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John Gary Montana

John Gary Montana, Essex GB

Patent application numberDescriptionPublished
20090156600Quinolines and Their Therapeutic Use - Compounds of formula [1] are CRTH2 antagonists, useful in the treatment of conditions having an inflammatory component; in which: R06-18-2009
20100093751Indolizineacetic Acids and Their Therapeutic Use as Ligands of the CRTH2 Receptor - Compounds of formula (I) are CRTH2 ligands, useful in the treatment of, inter alia, respiratory diseases: wherein R04-15-2010
20100137300Indolizine Acetic Acid Derivatives as CRTH2 Antagonists - The specific compounds of this list: {7-cyano-2-methyl-1-[4-(morpholine-4-sutfonyl)benzyl]indolizin-3-yl}acetic acid, {1-(3-chloro-4-ethanesulfonylbenzyl)-7-cyano-2-methylindolizin-3-yl}acetic acid, {1-[3-chloro4-(morpholine-4-sulfonyl)benzyl]-7-cyano-2-methylindolizin-3-yl}acetic acid, {1-(3-chloro-4-ethanesulfonylphenylsulfanyl)-7-cyano-2-methylindolizin-3-yl}acetic acid, {1-[3-chloro-4-(morpholine-4-sutfonyl)phenylsutfanyl]-7-cyano-2-methylindolizin-3-yl}acetic acid, {7-cyano-1-(6-fluoroquinolin-2-ylmethyl)-2-methylindolizin-3-yl}acetic acid are ligands of the CRTH2 receptor and are useful in the treatment of respiratory diseases.06-03-2010
20100144786QUINOLINE DERIVATIVES AS CRTH2 RECEPTOR LIGANDS - Specific quinoline derivatives are CRTH2 antagonists, useful in the treatment of conditions having an inflammatory component.06-10-2010
20100144787Quinolines and Their Therapeutic Use - Compounds of formula (I) are CRTH2 ligands, useful in the treatment of, for example, asthma and COPD wherein: R06-10-2010
20110060026Indoles Active on CRTH2 Receptor - Indole derivatives having therapeutic utility are of formula (I): X is —SO03-10-2011
20110071175Indoles and Their Therapeutic Use - Compound of formula (I) are ligands of the CRTH2 receptor, useful inter alia for treatment of inflammatory conditions. Wherein X is —SO03-24-2011

Patent applications by John Gary Montana, Essex GB

John Gary Montana, Hertfordshire GB

Patent application numberDescriptionPublished
20080306109Indolizine Derivatives as Ligands of the Crth2 Receptor - Compounds of formula (I) are CRTH2 antagonists, useful in the treatment of, for example, asthma, chronic obstructive pulmonary disease, rhinitis, allergic airway syndrome, and allergic rhinobronchitis. Formula (I) wherein R12-11-2008

John Gary Montana, Harlow GB

Patent application numberDescriptionPublished
20080242655AZA-INDOLYL COMPOUNDS AND METHODS OF USE - The invention relates to azaindolyl compounds of Formula I with anti-cancer and/or anti-inflammatory activity and more specifically to azaindolyl compounds which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.10-02-2008