Jia, MA
Chunguang Jia, Acton, MA US
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20130208955 | CLOUD-BASED MEDICAL IMAGE PROCESSING SYSTEM WITH ACCESS CONTROL - According to one embodiment, a cloud server receives over a network a request for accessing three-dimensional (3D) medical image data from a first user, where the cloud server provides image processing services to a plurality of users using a plurality of image processing tools provided by the cloud server. The cloud server determines user privileges of the users for accessing the 3D medical image data, where the user privileges are related to the 3D medical image data. The 3D medical image data was captured by a medical imaging device and stored in a storage associated with the cloud server. The availability of the image processing tools is limited to the user to process the 3D medical image data based on the user privileges. | 08-15-2013 |
Dong Jia, Brookline, MA US
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20090132993 | MODE-SWITCHED VARIABLE SIGNAL ATTRIBUTES IN BLOCK DIAGRAMS - A programming element is provided that defines model attributes in response to mode change events in a graphical modeling environment. Such definition may involve any signal attribute such as dimensions, data types, complexity and sample times. Events that trigger definition of model attributes may be explicit signaling events generated by other elements, elements within the block diagram programming environment, and elements external from the environment. Implicit events may also trigger definition of model attributes, such as a change of attribute in an input signal. | 05-21-2009 |
20130042257 | MODE-SWITCHED VARIABLE SIGNAL ATTRIBUTES IN BLOCK DIAGRAMS - A programming element is provided that defines model attributes in response to mode change events in a graphical modeling environment. Such definition may involve any signal attribute such as dimensions, data types, complexity and sample times. Events that trigger definition of model attributes may be explicit signaling events generated by other elements, elements within the block diagram programming environment, and elements external from the environment. Implicit events may also trigger definition of model attributes, such as a change of attribute in an input signal. | 02-14-2013 |
James Jia, Belmont, MA US
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20160031903 | sGC STIMULATORS - Compounds of Formulae I′ and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed. | 02-04-2016 |
James Jia, Somerville, MA US
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20110150834 | CRTH2 MODULATORS - Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed. The compounds fall within a genus described by formula I: | 06-23-2011 |
20110311483 | CRTH2 MODULATORS - Compounds of Formulae I-1 to I-9 are disclosed, which are modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders. | 12-22-2011 |
20110312945 | CRTH2 MODULATORS - Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed. The compounds fall within a genus described by formula I | 12-22-2011 |
20130178475 | sGC STIMULATORS - Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed. | 07-11-2013 |
20130216552 | CRTH2 MODULATORS - Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed herein. The compounds are described by structural Formula I: | 08-22-2013 |
20130259830 | CRTH2 MODULATORS - Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed. The compounds fall within a genus described by Formula I: | 10-03-2013 |
20140187795 | CRTH2 MODULATORS AND PREPARATION THEREOF - The present invention relates to processes and intermediates for the preparation of compounds useful as CRTH2 antagonists. Compounds prepared by the processes of the invention are of Formula (AI), (All) and Compound (I). | 07-03-2014 |
20150175599 | FAAH Inhibitors - The present disclosure relates to compounds useful as inhibitors of the enzyme Fatty Acid Amide Hydrolase (FAAH). The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment or prevention of various disorders. Compounds of the invention are described in Table 1. | 06-25-2015 |
Jimmy Yi-Jie Jia, Cambridge, MA US
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20080273836 | ULTRAFAST LASER MACHINING SYSTEM AND METHOD FOR FORMING DIFFRACTIVE STRUCTURES IN OPTICAL FIBERS - An ultrafast laser machining system and method to form diffractive structures in optical fibers. The fiber is mounted with its longitudinal axis perpendicular to the beam path of the laser pulses. A region of the fiber is illuminated and then imaged with two cameras. These cameras are aligned substantially orthogonally. A position of the beam spot is determined. The beam spot is aligned to a starting position within the region. This position is within a portion of the fiber to be machined for which the beam path passes through the greatest length of material. The beam spot is scanned along a path designed to pass the beam spot through all of the portion to be machined such that the beam path does not pass through previously machined material. The laser pulses, which have a duration of less than about 1 ns, are generated as the beam spot is scanned. | 11-06-2008 |
Lin Jia, Cambridge, MA US
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20130028553 | 2-PATTERN COMPOUND PHOTONIC CRYSTALS WITH A LARGE, COMPLETE PHOTONIC BAND GAP - 2-pattern photonic crystal and the associated photonic devices are described here. A 2-pattern photonic crystal has a large, complete photonic band gap. It includes a TM sub-structure providing a large TM photonic band gap superimposed on a TE sub-structure providing a large TE photonic band gap. The resulting 2-pattern photonic crystals have complete photonic band gaps larger than 15%, By altering the respective sub-structures, optical devices for different polarizations (TE, TM or both) can be readily designed, and those optical devices can be integrated on the same plane. | 01-31-2013 |
Lin Jia, Boston, MA US
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20150373831 | STRETCHABLE ELECTRONIC SYSTEMS WITH CONTAINMENT CHAMBERS - The present invention provides electronic systems, including device arrays, comprising functional device(s) and/or device component(s) at least partially enclosed via one or more containment chambers, such that the device(s) and/or device component(s) are at least partially, and optionally entirely, immersed in a containment fluid. Useful containment fluids for use in containment chambers of electronic devices of the invention include lubricants, electrolytes and/or electronically resistive fluids. In some embodiments, for example, electronic systems of the invention comprise one or more electronic devices and/or device components provided in free-standing and/or tethered configurations that decouple forces originating upon deformation, stretching or compression of a supporting substrate from the free standing or tethered device or device component. | 12-24-2015 |
Lujun Jia, Foxborough, MA US
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20110149720 | SYSTEM FOR AND METHOD OF PERFORMING RESIDENTIAL GATEWAY DIAGNOSTICS AND CORRECTIVE ACTIONS - A system for and method of system for performing residential gateway diagnostics and corrective actions is presented. In one exemplary embodiment, the method may comprise running one or more diagnostic tests on a residential gateway using a module of the residential gateway, storing a diagnostic test result, analyzing the diagnostic test result, and performing one or more corrective actions in response to the diagnostic test result. | 06-23-2011 |
Lujun Jia, Foxboro, MA US
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20090086688 | REMOTE ACCESS TO A CUSTOMER HOME NETWORK - A wireless application server may receive, from a wireless device, information identifying an application residing on a network device in a home network. The wireless application server may further cause a connection to be established to the application and transfer traffic between the application and the wireless device. | 04-02-2009 |
20140136623 | REMOTE ACCESS TO A CUSTOMER HOME NETWORK - A wireless application server may receive, from a wireless device, information identifying an application residing on a network device in a home network. The wireless application server may further cause a connection to be established to the application and transfer traffic between the application and the wireless device. | 05-15-2014 |
Lujun R. Jia, Foxboro, MA US
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20100198989 | ASSIGNING PRIORITY TO NETWORK TRAFFIC AT CUSTOMER PREMISES - A device may receive a message from a client device and determine whether the message includes particular data. The device may identify an address within a particular address group when the message includes the particular data. The traffic associated with addresses within the particular address group are assigned priority over traffic associated with addresses outside the particular address group. The device may provide the identified address to the client device so that traffic associated with the client device receives priority over other traffic | 08-05-2010 |
Tony Z Jia, Cambridge, MA US
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20140155274 | Single Cell Nucleic Acid Detection and Analysis - Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided. | 06-05-2014 |
Weiyi Jia, Chelmsford, MA US
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20090095940 | High quantum yield infranred phosphors and methods of making phosphors - Embodiments of the present disclosure include Gd | 04-16-2009 |
20110012059 | NOVEL PHOSPHORESCENT PHOSPHORS - Photoluminescent phosphors wherein some of the oxygen anions in the phosphor matrix have been replaced by halides or nitride. In addition, photoluminescent phosphors wherein some of the oxygen anions in the phosphor matrix have been replaced by halides or nitride and a charge compensator has been included. The phosphors are based on green emitting and blue-green emitting aluminates. | 01-20-2011 |
20120119143 | PHOSPHORESCENT COMPOSITIONS, METHODS OF MAKING THE COMPOSITIONS, AND METHODS OF USING THE COMPOSITIONS - Compositions, methods of making compositions, materials including compositions, crayons including compositions, paint including compositions, ink including compositions, waxes including compositions, polymers including compositions, vesicles including the compositions, methods of making each, and the like are disclosed. | 05-17-2012 |
20120256126 | Persistent phosphors of alkaline earths modified by halides and 3d ions - Phosphorescent compositions including silicate of alkaline earth materials which are modified by at least one halide are provided. The phosphorescent compositions may include 3d ions. A variety of embodiments may be realized. The appearance of some embodiments may be glassy (i.e., vitreous). | 10-11-2012 |
20150102262 | SMOOTHING PHOSPHORS FOR AC LED LIGHTING - Disclosed are smoothing phosphors for AC LED lighting that are capable of prolonging the light emission time of an AC LED (or array of AC LEDs) during a ½ cycle response to a phase change of the alternating current to substantially reduce flicker. The smoothing phosphor of the present teachings comprises a matrix represented by the formula: M | 04-16-2015 |
Xiaoting Jia, Cambridge, MA US
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20150044463 | Dynamic In-Fiber Particle Production With Precise Dimensional Control - A fiber is provided that has been thermally drawn from a fiber preform, having a longitudinal-axis length and including at least one core that has a longitudinal core axis parallel to the longitudinal axis and internally disposed to at least one outer fiber cladding material layer along the fiber length. The fiber is fed through a localized heating site having a heating site temperature, T, that is above a melting temperature of the fiber core, with a feed speed, υ | 02-12-2015 |
Xiaoting Jia, Somerville, MA US
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20140371564 | METHODS AND APPARATUS FOR STIMULATING AND RECORDING NEURAL ACTIVITY - Thermal drawing processes can be used to make multifunctional, high-resolution neural probes for neural recording and stimulation. An exemplary neural probe may include one or more conductive fibers or microelectrodes coated with two or more layers of insulating material, at least one of which is partially etched to expose a tip at the neural probe's distal end. The conductive fibers conduct electrical signals (e.g., neural spikes or electrical stimulation) between the tip and the neural probe's proximal end. Optional optical and fluidic waveguides may guide light and fluid, respectively, between the tip and the proximal end. A neural probe may be flexible enough for long-term (chronic) implantation in neural tissue (e.g., the brain) without excessive tissue damage, even during movement of the brain in the skull. The probe may be made from biocompatible materials, such as insulating and conductive polymers, that have negligible (insignificant) interaction with the surrounding tissue. | 12-18-2014 |
Yanwei Jia, Waltham, MA US
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20120088275 | REAGENTS AND METHODS FOR PCR - Modified double-stranded oligonucleotides that have terminal regions on each of their strands, that have a hybrid length of 6-50 nucleotides long, that have a melting temperature Tm of at least 32° C., and that include 2-4 modifying groups, each covalently attached to a different terminal region, preferably to a terminal nucleotide, said modifying groups being polycyclic substituents that do not have bulky portions that are non-planar, said modified olgonucleotide being capable of binding to the 5′ ex-nuclease domains of DNA polymerases and, when included in a PCR or other primer-dependent DNA amplification reaction at a concentration, generally not more than 2000 nM, that is effective for at least one of the functions of suppressing mispriming, increasing polymerase selectivity against 3′ terminal mismatches, increasing polymerase selectivity against AT-rich 3′ ends, reducing scatter among replicates, suppressing polymerase 5′ exonuclease activity, and inhibiting polymerase activity; as well as amplification reaction mixtures containing such modified double-stranded oligonucleotides, and amplification reactions, amplification assays and kits that include such modified double-stranded oligonucleotides. | 04-12-2012 |
20120198576 | METHODS FOR MAKING EMBRYONIC CELLS, EMBRYOS, AND ANIMALS SENSITIZED TO STRESS - Embodiments of the invention are based upon the discovery that exposure of cleavage-stage embryos to a stress inducer, e.g. heat shock or chemical, renders the exposed embryos more sensitive to a secondary treatment with a stress inducer, e.g. heat shock or chemical inducer. Accordingly, the present invention is directed to methods for making embryos, embryonic cells arising from them, and animals and plants that are sensitized to stress, e.g. physiologic or chemical stressors. Methods of screening for inducers and inhibitors of stress using, as test model systems, embryonic cells, embryos, animals, and plants that are sensitized to stress are also disclosed. | 08-02-2012 |
20140024033 | DETECTING NUCLEIC ACID VARIATIONS WITHIN POPULATIONS OF GENOMES - This disclosure relates to amplification and detection of a rare variant or variants of a DNA sequence in an abundant variant of the sequence, such as detection of a low-level somatic mutations and minority alleles in an excess of normal nucleic acid target sequences. | 01-23-2014 |
20150218625 | COMBINATION OF DSDNA BINDING DYE AND PROBES FOR CHARACTERIZATION OF SSDNA SEQUENCES - This invention includes methods for analyzing single-stranded nucleic acid sequences, either RNA sequences or DNA sequences (ssDNA) utilizing dyes that fluoresce when associated with double strands, so-called DNA binding dyes or dsDNA-dyes. Methods according to this invention utilize a dsDNA-dye in combination with one or more hybridization probes that hybridize to a target nucleic acid sequence and that are labeled with a non-fluorescent quencher moiety, for example, a Black Hole quencher. | 08-06-2015 |
20150322503 | Reagents and Methods of PCR - Modified double-stranded oligonucleotides that have terminal regions on each of their strands, that have a hybrid length of 6-50 nucleotides long, that have a melting temperature Tm of at least 32° C., and that include 2-4 modifying groups, each covalently attached to a different terminal region, preferably to a terminal nucleotide, said modifying groups being polycyclic substituents that do not have bulky portions that are non-planar, said modified oligonucleotide being capable of binding to the 5′ exonuclease domains of DNA polymerases and, when included in a PCR or other primer-dependent DNA amplification reaction at a concentration, generally not more than 2000 nM, that is effective for at least one of the functions of suppressing mispriming, increasing polymerase selectivity against 3′ terminal mismatches. increasing polymerase selectivity against AT-rich 3′ ends, reducing scatter among replicates, suppressing polymerase 5′ exonuclease activity, and inhibiting polymerase activity; as well as amplification reaction mixtures containing such modified double-stranded oligonucleotides, and amplification reactions, amplification assays and kits that include such modified double-stranded oligonucleotides. | 11-12-2015 |
Yanwei Jia, Medford, MA US
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20100252118 | MANIPULATION OF FLUIDS, FLUID COMPONENTS AND REACTIONS IN MICROFLUIDIC SYSTEMS - Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply. | 10-07-2010 |
20140246098 | MANIPULATION OF FLUIDS, FLUID COMPONENTS AND REACTIONS IN MICROFLUIDIC SYSTEMS - Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply. | 09-04-2014 |
20150276562 | MANIPULATION OF FLUIDS, FLUID COMPONENTS AND REACTIONS IN MICROFLUIDIC SYSTEMS - Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply. | 10-01-2015 |
Yie Jia, North Grafton, MA US
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20080240303 | MAP DETECTOR WITH A SINGLE STATE METRIC ENGINE - A MAP detector includes a single state metric engine that performs forward and backward processing to produce forward and backward state metrics. The state metric engine includes a plurality of processes that each perform both the forward and the backward processing operations. The system further includes memory that stores the forward and backward state metrics that are produced by the engine in appropriate orders for the forward and backward processing. A number of multiplexers provide the appropriate branch metrics and apriori values to adder strings in each of the processors in accordance with an associated decoding trellis. | 10-02-2008 |
Zhang Jia, Watertown, MA US
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20120206726 | PHOTONIC CRYSTAL SPECTROMETER - Apparatus and methods can include an optical waveguide coupled to a photonic crystal comprising a dielectric material, the photonic crystal located on an exterior surface of the optical waveguide and comprising a first surface including a first array of periodic features on or within the dielectric material, the array extending in at least two dimensions and including an effective dielectric permittivity different from the surrounding dielectric material. In an example, the periodic features include a specified lattice constant, the periodic features configured to extract a portion of propagating optical energy from the waveguide through the photonic crystal, the portion determined at least in part by the specified lattice constant. | 08-16-2012 |