Patent application number | Description | Published |
20090263843 | Protein labeling with cyanobenzothiazole conjugates - The invention provides compounds and methods for site-specifically labeling proteins with cyanobenzothiazole derivatives of formula I. For example, the invention provides methods for labeling the N-terminus of a protein that terminates with a cysteine residue. The invention also provides methods for isolating an N-terminally labeled protein and methods for detecting an N-terminally labeled protein. | 10-22-2009 |
20100075351 | BIOLUMINESCENT DETECTION OF CYANOHYDROXY BENZOTHIAZOLE COMPOUNDS - The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. Also provided are novel compounds that can be used in the methods. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format. | 03-25-2010 |
20110223625 | BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS - The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format. | 09-15-2011 |
20120058501 | OXIDIZED GLUTATHIONE ASSAY - The present invention provides an assay for detection of oxidized glutathione (GSSG). | 03-08-2012 |
20130045497 | DETECTION OF HYDROGEN PEROXIDE - The present invention provides compounds useful for detection of hydrogen peroxide and methods of using same. | 02-21-2013 |
20130130289 | COMPOUNDS AND METHODS FOR ASSAYING REDOX STATE OF METABOLICALLY ACTIVE CELLS AND METHODS FOR MEASURING NAD(P)/NAD(P)H - The present invention provides compounds and methods for assaying redox state of metabolically active cells and methods for assaying enzyme activity and/or metabolite level by coupling to redox defining co-factor NAD(P)/NAD(P)H measurement. | 05-23-2013 |
20140093894 | COMPOUNDS AND METHODS FOR ASSAYING REDOX STATE OF METABOLICALLY ACTIVE CELLS AND METHODS FOR MEASURING NAD(P)/NAD(P)H - The present invention provides compounds and methods for assaying redox state of metabolically active cells and methods for assaying enzyme activity and/or metabolite level by coupling to redox defining co-factor NAD(P)/NAD(P)H measurement. | 04-03-2014 |
20140329257 | DETECTION OF HYDROGEN PEROXIDE - The present invention provides compounds useful for detection of hydrogen peroxide and methods of using same. | 11-06-2014 |