| Patent application number | Description | Published |
|---|
| 20090018132 | Substituted Heterocyclic Ethers and Their Use in CNS Disorders - The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders. | 01-15-2009 |
| 20090270405 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS - The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders. | 10-29-2009 |
| 20100099684 | Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands - The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders. | 04-22-2010 |
| 20100222581 | NOVEL ISOPHTHALATES AS BETA-SECRETASE INHIBITORS - There is provided a series of substituted isophthalates of formula (I) | 09-02-2010 |
| 20100240708 | Alpha-(N-Benzenesulfonamido)Cycloalkyl Derivatives - Disclosed are compounds, pharmaceutical compositions containing the compounds, methods for using the compounds and processes for making the compounds. More specifically, the disclosure relates to alpha-(N-benzenesulfonamido)cycloalkyl compounds that may inhibit one or both of: (i) the functioning of a γ-secretase enzyme; or (ii) the production of β-amyloid. Such compounds may be beneficial in the treatment of Alzheimer's disease and other conditions. Representative compounds have the following formula I: | 09-23-2010 |
| 20110015175 | Bicyclic Compounds for the Reduction of Beta-Amyloid Production - The present disclosure provides a series of compounds of the formula (I) | 01-20-2011 |
| 20110105485 | Alpha-(N-Sulfonamido)Acetamide Derivatives as Beta-Amyloid Inhibitors - There is provided a series of novel α-(N-sulfonamido)acetamide compounds of the Formula (I) | 05-05-2011 |
| 20110124662 | Substituted Carbamate Derivatives as Modulators of Corticotropin-Releasing Factor Receptor Activity - The disclosure provides compounds of formula (I), including their salts, as well as compositions and methods of using the compounds. The compounds are CRF receptor antagonists and may be useful for treating disorders associated with abnormal CRF levels or aberrant functioning of CRF receptors. | 05-26-2011 |
