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John Caldwell
John Caldwell, Blacksburg, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20100261994 | INTEGRATION OF VERY SHORT ELECTRIC PULSES FOR MINIMALLY TO NONINVASIVE ELECTROPORATION - The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) or supra-poration to cause cell death in treated tumors. In embodiments, the methods comprise the integration of ultra-short electric pulses, both temporally and spatially, to achieve the desired modality of cell death. | 10-14-2010 |
John Caldwell, Sutton GB
| Patent application number | Description | Published |
|---|---|---|
| 20080275029 | Compounds for Treating Protein-Kinase Mediated Disorders - The invention provides a compound of the formula (I) or a salt, solvate, tautomer or N-oxide thereof for use in the treatment or prophylaxis of a disease state or condition mediated by protein kinase A and/or protein kinase B; | 11-06-2008 |
| 20090099213 | Ortho-Condensed Pyridine and Pyrimidine Derivatives (e.g., Purines) as Protein Kinases Inhibitors - The invention provides a compound for use in the prophylaxis or treatment of a disease state or condition mediated by protein kinase B, the compound having the formula (I): or salts, solvates, tautomers or N-oxides thereof, wherein T is N or CR | 04-16-2009 |
| 20090124610 | PHARMACEUTICAL COMPOUNDS - Compounds of the formula (I), and salts, solvates, tautomers and N-oxide thereof, wherein TG is selected from groups (1) and (2): wherein the asterisk (*) represents the point of attachment of the group E to the group X; R | 05-14-2009 |
| 20090247538 | Ortho-Condensed Pyridine and Pyrimidine Derivatives (e.g., Purines) as Protein Kinases Inhibitors - The invention provides a compound for use as a protein kinase B inhibitor, the compound being a compound of the formula (I) or salts, solvates, tautomers or N-oxides thereof, wherein T is N or CR | 10-01-2009 |
| 20100016340 | PHARMACEUTICAL COMPOUNDS - The invention provides compounds of the formula (I): | 01-21-2010 |
| 20100093748 | SUBSTITUTED PIPERIDINES HAVING PROTEIN KINASE INHIBITING ACTIVITY - The invention provides PKA and PKB kinase-inhibiting compounds of the formula (I): | 04-15-2010 |
| 20100120798 | SUBSTITUTED PIPERIDINES CONTAINING A HETEROARYLAMIDE OR HETEROARYLPHENYL MOIETY - The invention provides compounds of the formula (I) having PKA and PKB kinase inhibiting compounds of the formula (I): GP 1 J T 2 J N 4 R N H (I) or salts, solvates, tautomers or N-oxides thereof, wherein (1) GP is a group GP1: HET 2a a Q G (HNCO)f 7 (R)x N * (GP1) (2) GP is a group GP2: 10 (R)r O 2a a QG (CH2)w N V H N * (GP2) wherein HET is a monocyclic or bicyclic heterocyclic group containing up to 4 heteroatom ring members; the ring V is a monocyclic or bicyclic heteroaryl group of 5 to 10 ring members; and J1, J2, R4, R7, R10, Q2a, Ga, x, w and f are as defined in the claims | 05-13-2010 |
John Caldwell, Ringwood, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090258868 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 10-15-2009 |
| 20090306047 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 12-10-2009 |
John Caldwell, Meridian, ID US
| Patent application number | Description | Published |
|---|---|---|
| 20090002001 | INTEGRATED LIGHT CONDITIONING DEVICES ON A PROBE CARD FOR TESTING IMAGING DEVICES, AND METHODS OF FABRICATING SAME - A probe card is disclosed which includes a body, at least one housing in the body, the housing having at least one light opening, and at least one light conditioning device in the at least one light opening in the housing. A method of forming a probe card is also disclosed which includes forming an opening in a body of the probe card, positioning a housing having a light opening in the opening in the body of the probe card and positioning at least one light conditioning device in the light opening in the housing. | 01-01-2009 |
| 20090289651 | PROBE CARD LAYOUT - Multi-touchdown, parallel test probe cards having probe elements arranged to provide greater efficiency during testing of a substrate having a plurality of die thereon. Probe elements may be arranged in a number of configurations that allow for efficient usage of the probe elements. | 11-26-2009 |
John Caldwell, Austin, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090062932 | Process Model Identification in a Process Control System - Disclosed is a method of controlling and managing a process control system having a plurality of control loops. The method includes implementing a plurality of control routines to control operation of the plurality of control loops, respectively. The plurality of control routines may include at least one non-adaptive control routine. Operating condition data is then collected in connection with the operation of each control loop of the plurality of control loops, and a respective process model is identified for each control loop of the plurality of control loops from the respective operating condition data collected for each control loop of the plurality of control loops. In some embodiments, the identification of the respective process models may be automatic as a result of a detected process change or be on-demand as a result of an injected parameter change. | 03-05-2009 |