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Jerald C. Sadoff, Washington US
Jerald C. Sadoff, Washington, DC US
| Patent application number | Description | Published |
|---|---|---|
| 20080286852 | Electroporation of Mycobacterium and Overexpression of Antigens in Mycobacteria - Recombinant | 11-20-2008 |
| 20090068222 | METHODS TO INCREASE TRANSGENE EXPRESSION FROM BACTERIAL-BASED DELIVERY SYSTEMS BY CO-EXPRESSING SUPPRESSORS OF THE EUKARYOTIC TYPE I INTERFERON RESPONSE - Bacterial delivery systems with improved transgene expression are provided. The recombinant bacterial delivery systems deliver transgenes of interest and suppressors of the eukaryotic Type I interferon response to eukaryotic cells. Suppression of the eukaryotic Type I interferon response allows improved expression of the encoded transgene. | 03-12-2009 |
| 20090123492 | GENERATION OF NEW BCG VACCINE STRAINS PROTECTING AGAINST THE ESTABLISHMENT OF LATENT MYCOBACTERIUM TUBERCULOSIS INFECTION AND REACTIVATION FROM THE LATENT OR PERSISTENT STATE - A vaccine for treating or preventing the establishment of latent tuberculosis infections is provided. The vaccine comprises a recombinant | 05-14-2009 |
| 20090136534 | NOVEL RECOMBINANT BCG TUBERCULOSIS VACCINE DESIGNED TO ELICIT IMMUNE RESPONSES TO MYCOBACTERIUM TUBERCULOSIS IN ALL PHYSIOLOGICAL STAGES OF INFECTION AND DISEASE - A vaccine against | 05-28-2009 |
| 20090304750 | NOVEL PRIME-BOOST COMBINATIONS OF ATTENUATED MYCOBACTERIUM - The present invention provides vaccine compositions for effective induction of both mucosal and systemic immunity to pathogenic | 12-10-2009 |
| 20100003219 | Methods to Increase Transgene Expression From Bacterial-Based Delivery Systems by Co-Expressing Suppressors of the Eukaryotic Type I Interferon Response - Bacterial delivery systems with improved transgene expression are provided. The recombinant bacterial delivery systems deliver transgenes of interest and suppressors of the eukaryotic Type I interferon response to eukaryotic cells. Suppression of the eukaryotic Type I interferon response allows improved expression of the encoded transgene. | 01-07-2010 |
| 20100047286 | Recombinant BCG strains with enhanced ability to escape the endosome - strains that have an enhanced ability to elicit a Histocompatibility-Class I-restricted CD8 | 02-25-2010 |
| 20100233213 | Recombinant BCG Strains with Enhanced Ability to Escape the Endosome - strains that have an enhanced ability to elicit a MHC-Class I-restricted CD8 | 09-16-2010 |
| 20110086066 | Methods to Increase Transgene Expression From Bacterial-Based Delivery Systems by Co-Expressing Suppressors of the Eukaryotic Type I Interferon Response - Bacterial delivery systems with improved transgene expression are provided. The recombinant bacterial delivery systems deliver transgenes of interest and suppressors of the eukaryotic Type I interferon response to eukaryotic cells. Suppression of the eukaryotic Type I interferon response allows improved expression of the encoded transgene. | 04-14-2011 |
| 20110117124 | ENHANCEMENT OF TRANSGENE EXPRESSION FROM VIRAL-BASED VACCINE VECTORS BY EXPRESSION OF SUPPRESSORS OF THE TYPE I INTERFERON RESPONSE - Viral-based vectors are genetically engineered to express inhibitors of the anti-viral immune system (e.g. inhibitors of the type I interferon response) in order to enhance transgene expression. The transgenes may encode antigens or other therapeutic agents. | 05-19-2011 |
| 20110117133 | Novel Recombinant BCG Tuberculosis Vaccine Designed to Elicit Immune Responses to Mycobacterium Tuberculosis in all Physiological Stages of Infection and Disease - A vaccine against | 05-19-2011 |