| Patent application number | Description | Published |
|---|
| 20080242774 | MULTIPHASIC NANO-COMPONENTS COMPRISING COLORANTS - Multiphasic colorant nano-components (MPCs) having at least two phases and at least one colorant are provided. In certain aspects, the at least two phases are optically or visually distinct from one another. The MPCs can be used in various methods in various applications, such as visual, optical, and/or electronic displays, including in paints, inks, coatings, plastics, textiles, electronic display devices, pixels, or electronic paper. The MPCs are formed by methods of electrified jetting of polymers. | 10-02-2008 |
| 20080269456 | MULTIFUNCTIONAL CVD COATINGS - Multifunctional reactive polymers created by chemical vapor deposition (CVD) and methods of making such polymeric systems are provided. Such polymers provide multifunctional surfaces which can present two or more different molecules (e.g. biological ligands) in controlled ratios. Polymers may include compositional gradients allowing attached ligands to be presented as continuous gradients across a surface. The polymer compositions are modularly designable and applicable to a wider range of applications, including biomedical devices and diagnostic systems. | 10-30-2008 |
| 20090118819 | Nitric Oxide Coatings for Medical Devices - The disclosure provides for devices and coatings that are substantially free of organic solvent sand suitable for insertion into a patient, and that comprise a metal layer and a coating with a thickness of about 20 nm to about 2000 nm wherein the coating comprises a biocompatible polymer comprising at least one residue covalently bonded to a nitric oxide generating compound. | 05-07-2009 |
| 20100015447 | MICROPHASIC MICRO-COMPONENTS AND METHODS FOR CONTROLLING MORPHOLOGY VIA ELECTRIFIED JETTING - The disclosure provides methods for preparation of multiphasic micro-components, such as core-shell or anisotropic (e.g., Janus) multiphasic particles with well-defined structures using electrohydrodynamic co-jetting of two polymer solutions containing polyelectrolytes. Suitable polyelectrolytes include polyacrylic acid (PAA), poly(acrylamide acrylic acid (PAAm), and/or poly(acryl amide-co-acrylic acid) (PAAm-AA), sodium polystyrene sulfonate (PSS), polyethylene imine (PEI), polypeptides, copolymers, and combinations of these. Control of certain variables, such as relative conductivities of the two jetting solutions, controls the particle morphologies formed, leading to a predetermined phase orientation for the same polymer system. In certain aspects, after cross-linking, core-shell particles are stable in aqueous solutions and exhibit reproducible swelling behavior, while maintaining the original core-shell geometry. In addition, micro-components formed in accordance with the present teachings are pH-responsive based on external environmental pH. Thus, such micro-components are useful for a variety of different applications, including micro- and nano-active ingredient delivery systems. | 01-21-2010 |
| 20100038830 | METHODS FOR FORMING BIODEGRADABLE NANOCOMPONENTS WITH CONTROLLED SHAPES AND SIZES VIA ELECTRIFIED JETTING - Methods of forming a plurality multiphasic nano-components (MPNs) having at least two phases, with high selectivity for at least one of shape, size, or phase orientation in the nano-component are provided. The methods provide high yields of substantially similar nano-components by controlling one or more of: polymer concentration, liquid stream composition, liquid stream conductivity, flow rate, humidity, temperature, pressure, electrode design and/or configuration during an electrified jetting process. Such methods of making MPNs form shapes including disks, rods, spheres, rectangles, polygons, toroids, cones, pyramids, cylinders, fibers, and combinations thereof. Such MPNs can be used in various applications, including for medical diagnostics or with pharmaceutical, personal care, oral care, and/or nutritional compositions. | 02-18-2010 |
| 20100068810 | METHODS AND COMPOSITIONS FOR GROWTH OF EMBRYONIC STEM CELLS - The present invention provides methods and compositions for establishing and maintaining growth of undifferentiated stem cells. In particular, the present invention provides synthetic growth matrices for stem cells, wherein said cells are capable of going through multiple passages while remaining in an undifferentiated state. | 03-18-2010 |
| 20100145422 | METHOD FOR MANUFACTURING AN IMPLANTABLE ELECTRONIC DEVICE - A method of manufacturing an implantable electronic device, including: providing a silicon wafer; building a plurality of layers coupled to the wafer including an oxide layer coupled to the silicon wafer; a first reactive parylene layer coupled to the oxide layer, an electrode layer coupled to the first reactive parylene layer, and a second reactive parylene layer, coupled to the electrode layer, that chemically bonds to the first reactive polymer layer, and a second polymer layer coupled to the second reactive parylene layer; coating the plurality of layers with an encapsulation, and modifying the encapsulation and at least one of the plurality of layers to expose an electrode site in the electrode layer. | 06-10-2010 |
| 20110033928 | METHODS AND COMPOSITIONS FOR GROWTH OF CELLS AND EMBRYONIC TISSUE ON A SYNTHETIC POLYMER MATRIX - The present invention provides methods and compositions for establishing and maintaining growth of cells and embryonic tissue on a synthetic polymer matrix. For example, the present invention provides synthetic growth matrices for stem cells, gametes, mature differentiated cells, and embryonic tissue (e.g., blastomeres, embryos, and embryoid bodies). In certain embodiments, the cells are capable of going through multiple passages while remaining in an undifferentiated state as a result of the synthetic polymer matrix. | 02-10-2011 |
| 20110062608 | MULTI-PHASIC NANOPARTICLES - A method of forming mufti-phasic nano-objects involves the jetting of two or more different liquids in side-by-side capillaries thereby generating a composite liquid stream. The composite then exposed to a force field which causes the composite liquid stream to at least partially solidify into a nano-object. The method forms a nano-object having a number of morphologies such as rods, spheres, and fibers. | 03-17-2011 |
