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John B. Robbins

John B. Robbins, New York, NY US

Patent application numberDescriptionPublished
20100150954VACCINES AGAINST INFLUENZA VIRUS - Disclosed are immunogenic conjugates having the general formula:06-17-2010
20100272757BACILLUS ANTHRACIS PROTECTIVE ANTIGEN NUCLEIC ACID SEQUENCES - The invention relates to improved methods of producing and recovering B. anthracisprotective antigen (PA), especially modified PA which is protease resistant, and to methods of using of these PAs or nucleic acids encoding these PAs for eliciting an immunogenic response in humans, including responses which provide protection against, or reduce the severity of, 10-28-2010
20100330074USE OF SACCHARIDES CROSS-REACTIVE WITH BACILLUS ANTHRACIS SPORE GLYCOPROTEIN AS A VACCINE AGAINST ANTHRAX - Provided are immunogenic compositions and methods for eliciting an immune response against 12-30-2010

John B. Robbins, Chevy Chase, MD US

Patent application numberDescriptionPublished
20090232840VACCINES AGAINST ESCHERICHIA COLI O157 INFECTION - This invention relates to conjugates of the O-specific polysaccharide of 09-17-2009
20100062023CHOLESTEROL-CONTAINING COMPOUNDS AND THEIR USE AS IMMUNOGENS AGAINST BORRELIA BURGDORFERI - Unique compounds that can be used for inducing an immune response to 03-11-2010
20100239601METHOD OF IMMUNIZING HUMANS AGAINST SALMONELLA TYPHI USING A VI-REPA CONJUGATE VACCINE - This invention relates to conjugates of the Vi polysaccharide of 09-23-2010

Patent applications by John B. Robbins, Chevy Chase, MD US

John B. Robbins, Bethesda, MD US

Patent application numberDescriptionPublished
20100040644METHODS FOR PREPARING IMMUNOGENIC CONJUGATES - Methods for making an immunogenic conjugate that includes a hapten or an antigen covalently linked to a carrier. The methods include reacting a first agent with a dihydrazide resulting in a hydrazine-modified first agent, wherein the first agent is a hapten, an antigen or a carrier; reacting a second agent with a benzaldehyde compound resulting in a benzaldehyde-modified second agent, wherein the second agent is a hapten, an antigen or a carrier, provided that the first agent or the second agent is a carrier; and reacting the hydrazine-modified first agent with the benzaldehyde-modified second agent resulting in an immunogenic conjugate comprising a hapten or an antigen covalently linked to a carrier via a hydrazone linkage.02-18-2010
20100183678CONJUGATES OF PLASMODIUM FALCIPARUM SURFACE PROTEINS AS MALARIA VACCINES - Conjugates of ookinete surface protein Pfs25 are provided that are efficacious as vaccines against 07-22-2010

John B. Robbins, Mckinney, TX US

Patent application numberDescriptionPublished
20090243122ALIGNMENT MARK FOR OPAQUE LAYER - An IC alignment mark in a contact metal layer for use under an opaque layer, and a process for forming the alignment mark, are disclosed. The alignment mark includes contact metal fields, each several microns wide, with an array of PMD pillars in the interior, formed during contact etch, contact metal deposition and selective contact metal removal processes. The pillars are arrayed such that all exposed surfaces of the contact metal are planar. One configuration is a rectangular array in which every other row is laterally offset by one-half of the column spacing. Horizontal dimensions of the pillars are selected to maximize the contact metal fill factor, while providing sufficient adhesion to the underlying substrate during processing. The contact metal is at least 15 nanometers lower than the PMD layer surrounding the alignment mark, as a result of the contact metal removal process.10-01-2009