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| 20090116587 | METHOD, SYSTEM AND APPARATUS FOR GENERATING CONSTANT AMPLITUDE ZERO AUTOCORRELATION SEQUENCES - A method, system and apparatus for generating a constant amplitude zero autocorrelation (CAZAC) sequence to be transmitted on a wireless communication channel between a user equipment and a base station within a cellular communication network includes iteratively calculating elements of the CAZAC sequence according to a CAZAC sequence formula until a number of iterations has reached a predetermined iteration value determined in accordance with a number of subcarriers associated with the channel; obtaining a value of particular elements of the CAZAC sequence from a table of stored values at predetermined reset iteration values in order to limit error propagation; and generating the reference signal based upon the elements of the CAZAC sequence. The CAZAC sequence formula is one of a Chu sequence, Frank-Zadoff sequence, Zadoff-Chu (ZC) sequence, and Generalized Chirp-Like (GCL) Sequence. | 05-07-2009 |
| 20090300463 | SYSTEM AND METHOD FOR DETERMINING PARITY BIT SOFT INFORMATION AT A TURBO DECODER OUTPUT - A decoding circuit, is provided, comprising: a turbo decoder configured to receive a input systematic bit soft information values and input parity bit information values, and to generate output systematic bit soft information values and hard decoded bits according to a turbo decoding operation; and a parity bit soft information generation circuit configured to receive the input systematic bit soft information values, the input parity bit soft information values, and the output systematic bit soft information values; to determine initial forward metrics, initial backward metrics, and branch metrics as a function of the input parity bit soft information values and the output systematic bit soft information values; to determine output parity bit soft information values based on the branch metrics, the initial forward metrics, and the initial backward metrics; and to provide the output parity bit soft information values as a signal output. | 12-03-2009 |
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| 20110059870 | Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 03-10-2011 |
| 20110203924 | Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 08-25-2011 |
| 20110269642 | MODULAR ASSAY PLATES, READER SYSTEMS AND METHODS FOR TEST MEASUREMENTS - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 11-03-2011 |
| 20120190590 | Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 07-26-2012 |
| 20120190591 | Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 07-26-2012 |
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| 20100028948 | METHODS OF ADMINISTERING/DOSING ANTI-RSV ANTIBODIES FOR PROPHYLAXIS AND TREATMENT - The present invention encompasses novel antibodies and fragments thereof which immunospecifically bind to one or more RSV antigens and compositions comprising said antibodies and antibody fragments. The present invention encompasses methods preventing respiratory syncytial virus (RSV) infection in a human, comprising administering to said human a prophylactically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention also encompasses methods for treating or ameliorating symptoms associated with a RSV infection in a human, comprising administering to said human a therapeutically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention further encompasses compositions comprising antibodies or fragments thereof that immunospecifically bind to a RSV antigen, and methods using said compositions for detection or diagnosis a RSV infection. | 02-04-2010 |
| 20100189718 | MOLECULES WITH EXTENDED HALF-LIVES, COMPOSITIONS AND USES THEREOF - The present invention provides molecules, including IgGs, non-IgG immunoglobulins, proteins and non-protein agents, that have increased in vivo half-lives due to the presence of an IgG constant domain, or a portion thereof that binds the FcRn, having one or more amino acid modifications that increase the affinity of the constant domain or fragment for FcRn. Such proteins and molecules with increased half-lives have the advantage that smaller amounts and or less frequent dosing is required in the therapeutic, prophylactic or diagnostic use of such molecules. | 07-29-2010 |
| 20100239574 | HIGH POTENCY RECOMBINANT ANTIBODIES AND METHOD FOR PRODUCING THEM - High potency antibodies, including immunologically active fragments thereof, having high kinetic association rate constants and optional high affinities are disclosed, along with methods for producing such antibodies. The high potency antibodies disclosed herein are of either the neutralizing or non-neutralizing type and have specificity for antigens displayed by microorganisms, especially viruses, as well as antigenic sites present on cancer cells and on various types of toxins, and the products of toxins. Processes for producing high potency neutralizing antibodies and increasing the potency of already existing neutralizing antibodies are also described. Methods of using said antibodies in the prevention and/or treatment of diseases, especially diseases induced or caused by viruses, are disclosed. | 09-23-2010 |
| 20100266614 | ULTRA HIGH AFFINITY NEUTRALIZING ANTIBODIES - Ultra high affinity antibodies with binding affinities in the range of 10 | 10-21-2010 |
| 20120070447 | METHODS OF ADMINISTERING / DOSING ANTI-RSV ANTIBODIES FOR PROPHYLAXIS AND TREATMENT - The present invention encompasses novel antibodies and fragments thereof which immunospecifically bind to one or more RSV antigens and compositions comprising said antibodies and antibody fragments. The present invention encompasses methods preventing respiratory syncytial virus (RSV) infection in a human, comprising administering to said human a prophylactically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention also encompasses methods for treating or ameliorating symptoms associated with a RSV infection in a human, comprising administering to said human a therapeutically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention further encompasses compositions comprising antibodies or fragments thereof that immunospecifically bind to a RSV antigen, and methods using said compositions for detection or diagnosis a RSV infection | 03-22-2012 |
| 20120135006 | ULTRA HIGH AFFINITY NEUTRALIZING ANTIBODIES - Ultra high affinity antibodies with binding affinities in the range of 10 | 05-31-2012 |
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| 20090104205 | Human-Murine Chimeric Antibodies Against Respiratory Syncytial Virus - This invention relates to a human antibody which contains the one CDR from each variable heavy and variable light chain of at least one murine monoclonal antibody, against respiratory syncytial virus which is MAb1129 and the use thereof for the prevention and/or treatment of RSV infection. | 04-23-2009 |
| 20110136689 | Dual Expression Vector System for Antibody Expression in Bacterial and Mammalian Cells - The present invention provides a dual expression vector, and methods for its use, for the expression and secretion of a full-length polypeptide of interest in eukaryotic cells, and a soluble domain or fragment of the polypeptide in bacteria. When expressed in bacteria, transcription from a bacterial promoter within a first intron and termination at the stop codon in a second intron results in expression of a fragment of the polypeptide, e.g., a Fab fragment, whereas in mammalian cells, splicing removes the bacterial regulatory sequences located in the two introns and generates the mammalian signal sequence, allowing expression of the full-length polypeptide, e.g., IgG heavy or light chain polypeptide. The dual expression vector system of the invention can be used to select and screen for new monoclonal antibodies, as well as to optimize monoclonal antibodies for binding to antigenic molecules of interest. | 06-09-2011 |
| 20120156195 | Human-Murine Chimeric Antibodies Against Respiratory Syncytial Virus - This invention relates to a human antibody which contains the one CDR from each variable heavy and variable light chain of at least one murine monoclonal antibody, against respiratory syncytial virus which is MAb1129 and the use thereof for the prevention and/or treatment of RSV infection. | 06-21-2012 |
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| 20100270444 | CABINET INSTALLATION ASSEMBLY - A cabinet installation system is characterized by the use of adjustable brackets and rails used to align a wall or base cabinet for mounting the cabinets on a wall. The brackets include horizontal and vertical legs which are connected via a hinge at one end and by an adjustable device at the other end so that the brackets have a triangular configuration. The adjustable device varies the angle between the legs so that when the vertical leg of a bracket is mounted on a wall, the horizontal leg can be adjusted to a level position. Front and rear rails are adjustably connected with the brackets. With the brackets arranged in spaced relation on a wall and the horizontal legs adjusted to level, the rails are adjusted relative to each bracket, respectively, so that the rails are linear, parallel and spaced according to the depth of the cabinet. When a cabinet is aligned relative to the rails, it can be secured to the wall in a straight and level position. | 10-28-2010 |
| 20100270445 | CABINET INSTALLATION ASSEMBLY - A cabinet installation system is characterized by the use of adjustable brackets and rails used to align a wall or base cabinet for mounting the cabinets on a wall. The brackets include horizontal and vertical legs which are connected together at one end and by an adjustable device at the other end so that the brackets have a triangular configuration. The adjustable device varies the angle between the legs so that when the vertical leg of a bracket is mounted on a wall, the horizontal leg can be adjusted to a level position. Front and rear rails are adjustably connected with the brackets. With the brackets arranged in spaced relation on a wall and the horizontal legs adjusted to level, the rails are adjusted relative to each bracket, respectively, so that the rails are linear, parallel and spaced according to the depth of the cabinet. When a cabinet is aligned relative to the rails, it can be secured to the wall in a straight and level position. | 10-28-2010 |
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| 20080300167 | Patched genes and uses related thereto - Methods for isolating patched genes, including the mouse and human patched genes, as well as invertebrate patched genes and sequences, are provided. Decreased expression of patched is associated with the occurrence of human cancers, particularly basal cell carcinomas of the skin. The patched and hedgehog genes are useful in creating transgenic animal models for these human cancers. The patched nucleic acid compositions find use in identifying homologous or related proteins and the DNA sequences encoding such proteins; in producing compositions that modulate the expression or function of the protein; and in studying associated physiological pathways. In addition, modulation of the gene activity in vivo is used for prophylactic and therapeutic purposes, such as treatment of cancer, identification of cell type based on expression, and the like. The DNA is further used as a diagnostic for a genetic predisposition to cancer, and to identify specific cancers having mutations in this gene. | 12-04-2008 |
| 20100221724 | PATCHED POLYPEPTIDES AND USES RELATED THERETO - Methods for isolating patched genes, including the mouse and human patched genes, as well as invertebrate patched genes and sequences, are provided. Decreased expression of patched is associated with the occurrence of human cancers, particularly basal cell carcinomas of the skin. The patched and hedgehog genes are useful in creating transgenic animal models for these human cancers. The patched nucleic acid compositions find use in identifying homologous or related proteins and the DNA sequences encoding such proteins; in producing compositions that modulate the expression or function of the protein; and in studying associated physiological pathways. In addition, modulation of the gene activity in vivo is used for prophylactic and therapeutic purposes, such as treatment of cancer, identification of cell type based on expression, and the like. The DNA is further used as a diagnostic for a genetic predisposition to cancer, and to identify specific cancers having mutations in this gene. | 09-02-2010 |
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| 20090165032 | Method And Apparatus For Managing Broadcasting Services Using Broadcast Tokens - A method of managing radio broadcasting services includes: generating a broadcast token including information for associating a service with one or more subscriber groups, using the broadcast token to configure a transmission of the service by a broadcaster, and broadcasting the service to the subscriber group. At the broadcaster, the service can be configured by using parameters in the broadcast token to retrieve service content from a resource manager. | 06-25-2009 |
| 20090259925 | Broadcast Equipment Communication Protocol - A method for transmitting data between components of a digital broadcasting system includes: receiving payload data, adding a content layer header to the payload data to form a content layer data frame, adding a transmission and authentication layer header and a cyclic redundancy check field to the content layer data frame to form a transmission and authentication layer data frame, adding an application framing layer header to the transmission and authentication layer data frame to form an application framing layer data frame, and transmitting the application framing layer data frame to a destination component. | 10-15-2009 |
| 20100056043 | Radio Service Registry - A service registry for a radio broadcasting system includes a memory for storing information relating to services to be provided over the broadcasting system, a processor coupled to the memory, and a core interface for exchanging messages between the processor and a plurality of users, the processor being programmed to retrieve the information from the memory in response to the messages received on the interface, and to output the retrieved information to an importer. A method of broadcasting and a broadcasting system are also provided. | 03-04-2010 |
| 20100265398 | Systems and methods for transmitting media content via digital radio broadcast transmission for synchronized rendering by a receiver - Systems, methods, and processor readable media are disclosed for encoding and transmitting first media content and second media content using a digital radio broadcast system, such that the second media content can be rendered in synchronization with the first media content by a digital radio broadcast receiver. The disclosed systems, methods, and processor-readable media determine when a receiver will render audio and data content that is transmitted at a given time by the digital radio broadcast transmitter, and adjust the media content accordingly to provide synchronized rendering. In exemplary embodiments, these adjustments can be provided by: 1) inserting timing instructions specifying playback time in the secondary content based on calculated delays; or 2) controlling the timing of sending the primary or secondary content to the transmitter so that it will be rendered in synchronization by the receiver. | 10-21-2010 |
| 20110039492 | Digital radio broadcast receiver, broadcasting methods and methods for tagging content of interest - A digital radio broadcast system includes a processing system that receives first audio content, first program data identifying a first item for the first audio content, second audio content, and second program data identifying a second item for the second audio content such that a start of the first program data is received at the processing system within 0.5 seconds of a start of the first audio content. A digital radio broadcast signal including the audio content and the program data is processed for digital radio broadcast transmission via a transmitter. The processing system stops delivery of the first program data to the transmitter upon receipt of the second program data, the first program data thereby being truncated, and begins delivery of the second program data to the transmitter. A digital radio broadcast receiver can tag content of interest based on a user command registered at the receiver. | 02-17-2011 |
| 20120162512 | Systems and Methods for Transmitting Media Content via Digital Radio Broadcast Transmission for Synchronized Rendering by a Receiver - Systems, methods, and processor readable media are disclosed for encoding and transmitting first media content and second media content using a digital radio broadcast system, such that the second media content can be rendered in synchronization with the first media content by a digital radio broadcast receiver. The disclosed systems, methods, and processor-readable media determine when a receiver will render audio and data content that is transmitted at a given time by the digital radio broadcast transmitter, and adjust the media content accordingly to provide synchronized rendering. In exemplary embodiments, these adjustments can be provided by: 1) inserting timing instructions specifying playback time in the secondary content based on calculated delays; or 2) controlling the timing of sending the primary or secondary content to the transmitter so that it will be rendered in synchronization by the receiver. | 06-28-2012 |
