |
Denise Johnson, Trenton, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090110758 | COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT LOSS - Compositions, which include psyllium and polyethylene glycol in a weight ratio of psyllium to polyethylene glycol of from about 1:3 to about 2:1, a gum, and one or more additional ingredients selected from the group consisting of water, salt, sweeteners, flavoring agents, and preservatives are presented. | 04-30-2009 |
Douglas Eugene Johnson, Cherry Hill, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20120028861 | METHOD FOR IMPROVING THE DEPOSIT FORMATION RESISTANCE PERFORMANCE OF TURBINE OILS CONTAINING AMINE ANTIOXIDANTS - The deposit formation resistance performance of turbine oils containing amine antioxidants and antiwear additives is enhanced beyond the level of that of turbine oils containing tricresyl phosphate antiwear additive by employing as the antiwear additive a 4,4′-(Isopropylidenediphenyl)bis(diphenyl phosphate). | 02-02-2012 |
Frank Johnson, Bridgewater, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080233156 | Pharmaceutical compositions - Provided herein is a method of treating a condition in a host that is responsive to an agonist, the method comprising administering to the host a multi-layer pharmaceutical composition comprising the agonist and an antagonist thereof, wherein the agonist and antagonist are not in direct contact with one another in the intact form of the composition. | 09-25-2008 |
| 20100151014 | PHARMACEUTICAL COMPOSITION - Provided herein are pharmaceutical compositions comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for treating pain using such compositions are also demonstrated. | 06-17-2010 |
| 20100152221 | PHARMACEUTICAL COMPOSITION - Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for treating pain using such compositions is also demonstrated. | 06-17-2010 |
Franklin Johnson, Bridgewater, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090196890 | PHARMACEUTICAL COMPOSITIONS - Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for treating pain using such compositions is also demonstrated. | 08-06-2009 |
Garry Johnson, Allendale, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110300095 | MALODOR NEUTRALIZING COMPOSITIONS COMPRISING UNDECYLENIC ACID OR CITRIC ACID - Compositions comprising undecylenic acid or citric acid and certain esters are effective for reducing malodors. The esters are in the molecular weight range of between 150-200 when the acid is undecylenic acid and in the range of between 130-230 when the acid is citric acid. These compositions can be used in perfumed products, household products and personal care products. | 12-08-2011 |
Geoffrey Johnson, Aberdeen, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090048353 | PROCESSES USING A SUPPORTED CATALYST - The present invention relates to a catalyst comprising a preferably oxidic, core material, a shell of zinc oxide around said core material, and a catalytically active material in or on the shell, based on one or more of the metals cobalt, iron, ruthenium and/or nickel, preferably a Fischer-Tropsch catalyst, to the preparation of such a catalyst and the use thereof in GTL processes. | 02-19-2009 |
Heather Michelle Johnson, Branchburg, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100310739 | Infused Roasted Seeds And Methods Of Making Thereof - Roasted infused seeds and a process for preparing roasted infused seeds are described. In one aspect, the roasted infused seeds may have salt, flavors, nutrients, colors, and/or functional ingredients as well as mixtures of these components infused internally into the seed. By infusing such components into the seeds, the methods described herein provide roasted seeds with unique flavors, nutrients, colors, textures, densities, and/or other functionalities. | 12-09-2010 |
Ivy D. Johnson, Lawrenceville, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080253959 | Synthesis crystalline molecular sieves - In a process for synthesizing a crystalline molecular sieve, an aqueous synthesis mixture is produced capable of forming the crystalline molecular sieve. Crystallization of the synthesis mixture is induced so as to form crystals of said molecular sieve in the synthesis mixture and, when crystallization is complete, the molecular sieve crystals are allowed or caused to separate from the remainder of the synthesis mixture to produce a solid phase comprising said molecular sieve crystals and a supernatant liquid phase. The supernatant liquid phase is then decanted from the solid phase to recover the molecular sieve crystals and the crystals are dried without initially being subjected to washing or filtration. | 10-16-2008 |
| 20090112036 | Selective oligomerization of isobutene - A process for oligomerizing isobutene includes contacting a feedstock including isobutene with a catalyst comprising an EMM-10 molecular sieve under conditions effective to oligomerize said isobutene and produce an effluent containing less isobutene than the feedstock. | 04-30-2009 |
Jameelah Johnson, Scotch Plains, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100127053 | Portable Gift Wrapping Combination - The present invention is directed to a gift wrapping combination comprising a sleeve of flexible material having a closed end and an open end, the sleeve having a size and dimensions that substantially conform to those of a gift box. The present invention is also directed to methods of wrapping a gift. | 05-27-2010 |
Jeffrey P. Johnson, Lawrenceville, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080219498 | VISUAL DISCRIMINATION MODEL FOR SINGLE IMAGE APPLICATIONS - A computer implemented method for applying a visual discrimination model for single image applications includes receiving an image, defining a plurality of regions of interest in the image including a first region located to contain a feature or object to be detected and a second region located to encompass a background, determining metrics for visibility of the feature or object, wherein the metrics are determined by generating channel Just-Noticeable Difference (JND) maps for the single image determining JND summary metrics for the plurality of regions, and determining a difference in JND metrics between the plurality of regions, and adjusting parameters of the JND metrics to increase a visibility of the feature or object in the image. | 09-11-2008 |
| 20090103822 | METHOD FOR COMPRESSION OF IMAGE DATA - In a method and device for compression of image data, in particular medical image data, the image data are initially compressed by means of a lossy compression method with a predetermined starting compression factor. The compressed image data are then analyzed to determine a quality value relative to a defined quality measure and the quality value is compared with a desired quality value predetermined relative to a defined quality measure. A new compression of the image data or further compression of the image data already compressed in a preceding step then ensues with a different compression factor and/or with a different compression method when the quality value deviates by a specific degree from the desired quality value. | 04-23-2009 |
J. Erik Johnson, Verona, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090162321 | METHODS FOR PACKAGING PROPAGATION-DEFECTIVE VESICULAR STOMATITIS VIRUS VECTORS USING A STABLE CELL LINE THAT EXPRESSES G PROTEIN - A method of producing propagation-defective Vesicular Stomatitis Virus (VSV) is provided. The method involves providing a cell that includes an optimized VSV G gene, wherein expression of VSV G protein from the optimized VSV G gene is inducible; and inducing the cell to express VSV G protein from the optimized VSV G gene. The method also involves infecting the induced cell with an attenuated VSV; growing the infected cells in culture; and recovering attenuated VSV from the culture. | 06-25-2009 |
| 20090175900 | METHODS FOR PACKAGING PROPAGATION-DEFECTIVE VESICULAR STOMATITIS VIRUS VECTORS - A method of producing propagation-defective Vesicular Stomatitis Virus (VSV) in a cell culture is provided. The method involves introducing a plasmid vector encoding an optimized VSV G gene into a cell; expressing VSV G protein from the optimized VSV G gene; and introducing a propagation-defective VSV into the cell expressing the VSV G protein encoded by the optimized VSV G gene. The method further includes growing the cells in culture; and recovering the propagation-defective VSV from the culture. | 07-09-2009 |
Joel Johnson, Port Monmouth, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110286298 | ADJUSTABLE ORBIT IMBALANCE COMPENSATING ORBITAL SHAKER - An orbital shaker apparatus is provided, including a first shaft connected to a first bearing assembly at a first end and a mounting portion at the other. The first shaft is rotatable about a first shaft axis, and is connected to a motor. The second shaft has a bearing assembly on the mounting portion at one end and a platform at the other, and is aligned parallel to and offset from the first shaft by a distance. A counterweight rotor assembly is coupled to the mounting portion, and rotated by a belt driven by a pulley connected to the rotating shaft of a counterweight motor. The counterweight assembly includes two counterweight bearings, each having a counterweight wedge. The platform also includes supports for objects to be secured thereto. In use, as the counterweight rotor rotates, the second shaft, second bearing assembly, and platform describes a circular orbit with diameter 2R. | 11-24-2011 |
Josish Johnson, Somerville, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100123557 | VEHICLE VIOLATION ENFORCEMENT SYSTEM AND METHOD - A PDA device is used to record the ID of a vehicle boot RFID tag and to transmit to the tag and to a host entity violation data such as summons number, license number, time and date stamp, issuing person ID, location of the vehicle, scofflaw data and so on. This data may be entered into the PDA electronically via a communication network such as the internet or LAN system or manually via a keyboard. The host entity has a data base which is uploaded with this information and has correlation of RFID tag numbers to an unlock combination number for each boot. When the boot is attached to a vehicle this PDA data is transmitted to the host entity whose contact telephone number is attached to the vehicle being booted. The driver contacts the entity to pay the fine and receive in return the unlock combination. The driver thus can release and remove the boot within minutes of returning to the vehicle and can return the boot at his leisure. | 05-20-2010 |
Kristine Erickson Johnson, Basking Ridge, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090136471 | TREATMENT OF PREMATURE BIRTH COMPLICATIONS - The present invention provides methods of treating one or more complications of premature birth suffered by premature infants, comprising administering to the premature infant umbilical cord blood stem cells and, optionally, placental stem cells. The present invention also provides methods of combining and administering, and compositions comprising, umbilical cord blood stem cells, particularly autologous cord blood cells, and placental stem cells for the treatment of premature infants. | 05-28-2009 |
Livingston Johnson, Skillman, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090132288 | SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES - A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results. | 05-21-2009 |
| 20090198504 | RATER RESOURCE ALLOCATION SYSTEMS AND METHODS - Methods of allocating raters to assessment visits of studies, and tangible computer readable media including software that is adapted to control a computer to implement methods of allocating raters to assessment visits of studies, are provided. Raters are allocated by retrieving blinding information that includes at least one blinding criterion for a visit of a study, retrieving rater information for at least one rater associated with the study, comparing the retrieved rater information and the retrieved blinding information to identify one or more raters meeting the at least one blinding criterion and enabling selection of the identified one or more raters for allocation to the visit of the study. A rater may then be allocated to the visit by receiving a selection for at least one of the identified raters and allocating the at least one rater to the visit responsive to the received selection. | 08-06-2009 |
| 20100100397 | SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES - A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results. | 04-22-2010 |
| 20110071853 | SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES - A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results. | 03-24-2011 |
| 20110077962 | SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES - A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results. | 03-31-2011 |
| 20110282692 | SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES - A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results. | 11-17-2011 |
Lois Johnson, Edison, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20120021303 | ELECTRICALLY RECHARGEABLE, METAL-AIR BATTERY SYSTEMS AND METHODS - The invention provides for a fully electrically rechargeable metal-air battery systems and methods of achieving such systems. A rechargeable metal air battery cell may comprise a metal electrode an air electrode, and an aqueous electrolyte separating the metal electrode and the air electrode. In some embodiments, the metal electrode may directly contact the electrolyte and no separator or porous membrane need be provided between the air electrode and the electrolyte. Rechargeable metal air battery cells may be electrically connected to one another through a centrode connection between a metal electrode of a first battery cell and an air electrode of a second battery cell. Air tunnels may be provided between individual metal air battery cells. In some embodiments, an electrolyte flow management system may be provided. | 01-26-2012 |
Paul Thomas Johnson, Sparta, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110162300 | PHOTOVOLTAIC UTILITY BUILDING - A Photovoltaic Utility Building is a structure that is portable to site, permanent power generating system. Multiple adjustable photovoltaic panels including extending panel or panels allow for the additional collection of solar energy on a base. The Photovoltaic Utility Building structure, completely wire with inverter, an A/C disconnect and out put receptacle plug is ready use as it is UL electric certified. | 07-07-2011 |
Robert E. Johnson, Middletown, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100023355 | Method and System of Developing a Product - Aspects of the invention include a method and system to develop a product within a corporate environment comprising diverse business units that are located in geographically dispersed locations. In addition, aspects of the invention provide for a streamlined product development process such that a company can efficiently launch products to market from an idea generation stage. Further aspects of the invention include systems and methods that coordinate product development activities within and between different business units within a company. Additional aspects of the invention provide for systems and methods that improve efficiency, reduce redundancy and provide synergy of expertise between different business units to develop a product. | 01-28-2010 |
Rodney P. Johnson, Highland Lakes, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080294169 | Bone-reaming system - A bone-reaming system for use in bone cavities which allows for a less invasive and more precise surgical procedure is disclosed. An apparatus according to such a system may include a housing, a motor disposed within the housing, and a cutter attached to the motor and extendable through the aperture, wherein the housing is capable of articulating with respect to a bone cavity so as to allow the cutter to cut at least a portion of the bone cavity. A routing guide is used in conjunction with the apparatus to provide a template through which to cut preselected portions of a bone cavity. Also disclosed is a method for using such a bone-reaming system. | 11-27-2008 |
Sigmond G. Johnson, Flemington, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080300264 | SUBSTITUTED THIATRIAZAACENAPHTHYLENE-6-CARBONITRILE KINASE INHIBITORS - The present invention is directed to substituted thiatriazaacenaphthylene-6-carbonitrile compounds of formula (I): | 12-04-2008 |
Steven Frederick Johnson, Basking Ridge, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090065560 | MULTI-PACK OF PRODUCT PACKAGES - A multi-pack of packages of individually packaged products wherein there is a plurality of products packaged in individual paperboard cartons, the paperboard cartons being devoid of applied indicia like printing or coloration applied to the paperboard prior to carton forming. There is no printing of logos, trademarks or other product information prior forming the carton. The cartons do have a product identification that is embossed or debossed into the paperboard material of the cartons. The individual cartons are placed in a stack of two to twenty or more cartons and wrapped with a thermoplastic film material. The thermoplastic film material contains the required product indicia like colors and other decoration and product logos and trademarks. | 03-12-2009 |
Steven R. Johnson, Monmouth Junction, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080227693 | Cyclic Peptide Isolation by Spray Drying - Methods for isolation of a synthetic cyclic peptide by spray drying, including spray drying at elevated temperatures, products made by the methods, and synthetic cyclic peptides preparations with defined characteristics, including an essentially amorphous acid addition salt of Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH in the form of a fine powder with a particle diameter of about 2 to about 20 microns. | 09-18-2008 |
William G. Johnson, Short Hills, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080293058 | Association of GSTM1 with autism and assays and methods based thereon - The present invention provides novel markers and assays for autism based on the association of GSTM1 with autism. The invention relates to the use and application of as a susceptibility marker for autism. GSTM1 may be combined with other markers in methods and assays for diagnosis, prenatal diagnosis, and assessment of autism. The invention further relates to a likelihood ratio test. In addition, the present invention discloses a novel method for identifying individuals who are genetically susceptible to have offspring with autism wherein the genotype of GSTM1, alone or in combination with other genetic markers, is determined. | 11-27-2008 |
| 20100143318 | GSTP1 AS TERATOGENIC ALLELE FOR AUTISM AND ASSAYS AND METHODS BASED THEREON - The present invention provides novel markers and assays for autism based on the association of GSTP1 with prevalence for having a child or children with autism or autistic disease. The invention relates to the use and application of GSTP1 as a susceptibility marker and teratogenic allele for autism. In particular the genotype of GSTP1 at amino acids 105 and 114, corresponding to nucleotides 313 and 341 are determined. GSTP1 may be combined with other markers in methods and assays for monitoring, managing, diagnosis, prenatal diagnosis, and assessment of autism. In addition, the present invention discloses a novel method for identifying individuals who are genetically susceptible to have offspring with autism wherein the genotype of GSTP1, alone or in combination with other genetic markers or other indicators of oxidative stress, is determined. | 06-10-2010 |
| 20110229883 | Biochemical Markers for Disease States and Genes for Identification of Biochemical Defects - The present invention relates to a system utilizing biochemical markers and genetic markers to diagnose, predict, and/or monitor intervention of a number of diseases and conditions that have unresolved oxidative stress as an important component. The present invention relates generally to markers and assays for diagnosing, predicting, and monitoring disease, particularly disease-relevant oxidative stress and lipid metabolites and mediators. The oxidative stress, lipid metabolite and lipid mediator biochemical and genetic markers may be further combined with other disease associated or disease relevant markers in methods and assays for diagnosis, monitoring, and assessment of disease, particularly of complex diseases with multi-component factors. The system, methods and assays are applicable to various diseases, including autism, asthma, and Alzheimer's disease. | 09-22-2011 |