Patent application number | Description | Published |
20090156828 | Novel Compounds and Methods for Forming Taxanes and Using the Same - The present invention is broadly directed to novel compounds useful for the synthesis of biologically active compounds. More particularly, the present embodiments disclosed herein relate to novel side chains, that when coupled to a taxane, are useful for the synthesis of pharmaceutically useful taxanes. Methods of forming the novel side chains and coupling them to hindered alcohols, namely taxanes resulting in useful esters are also disclosed. Various taxanes compounds are known to exhibit anti-tumor activity. | 06-18-2009 |
20090246211 | Molecular constructs suitable for targeted conjugates - The present invention relates generally to effective drug-linker constructs suitable for conjugation with ligands. The present invention also discloses methods of conjugating these constructs with peptides to form the compound of formula I. These methods are readily extended to any hydroxyl, amine or sulfur bearing biologically active molecules. | 10-01-2009 |
20090306400 | CONVERGENT PROCESS FOR THE SYNTHESIS OF TAXANE DERIVATIVES. - The present invention is broadly directed to novel compounds useful for the synthesis of biologically active compounds, including taxane derivatives, and convergent processes for the preparation of these taxane derivatives and their intermediates. | 12-10-2009 |
20100069643 | Convergent Process for the Synthesis of Taxane Derivatives - The application provides a process for the preparation of taxane derivatives and intermediates useful in such processes. | 03-18-2010 |
20120309819 | Acid-Labile Lipophilic Prodrugs of Cancer Chemotherapeutic Agents - The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of chemotherapy associated with the administration of a cancer chemotherapeutic agent to a patient in need thereof. | 12-06-2012 |
20130291430 | Synthesis of High Caloric Fuels and Chemicals - In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. Ketene and ketonization chemistry along with hydrogenation reactions are used to synthesize fuels and chemicals. In another embodiment, ketene used to form fuels and chemicals may be manufactured from acetic acid which in turn can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc. | 11-07-2013 |
20130303601 | Acid-Labile Lipophilic Prodrugs of Cancer Chemotherapeutic Agents - The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of chemotherapy associated with the administration of a cancer chemotherapeutic agent to a patient in need thereof. | 11-14-2013 |
20140245658 | SYNTHESIS OF ETHANOL AND HIGHER ALCOHOLS BY HYDROGENATION OF KETENE - Ketene chemistry and hydrogenation reactions are used to synthesize fuels and chemicals. Ketene from acetic acid is hydrogenated to form fuels and chemicals; acetic acid can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc. In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. | 09-04-2014 |
20140249213 | Acid-Labile Lipophilic Prodrugs of Cancer Chemotherapeutic Agents - The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of chemotherapy associated with the administration of a cancer chemotherapeutic agent to a patient in need thereof. | 09-04-2014 |
20140283438 | Synthesis of High Caloric Fuels and Chemicals - In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. Ketene and ketonization chemistry along with hydrogenation reactions are used to synthesize fuels and chemicals. In another embodiment, ketene used to form fuels and chemicals may be manufactured from acetic acid which in turn can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc. | 09-25-2014 |